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The map label for this gene is nprA [H]

Identifier: 23097805

GI number: 23097805

Start: 370802

End: 372088

Strand: Reverse

Name: nprA [H]

Synonym: OB0350

Alternate gene names: 23097805

Gene position: 372088-370802 (Counterclockwise)

Preceding gene: 23097809

Following gene: 23097801

Centisome position: 10.25

GC content: 31.16

Gene sequence:

>1287_bases
ATGAATAATATTGGGGATATCATTAAACTAGAACGACTAAAGCAGCAAATTAAACAAACTCAATTAGCAAAAGGTATTTG
TTCCACATCCTATTTAAGTAAAATTGAAAACAATACAACTACAGCAAGTGATGAGGTTATTAACCTCTTACTACAGAAAT
TGAATATTGAGCTTTCTGACCAAGAAAAAAATGAAGAGGCTTTTATTGAAGAAATACGCGCTATTTCTAAACGAGCTCGC
ATATATCGAGAATCTAAATTTATCGAAGAAAAAATAAATGAATTGCAATACATGAAAAATATCTACCGTAAAACGACATT
TTTAGAACTGCAATTATTAATTTTTCGATTAACACTTTTCTTTGAAGATAAAGAGCGTAGTACTTTTTATCTAGATTACT
TAGAACAAGAAAAAGAAAACTTTACACCAAACCAACAGTTTTTATTTTTACAATGCAAAGCAATTTTCCATCATACGTAT
GCAGATATTCATCAGGCATTAACGTATTTTAAAGAGGCTTTAGTAATTTCAGATGATATCGTATTAGAAGGTTGGGAGAG
AGCTGATCATCAATACATGCTTGCTATTGCATATAATTCCTGTGATGAAGTAATTAATACCATAGAATACGGGAAACTTT
CCTTAAAGTATTTTCAACGTGCCTTCATTATCAATCGAACCATTGATTGTTATCTACTAATTGGTATTGCTTATAAGAAG
GGAAATAACCTTGAAGAAGCACTTAAATCTTATGAGCTAGCTTTAAAAATGACAAATGAAACTCGAATGTTAGAAGAAGT
TGAACTCTTAAAAGGAGTAATTTATCAAAATCTCGGTTCATTAAGTTCTCATTTACAACCAGAAAAAGTCATTCCATATT
ATAAAAAAAGCTTATCCTATAAACAAAAAGCAAACAACAAACTGGTTACGATATTCTCTATCGTAATTGAATATGCAAAA
TATGAGCAATGGGATAAGGTTACTTATTGGATAGATCAGGGATTTGCCGTGATAAAAAGCGCACCGGAAGCTCATCCTAA
ATACACGCATCATTTAAAAGTGTATCAAGATCTTGCCGATTATCAATATATAACGGAAGAGGTAGGTGTCGCTGCAATTA
ATTACTTTGATGGAATACAAGACCTCAGACATTGTCTAAAATATTCCGGATGGCTTGCTAATGGATTCAAAGCAAGAGGA
AAGTATAAACTCGCTTCTATATACTTTCAAATGTCTCAAAAATATCTGTTAAAACGTATGAACATTGAATATATTGGTGA
CTTATAG

Upstream 100 bases:

>100_bases
GTTCAATTATAGTATTACCGTTAAACTAATAATAACAGACAATTCTAATTAATATACAAAAATAATCATACTATAGATAC
GGGCAAGGTGGGGGAGAAAT

Downstream 100 bases:

>100_bases
CTTGTACATAAAAAAGAGTAAACATGTGAGTGGGGGGAAGCTTTTATGCTAATACCACATGTTTACTTTTTCTACTTTAA
TCATATCATTGATAATATTA

Product: transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNNIGDIIKLERLKQQIKQTQLAKGICSTSYLSKIENNTTTASDEVINLLLQKLNIELSDQEKNEEAFIEEIRAISKRAR
IYRESKFIEEKINELQYMKNIYRKTTFLELQLLIFRLTLFFEDKERSTFYLDYLEQEKENFTPNQQFLFLQCKAIFHHTY
ADIHQALTYFKEALVISDDIVLEGWERADHQYMLAIAYNSCDEVINTIEYGKLSLKYFQRAFIINRTIDCYLLIGIAYKK
GNNLEEALKSYELALKMTNETRMLEEVELLKGVIYQNLGSLSSHLQPEKVIPYYKKSLSYKQKANNKLVTIFSIVIEYAK
YEQWDKVTYWIDQGFAVIKSAPEAHPKYTHHLKVYQDLADYQYITEEVGVAAINYFDGIQDLRHCLKYSGWLANGFKARG
KYKLASIYFQMSQKYLLKRMNIEYIGDL

Sequences:

>Translated_428_residues
MNNIGDIIKLERLKQQIKQTQLAKGICSTSYLSKIENNTTTASDEVINLLLQKLNIELSDQEKNEEAFIEEIRAISKRAR
IYRESKFIEEKINELQYMKNIYRKTTFLELQLLIFRLTLFFEDKERSTFYLDYLEQEKENFTPNQQFLFLQCKAIFHHTY
ADIHQALTYFKEALVISDDIVLEGWERADHQYMLAIAYNSCDEVINTIEYGKLSLKYFQRAFIINRTIDCYLLIGIAYKK
GNNLEEALKSYELALKMTNETRMLEEVELLKGVIYQNLGSLSSHLQPEKVIPYYKKSLSYKQKANNKLVTIFSIVIEYAK
YEQWDKVTYWIDQGFAVIKSAPEAHPKYTHHLKVYQDLADYQYITEEVGVAAINYFDGIQDLRHCLKYSGWLANGFKARG
KYKLASIYFQMSQKYLLKRMNIEYIGDL
>Mature_428_residues
MNNIGDIIKLERLKQQIKQTQLAKGICSTSYLSKIENNTTTASDEVINLLLQKLNIELSDQEKNEEAFIEEIRAISKRAR
IYRESKFIEEKINELQYMKNIYRKTTFLELQLLIFRLTLFFEDKERSTFYLDYLEQEKENFTPNQQFLFLQCKAIFHHTY
ADIHQALTYFKEALVISDDIVLEGWERADHQYMLAIAYNSCDEVINTIEYGKLSLKYFQRAFIINRTIDCYLLIGIAYKK
GNNLEEALKSYELALKMTNETRMLEEVELLKGVIYQNLGSLSSHLQPEKVIPYYKKSLSYKQKANNKLVTIFSIVIEYAK
YEQWDKVTYWIDQGFAVIKSAPEAHPKYTHHLKVYQDLADYQYITEEVGVAAINYFDGIQDLRHCLKYSGWLANGFKARG
KYKLASIYFQMSQKYLLKRMNIEYIGDL

Specific function: Activates the transcription of nprS by about five fold. May bind to the upstream region of nprS promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01381 HTH_3; PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 50496; Mature: 50496

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIGDIIKLERLKQQIKQTQLAKGICSTSYLSKIENNTTTASDEVINLLLQKLNIELSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
QEKNEEAFIEEIRAISKRARIYRESKFIEEKINELQYMKNIYRKTTFLELQLLIFRLTLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEDKERSTFYLDYLEQEKENFTPNQQFLFLQCKAIFHHTYADIHQALTYFKEALVISDDI
EECCCCCEEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VLEGWERADHQYMLAIAYNSCDEVINTIEYGKLSLKYFQRAFIINRTIDCYLLIGIAYKK
EECCCCCCCCEEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEEEECC
GNNLEEALKSYELALKMTNETRMLEEVELLKGVIYQNLGSLSSHLQPEKVIPYYKKSLSY
CCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCH
KQKANNKLVTIFSIVIEYAKYEQWDKVTYWIDQGFAVIKSAPEAHPKYTHHLKVYQDLAD
HHHCCCCHHHHHHHHHHHHHHHCHHHEEEEHHCCHHHHHCCCCCCCCHHHHHHHHHHHHH
YQYITEEVGVAAINYFDGIQDLRHCLKYSGWLANGFKARGKYKLASIYFQMSQKYLLKRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
NIEYIGDL
CCHHCCCC
>Mature Secondary Structure
MNNIGDIIKLERLKQQIKQTQLAKGICSTSYLSKIENNTTTASDEVINLLLQKLNIELSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
QEKNEEAFIEEIRAISKRARIYRESKFIEEKINELQYMKNIYRKTTFLELQLLIFRLTLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEDKERSTFYLDYLEQEKENFTPNQQFLFLQCKAIFHHTYADIHQALTYFKEALVISDDI
EECCCCCEEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VLEGWERADHQYMLAIAYNSCDEVINTIEYGKLSLKYFQRAFIINRTIDCYLLIGIAYKK
EECCCCCCCCEEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEEEECC
GNNLEEALKSYELALKMTNETRMLEEVELLKGVIYQNLGSLSSHLQPEKVIPYYKKSLSY
CCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCH
KQKANNKLVTIFSIVIEYAKYEQWDKVTYWIDQGFAVIKSAPEAHPKYTHHLKVYQDLAD
HHHCCCCHHHHHHHHHHHHHHHCHHHEEEEHHCCHHHHHCCCCCCCCHHHHHHHHHHHHH
YQYITEEVGVAAINYFDGIQDLRHCLKYSGWLANGFKARGKYKLASIYFQMSQKYLLKRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
NIEYIGDL
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2203733 [H]