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The map label for this gene is nprB [H]

Identifier: 23098121

GI number: 23098121

Start: 702232

End: 703818

Strand: Direct

Name: nprB [H]

Synonym: OB0666

Alternate gene names: 23098121

Gene position: 702232-703818 (Clockwise)

Preceding gene: 23098120

Following gene: 23098122

Centisome position: 19.34

GC content: 37.87

Gene sequence:

>1587_bases
TTGAAAATGAATAAACGTGTGGTTTCATCAGCACTAGCAATAGCTGTATCCATCGGGATTGGTAGTTCAATAGTTGTCGC
CGAGGATATTAACATCCAGATGAATAAAACCTATGATACTCCTTCATATATTATTGAAAACTGGAAGTCTCCTAACGGTC
TGTCAAAGAAAGAGATCGTTTTAACATATATTGAAAGTAAAGGAGAGGAATTTAAGTTAAATAGTAATCCAAATATAGAC
TTTCAAATAAATAATGTTAATGCAGATAGTGAGACGGCTACTTCCCATTTTAGAGTGAAGCAAACGTATAAGGGAATTCC
TATATATGGTGCAGATCAAACGATTAGCTTAGATGAAAATAACCATGTTACATCTTATTTTGGACAAGTTGTTACTGGTA
TGAATGAAAGTATTGTAGTAGGTAATCCAATTACAGAATCAGAAATCATCGATATTTTTAAAAGGAACCTTGAAGAAAAT
ATCGGAACTGTGGACCAATTTGATGGGAAGATTGAAGCAGATCCCTATATTTACGAGTATGAAGATGAATTTTATTTCAC
CTATTTAGTTACTGCATCTACAACTAACCCAGAAGTTGGTTTTTGGCATTATTTTATAGATGCAAAGAGTGGGGAAGTTA
TTGATCATTTTAATGCATCCCAAGATGTAACCGCATTCGGTACAGGTGTATTTGGCGAAAGACAAAAGTTTGAGGCACAA
CAGTACGAAGATATGTTTCGACTATTTGATGTAACACGTGGCGATGGCGTTGTTACTTACGACAATACAACAGGAACCAA
CGTTGATGTACTAAGTTTTAACAAAATGTTTTCTGATGGAGCTGCCGTAGATGCTCATGCAAATGCGCAGAAAACATATG
ATTATTTCCTAGATACGTTTGGTCGTAATTCTGTGGATGATAATGGTCAAATTCTGATTTCGGCGGTACATGTAGGAGAT
AATTGGAATAATGCATCTTGGAATGGGAGACAAATGTCGTACGGTGATGGAGATGGTATCAGATTTCACCCATTAGCCGG
TGGACTTGATGTAGCTGCCCATGAAATGTCACATGGTGTCATCCAACATACCGCAAATTTGATTTATCGGAATGAATCTG
GAGCGTTAAATGAATCCTTCGCGGATATTTTTGGAGCGATGGTAGATCGTGAGAATTGGTTAATGGGTGAGGACATTATG
GCGGATGGCACACTTGCGTTACGTTCGTTAGAAGATCCAGCAGTCCTGATTGAAAGAAGAACACAGGAACCATATCCTGA
CCATTGGGATAGAAGATATGTTGGCCCATTAGACAATGGTGGAGTTCATATTAATAGTAGTATCAACAACAAAGCTGCAT
ATTTAGTAGCTGAGGGTGGAGAACACTATGATGTGGTTGTTGAAGGAGTTGGTCGTGCTGCAACAGAACAGATTTATTAC
CGTGCGCTTGATCTATATTTGACGAGTACTTCAGATTTTAGCATGATGCGACAGGCTGCGATTCAAGCAGCAACTGATTT
ATATGGTAGTAATTCACTTCATGTAGAAGCAGTAGAACAAGCCTATAATGCAGTTGGAGTCTATTAA

Upstream 100 bases:

