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The map label for this gene is lpa-14 [H]

Identifier: 23098416

GI number: 23098416

Start: 1013829

End: 1014527

Strand: Direct

Name: lpa-14 [H]

Synonym: OB0961

Alternate gene names: 23098416

Gene position: 1013829-1014527 (Clockwise)

Preceding gene: 23098415

Following gene: 23098417

Centisome position: 27.93

GC content: 34.05

Gene sequence:

>699_bases
ATGACTATCTATGCTTGTAAATTACCTTCCTATCAAAATTGGCAGGAAGTGCAATTCTACAGCCAATATATTTCACAAAA
AAGAAGAGATAGGATACAGAAATTCAAAAAAGTGGGGGACGCTTATCGTTCCCTCACGAGTGAACTTTTACTTAGAAAGA
TACTATTTGATCAATTTCATCTTGTTGATGTAACTATTTCTACAGATAAACAAGGAAAACCGTATTTACCTTATCATTCA
AATATACATTTTAATCTTTCTCACTCTGGAGCATGGTGTGTATGTGTAGTAGGAGAAAAACAAGTTGGTATTGATATTGA
GTATATTGACGTGATACCTGAAAATTTGATTTTTACAATTCTTTCAGATGAAGAGCTGGCTTCTGAGGATAATTTACACC
ATCTTTTTTTTGAAAAGTGGACAGTCTTGGAAAGCTATTTGAAAATGATAGGGACTGGTCTATATCTCCCGTTAGGGTCT
GTAGAAATGAAATCAACTAGTGATCGAACGTACAGCGTAAAGCATCGTGAAGGAAAGTATCCAGCAGGAACGAGTAACTG
TTATACATTCGACGAAAATTACAAGTTATCGATTTGCACAAGGGAGTTAGATAAAAATATGCATACATGTATCTATCAGT
ATGATTTTGATAAACTAGTAAATTCATCAAAAGGAACGAATCCACAAGCTCTCATTTAG

Upstream 100 bases:

>100_bases
TAGCAATTTCATTTATACTTACGTTTAAAAACCGTCATATTATTAAGCATAGTGATAAACAAACAAATCGTAACTCTATT
AAAGGAGAAAAAGCGGGGTA

Downstream 100 bases:

>100_bases
GGAAAACAGTTAGTTCAATTAACATTCAATTTAAGGAAAACACTCTTCATTTTGTCTATAAATATTTATAAGACATAGGG
AGGGTGTTTTTTATTGACAG

Product: siderophore biosynthesis regulatory protein

Products: NA

Alternate protein names: Lipopeptide antibiotics iturin A and surfactin biosynthesis protein [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTIYACKLPSYQNWQEVQFYSQYISQKRRDRIQKFKKVGDAYRSLTSELLLRKILFDQFHLVDVTISTDKQGKPYLPYHS
NIHFNLSHSGAWCVCVVGEKQVGIDIEYIDVIPENLIFTILSDEELASEDNLHHLFFEKWTVLESYLKMIGTGLYLPLGS
VEMKSTSDRTYSVKHREGKYPAGTSNCYTFDENYKLSICTRELDKNMHTCIYQYDFDKLVNSSKGTNPQALI

Sequences:

>Translated_232_residues
MTIYACKLPSYQNWQEVQFYSQYISQKRRDRIQKFKKVGDAYRSLTSELLLRKILFDQFHLVDVTISTDKQGKPYLPYHS
NIHFNLSHSGAWCVCVVGEKQVGIDIEYIDVIPENLIFTILSDEELASEDNLHHLFFEKWTVLESYLKMIGTGLYLPLGS
VEMKSTSDRTYSVKHREGKYPAGTSNCYTFDENYKLSICTRELDKNMHTCIYQYDFDKLVNSSKGTNPQALI
>Mature_231_residues
TIYACKLPSYQNWQEVQFYSQYISQKRRDRIQKFKKVGDAYRSLTSELLLRKILFDQFHLVDVTISTDKQGKPYLPYHSN
IHFNLSHSGAWCVCVVGEKQVGIDIEYIDVIPENLIFTILSDEELASEDNLHHLFFEKWTVLESYLKMIGTGLYLPLGSV
EMKSTSDRTYSVKHREGKYPAGTSNCYTFDENYKLSICTRELDKNMHTCIYQYDFDKLVNSSKGTNPQALI

Specific function: May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide a

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR004568 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27019; Mature: 26888

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYACKLPSYQNWQEVQFYSQYISQKRRDRIQKFKKVGDAYRSLTSELLLRKILFDQFH
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LVDVTISTDKQGKPYLPYHSNIHFNLSHSGAWCVCVVGEKQVGIDIEYIDVIPENLIFTI
EEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCEEEEE
LSDEELASEDNLHHLFFEKWTVLESYLKMIGTGLYLPLGSVEMKSTSDRTYSVKHREGKY
ECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCEEEEEECCCCC
PAGTSNCYTFDENYKLSICTRELDKNMHTCIYQYDFDKLVNSSKGTNPQALI
CCCCCCEEEECCCCEEEEEHHHHCCCCEEEEEEECHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TIYACKLPSYQNWQEVQFYSQYISQKRRDRIQKFKKVGDAYRSLTSELLLRKILFDQFH
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LVDVTISTDKQGKPYLPYHSNIHFNLSHSGAWCVCVVGEKQVGIDIEYIDVIPENLIFTI
EEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCEEEEE
LSDEELASEDNLHHLFFEKWTVLESYLKMIGTGLYLPLGSVEMKSTSDRTYSVKHREGKY
ECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCEEEEEECCCCC
PAGTSNCYTFDENYKLSICTRELDKNMHTCIYQYDFDKLVNSSKGTNPQALI
CCCCCCEEEECCCCEEEEEHHHHCCCCEEEEEEECHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8939709 [H]