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The map label for this gene is dhbC [H]

Identifier: 23098410

GI number: 23098410

Start: 1001360

End: 1002556

Strand: Direct

Name: dhbC [H]

Synonym: OB0955

Alternate gene names: 23098410

Gene position: 1001360-1002556 (Clockwise)

Preceding gene: 23098409

Following gene: 23098411

Centisome position: 27.58

GC content: 36.34

Gene sequence:

>1197_bases
ATGTCTGTAAAGACGTTAAATGAAGAGCAACAATTAATTAATCAATATAGTCAAGAAGATTACTTATTGTCTTTTCCAAG
CAAATGCATTTTAGGTAAAGGGAAAGCAGTTGAACTAACTAATTCGGAACAAAACGGATTGCCATTTAGCAAAAGAATCG
AATCCCTTCTACATAAAGGAACATTGAATGGGATGGAAAATCCAATTGTTATTGGTGCTTTGCCATTTCATCAACAAGAT
AAAGGGACATTAGTTATACCAGAAGAAATTCAGCAATCAGAAGTACAACAAATTGTAGATAATTCATTGTCATCAGATAA
TGTCTCTTCAACACATATACAATCGATTCCCTCTGGTAAGGAATATGCAAAAGCAGTGGAGAGGGTTACGAAAGAAATTC
AACAAGGAAAGTTAGAAAAAGCGGTTCTTGGCAGGGTTCTACAAATAGATGTAGACAAGCAACCAACTATTTCACAACTC
GTTCAGAACCTAATTACACATAATCATGATAAGTATAATTTTGCCTTAAATACATCAGAAGAAAATAAAGAAAAAACATT
AATTGGTGCTAGTCCAGAATTATTAATTTCCAAAAAAGGAAGCATCGTTGTTTCCAACCCTTTGGCCGGATCGCGTCCAA
GGCAAAAAGATCCAGAAAAAGATGTATTAATGGCGCAGGAATTACGCCATTCAGAAAAAGATTTGCATGAACATAAGCTT
GTTGTTCAGTCTGTAGCAAATGCATTGCGACCTTTTTGCAAGGAGTTACATGTACCAAAAGAACCATCTATCATTCATAC
AGAGACAATGTGGCATCTTTCAACAGAAATCATTGGTCATTTAGAAGATCCGTTTACACAATCAATTGAAATAGCTGAAA
ATTTGCATCCAACACCAGCGATATGTGGAACTCCAAACGATATTGCATTGGAGAACATTAAGCAGCTTGAACCATTTAAC
CGAGAATATTTTACCGGTTTAATTGGTTGGAGCGATAAAAATGGAGATGGTGAATGGGCGATTACAATTCGCTGTGCGGA
GATAGAACAAAATAGGATTCGTATGTTTGCAGGTGCAGGAGTTGTACAAGATTCAGTCCCAGAAGAAGAAAAAAACGAAA
CGGCTGCGAAGTTACAAACGATGCTACGTGTATTTGGAATAGATTTTTACGAAGAGGAAGGGAATGGATCATGCTAG

Upstream 100 bases:

>100_bases
CTATCGGATAGTGCAAGTCATATAACCATGAATAATATTGTTGTAGATGGAGGAGCCACATTAGGTGCGCAATAGATGGA
ATTAAAGGGAGCTGAATAGT

Downstream 100 bases:

>100_bases
AAGGGTATAAGCCATGGCCAGAGAATCTTAGAAAGTACTATCAAGAAACTGGTTGCTGGACGGGAGAGACTTTCGGAGGA
ATATTAGAGCAACAAGCTAG

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSVKTLNEEQQLINQYSQEDYLLSFPSKCILGKGKAVELTNSEQNGLPFSKRIESLLHKGTLNGMENPIVIGALPFHQQD
KGTLVIPEEIQQSEVQQIVDNSLSSDNVSSTHIQSIPSGKEYAKAVERVTKEIQQGKLEKAVLGRVLQIDVDKQPTISQL
VQNLITHNHDKYNFALNTSEENKEKTLIGASPELLISKKGSIVVSNPLAGSRPRQKDPEKDVLMAQELRHSEKDLHEHKL
VVQSVANALRPFCKELHVPKEPSIIHTETMWHLSTEIIGHLEDPFTQSIEIAENLHPTPAICGTPNDIALENIKQLEPFN
REYFTGLIGWSDKNGDGEWAITIRCAEIEQNRIRMFAGAGVVQDSVPEEEKNETAAKLQTMLRVFGIDFYEEEGNGSC

