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The map label for this gene is mmgC [H]

Identifier: 23098125

GI number: 23098125

Start: 709112

End: 710290

Strand: Direct

Name: mmgC [H]

Synonym: OB0670

Alternate gene names: 23098125

Gene position: 709112-710290 (Clockwise)

Preceding gene: 28563913

Following gene: 23098126

Centisome position: 19.53

GC content: 40.12

Gene sequence:

>1179_bases
ATGCATTTAAGATTAACGGATGAACAAAAAATGGTACAGCAAACGATTCGCAAATTTGTAGAAAAGGAGCTTATTCCTTT
AGAGAATGATGTGCTACGAAATGAACGAGAAGGTAAACCTAGTCTTTCAAAAGAAAAAGAAGAAGAATTAGTGTTGAAAG
CTAAGAATGCAGGCTTTTGGGGAATAAATACGCCTGAAGAGTATGGTGGAGCAGATTTAGGACAAATGATGCAAGCAATA
GTTGCGATGGAAGTATCGAAAACTTTTGTCCCATTTCAATTTGGAGGATCTGCGGATAATATTTTATATTATGGCAACGA
AGAACAAAAAAATGAATACTTAATTCCTACGATTAATGGGGAGAAGAAGTCATGTTTTGCAATGACAGAACCAGGTGCTG
GGTCTGATACACAAAATATTAAAATGACGGCAGTAAAGGATGGCTCCGAATGGGTGCTTAATGGAGAAAAAACCTTTATT
ACTGGTGGGAATGAAGCAGATTTTGTTATGGTGATCGCGATTACCGATAAGGAATTACATCAGAAGACAAAAGGTAGAGA
AGGCGTTACTTGTTTTATTGCTGACCGTGATATGGGTTGGGAATCCGAATATATTCATACGATGGGGGAATGGGGACCAG
CTAGCTTGTTTTTTGAAAATGTTCGAATCCCGGAAAAGAATATTTTAGGAGAATTGCATAAAGGCTATAACCTAGGACTC
GAATGGATTGGATTTGCAAGGTGGATTGTCGGTGCTCGCGCAGTTGGGACGGCAGAACGACTATTGCAAATGGCGATTGA
TTATTCAAAAGAGCGAGAAACATTCGGTAAGCCTATTTCAGAAAGGCAAGCAATTCAATGGCAGATTGCGGATTCTGCAG
TGGAAGTAGAAGCAGCAAGATGGCTTGTTCTAAACGCAGCGTTCACTCTTGATCAAGGAGAAGATAATCGACACCTAGCA
TCTATTGCTAAATTGTATGGGGCAAATATGGGTACGAGAGTCGTTGATCGTGTTATGCAAATTCACGGCGGGATGGGTTA
TACACGTGAATTGCCAATAGAGCGCTGGTATCGGGAAGCAAGATTGTGGAGGATTTATGATGGAACGGACGAAATTCAGC
GACTCATTATATCTAGGAATCTACTAAAAGGTCATGTCAAATTAGGACAGTACGTATAG

Upstream 100 bases:

>100_bases
TTGATTCAACTACTATAAAAATTTTTAGAGTAAACATACCAACCGGTTAGTATTAAGGTCGAGCTTATAACATATAGATG
GTGAAAAGGAGAGGAAAACG

Downstream 100 bases:

>100_bases
GAGGAAAAAATGATGACAAATAGGTTTTCTGGAAAAGTAGCTTTAATTACCGGTGGTAGTAGAGGAATTGGGAAGGCTAT
TGCTTCATTATTCGCAGAAG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MHLRLTDEQKMVQQTIRKFVEKELIPLENDVLRNEREGKPSLSKEKEEELVLKAKNAGFWGINTPEEYGGADLGQMMQAI
VAMEVSKTFVPFQFGGSADNILYYGNEEQKNEYLIPTINGEKKSCFAMTEPGAGSDTQNIKMTAVKDGSEWVLNGEKTFI
TGGNEADFVMVIAITDKELHQKTKGREGVTCFIADRDMGWESEYIHTMGEWGPASLFFENVRIPEKNILGELHKGYNLGL
EWIGFARWIVGARAVGTAERLLQMAIDYSKERETFGKPISERQAIQWQIADSAVEVEAARWLVLNAAFTLDQGEDNRHLA
SIAKLYGANMGTRVVDRVMQIHGGMGYTRELPIERWYREARLWRIYDGTDEIQRLIISRNLLKGHVKLGQYV

Sequences:

