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The map label for this gene is speH

Identifier: 23098393

GI number: 23098393

Start: 985676

End: 986056

Strand: Reverse

Name: speH

Synonym: OB0938

Alternate gene names: 23098393

Gene position: 986056-985676 (Counterclockwise)

Preceding gene: 23098421

Following gene: 23098391

Centisome position: 27.16

GC content: 40.16

Gene sequence:

>381_bases
ATGGATGTATTGGGAAGGCATATCATTGCTGAGCTGTGGGAATGCAACTTAGAAAAGTTAAACAATATCGATTTTATTCG
AGATACATTTGTAGAGGCGGCAGTCTTAGCTGGTGCAGAAGTACGTGAAGTTGTGTTTCATCCATTCGCACCATATGGGA
TAAGCGGTGTCGTTATAATCTCTGAATCCCATTTAACTATCCATAGTTTCCCAGAGCATGGTTATGCAAGTATCGATGTC
TATACATGCGGAGATAAAGTAGATCCAAATATTGCGGTAAAACATATTGCAGATGCCCTCGAATCCAGCGTTGGTCAATT
TAGAGAAATACCACGAGGCATGGGACCTGTGAATGCAAAGCCAATACAAAAAATAAAGTAA

Upstream 100 bases:

>100_bases
TCTTTATTCTAATCTAGAAAAATTGCATAAACAATATAATCGGTTTATACTCATCTATATACGAGTAGTAAATATTTTAT
GTAAGGGGAAGTTTCATCAC

Downstream 100 bases:

>100_bases
GATTACATTGTCCTTCGCTGTGCTTAGCTTGCTTTCAACTCTTTGATTATTAGCCCATCTTCATTATATATGAAGATAAT
TATCGGAATATCAAACTGAT

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MDVLGRHIIAELWECNLEKLNNIDFIRDTFVEAAVLAGAEVREVVFHPFAPYGISGVVIISESHLTIHSFPEHGYASIDV
YTCGDKVDPNIAVKHIADALESSVGQFREIPRGMGPVNAKPIQKIK

Sequences:

>Translated_126_residues
MDVLGRHIIAELWECNLEKLNNIDFIRDTFVEAAVLAGAEVREVVFHPFAPYGISGVVIISESHLTIHSFPEHGYASIDV
YTCGDKVDPNIAVKHIADALESSVGQFREIPRGMGPVNAKPIQKIK
>Mature_126_residues
MDVLGRHIIAELWECNLEKLNNIDFIRDTFVEAAVLAGAEVREVVFHPFAPYGISGVVIISESHLTIHSFPEHGYASIDV
YTCGDKVDPNIAVKHIADALESSVGQFREIPRGMGPVNAKPIQKIK

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_OCEIH (Q8CV19)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691859.1
- ProteinModelPortal:   Q8CV19
- SMR:   Q8CV19
- GeneID:   1016679
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0938
- NMPDR:   fig|221109.1.peg.940
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   PRK03124
- BioCyc:   OIHE221109:OB0938-MONOMER
- BRENDA:   4.1.1.50
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13895; Mature: 13895

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLGRHIIAELWECNLEKLNNIDFIRDTFVEAAVLAGAEVREVVFHPFAPYGISGVVII
CCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEE
SESHLTIHSFPEHGYASIDVYTCGDKVDPNIAVKHIADALESSVGQFREIPRGMGPVNAK
ECCCEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PIQKIK
CCCCCC
>Mature Secondary Structure
MDVLGRHIIAELWECNLEKLNNIDFIRDTFVEAAVLAGAEVREVVFHPFAPYGISGVVII
CCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEE
SESHLTIHSFPEHGYASIDVYTCGDKVDPNIAVKHIADALESSVGQFREIPRGMGPVNAK
ECCCEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PIQKIK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376