>100_bases
GACCAGAATGATTATCAAGGGGACAGTCTAGAATTAGAATGGATTTTTAATGCAACACAATCATCTGGTCAGGATATTTA
AAAAAAGGAGGGGAAACGAT

Downstream 100 bases:

>100_bases
TCTAATTTTAAAGACTTTTTAAAAGGGGAGTAGATGATGAGGAAGAAAGTAATGTCGTTGCTATTTACGTTTATCCTTTT
ATTTTCCACTTTTATATCAG

Product: metalloproteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKMNKRVVSSALAIAVSIGIGSSIVVAEDINIQMNKTYDTPSYIIENWKSPNGLSKKEIVLTYIESKGEEFKLNSNPNID
FQINNVNADSETATSHFRVKQTYKGIPIYGADQTISLDENNHVTSYFGQVVTGMNESIVVGNPITESEIIDIFKRNLEEN
IGTVDQFDGKIEADPYIYEYEDEFYFTYLVTASTTNPEVGFWHYFIDAKSGEVIDHFNASQDVTAFGTGVFGERQKFEAQ
QYEDMFRLFDVTRGDGVVTYDNTTGTNVDVLSFNKMFSDGAAVDAHANAQKTYDYFLDTFGRNSVDDNGQILISAVHVGD
NWNNASWNGRQMSYGDGDGIRFHPLAGGLDVAAHEMSHGVIQHTANLIYRNESGALNESFADIFGAMVDRENWLMGEDIM
ADGTLALRSLEDPAVLIERRTQEPYPDHWDRRYVGPLDNGGVHINSSINNKAAYLVAEGGEHYDVVVEGVGRAATEQIYY
RALDLYLTSTSDFSMMRQAAIQAATDLYGSNSLHVEAVEQAYNAVGVY

Sequences:

>Translated_528_residues
MKMNKRVVSSALAIAVSIGIGSSIVVAEDINIQMNKTYDTPSYIIENWKSPNGLSKKEIVLTYIESKGEEFKLNSNPNID
FQINNVNADSETATSHFRVKQTYKGIPIYGADQTISLDENNHVTSYFGQVVTGMNESIVVGNPITESEIIDIFKRNLEEN
IGTVDQFDGKIEADPYIYEYEDEFYFTYLVTASTTNPEVGFWHYFIDAKSGEVIDHFNASQDVTAFGTGVFGERQKFEAQ
QYEDMFRLFDVTRGDGVVTYDNTTGTNVDVLSFNKMFSDGAAVDAHANAQKTYDYFLDTFGRNSVDDNGQILISAVHVGD
NWNNASWNGRQMSYGDGDGIRFHPLAGGLDVAAHEMSHGVIQHTANLIYRNESGALNESFADIFGAMVDRENWLMGEDIM
ADGTLALRSLEDPAVLIERRTQEPYPDHWDRRYVGPLDNGGVHINSSINNKAAYLVAEGGEHYDVVVEGVGRAATEQIYY
RALDLYLTSTSDFSMMRQAAIQAATDLYGSNSLHVEAVEQAYNAVGVY
>Mature_528_residues
MKMNKRVVSSALAIAVSIGIGSSIVVAEDINIQMNKTYDTPSYIIENWKSPNGLSKKEIVLTYIESKGEEFKLNSNPNID
FQINNVNADSETATSHFRVKQTYKGIPIYGADQTISLDENNHVTSYFGQVVTGMNESIVVGNPITESEIIDIFKRNLEEN
IGTVDQFDGKIEADPYIYEYEDEFYFTYLVTASTTNPEVGFWHYFIDAKSGEVIDHFNASQDVTAFGTGVFGERQKFEAQ
QYEDMFRLFDVTRGDGVVTYDNTTGTNVDVLSFNKMFSDGAAVDAHANAQKTYDYFLDTFGRNSVDDNGQILISAVHVGD
NWNNASWNGRQMSYGDGDGIRFHPLAGGLDVAAHEMSHGVIQHTANLIYRNESGALNESFADIFGAMVDRENWLMGEDIM
ADGTLALRSLEDPAVLIERRTQEPYPDHWDRRYVGPLDNGGVHINSSINNKAAYLVAEGGEHYDVVVEGVGRAATEQIYY
RALDLYLTSTSDFSMMRQAAIQAATDLYGSNSLHVEAVEQAYNAVGVY

