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The map label for this gene is fruR [H]

Identifier: 23098295

GI number: 23098295

Start: 891932

End: 892678

Strand: Reverse

Name: fruR [H]

Synonym: OB0840

Alternate gene names: 23098295

Gene position: 892678-891932 (Counterclockwise)

Preceding gene: 23098297

Following gene: 23098294

Centisome position: 24.59

GC content: 34.27

Gene sequence:

>747_bases
GTGTTAACCGATGAGAGACATAGACTAATTTTGAAGAAACTAAATGAAAGCGGTGTAGTTAAGTCCTTCGATCTTATAAA
CGATCTTAATTGTTCTGAATCTACAATAAGAAGAGATTTAGCACAATTGGAAGAAGAAGGAATGCTAACTCGAATACACG
GAGGAGCAAAAAAACACTATTCATTCGATAAAGAACCAACCTACCAAGAAAAAACAATCAAAAACGTTCAACATAAAACT
TCTATTGGAAAATTTGCAGCATCGTTAATAGAGGAAAATGATGTTATTTATTTAGATGCAGGAACAACTACACTAGAAAT
AATTCCTTATTTGCCAGATATCCCTTTAACAGTTGTTACGAATGGAATTGTTCACGCATCGATGCTTGCAACTAAACAAA
TCCCTTCTTATTTAGTTGGAGGAAAATTGAAGCACTCTACAAACGCAATAGTTGGAGCAAATAGTCTAATCCAATTAAAG
GAATATCAATTTACTAAAACATTTCTTGGCGTTAATGGCATTGATTTGCGATATGGGTGTACTACGGCGGATCCAGAAGA
AGCAGCCATGAAGAATTTAGCATTACAACAATCAGCAACCACATATATGCTTGCTGATGAAAGTAAATGGAACAACGTTA
ACTTTGCAAAAATCTGTGATATTAATGAAGTTAACTTTATTATAGAAAAACTGACACCCACACACGAACCTTTTCAACCT
CATACTAACATCTTGGAGGCAACATAA

Upstream 100 bases:

>100_bases
ATTAAAATCTTCTACATATATAAATGAAAATGAATGTTTTTGATTGTTTATGATTGTTTTATATATATGCCAATGTTATT
ATGATGATTGAGGTGATGAT

Downstream 100 bases:

>100_bases
ATGATTTACACAATAACTCTTAATCCATCGATTGACTTCATTGTACCTGTCGATCAACTGAAACTTGGAAAGCTAAACTA
CATGAACGATGAGTATAAAG

Product: transcriptional repressor of fructose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLTDERHRLILKKLNESGVVKSFDLINDLNCSESTIRRDLAQLEEEGMLTRIHGGAKKHYSFDKEPTYQEKTIKNVQHKT
SIGKFAASLIEENDVIYLDAGTTTLEIIPYLPDIPLTVVTNGIVHASMLATKQIPSYLVGGKLKHSTNAIVGANSLIQLK
EYQFTKTFLGVNGIDLRYGCTTADPEEAAMKNLALQQSATTYMLADESKWNNVNFAKICDINEVNFIIEKLTPTHEPFQP
HTNILEAT

Sequences:

>Translated_248_residues
MLTDERHRLILKKLNESGVVKSFDLINDLNCSESTIRRDLAQLEEEGMLTRIHGGAKKHYSFDKEPTYQEKTIKNVQHKT
SIGKFAASLIEENDVIYLDAGTTTLEIIPYLPDIPLTVVTNGIVHASMLATKQIPSYLVGGKLKHSTNAIVGANSLIQLK
EYQFTKTFLGVNGIDLRYGCTTADPEEAAMKNLALQQSATTYMLADESKWNNVNFAKICDINEVNFIIEKLTPTHEPFQP
HTNILEAT
>Mature_248_residues
MLTDERHRLILKKLNESGVVKSFDLINDLNCSESTIRRDLAQLEEEGMLTRIHGGAKKHYSFDKEPTYQEKTIKNVQHKT
SIGKFAASLIEENDVIYLDAGTTTLEIIPYLPDIPLTVVTNGIVHASMLATKQIPSYLVGGKLKHSTNAIVGANSLIQLK
EYQFTKTFLGVNGIDLRYGCTTADPEEAAMKNLALQQSATTYMLADESKWNNVNFAKICDINEVNFIIEKLTPTHEPFQP
HTNILEAT

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=230, Percent_Identity=31.7391304347826, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI226510968, Length=230, Percent_Identity=31.7391304347826, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788069, Length=220, Percent_Identity=28.1818181818182, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789059, Length=227, Percent_Identity=28.6343612334802, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789170, Length=208, Percent_Identity=31.25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789829, Length=229, Percent_Identity=27.5109170305677, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=26.8722466960352, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787063, Length=242, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=207, Percent_Identity=26.5700483091787, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=24.0343347639485, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27725; Mature: 27725

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDERHRLILKKLNESGVVKSFDLINDLNCSESTIRRDLAQLEEEGMLTRIHGGAKKHY
CCCCHHHHHHHHHCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHCC
SFDKEPTYQEKTIKNVQHKTSIGKFAASLIEENDVIYLDAGTTTLEIIPYLPDIPLTVVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHH
NGIVHASMLATKQIPSYLVGGKLKHSTNAIVGANSLIQLKEYQFTKTFLGVNGIDLRYGC
CCHHHHHHHHHHHCCHHHHCCCEECCCCEEECCCCEEEHHHHHHHHHHHCCCCCEEEECC
TTADPEEAAMKNLALQQSATTYMLADESKWNNVNFAKICDINEVNFIIEKLTPTHEPFQP
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCC
HTNILEAT
CCCCCCCC
>Mature Secondary Structure
MLTDERHRLILKKLNESGVVKSFDLINDLNCSESTIRRDLAQLEEEGMLTRIHGGAKKHY
CCCCHHHHHHHHHCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHCC
SFDKEPTYQEKTIKNVQHKTSIGKFAASLIEENDVIYLDAGTTTLEIIPYLPDIPLTVVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHH
NGIVHASMLATKQIPSYLVGGKLKHSTNAIVGANSLIQLKEYQFTKTFLGVNGIDLRYGC
CCHHHHHHHHHHHCCHHHHCCCEECCCCEEECCCCEEEHHHHHHHHHHHCCCCCEEEECC
TTADPEEAAMKNLALQQSATTYMLADESKWNNVNFAKICDINEVNFIIEKLTPTHEPFQP
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCC
HTNILEAT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]