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The map label for this gene is bsaA [H]

Identifier: 23097718

GI number: 23097718

Start: 296223

End: 296696

Strand: Direct

Name: bsaA [H]

Synonym: OB0263

Alternate gene names: 23097718

Gene position: 296223-296696 (Clockwise)

Preceding gene: 23097717

Following gene: 28563902

Centisome position: 8.16

GC content: 34.18

Gene sequence:

>474_bases
ATGTCTATATACGAGTACCAAGTTGAAAAAAGTAATGGAGAAGAAATTTCACTATCTCAGTATCAGGACAACGTTTTATT
AATTGTTAATACAGCAACTAAGTGTGGGTTTGCAAATCAATTTGAAGGATTAGAGGAATTGCACCAAAAATATCAAGATG
AAGGGCTGCGTGTTCTCGGATTTCCAAGTAATCAATTTAACGAACAAGAACCAGTTGATGATGAAAATATGGAAGAAGCA
TGTAAGGTTAATTTTGGCGTTACATTTCCATTGTTTAAAAAGATTGATGTAAAAGGTCCTAATGCCGCCCCGTTGTTTAA
ATATTTAACAGAGGAACAAAAAGGGTTGTTAGGCAGTAATGTGAAATGGAATTTTACAAAGTTTCTTGTAGACCGAAATG
GAAATGTCGTGAAAAGATTCGCACCCAAAGATAAACCAGCAAAAATAGAAGATGACATCAAAGCACTCTTATAA

Upstream 100 bases:

>100_bases
CAACGTGTATTACTTTGATGCATCCAATGTGAATACAAGCTTTATAGTTTATATATTCGTGAAGTTACTATATTCTTAGT
ATTAGGAGGTGCATGACATT

Downstream 100 bases:

>100_bases
GCTTGGGTAAATTTAGAGCTGACTTATAAAAAATAAATGTAAAAACAGCAGTGTTTAACACTGCTGTTTTTTTATACACA
GGAAATTATAAAATGAATGT

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSIYEYQVEKSNGEEISLSQYQDNVLLIVNTATKCGFANQFEGLEELHQKYQDEGLRVLGFPSNQFNEQEPVDDENMEEA
CKVNFGVTFPLFKKIDVKGPNAAPLFKYLTEEQKGLLGSNVKWNFTKFLVDRNGNVVKRFAPKDKPAKIEDDIKALL

Sequences:

>Translated_157_residues
MSIYEYQVEKSNGEEISLSQYQDNVLLIVNTATKCGFANQFEGLEELHQKYQDEGLRVLGFPSNQFNEQEPVDDENMEEA
CKVNFGVTFPLFKKIDVKGPNAAPLFKYLTEEQKGLLGSNVKWNFTKFLVDRNGNVVKRFAPKDKPAKIEDDIKALL
>Mature_156_residues
SIYEYQVEKSNGEEISLSQYQDNVLLIVNTATKCGFANQFEGLEELHQKYQDEGLRVLGFPSNQFNEQEPVDDENMEEAC
KVNFGVTFPLFKKIDVKGPNAAPLFKYLTEEQKGLLGSNVKWNFTKFLVDRNGNVVKRFAPKDKPAKIEDDIKALL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=40, Blast_Score=126, Evalue=7e-30,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=40, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI192455698, Length=157, Percent_Identity=37.5796178343949, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI15618997, Length=155, Percent_Identity=35.4838709677419, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=37.6923076923077, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI4557629, Length=177, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=32.4175824175824, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI6006001, Length=177, Percent_Identity=30.5084745762712, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI33186887, Length=173, Percent_Identity=32.3699421965318, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788003, Length=165, Percent_Identity=41.2121212121212, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=44.5859872611465, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=157, Percent_Identity=44.5859872611465, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=36.3057324840764, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=39.7515527950311, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=35.5828220858896, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.3558282208589, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=38.1578947368421, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=50.3184713375796, Blast_Score=169, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6322228, Length=146, Percent_Identity=46.5753424657534, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=38.7096774193548, Blast_Score=118, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=46.2025316455696, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24656767, Length=158, Percent_Identity=46.2025316455696, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656777, Length=158, Percent_Identity=46.2025316455696, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=42.1383647798742, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17915; Mature: 17784

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYEYQVEKSNGEEISLSQYQDNVLLIVNTATKCGFANQFEGLEELHQKYQDEGLRVLG
CCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
FPSNQFNEQEPVDDENMEEACKVNFGVTFPLFKKIDVKGPNAAPLFKYLTEEQKGLLGSN
CCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
VKWNFTKFLVDRNGNVVKRFAPKDKPAKIEDDIKALL
CCEEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
SIYEYQVEKSNGEEISLSQYQDNVLLIVNTATKCGFANQFEGLEELHQKYQDEGLRVLG
CCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
FPSNQFNEQEPVDDENMEEACKVNFGVTFPLFKKIDVKGPNAAPLFKYLTEEQKGLLGSN
CCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
VKWNFTKFLVDRNGNVVKRFAPKDKPAKIEDDIKALL
CCEEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]