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The map label for this gene is opuE [H]

Identifier: 23098119

GI number: 23098119

Start: 699662

End: 700606

Strand: Direct

Name: opuE [H]

Synonym: OB0664

Alternate gene names: 23098119

Gene position: 699662-700606 (Clockwise)

Preceding gene: 23098118

Following gene: 23098120

Centisome position: 19.27

GC content: 37.99

Gene sequence:

>945_bases
ATGTCTGTACAAATCGGAACGTTAATCGGTGCAGTTCTTATAATCTTCTTAGCAACGATTGGTGGGCTTCGTTCAGTAGC
CCCAACAGATGCGATTAGTGCTTTCCTAGCGTTGATTGGTCTATTCCTTGCTCTTCCGATTATGTTTTCAATCGCAGGTG
GATGGGGAGAAATCACATCTAATGTACCAGAGCAACATTTAACTGCGACAAGTACACTAAGTACGGTTCAATTATTAGGA
TTTTTATTACCGTCTTTCTTTTTATTACTAGGCGACCAAAATATGTATCAGCGTCTTGCTGCGTCAAAAGGTGTAAAAAC
AAGTAAGAAAGCACAAATCTCTTGGCTTTTGGCTATACTTTTGATTACACCAACTATTTCTCTGATTGCGTTTACGTCTC
GTTCGATTTTTGATGATATCGATCCAGGTATGGCACTTATCGGAGCAACGACAATCTTACCAACTGCTGTTGGAGGGATT
TTACTTGCAGCTGCAGCCGCATTTATTGTAACAACGGGGAATTCCTATTTATTATCCGCAGCAACTAATGTAACGTATGA
CATCGTTGGAAAATACGTTAAGAAAGATGCTTCAGATAAACAATTGGTATTATATACAAAGATATTTATTGTCATTTTAG
GTGTTTTTTCATTTATTCTAGGAAACTACTTCCCAACGGTACTTGAGGTACAAATGTATACTTATACCGTTTATGGAGCC
GGACTAACACCAGCGTTATTAGCAGTATTTTTCTGGAAACGAGTGAATGCTAAAGGTGGTATCTCCTCCATGATTGCAGG
TGTAGGGACAACCTTGCTTTGGGAGCTAATTTTAGGTAAACCTTTTGAATTAAATAGTGTGATCGTTGCTATCCCAGTAG
CAGTTATCGTATTAATTGTAGTGACATTGATGACAACAGAAAAACCAGTATCAAAAAATAAATAG

Upstream 100 bases:

>100_bases
AGCTCAATTAATAGCGAGTATTATTATCATATTAGCTTTTGTCGGCATAGTCTCTTATGCCATGACAGGATTAGGTTTTG
TATTAAATGTAACGACAGGT

Downstream 100 bases:

>100_bases
ATTTGTAATAGGCCGGGCATTTATGTCCGGTTTTTCTTTTGTCCAAAAATGATGTATTTACTTAGTTATTTAGAAAAAAT
AAGTACGATAATATTTGATT

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proline symporter [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSVQIGTLIGAVLIIFLATIGGLRSVAPTDAISAFLALIGLFLALPIMFSIAGGWGEITSNVPEQHLTATSTLSTVQLLG
FLLPSFFLLLGDQNMYQRLAASKGVKTSKKAQISWLLAILLITPTISLIAFTSRSIFDDIDPGMALIGATTILPTAVGGI
LLAAAAAFIVTTGNSYLLSAATNVTYDIVGKYVKKDASDKQLVLYTKIFIVILGVFSFILGNYFPTVLEVQMYTYTVYGA
GLTPALLAVFFWKRVNAKGGISSMIAGVGTTLLWELILGKPFELNSVIVAIPVAVIVLIVVTLMTTEKPVSKNK

Sequences:

>Translated_314_residues
MSVQIGTLIGAVLIIFLATIGGLRSVAPTDAISAFLALIGLFLALPIMFSIAGGWGEITSNVPEQHLTATSTLSTVQLLG
FLLPSFFLLLGDQNMYQRLAASKGVKTSKKAQISWLLAILLITPTISLIAFTSRSIFDDIDPGMALIGATTILPTAVGGI
LLAAAAAFIVTTGNSYLLSAATNVTYDIVGKYVKKDASDKQLVLYTKIFIVILGVFSFILGNYFPTVLEVQMYTYTVYGA
GLTPALLAVFFWKRVNAKGGISSMIAGVGTTLLWELILGKPFELNSVIVAIPVAVIVLIVVTLMTTEKPVSKNK
>Mature_313_residues
SVQIGTLIGAVLIIFLATIGGLRSVAPTDAISAFLALIGLFLALPIMFSIAGGWGEITSNVPEQHLTATSTLSTVQLLGF
LLPSFFLLLGDQNMYQRLAASKGVKTSKKAQISWLLAILLITPTISLIAFTSRSIFDDIDPGMALIGATTILPTAVGGIL
LAAAAAFIVTTGNSYLLSAATNVTYDIVGKYVKKDASDKQLVLYTKIFIVILGVFSFILGNYFPTVLEVQMYTYTVYGAG
LTPALLAVFFWKRVNAKGGISSMIAGVGTTLLWELILGKPFELNSVIVAIPVAVIVLIVVTLMTTEKPVSKNK

Specific function: Catalyzes the sodium-dependent uptake of extracellular proline [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1787251, Length=298, Percent_Identity=24.1610738255034, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 33343; Mature: 33212

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQIGTLIGAVLIIFLATIGGLRSVAPTDAISAFLALIGLFLALPIMFSIAGGWGEITS
CCEEHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
NVPEQHLTATSTLSTVQLLGFLLPSFFLLLGDQNMYQRLAASKGVKTSKKAQISWLLAIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LITPTISLIAFTSRSIFDDIDPGMALIGATTILPTAVGGILLAAAAAFIVTTGNSYLLSA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
ATNVTYDIVGKYVKKDASDKQLVLYTKIFIVILGVFSFILGNYFPTVLEVQMYTYTVYGA
HCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHEEHHEEEEECC
GLTPALLAVFFWKRVNAKGGISSMIAGVGTTLLWELILGKPFELNSVIVAIPVAVIVLIV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VTLMTTEKPVSKNK
HHHHHCCCCCCCCC
>Mature Secondary Structure 
SVQIGTLIGAVLIIFLATIGGLRSVAPTDAISAFLALIGLFLALPIMFSIAGGWGEITS
CEEHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
NVPEQHLTATSTLSTVQLLGFLLPSFFLLLGDQNMYQRLAASKGVKTSKKAQISWLLAIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LITPTISLIAFTSRSIFDDIDPGMALIGATTILPTAVGGILLAAAAAFIVTTGNSYLLSA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
ATNVTYDIVGKYVKKDASDKQLVLYTKIFIVILGVFSFILGNYFPTVLEVQMYTYTVYGA
HCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHEEHHEEEEECC
GLTPALLAVFFWKRVNAKGGISSMIAGVGTTLLWELILGKPFELNSVIVAIPVAVIVLIV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VTLMTTEKPVSKNK
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377 [H]