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The map label for this gene is capB [H]

Identifier: 23097656

GI number: 23097656

Start: 220743

End: 221936

Strand: Direct

Name: capB [H]

Synonym: OB0201

Alternate gene names: 23097656

Gene position: 220743-221936 (Clockwise)

Preceding gene: 23097655

Following gene: 23097657

Centisome position: 6.08

GC content: 36.6

Gene sequence:

>1194_bases
ATGCTAGAAGAATTTTTAATCATTTTGCTATTAGCTTCATTAGCTATTTTCTTTGGAGTCAAAGATAAAATGATTAATGA
TAAAAATGTTGCAAGTATACCGGTCCGTATTAATGTAAATGGAATTAGAGGTAAATCTACTGTTACTAGACTAATAACAG
GGGTTCTACAAGAAGCAGGTTATCATACTGTTGGCAAAACGACAGGAACTGATGCCAGGATGCTGTACTGGTTCGATTCC
CAAGAGGCCCCTATTCAGAGAAGACTAGAAGGTCCAAATATCGGTGAACAAAGAAAAGTCATTTCTAAAGCTTCGGATTT
AAAAGCTGATGCATTAGTAAGTGAGTGTATGGCAGTTAAACCTGATTATCAAATCGTTTTTCAAGATAAAATATTACAAG
CAAACATCGGGTTAATTGTAAATGTTTTAGAAGATCATATGGACGTATTAGGACCGACATTAAAAGAAGTTGCAGACTCA
TTTTCTGAGGCAATCCCTCATAATGGTGATTTAATTATCAATGATAGTCCCTATGTACCTCACTTTAGACAGATGGCCAA
ACAACGAAATACAAAGGTGCATGTATGTGATACATCTATTATCTCGGAGGATTTTCTTAAAAAATTTGAGTATATGGTAT
TCCCAGAAAACGCAGCATTAGCAATTGCTGTGGCAGATGTTCTTGGTATTGATCATGAAACGGCTTATAGAGGAATGTTA
AAGGCATGGCCAGATCCAGGTGCTATGCAGATTATTCCAATAGGTGATAAGAATAAACCTAGTTTCTTAGTAAATGGATT
TAGTGCGAACGATCCAATGTCTACACTCAATATTTGGGAGCGTGTGAAGCAACTAAGTTATCCTACAGATGATCCCGTTG
TTATCATGAATACCCGCTCGGATCGTTTAAATCGTACGGAACAATTTATCAAACAAGTGCTACCAAATATACAGGCAGAA
ACATTAGTTGTAATGGGGGATAGTACGGGACTTATTGTAGAGGAGTATAAAAAAGGAACATTTCCTGTTAAGAACCTTTT
AGATCTAGAAAAGACAAGCACCGAAGAAATTGTACGGGTACTTCAGCCATACTTATCAGACAAGACGATCTATGGTATTG
GAAATATCCATGGCGGGGCTGATGAATTAGTAACTCGTCTAGAACAAATGAAAATCGTAAAAGAATCTGCTTAG

Upstream 100 bases:

>100_bases
AAATGGCGTTTTTAAAAGGTGCTTATATCAACTTTGTTTAGAAAAAGAGCCGGAGTGGAGGACAAAAGAAAACAATTTAA
AATGATATAGAGGTGAAAAC

Downstream 100 bases:

>100_bases
AGAAAGGAATTGAAAAATGTTTGTATTTGATACGGGAGATGTTTATTTAGCTATAGCTGCCGGAGTAATTCTGAGCTTGT
TTTATACAGAAAGGACAGGA

Product: capsular polyglutamate biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLEEFLIILLLASLAIFFGVKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAGYHTVGKTTGTDARMLYWFDS
QEAPIQRRLEGPNIGEQRKVISKASDLKADALVSECMAVKPDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADS
FSEAIPHNGDLIINDSPYVPHFRQMAKQRNTKVHVCDTSIISEDFLKKFEYMVFPENAALAIAVADVLGIDHETAYRGML
KAWPDPGAMQIIPIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRSDRLNRTEQFIKQVLPNIQAE
TLVVMGDSTGLIVEEYKKGTFPVKNLLDLEKTSTEEIVRVLQPYLSDKTIYGIGNIHGGADELVTRLEQMKIVKESA

Sequences:

>Translated_397_residues
MLEEFLIILLLASLAIFFGVKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAGYHTVGKTTGTDARMLYWFDS
QEAPIQRRLEGPNIGEQRKVISKASDLKADALVSECMAVKPDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADS
FSEAIPHNGDLIINDSPYVPHFRQMAKQRNTKVHVCDTSIISEDFLKKFEYMVFPENAALAIAVADVLGIDHETAYRGML
KAWPDPGAMQIIPIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRSDRLNRTEQFIKQVLPNIQAE
TLVVMGDSTGLIVEEYKKGTFPVKNLLDLEKTSTEEIVRVLQPYLSDKTIYGIGNIHGGADELVTRLEQMKIVKESA
>Mature_397_residues
MLEEFLIILLLASLAIFFGVKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAGYHTVGKTTGTDARMLYWFDS
QEAPIQRRLEGPNIGEQRKVISKASDLKADALVSECMAVKPDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADS
FSEAIPHNGDLIINDSPYVPHFRQMAKQRNTKVHVCDTSIISEDFLKKFEYMVFPENAALAIAVADVLGIDHETAYRGML
KAWPDPGAMQIIPIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRSDRLNRTEQFIKQVLPNIQAE
TLVVMGDSTGLIVEEYKKGTFPVKNLLDLEKTSTEEIVRVLQPYLSDKTIYGIGNIHGGADELVTRLEQMKIVKESA

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapA and CapC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008337
- InterPro:   IPR013221 [H]

Pfam domain/function: PF08245 Mur_ligase_M [H]

EC number: NA

Molecular weight: Translated: 44289; Mature: 44289

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEFLIILLLASLAIFFGVKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAG
CHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCC
YHTVGKTTGTDARMLYWFDSQEAPIQRRLEGPNIGEQRKVISKASDLKADALVSECMAVK
CEECCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
PDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADSFSEAIPHNGDLIINDSPYVP
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEECCCCCCH
HFRQMAKQRNTKVHVCDTSIISEDFLKKFEYMVFPENAALAIAVADVLGIDHETAYRGML
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHEEEECCCCEEEEEEHHHHCCCHHHHHHHHH
KAWPDPGAMQIIPIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRS
HCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCC
DRLNRTEQFIKQVLPNIQAETLVVMGDSTGLIVEEYKKGTFPVKNLLDLEKTSTEEIVRV
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHH
LQPYLSDKTIYGIGNIHGGADELVTRLEQMKIVKESA
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEEFLIILLLASLAIFFGVKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAG
CHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCC
YHTVGKTTGTDARMLYWFDSQEAPIQRRLEGPNIGEQRKVISKASDLKADALVSECMAVK
CEECCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCC
PDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADSFSEAIPHNGDLIINDSPYVP
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEECCCCCCH
HFRQMAKQRNTKVHVCDTSIISEDFLKKFEYMVFPENAALAIAVADVLGIDHETAYRGML
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHEEEECCCCEEEEEEHHHHCCCHHHHHHHHH
KAWPDPGAMQIIPIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRS
HCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCC
DRLNRTEQFIKQVLPNIQAETLVVMGDSTGLIVEEYKKGTFPVKNLLDLEKTSTEEIVRV
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHH
LQPYLSDKTIYGIGNIHGGADELVTRLEQMKIVKESA
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10475962; 12004073; 2536679 [H]