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The map label for this gene is yngJ [H]

Identifier: 23098129

GI number: 23098129

Start: 711972

End: 713177

Strand: Direct

Name: yngJ [H]

Synonym: OB0674

Alternate gene names: 23098129

Gene position: 711972-713177 (Clockwise)

Preceding gene: 23098128

Following gene: 23098130

Centisome position: 19.61

GC content: 40.38

Gene sequence:

>1206_bases
ATGGAATTTAAGTACTCAGATAAAGTGAATTCTTATCAAGAAAAATTGACGTCATTTATGGAAACGTATATTTATCCGAA
TGAAAAAGTATATCAGGAGCAACTGGACCCCATGGATCGTTTTTCGACCATCCCACCTATTCTTGAAGAATTGAAACAGA
AAGCTAAAGATGAAAAACTATGGAACTTGTTTTTACCAGATAGTGAATACGGAGCGGGATTAACAAACTTGGAATATGCT
CCATTGTGTGAAGTTATGGGACGTTCTAGCCTCGCTCCAGAAGTATTTAACTGTGCTGCTCCTGATACAGGTAATATGGA
AACCATAGAAAGATATGGTACGGAAGAACAAAAAAAAGCGTGGTTAGAACCTTTATTACATGGAGAGATTCGTTCTTGCT
TTTCTATGACAGAGCCGGATGTTGCTTCATCGGATGCAACAAATATAAAGGCAAGTATTATCCGGGATGGTGACGATTAT
GTTATCAACGGAACAAAATGGTGGTCTTCTGGAGCTGGAGACCCTCGCTGCCAAATCGCTATTGTAATGGGGAAGAATGA
TCCAGCTGCCCAAAAGCATAAACAACAGTCAATGATTTTAGTTCCAATGGATACACCTGGTGTAACGATTAAACGAACAT
TACCTGTCTTTGGCTACGATCATGCACCACACGGTCACGCTGAAATTGAGTATCACAATGTGAGAGTACCTGCAACGAAT
ATGTTATTAGGCGAAGGAAGAGGATTTGAAATTGCTCAAGGAAGATTGGGGCCGGGGAGAATTCATCACTGTATGAGAAC
GATAGGGGCAGCGGAGCGTGCATTAGAACTTTTATGTAAGCGTGTTCTTGATCGGGAAACATTTGGTAAAAAATTGGCAG
AACAAGGGGTTATCCAAGAGTGGATTGCAAATGCAAGGATAAGTATCGAACAAGCACGATTATTAACGTTAAAAGCTGCT
TATATGATGGACACTGTAGGCAATAAAGAAGCAAAATCCGAAATTGCAATGATAAAAGTAATTGCTCCAAATATGGCGCT
TGATGTAATTGATAAAGCTATTCAAGTATTGGGAGCAGCGGGAGTAAGTGAAGATTTCCCGCTTGCTGCGAGTTGGGCTA
ACATACGAACGTTACGACTTGCTGATGGTCCTGATGAAGTTCATCGCAAGTCCATAGCAAAATGGGAACTGAAGAAGTAT
CAATAA

Upstream 100 bases:

>100_bases
TTGATGTTAAAGCTGTCAATCAGCATGATAAATCTGTTATTAAAGGCTCGATTAAATTTAAATTATTGAAAGATGAATAG
ATGGATTTGGGGTGTAATAG

Downstream 100 bases:

>100_bases
TCGGGAGTTGAGTGTATGCATGTTAAAGAGTTATTTAATCTAAAGGGAAAAACAGCCATCGTTACAGGTGGAGGACGTGG
ACTCGGCGAACAAATAGCTG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MEFKYSDKVNSYQEKLTSFMETYIYPNEKVYQEQLDPMDRFSTIPPILEELKQKAKDEKLWNLFLPDSEYGAGLTNLEYA
PLCEVMGRSSLAPEVFNCAAPDTGNMETIERYGTEEQKKAWLEPLLHGEIRSCFSMTEPDVASSDATNIKASIIRDGDDY
VINGTKWWSSGAGDPRCQIAIVMGKNDPAAQKHKQQSMILVPMDTPGVTIKRTLPVFGYDHAPHGHAEIEYHNVRVPATN
MLLGEGRGFEIAQGRLGPGRIHHCMRTIGAAERALELLCKRVLDRETFGKKLAEQGVIQEWIANARISIEQARLLTLKAA
YMMDTVGNKEAKSEIAMIKVIAPNMALDVIDKAIQVLGAAGVSEDFPLAASWANIRTLRLADGPDEVHRKSIAKWELKKY
Q

Sequences:

>Translated_401_residues
MEFKYSDKVNSYQEKLTSFMETYIYPNEKVYQEQLDPMDRFSTIPPILEELKQKAKDEKLWNLFLPDSEYGAGLTNLEYA
PLCEVMGRSSLAPEVFNCAAPDTGNMETIERYGTEEQKKAWLEPLLHGEIRSCFSMTEPDVASSDATNIKASIIRDGDDY
VINGTKWWSSGAGDPRCQIAIVMGKNDPAAQKHKQQSMILVPMDTPGVTIKRTLPVFGYDHAPHGHAEIEYHNVRVPATN
MLLGEGRGFEIAQGRLGPGRIHHCMRTIGAAERALELLCKRVLDRETFGKKLAEQGVIQEWIANARISIEQARLLTLKAA
YMMDTVGNKEAKSEIAMIKVIAPNMALDVIDKAIQVLGAAGVSEDFPLAASWANIRTLRLADGPDEVHRKSIAKWELKKY
Q
>Mature_401_residues
MEFKYSDKVNSYQEKLTSFMETYIYPNEKVYQEQLDPMDRFSTIPPILEELKQKAKDEKLWNLFLPDSEYGAGLTNLEYA
PLCEVMGRSSLAPEVFNCAAPDTGNMETIERYGTEEQKKAWLEPLLHGEIRSCFSMTEPDVASSDATNIKASIIRDGDDY
VINGTKWWSSGAGDPRCQIAIVMGKNDPAAQKHKQQSMILVPMDTPGVTIKRTLPVFGYDHAPHGHAEIEYHNVRVPATN
MLLGEGRGFEIAQGRLGPGRIHHCMRTIGAAERALELLCKRVLDRETFGKKLAEQGVIQEWIANARISIEQARLLTLKAA
YMMDTVGNKEAKSEIAMIKVIAPNMALDVIDKAIQVLGAAGVSEDFPLAASWANIRTLRLADGPDEVHRKSIAKWELKKY
Q