>Translated_392_residues
MHLRLTDEQKMVQQTIRKFVEKELIPLENDVLRNEREGKPSLSKEKEEELVLKAKNAGFWGINTPEEYGGADLGQMMQAI
VAMEVSKTFVPFQFGGSADNILYYGNEEQKNEYLIPTINGEKKSCFAMTEPGAGSDTQNIKMTAVKDGSEWVLNGEKTFI
TGGNEADFVMVIAITDKELHQKTKGREGVTCFIADRDMGWESEYIHTMGEWGPASLFFENVRIPEKNILGELHKGYNLGL
EWIGFARWIVGARAVGTAERLLQMAIDYSKERETFGKPISERQAIQWQIADSAVEVEAARWLVLNAAFTLDQGEDNRHLA
SIAKLYGANMGTRVVDRVMQIHGGMGYTRELPIERWYREARLWRIYDGTDEIQRLIISRNLLKGHVKLGQYV
>Mature_392_residues
MHLRLTDEQKMVQQTIRKFVEKELIPLENDVLRNEREGKPSLSKEKEEELVLKAKNAGFWGINTPEEYGGADLGQMMQAI
VAMEVSKTFVPFQFGGSADNILYYGNEEQKNEYLIPTINGEKKSCFAMTEPGAGSDTQNIKMTAVKDGSEWVLNGEKTFI
TGGNEADFVMVIAITDKELHQKTKGREGVTCFIADRDMGWESEYIHTMGEWGPASLFFENVRIPEKNILGELHKGYNLGL
EWIGFARWIVGARAVGTAERLLQMAIDYSKERETFGKPISERQAIQWQIADSAVEVEAARWLVLNAAFTLDQGEDNRHLA
SIAKLYGANMGTRVVDRVMQIHGGMGYTRELPIERWYREARLWRIYDGTDEIQRLIISRNLLKGHVKLGQYV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=394, Percent_Identity=35.0253807106599, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4501859, Length=387, Percent_Identity=31.5245478036176, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI187960098, Length=391, Percent_Identity=31.9693094629156, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI4557231, Length=391, Percent_Identity=31.9693094629156, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI226958412, Length=385, Percent_Identity=32.4675324675325, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=33.9080459770115, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=31.1855670103093, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI7656849, Length=397, Percent_Identity=26.7002518891688, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI21361497, Length=345, Percent_Identity=32.1739130434783, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI4557235, Length=393, Percent_Identity=29.7709923664122, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI76496475, Length=393, Percent_Identity=29.7709923664122, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=28.7841191066998, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=28.7841191066998, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI38505218, Length=400, Percent_Identity=28.25, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4503943, Length=387, Percent_Identity=25.3229974160207, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=25.207756232687, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=397, Percent_Identity=30.4785894206549, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786223, Length=395, Percent_Identity=28.6075949367089, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87081702, Length=371, Percent_Identity=23.989218328841, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=398, Percent_Identity=35.1758793969849, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17569725, Length=394, Percent_Identity=32.741116751269, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=387, Percent_Identity=32.8165374677003, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17570075, Length=400, Percent_Identity=30, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=392, Percent_Identity=32.1428571428571, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17506239, Length=385, Percent_Identity=32.4675324675325, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17533517, Length=393, Percent_Identity=27.4809160305344, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=334, Percent_Identity=30.2395209580838, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=391, Percent_Identity=30.1790281329923, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=388, Percent_Identity=27.319587628866, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=308, Percent_Identity=33.4415584415584, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17562446, Length=397, Percent_Identity=29.9748110831234, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=287, Percent_Identity=31.3588850174216, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=31.4285714285714, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=33.1914893617021, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=390, Percent_Identity=25.6410256410256, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=338, Percent_Identity=28.9940828402367, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=166, Percent_Identity=30.1204819277108, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=33.8461538461538, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=34.7150259067358, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24646207, Length=388, Percent_Identity=32.2164948453608, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=33.5038363171356, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI21355753, Length=391, Percent_Identity=31.4578005115089, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281363737, Length=390, Percent_Identity=31.2820512820513, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19920834, Length=392, Percent_Identity=25.2551020408163, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44522; Mature: 44522

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLRLTDEQKMVQQTIRKFVEKELIPLENDVLRNEREGKPSLSKEKEEELVLKAKNAGFW
CCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHEEEEECCCCCC
GINTPEEYGGADLGQMMQAIVAMEVSKTFVPFQFGGSADNILYYGNEEQKNEYLIPTING
CCCCCHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCEEEEEECC
EKKSCFAMTEPGAGSDTQNIKMTAVKDGSEWVLNGEKTFITGGNEADFVMVIAITDKELH
CCCCEEEEECCCCCCCCCCEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCHHHH
QKTKGREGVTCFIADRDMGWESEYIHTMGEWGPASLFFENVRIPEKNILGELHKGYNLGL
HHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCH
EWIGFARWIVGARAVGTAERLLQMAIDYSKERETFGKPISERQAIQWQIADSAVEVEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCEEHHHHE
WLVLNAAFTLDQGEDNRHLASIAKLYGANMGTRVVDRVMQIHGGMGYTRELPIERWYREA
EEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
RLWRIYDGTDEIQRLIISRNLLKGHVKLGQYV
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHLRLTDEQKMVQQTIRKFVEKELIPLENDVLRNEREGKPSLSKEKEEELVLKAKNAGFW
CCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHEEEEECCCCCC
GINTPEEYGGADLGQMMQAIVAMEVSKTFVPFQFGGSADNILYYGNEEQKNEYLIPTING
CCCCCHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCEEEEEECC
EKKSCFAMTEPGAGSDTQNIKMTAVKDGSEWVLNGEKTFITGGNEADFVMVIAITDKELH
CCCCEEEEECCCCCCCCCCEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCHHHH
QKTKGREGVTCFIADRDMGWESEYIHTMGEWGPASLFFENVRIPEKNILGELHKGYNLGL
HHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCH
EWIGFARWIVGARAVGTAERLLQMAIDYSKERETFGKPISERQAIQWQIADSAVEVEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCEEHHHHE
WLVLNAAFTLDQGEDNRHLASIAKLYGANMGTRVVDRVMQIHGGMGYTRELPIERWYREA
EEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
RLWRIYDGTDEIQRLIISRNLLKGHVKLGQYV
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]