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The map label for this gene is citT [C]

Identifier: 23097738

GI number: 23097738

Start: 316988

End: 318409

Strand: Direct

Name: citT [C]

Synonym: OB0283

Alternate gene names: 23097738

Gene position: 316988-318409 (Clockwise)

Preceding gene: 23097737

Following gene: 23097739

Centisome position: 8.73

GC content: 36.01

Gene sequence:

>1422_bases
ATGTCTCCGATCACTAAATATTTTAATGGCATGTCTTATCGCTCTGTATTTCTATACAGTATATTCATCATTTTATTTGT
AGCATTCTCGTTTACTAGATCGTTAGAGTACGAGGCAAAGGTTACGCTAATTATTTTTATTATTGCGATGGTATTATGGG
TAGCTACGAAGCTCCCTGCTGGATATGTAGCACTTGGATCATTATTATCGATCATTCTATTAAAAGGAGCTAGCACTAGC
TTATTATATGAATCATTTTCACTTGAAATAGTTTGGTTAATGATTGGAGCATTTATGATAGGTGAAGCGGTAAAACGTTC
TGGATTAGCTGATCGAATGATGAACTCGATCCTACATCGCTCTACAAGTTACAATGGACTTTTATTTTATGTCATGGTAG
CGCTTTTTCCATTAGCTATTTTTATTCCATCTACATCTGGGAGGGCTGCGTTAACATTGCCTGTTGTTAAGGAATTGGGT
AGACGAATTAAGGATGAGAAACAGAAGCAAACACTTGCGTTGTTTGTCCCAATCATTATTTTGATGTCAACATCAGCTAC
TGTGATTGGAGCGGGATCACATCTAATAGGTATAGAACTATTAAACCAAACAACAGGGGATTCGATTTCGTATTTTAATT
GGTTGATTTGGGGTTTGCCTTTTGCTTTGTTTATTAGCCTTGTTACCTACTTTGTAATAAAACTATATATGGTACGGCAA
GGCTCTAATCCTGTATCCACGGAAATAGTCAGTGATTCAGTTGAACATGAGAAAAAAGCTATGACAAAAAAAGAGTCGCA
AACCTTAATAATCATTGGCATTCTTGTTCTGCTTTGGTTAACAGAGGCAGTACATGGTTATGAAATTGGGTTTATTACTA
TTTTGGGGGCTATTGTTTTGATGACTCCTAAATATGGTCTGATTTCGTGGAGGCAAGGGATAAAGGCAGTATCTTGGAAT
TTGATTATATTTGTATCGGCTGCAACGGCTTTAGGGATTAACCTAGTGGAAACAGGAGTTGTTGGATGGGTTGAGGAACA
TATCTTTCAATTTATTTCAACATATTCTGGCTTCAGTCATTGGGGAATACTTTGTGTGATTCTACTCATTTCCATTACGA
GTCATTTATACGTGACCTCCCATACGACAAGAGCCATTGTATTTCTACCTGGATTTCTTATGTTGAGTACGTCGTTAGAT
TTGAATGCTACCGCAGTTTTATTTTTAAGTTTGATTGGTATGAATTATTGTGTGACTTTTCCAGTTAGCTCTAAAGCATT
GCTTGTGTATTTTGAACAGGAGGAAATGAACTTTGAAGCCAGAGATTTGATAAAGTTAAGTATGCTACTGATGCCTGTTT
ATTTTATTTCTATGTTGATATTCTATTATACGTATTGGTCATGGACTGGATTATCACTATAG

Upstream 100 bases:

>100_bases
CGATAAGACAAATACAAATAGGATACAACATTGCACAACGCAAATATAAACGGGATGTAATATGATAGGCGATACTCGAA
TAGAAAGAAGAAATGCGAGA

Downstream 100 bases:

>100_bases
AATTTTTTCGCACCGCGTTTTTAGTGGAAATATACCTTGCATAAGATCACCTTATATACAAACGATAAACAGAGGTGATT
TTTCAATGAAAAGAATTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSPITKYFNGMSYRSVFLYSIFIILFVAFSFTRSLEYEAKVTLIIFIIAMVLWVATKLPAGYVALGSLLSIILLKGASTS
LLYESFSLEIVWLMIGAFMIGEAVKRSGLADRMMNSILHRSTSYNGLLFYVMVALFPLAIFIPSTSGRAALTLPVVKELG
RRIKDEKQKQTLALFVPIIILMSTSATVIGAGSHLIGIELLNQTTGDSISYFNWLIWGLPFALFISLVTYFVIKLYMVRQ
GSNPVSTEIVSDSVEHEKKAMTKKESQTLIIIGILVLLWLTEAVHGYEIGFITILGAIVLMTPKYGLISWRQGIKAVSWN
LIIFVSAATALGINLVETGVVGWVEEHIFQFISTYSGFSHWGILCVILLISITSHLYVTSHTTRAIVFLPGFLMLSTSLD
LNATAVLFLSLIGMNYCVTFPVSSKALLVYFEQEEMNFEARDLIKLSMLLMPVYFISMLIFYYTYWSWTGLSL

