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The map label for this gene is ptxB [H]

Identifier: 23098057

GI number: 23098057

Start: 629961

End: 630923

Strand: Reverse

Name: ptxB [H]

Synonym: OB0602

Alternate gene names: 23098057

Gene position: 630923-629961 (Counterclockwise)

Preceding gene: 23098062

Following gene: 23098056

Centisome position: 17.38

GC content: 37.49

Gene sequence:

>963_bases
ATGAAGAAATTTTACAGTTTATTAATTATTCTCGGACTTGTATTATTTTTAGCAGCGTGTGGTGGTAGCTCAGACGAAGA
TACCGGTGCTGATGATTCAAGTACGAATGATGATGAATCCAATGGAGAAGAAGCAGCTGAAGGTGAAATTCCTGAAACGC
TTGTAATGGGATTTGTTCCATCACAGGATTCTGACACAATTGCAGATACAGTAGAACCCCTAGCAGAGAGATTAGGAGAA
GAGCTAGGAATTAATGTAGAAGGACGAGTTATGACCAATTACAACGCTTTAGTAGAAGCAATGGGAGCGAATCAAGTACA
CGTTGGATTTATCCCAGCATTTGGTTATGTGCTTGCTAGTGAACAATATGATGCAGAAGTTATTTTAAAATCCATTCGAT
ATGGTTCTGGAACTTATAAAGCACAATATGTCGTGCGTTCTGATTCTGGTATTGAAAGTTTAGAAGACTTAGAGGGCAAA
GTATGGGCTTATGCAGATCAAGGGTCTACTTCAGGTTACTTATTTCCAGCTAACCAATTAATGGAGGAATTTGGTTATGA
CACAGCTGCTGAACTAGAAAGTAATTTCTTCGGCGGATCAATTGCTTCCGGTGGACATGACAACTCTGCTATTTCTGTTC
TAAATGGAGACGCAGACGTTGCTACGACATTTGATGATGTAAGAACAGAACTGGAAGAAGAATATCCAACTGTAATGGAG
GATTTATCCATTCTTGGTTACACAGACGAAATTCCAAATGACACAATTTCTGTAACAAAAGAACTACCAGATGATTTTGT
ACAACAAATAAAAGAAGCGTTCTTATCCTTTAATGATGATGAAGAGATGATTCAAATTATGAACGATGTATATAATTGGG
ACGAAATTGATGAAGCATCTGACGAAGAATACGACGTTGTTCGAGAAACATACCAGAAATTCAAAGATAATATCGAACTT
TAA

Upstream 100 bases:

>100_bases
TAAAACAAAGTTAATTTACAGAAATTGACTAGATTTTTAGTTGAAAATATTATTTAATAGAACTGTAAGATATTTCTTTA
TATTACATAGGAGGGTCAAG

Downstream 100 bases:

>100_bases
TTCAACGCATTTCAATCGACTACACTAATAAAAGTGGCTGGGACATAACAAAAAGATTTGATCAAAAGACGGATGTAATT
AGAATCCGCGTATGAAATAT

Product: alkylphosphonate ABC tranporter phosphate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKKFYSLLIILGLVLFLAACGGSSDEDTGADDSSTNDDESNGEEAAEGEIPETLVMGFVPSQDSDTIADTVEPLAERLGE
ELGINVEGRVMTNYNALVEAMGANQVHVGFIPAFGYVLASEQYDAEVILKSIRYGSGTYKAQYVVRSDSGIESLEDLEGK
VWAYADQGSTSGYLFPANQLMEEFGYDTAAELESNFFGGSIASGGHDNSAISVLNGDADVATTFDDVRTELEEEYPTVME
DLSILGYTDEIPNDTISVTKELPDDFVQQIKEAFLSFNDDEEMIQIMNDVYNWDEIDEASDEEYDVVRETYQKFKDNIEL

Sequences:

>Translated_320_residues
MKKFYSLLIILGLVLFLAACGGSSDEDTGADDSSTNDDESNGEEAAEGEIPETLVMGFVPSQDSDTIADTVEPLAERLGE
ELGINVEGRVMTNYNALVEAMGANQVHVGFIPAFGYVLASEQYDAEVILKSIRYGSGTYKAQYVVRSDSGIESLEDLEGK
VWAYADQGSTSGYLFPANQLMEEFGYDTAAELESNFFGGSIASGGHDNSAISVLNGDADVATTFDDVRTELEEEYPTVME
DLSILGYTDEIPNDTISVTKELPDDFVQQIKEAFLSFNDDEEMIQIMNDVYNWDEIDEASDEEYDVVRETYQKFKDNIEL
>Mature_320_residues
MKKFYSLLIILGLVLFLAACGGSSDEDTGADDSSTNDDESNGEEAAEGEIPETLVMGFVPSQDSDTIADTVEPLAERLGE
ELGINVEGRVMTNYNALVEAMGANQVHVGFIPAFGYVLASEQYDAEVILKSIRYGSGTYKAQYVVRSDSGIESLEDLEGK
VWAYADQGSTSGYLFPANQLMEEFGYDTAAELESNFFGGSIASGGHDNSAISVLNGDADVATTFDDVRTELEEEYPTVME
DLSILGYTDEIPNDTISVTKELPDDFVQQIKEAFLSFNDDEEMIQIMNDVYNWDEIDEASDEEYDVVRETYQKFKDNIEL

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=265, Percent_Identity=22.2641509433962, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 35191; Mature: 35191

Theoretical pI: Translated: 3.53; Mature: 3.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFYSLLIILGLVLFLAACGGSSDEDTGADDSSTNDDESNGEEAAEGEIPETLVMGFVP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCC
SQDSDTIADTVEPLAERLGEELGINVEGRVMTNYNALVEAMGANQVHVGFIPAFGYVLAS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCEEEEEEHHHHHHHHHC
EQYDAEVILKSIRYGSGTYKAQYVVRSDSGIESLEDLEGKVWAYADQGSTSGYLFPANQL
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCEEECHHHH
MEEFGYDTAAELESNFFGGSIASGGHDNSAISVLNGDADVATTFDDVRTELEEEYPTVME
HHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
DLSILGYTDEIPNDTISVTKELPDDFVQQIKEAFLSFNDDEEMIQIMNDVYNWDEIDEAS
HHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
DEEYDVVRETYQKFKDNIEL
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKFYSLLIILGLVLFLAACGGSSDEDTGADDSSTNDDESNGEEAAEGEIPETLVMGFVP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCC
SQDSDTIADTVEPLAERLGEELGINVEGRVMTNYNALVEAMGANQVHVGFIPAFGYVLAS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCEEEEEEHHHHHHHHHC
EQYDAEVILKSIRYGSGTYKAQYVVRSDSGIESLEDLEGKVWAYADQGSTSGYLFPANQL
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCEEECHHHH
MEEFGYDTAAELESNFFGGSIASGGHDNSAISVLNGDADVATTFDDVRTELEEEYPTVME
HHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
DLSILGYTDEIPNDTISVTKELPDDFVQQIKEAFLSFNDDEEMIQIMNDVYNWDEIDEAS
HHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
DEEYDVVRETYQKFKDNIEL
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]