Specific function: Unknown

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: NA

Molecular weight: Translated: 58709; Mature: 58709

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNKRVVSSALAIAVSIGIGSSIVVAEDINIQMNKTYDTPSYIIENWKSPNGLSKKEIV
CCCHHHHHHHHEEEEEEECCCCEEEEEECCEEEEECCCCCHHHHHHCCCCCCCCCCCEEE
LTYIESKGEEFKLNSNPNIDFQINNVNADSETATSHFRVKQTYKGIPIYGADQTISLDEN
EEEEECCCCEEEECCCCCEEEEEECCCCCCCCCHHHEEEEHHHCCCEEECCCCEEEECCC
NHVTSYFGQVVTGMNESIVVGNPITESEIIDIFKRNLEENIGTVDQFDGKIEADPYIYEY
CCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCEECCCCEEEEE
EDEFYFTYLVTASTTNPEVGFWHYFIDAKSGEVIDHFNASQDVTAFGTGVFGERQKFEAQ
CCCEEEEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEEECCCCCCHHHHHHH
QYEDMFRLFDVTRGDGVVTYDNTTGTNVDVLSFNKMFSDGAAVDAHANAQKTYDYFLDTF
HHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHC
GRNSVDDNGQILISAVHVGDNWNNASWNGRQMSYGDGDGIRFHPLAGGLDVAAHEMSHGV
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHH
IQHTANLIYRNESGALNESFADIFGAMVDRENWLMGEDIMADGTLALRSLEDPAVLIERR
HHHHEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHC
TQEPYPDHWDRRYVGPLDNGGVHINSSINNKAAYLVAEGGEHYDVVVEGVGRAATEQIYY
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHH
RALDLYLTSTSDFSMMRQAAIQAATDLYGSNSLHVEAVEQAYNAVGVY
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MKMNKRVVSSALAIAVSIGIGSSIVVAEDINIQMNKTYDTPSYIIENWKSPNGLSKKEIV
CCCHHHHHHHHEEEEEEECCCCEEEEEECCEEEEECCCCCHHHHHHCCCCCCCCCCCEEE
LTYIESKGEEFKLNSNPNIDFQINNVNADSETATSHFRVKQTYKGIPIYGADQTISLDEN
EEEEECCCCEEEECCCCCEEEEEECCCCCCCCCHHHEEEEHHHCCCEEECCCCEEEECCC
NHVTSYFGQVVTGMNESIVVGNPITESEIIDIFKRNLEENIGTVDQFDGKIEADPYIYEY
CCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCEECCCCEEEEE
EDEFYFTYLVTASTTNPEVGFWHYFIDAKSGEVIDHFNASQDVTAFGTGVFGERQKFEAQ
CCCEEEEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEEECCCCCCHHHHHHH
QYEDMFRLFDVTRGDGVVTYDNTTGTNVDVLSFNKMFSDGAAVDAHANAQKTYDYFLDTF
HHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHC
GRNSVDDNGQILISAVHVGDNWNNASWNGRQMSYGDGDGIRFHPLAGGLDVAAHEMSHGV
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHH
IQHTANLIYRNESGALNESFADIFGAMVDRENWLMGEDIMADGTLALRSLEDPAVLIERR
HHHHEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHC
TQEPYPDHWDRRYVGPLDNGGVHINSSINNKAAYLVAEGGEHYDVVVEGVGRAATEQIYY
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHH
RALDLYLTSTSDFSMMRQAAIQAATDLYGSNSLHVEAVEQAYNAVGVY
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917867; 9025291; 9353931; 9384377 [H]