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=59.7989949748744, Blast_Score=481, Evalue=1e-136,
Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=59.7989949748744, Blast_Score=480, Evalue=1e-136,
Organism=Homo sapiens, GI38505218, Length=390, Percent_Identity=59.2307692307692, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=31.8435754189944, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=29.1005291005291, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI4557231, Length=409, Percent_Identity=26.161369193154, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI187960098, Length=409, Percent_Identity=26.161369193154, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4501859, Length=361, Percent_Identity=29.0858725761773, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI76496475, Length=408, Percent_Identity=27.2058823529412, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4557235, Length=408, Percent_Identity=27.2058823529412, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI7656849, Length=391, Percent_Identity=25.5754475703325, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI226958412, Length=393, Percent_Identity=24.9363867684478, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=325, Percent_Identity=25.5384615384615, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=24.468085106383, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4503943, Length=287, Percent_Identity=25.7839721254355, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7669494, Length=265, Percent_Identity=26.7924528301887, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081958, Length=314, Percent_Identity=26.7515923566879, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786223, Length=364, Percent_Identity=25.5494505494505, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=363, Percent_Identity=60.0550964187328, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17534899, Length=405, Percent_Identity=27.9012345679012, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=406, Percent_Identity=25.3694581280788, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17506239, Length=393, Percent_Identity=27.4809160305344, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=26.8229166666667, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=26.7379679144385, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=29.3650793650794, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=285, Percent_Identity=25.9649122807018, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=400, Percent_Identity=23.5, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=293, Percent_Identity=25.2559726962457, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=347, Percent_Identity=22.7665706051873, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=287, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=325, Percent_Identity=28.3076923076923, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=285, Percent_Identity=27.0175438596491, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=286, Percent_Identity=25.1748251748252, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=30.3571428571429, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24646207, Length=332, Percent_Identity=31.6265060240964, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363737, Length=409, Percent_Identity=27.8728606356968, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24660351, Length=347, Percent_Identity=27.9538904899135, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24666513, Length=290, Percent_Identity=28.9655172413793, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920834, Length=286, Percent_Identity=25.1748251748252, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44904; Mature: 44904

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKYSDKVNSYQEKLTSFMETYIYPNEKVYQEQLDPMDRFSTIPPILEELKQKAKDEKL
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHH
WNLFLPDSEYGAGLTNLEYAPLCEVMGRSSLAPEVFNCAAPDTGNMETIERYGTEEQKKA
EEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHCCHHHHHH
WLEPLLHGEIRSCFSMTEPDVASSDATNIKASIIRDGDDYVINGTKWWSSGAGDPRCQIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCEECCCCCCCCCEEEE
IVMGKNDPAAQKHKQQSMILVPMDTPGVTIKRTLPVFGYDHAPHGHAEIEYHNVRVPATN
EEECCCCCHHHHHHCCCEEEEECCCCCEEEEEECCEECCCCCCCCCCEEEEEEEECCHHH
MLLGEGRGFEIAQGRLGPGRIHHCMRTIGAAERALELLCKRVLDRETFGKKLAEQGVIQE
EEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIANARISIEQARLLTLKAAYMMDTVGNKEAKSEIAMIKVIAPNMALDVIDKAIQVLGAA
HHHCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEECCCHHHHHHHHHHHHHHCC
GVSEDFPLAASWANIRTLRLADGPDEVHRKSIAKWELKKYQ
CCCCCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEFKYSDKVNSYQEKLTSFMETYIYPNEKVYQEQLDPMDRFSTIPPILEELKQKAKDEKL
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHH
WNLFLPDSEYGAGLTNLEYAPLCEVMGRSSLAPEVFNCAAPDTGNMETIERYGTEEQKKA
EEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHCCHHHHHH
WLEPLLHGEIRSCFSMTEPDVASSDATNIKASIIRDGDDYVINGTKWWSSGAGDPRCQIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCEECCCCCCCCCEEEE
IVMGKNDPAAQKHKQQSMILVPMDTPGVTIKRTLPVFGYDHAPHGHAEIEYHNVRVPATN
EEECCCCCHHHHHHCCCEEEEECCCCCEEEEEECCEECCCCCCCCCCEEEEEEEECCHHH
MLLGEGRGFEIAQGRLGPGRIHHCMRTIGAAERALELLCKRVLDRETFGKKLAEQGVIQE
EEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIANARISIEQARLLTLKAAYMMDTVGNKEAKSEIAMIKVIAPNMALDVIDKAIQVLGAA
HHHCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEECCCHHHHHHHHHHHHHHCC
GVSEDFPLAASWANIRTLRLADGPDEVHRKSIAKWELKKYQ
CCCCCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]