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The map label for this gene is dhbB [H]

Identifier: 23098412

GI number: 23098412

Start: 1004183

End: 1005067

Strand: Direct

Name: dhbB [H]

Synonym: OB0957

Alternate gene names: 23098412

Gene position: 1004183-1005067 (Clockwise)

Preceding gene: 23098411

Following gene: 23098413

Centisome position: 27.66

GC content: 36.05

Gene sequence:

>885_bases
ATGTCAATACCGTCTATAGCAAGTTATACATTACCAACAGAAAATGAATTACCAAAAAGTAAAGTGGATTGGAAAGCAGA
GGCAAGCCGTTCCGTATTATTAATTCATGATATGCAACAATACTTTTTAGATTTTTATGGTCAAGATTCGCCTCTTATTC
AACAATTGATACAAAATATATCGACGATAAAAGAGACATGTACAAAGCTTGGAATCCCTACAATTTATACTGCACAACCT
GGAGATCAAAACCAAGAAGATCGAGCGTTACTTACAGATTTTTGGGGACCAGGTCTAGATGATGATATAGAGCAGACAAA
AATTACCGACCAATTGGCACCAACGGAAGACGACATGGTACAGACGAAGTGGAGATATAGTGCATTTAAGAAATCACAAC
TATTGGAATGGATGCAGGAAAACGGGAAGGATCAATTAATCATTTGTGGTGTCTATGCCAATATTGGCTGTATTGTTACT
GCGGTTGAAGCATTTATGAGTGATATTCAACCATTTATTGTTGCAGATGCGATGGCAGATTTTTCGAAGGAACAACATGA
AGAAGCATTAGTGTTTGGAGCAGGACGTTGTGCAAGACCATTAATGATGAAGCAATTAATAGAGGATATTTCATCTGAAG
AAACAATTACGGTGCAATCGATTAAAGTACAAGTAGCAGAAATGTTGGAAGTTTCACCGGATCAATTAAATGAGCAAGAT
GACTTAATTGAAAGTGGATTGGATTCGATTCGAATTATGATGCTAGCAGAAGATTGGAGTTCTAAAGGAATAGATATAAG
TTTTATAGAAATGATTGAATCTCCTACGTTAGAAGCGTGGTATCAAAAATTAGTTCCAGAATACGAAACCATACAGGTAA
AGTAA

Upstream 100 bases:

>100_bases
CGTTTTCCATATACAGCACTAGGTAAGGTGAGTAAGAAAAACTTAAGAGCAATGATAAAAGAAAAAATCACACAAAAAAG
TTATTAAGGAGAGATAAATA

Downstream 100 bases:

>100_bases
GGGGATGTTTTAGGTGATTGAAACAATGAAGAATTATCCAATATCTGATGCCCAAGCTGGAATATGGTTTGCGCATCAAT
TGGATACGACAAGTGCTAGT

Product: isochorismatase

Products: NA

Alternate protein names: 2,3 dihydro-2,3 dihydroxybenzoate synthase; Superoxide-inducible protein 1; SOI1 [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSIPSIASYTLPTENELPKSKVDWKAEASRSVLLIHDMQQYFLDFYGQDSPLIQQLIQNISTIKETCTKLGIPTIYTAQP
GDQNQEDRALLTDFWGPGLDDDIEQTKITDQLAPTEDDMVQTKWRYSAFKKSQLLEWMQENGKDQLIICGVYANIGCIVT
AVEAFMSDIQPFIVADAMADFSKEQHEEALVFGAGRCARPLMMKQLIEDISSEETITVQSIKVQVAEMLEVSPDQLNEQD
DLIESGLDSIRIMMLAEDWSSKGIDISFIEMIESPTLEAWYQKLVPEYETIQVK

Sequences:

>Translated_294_residues
MSIPSIASYTLPTENELPKSKVDWKAEASRSVLLIHDMQQYFLDFYGQDSPLIQQLIQNISTIKETCTKLGIPTIYTAQP
GDQNQEDRALLTDFWGPGLDDDIEQTKITDQLAPTEDDMVQTKWRYSAFKKSQLLEWMQENGKDQLIICGVYANIGCIVT
AVEAFMSDIQPFIVADAMADFSKEQHEEALVFGAGRCARPLMMKQLIEDISSEETITVQSIKVQVAEMLEVSPDQLNEQD
DLIESGLDSIRIMMLAEDWSSKGIDISFIEMIESPTLEAWYQKLVPEYETIQVK
>Mature_293_residues
SIPSIASYTLPTENELPKSKVDWKAEASRSVLLIHDMQQYFLDFYGQDSPLIQQLIQNISTIKETCTKLGIPTIYTAQPG
DQNQEDRALLTDFWGPGLDDDIEQTKITDQLAPTEDDMVQTKWRYSAFKKSQLLEWMQENGKDQLIICGVYANIGCIVTA
VEAFMSDIQPFIVADAMADFSKEQHEEALVFGAGRCARPLMMKQLIEDISSEETITVQSIKVQVAEMLEVSPDQLNEQDD
LIESGLDSIRIMMLAEDWSSKGIDISFIEMIESPTLEAWYQKLVPEYETIQVK

Specific function: Required For Production Of 2,3-Dhb. Also Serves As An Aryl Carrier Protein And Plays A Role In Enterobactin Assembly. [C]

COG id: COG1535

COG function: function code Q; Isochorismate hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Escherichia coli, GI1786811, Length=287, Percent_Identity=45.2961672473868, Blast_Score=280, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR016291
- InterPro:   IPR000868
- InterPro:   IPR006163 [H]

Pfam domain/function: PF00857 Isochorismatase; PF00550 PP-binding [H]

EC number: =3.3.2.1 [H]

Molecular weight: Translated: 33324; Mature: 33193

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPSIASYTLPTENELPKSKVDWKAEASRSVLLIHDMQQYFLDFYGQDSPLIQQLIQNI
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHH
STIKETCTKLGIPTIYTAQPGDQNQEDRALLTDFWGPGLDDDIEQTKITDQLAPTEDDMV
HHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHH
QTKWRYSAFKKSQLLEWMQENGKDQLIICGVYANIGCIVTAVEAFMSDIQPFIVADAMAD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FSKEQHEEALVFGAGRCARPLMMKQLIEDISSEETITVQSIKVQVAEMLEVSPDQLNEQD
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHCCCHH
DLIESGLDSIRIMMLAEDWSSKGIDISFIEMIESPTLEAWYQKLVPEYETIQVK
HHHHHCHHHEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure 
SIPSIASYTLPTENELPKSKVDWKAEASRSVLLIHDMQQYFLDFYGQDSPLIQQLIQNI
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHH
STIKETCTKLGIPTIYTAQPGDQNQEDRALLTDFWGPGLDDDIEQTKITDQLAPTEDDMV
HHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHH
QTKWRYSAFKKSQLLEWMQENGKDQLIICGVYANIGCIVTAVEAFMSDIQPFIVADAMAD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FSKEQHEEALVFGAGRCARPLMMKQLIEDISSEETITVQSIKVQVAEMLEVSPDQLNEQD
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHCCCHH
DLIESGLDSIRIMMLAEDWSSKGIDISFIEMIESPTLEAWYQKLVPEYETIQVK
HHHHHCHHHEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377; 9298659 [H]