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The map label for this gene is yfkJ [H]

Identifier: 23098328

GI number: 23098328

Start: 927058

End: 927543

Strand: Direct

Name: yfkJ [H]

Synonym: OB0873

Alternate gene names: 23098328

Gene position: 927058-927543 (Clockwise)

Preceding gene: 23098326

Following gene: 23098329

Centisome position: 25.54

GC content: 33.13

Gene sequence:

>486_bases
TTGTTGATACGTGTTTTATTTGTTTGCCTTGGAAATATATGTCGTTCTCCAATGGCGGAAGCTATTTTTAAGCATATGCT
TGAAATTGAAAATTTAACTTCAATCATTCAAGTAGACTCTGCTGGAACGGGAGATTGGCATATCGGTAAGCAACCACATC
GCGGAACTAGAAATATCCTGGGTAATAAGGGTATTTCATACAAGAATATATATGCCAGACAAATGGAGAAAAATGATTGG
AAAAAATTTGATTATATTATTGTCATGGATGAGCAGAATATAAAGGAATTGCAAAAACTTCAATCAAATAAAGGTATGAC
TATTGCTCGTTTACTGGATTTTGTAGAAGGTTCACAAGTATGTAATGTTCCCGATCCTTATTTTAATGGGGATTTTGAAT
ACGCGTATCAACTTATATTAAGTGGATGTCAACATTTACTTCAATTTTTAAAAGAAAGCCATCAATTAACGGATAAGGAG
AGATGA

Upstream 100 bases:

>100_bases
AGGAAATTTAATACATTTTATATTTTTTATCGAAATTTACATGTATTTGCTTATCAAATCTAGTCGCTTATAATAGAATA
AAAAGAGAAAGAGGTGGAAA

Downstream 100 bases:

>100_bases
ATCATGGGTAAACGTAAAATCTTACTTGGAATGGTAGTCGGAGCAGTTGCAGGTGGTGCAACCGCATTAATAGATAAGGA
ATCAAGAGATTATGCAAAGA

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MLIRVLFVCLGNICRSPMAEAIFKHMLEIENLTSIIQVDSAGTGDWHIGKQPHRGTRNILGNKGISYKNIYARQMEKNDW
KKFDYIIVMDEQNIKELQKLQSNKGMTIARLLDFVEGSQVCNVPDPYFNGDFEYAYQLILSGCQHLLQFLKESHQLTDKE
R

Sequences:

>Translated_161_residues
MLIRVLFVCLGNICRSPMAEAIFKHMLEIENLTSIIQVDSAGTGDWHIGKQPHRGTRNILGNKGISYKNIYARQMEKNDW
KKFDYIIVMDEQNIKELQKLQSNKGMTIARLLDFVEGSQVCNVPDPYFNGDFEYAYQLILSGCQHLLQFLKESHQLTDKE
R
>Mature_161_residues
MLIRVLFVCLGNICRSPMAEAIFKHMLEIENLTSIIQVDSAGTGDWHIGKQPHRGTRNILGNKGISYKNIYARQMEKNDW
KKFDYIIVMDEQNIKELQKLQSNKGMTIARLLDFVEGSQVCNVPDPYFNGDFEYAYQLILSGCQHLLQFLKESHQLTDKE
R

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=155, Percent_Identity=38.0645161290323, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI4757714, Length=155, Percent_Identity=38.0645161290323, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=42.8571428571429, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=152, Percent_Identity=36.8421052631579, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=37.8205128205128, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI78706766, Length=160, Percent_Identity=38.125, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI78706768, Length=160, Percent_Identity=38.125, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI78706770, Length=150, Percent_Identity=36.6666666666667, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706772, Length=150, Percent_Identity=36.6666666666667, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=39.2307692307692, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648069, Length=94, Percent_Identity=40.4255319148936, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18641; Mature: 18641

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRVLFVCLGNICRSPMAEAIFKHMLEIENLTSIIQVDSAGTGDWHIGKQPHRGTRNIL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
GNKGISYKNIYARQMEKNDWKKFDYIIVMDEQNIKELQKLQSNKGMTIARLLDFVEGSQV
CCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCC
CNVPDPYFNGDFEYAYQLILSGCQHLLQFLKESHQLTDKER
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLIRVLFVCLGNICRSPMAEAIFKHMLEIENLTSIIQVDSAGTGDWHIGKQPHRGTRNIL
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
GNKGISYKNIYARQMEKNDWKKFDYIIVMDEQNIKELQKLQSNKGMTIARLLDFVEGSQV
CCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCCC
CNVPDPYFNGDFEYAYQLILSGCQHLLQFLKESHQLTDKER
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]