Sequences:

>Translated_398_residues
MSVKTLNEEQQLINQYSQEDYLLSFPSKCILGKGKAVELTNSEQNGLPFSKRIESLLHKGTLNGMENPIVIGALPFHQQD
KGTLVIPEEIQQSEVQQIVDNSLSSDNVSSTHIQSIPSGKEYAKAVERVTKEIQQGKLEKAVLGRVLQIDVDKQPTISQL
VQNLITHNHDKYNFALNTSEENKEKTLIGASPELLISKKGSIVVSNPLAGSRPRQKDPEKDVLMAQELRHSEKDLHEHKL
VVQSVANALRPFCKELHVPKEPSIIHTETMWHLSTEIIGHLEDPFTQSIEIAENLHPTPAICGTPNDIALENIKQLEPFN
REYFTGLIGWSDKNGDGEWAITIRCAEIEQNRIRMFAGAGVVQDSVPEEEKNETAAKLQTMLRVFGIDFYEEEGNGSC
>Mature_397_residues
SVKTLNEEQQLINQYSQEDYLLSFPSKCILGKGKAVELTNSEQNGLPFSKRIESLLHKGTLNGMENPIVIGALPFHQQDK
GTLVIPEEIQQSEVQQIVDNSLSSDNVSSTHIQSIPSGKEYAKAVERVTKEIQQGKLEKAVLGRVLQIDVDKQPTISQLV
QNLITHNHDKYNFALNTSEENKEKTLIGASPELLISKKGSIVVSNPLAGSRPRQKDPEKDVLMAQELRHSEKDLHEHKLV
VQSVANALRPFCKELHVPKEPSIIHTETMWHLSTEIIGHLEDPFTQSIEIAENLHPTPAICGTPNDIALENIKQLEPFNR
EYFTGLIGWSDKNGDGEWAITIRCAEIEQNRIRMFAGAGVVQDSVPEEEKNETAAKLQTMLRVFGIDFYEEEGNGSC

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=394, Percent_Identity=36.2944162436548, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI87082077, Length=281, Percent_Identity=27.7580071174377, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787518, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788114, Length=230, Percent_Identity=27.3913043478261, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=265, Percent_Identity=28.6792452830189, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 44499; Mature: 44368

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKTLNEEQQLINQYSQEDYLLSFPSKCILGKGKAVELTNSEQNGLPFSKRIESLLHKG
CCCCCCCHHHHHHHHHCCCCEEEECCCHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
TLNGMENPIVIGALPFHQQDKGTLVIPEEIQQSEVQQIVDNSLSSDNVSSTHIQSIPSGK
CCCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHH
EYAKAVERVTKEIQQGKLEKAVLGRVLQIDVDKQPTISQLVQNLITHNHDKYNFALNTSE
HHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCC
ENKEKTLIGASPELLISKKGSIVVSNPLAGSRPRQKDPEKDVLMAQELRHSEKDLHEHKL
CCCCCEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVQSVANALRPFCKELHVPKEPSIIHTETMWHLSTEIIGHLEDPFTQSIEIAENLHPTPA
HHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ICGTPNDIALENIKQLEPFNREYFTGLIGWSDKNGDGEWAITIRCAEIEQNRIRMFAGAG
CCCCCCHHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEECCC
VVQDSVPEEEKNETAAKLQTMLRVFGIDFYEEEGNGSC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
SVKTLNEEQQLINQYSQEDYLLSFPSKCILGKGKAVELTNSEQNGLPFSKRIESLLHKG
CCCCCCHHHHHHHHHCCCCEEEECCCHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
TLNGMENPIVIGALPFHQQDKGTLVIPEEIQQSEVQQIVDNSLSSDNVSSTHIQSIPSGK
CCCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHH
EYAKAVERVTKEIQQGKLEKAVLGRVLQIDVDKQPTISQLVQNLITHNHDKYNFALNTSE
HHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCC
ENKEKTLIGASPELLISKKGSIVVSNPLAGSRPRQKDPEKDVLMAQELRHSEKDLHEHKL
CCCCCEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVQSVANALRPFCKELHVPKEPSIIHTETMWHLSTEIIGHLEDPFTQSIEIAENLHPTPA
HHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ICGTPNDIALENIKQLEPFNREYFTGLIGWSDKNGDGEWAITIRCAEIEQNRIRMFAGAG
CCCCCCHHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEECCC
VVQDSVPEEEKNETAAKLQTMLRVFGIDFYEEEGNGSC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]