Sequences:

>Translated_473_residues
MSPITKYFNGMSYRSVFLYSIFIILFVAFSFTRSLEYEAKVTLIIFIIAMVLWVATKLPAGYVALGSLLSIILLKGASTS
LLYESFSLEIVWLMIGAFMIGEAVKRSGLADRMMNSILHRSTSYNGLLFYVMVALFPLAIFIPSTSGRAALTLPVVKELG
RRIKDEKQKQTLALFVPIIILMSTSATVIGAGSHLIGIELLNQTTGDSISYFNWLIWGLPFALFISLVTYFVIKLYMVRQ
GSNPVSTEIVSDSVEHEKKAMTKKESQTLIIIGILVLLWLTEAVHGYEIGFITILGAIVLMTPKYGLISWRQGIKAVSWN
LIIFVSAATALGINLVETGVVGWVEEHIFQFISTYSGFSHWGILCVILLISITSHLYVTSHTTRAIVFLPGFLMLSTSLD
LNATAVLFLSLIGMNYCVTFPVSSKALLVYFEQEEMNFEARDLIKLSMLLMPVYFISMLIFYYTYWSWTGLSL
>Mature_472_residues
SPITKYFNGMSYRSVFLYSIFIILFVAFSFTRSLEYEAKVTLIIFIIAMVLWVATKLPAGYVALGSLLSIILLKGASTSL
LYESFSLEIVWLMIGAFMIGEAVKRSGLADRMMNSILHRSTSYNGLLFYVMVALFPLAIFIPSTSGRAALTLPVVKELGR
RIKDEKQKQTLALFVPIIILMSTSATVIGAGSHLIGIELLNQTTGDSISYFNWLIWGLPFALFISLVTYFVIKLYMVRQG
SNPVSTEIVSDSVEHEKKAMTKKESQTLIIIGILVLLWLTEAVHGYEIGFITILGAIVLMTPKYGLISWRQGIKAVSWNL
IIFVSAATALGINLVETGVVGWVEEHIFQFISTYSGFSHWGILCVILLISITSHLYVTSHTTRAIVFLPGFLMLSTSLDL
NATAVLFLSLIGMNYCVTFPVSSKALLVYFEQEEMNFEARDLIKLSMLLMPVYFISMLIFYYTYWSWTGLSL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786829, Length=392, Percent_Identity=23.9795918367347, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52909; Mature: 52778

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPITKYFNGMSYRSVFLYSIFIILFVAFSFTRSLEYEAKVTLIIFIIAMVLWVATKLPA
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
GYVALGSLLSIILLKGASTSLLYESFSLEIVWLMIGAFMIGEAVKRSGLADRMMNSILHR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
STSYNGLLFYVMVALFPLAIFIPSTSGRAALTLPVVKELGRRIKDEKQKQTLALFVPIII
CCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMSTSATVIGAGSHLIGIELLNQTTGDSISYFNWLIWGLPFALFISLVTYFVIKLYMVRQ
HHCCCCEEEECCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSNPVSTEIVSDSVEHEKKAMTKKESQTLIIIGILVLLWLTEAVHGYEIGFITILGAIVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MTPKYGLISWRQGIKAVSWNLIIFVSAATALGINLVETGVVGWVEEHIFQFISTYSGFSH
HCCCCCHHHHHHCCHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
WGILCVILLISITSHLYVTSHTTRAIVFLPGFLMLSTSLDLNATAVLFLSLIGMNYCVTF
HHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCEEEEE
PVSSKALLVYFEQEEMNFEARDLIKLSMLLMPVYFISMLIFYYTYWSWTGLSL
CCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPITKYFNGMSYRSVFLYSIFIILFVAFSFTRSLEYEAKVTLIIFIIAMVLWVATKLPA
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
GYVALGSLLSIILLKGASTSLLYESFSLEIVWLMIGAFMIGEAVKRSGLADRMMNSILHR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
STSYNGLLFYVMVALFPLAIFIPSTSGRAALTLPVVKELGRRIKDEKQKQTLALFVPIII
CCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMSTSATVIGAGSHLIGIELLNQTTGDSISYFNWLIWGLPFALFISLVTYFVIKLYMVRQ
HHCCCCEEEECCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSNPVSTEIVSDSVEHEKKAMTKKESQTLIIIGILVLLWLTEAVHGYEIGFITILGAIVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MTPKYGLISWRQGIKAVSWNLIIFVSAATALGINLVETGVVGWVEEHIFQFISTYSGFSH
HCCCCCHHHHHHCCHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
WGILCVILLISITSHLYVTSHTTRAIVFLPGFLMLSTSLDLNATAVLFLSLIGMNYCVTF
HHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCEEEEE
PVSSKALLVYFEQEEMNFEARDLIKLSMLLMPVYFISMLIFYYTYWSWTGLSL
CCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]