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The map label for this gene is qor [C]

Identifier: 23097636

GI number: 23097636

Start: 197481

End: 198473

Strand: Direct

Name: qor [C]

Synonym: OB0181

Alternate gene names: 23097636

Gene position: 197481-198473 (Clockwise)

Preceding gene: 23097635

Following gene: 23097637

Centisome position: 5.44

GC content: 36.96

Gene sequence:

>993_bases
TTGGATGCGAAATGTATTAGATTTTATGAATTTGGTAGACCTAAAGACGTGTTAAGAGTGGAGACCAAAAGTATTGAACC
ACCAATGAATAATGAAGTTCTGGTTCGAATGCTAGCTCGCCCTATGAATCCTTCTGATTTAATACCCATTACTGGTGCTT
ATTCTCATCGGATTTCTTTACCTAATATTCCGGGGTATGAAGGAGTGGGGGTCATAGTGGATGTTGGACCATCCGTTTCC
AATGACCTTATTGGTCAACGAGTTTTACCATTACGCGGGGAAGGTACATGGCAAGAGTATGTTAAGACATCATCAGAATT
TGCAGTTGCTATCCCTGATTCGATTGATGATTTTACAGCAGCACAGATGTATATTAATCCAATTACAGCATGGGTAGTTT
GTACGGAAGTATTAAATTTAAAACCTAATGATGTTTTATTAGTTAATGCTTGTGGTTCATCAATAGGGCATATTTTTGCT
CAATTATCAAAAATACTAGGGTTTCGATTGATCGCGGTGACTAGAAATAATAAATATACAGATAGTTTACTTCATCTAGG
TTCCTCTTATGTAATAGATACTTCCAAAGTTCCACTTAAAGAAACAGTTATGGAATTAACAAATGGAGTGGGTGCAGATG
CTGCCATTGATTCTGTTGGGGGGAACGATGGAAACGAGTTAGCTTTTAGTGTCCGCCCTAATGGCAAATTTTTAACGCTT
GGTCTCTTATCTGGGGTACAAGTAAATTGGGCCGAAATTGTAAAAATGGAAAAAGTGCATGCTAATATGTTTCATTTGCG
ACATTGGAACAAAAATGTCTCAGCAGATATATGGCAAGAAACTTTTGCCCGTTTAATTCGGCTAATAGATAGGGAGAAAT
TACGTTTGATGACGGTCCATTCTAAGTATGAGCTGTCTGATATCCAAAAGGCAATTGACGCTGTTGAATTTTCCAATAAA
ACAAAAGGAAAAATATTTTTAACAACTTACTGA

Upstream 100 bases:

>100_bases
GTCTTTTTCATATTTTGTAGAAAAGTATTAAATACTGAGCAGTTGAAGTTAAGATGATATAATTAATTAATTCTGATTTA
TTTTAAGGAGAAATATAGTT

Downstream 100 bases:

>100_bases
TCTTTTTTCTTACATTTTATATATATAATAATTCCCAAAAAGTTAAAACACCTCAACCCTTAAGGTTGGGGGTTTTTACT
ATATATAAAAACAGTTCCCT

Product: nuclear receptor binding factor 1

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDAKCIRFYEFGRPKDVLRVETKSIEPPMNNEVLVRMLARPMNPSDLIPITGAYSHRISLPNIPGYEGVGVIVDVGPSVS
NDLIGQRVLPLRGEGTWQEYVKTSSEFAVAIPDSIDDFTAAQMYINPITAWVVCTEVLNLKPNDVLLVNACGSSIGHIFA
QLSKILGFRLIAVTRNNKYTDSLLHLGSSYVIDTSKVPLKETVMELTNGVGADAAIDSVGGNDGNELAFSVRPNGKFLTL
GLLSGVQVNWAEIVKMEKVHANMFHLRHWNKNVSADIWQETFARLIRLIDREKLRLMTVHSKYELSDIQKAIDAVEFSNK
TKGKIFLTTY

Sequences:

>Translated_330_residues
MDAKCIRFYEFGRPKDVLRVETKSIEPPMNNEVLVRMLARPMNPSDLIPITGAYSHRISLPNIPGYEGVGVIVDVGPSVS
NDLIGQRVLPLRGEGTWQEYVKTSSEFAVAIPDSIDDFTAAQMYINPITAWVVCTEVLNLKPNDVLLVNACGSSIGHIFA
QLSKILGFRLIAVTRNNKYTDSLLHLGSSYVIDTSKVPLKETVMELTNGVGADAAIDSVGGNDGNELAFSVRPNGKFLTL
GLLSGVQVNWAEIVKMEKVHANMFHLRHWNKNVSADIWQETFARLIRLIDREKLRLMTVHSKYELSDIQKAIDAVEFSNK
TKGKIFLTTY
>Mature_330_residues
MDAKCIRFYEFGRPKDVLRVETKSIEPPMNNEVLVRMLARPMNPSDLIPITGAYSHRISLPNIPGYEGVGVIVDVGPSVS
NDLIGQRVLPLRGEGTWQEYVKTSSEFAVAIPDSIDDFTAAQMYINPITAWVVCTEVLNLKPNDVLLVNACGSSIGHIFA
QLSKILGFRLIAVTRNNKYTDSLLHLGSSYVIDTSKVPLKETVMELTNGVGADAAIDSVGGNDGNELAFSVRPNGKFLTL
GLLSGVQVNWAEIVKMEKVHANMFHLRHWNKNVSADIWQETFARLIRLIDREKLRLMTVHSKYELSDIQKAIDAVEFSNK
TKGKIFLTTY

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=317, Percent_Identity=29.3375394321767, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI67078406, Length=284, Percent_Identity=30.9859154929577, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI18379349, Length=342, Percent_Identity=26.0233918128655, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI24308257, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=24.0853658536585, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=24.0853658536585, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI194239674, Length=216, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI13236495, Length=216, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194239676, Length=196, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI28557745, Length=220, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=329, Percent_Identity=25.2279635258359, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=324, Percent_Identity=28.3950617283951, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17556000, Length=248, Percent_Identity=28.6290322580645, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17507255, Length=163, Percent_Identity=30.0613496932515, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=318, Percent_Identity=26.1006289308176, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319500, Length=252, Percent_Identity=28.1746031746032, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550423, Length=299, Percent_Identity=25.0836120401338, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36694; Mature: 36694

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKCIRFYEFGRPKDVLRVETKSIEPPMNNEVLVRMLARPMNPSDLIPITGAYSHRISL
CCCCEEEEECCCCCHHHEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEC
PNIPGYEGVGVIVDVGPSVSNDLIGQRVLPLRGEGTWQEYVKTSSEFAVAIPDSIDDFTA
CCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCHHH
AQMYINPITAWVVCTEVLNLKPNDVLLVNACGSSIGHIFAQLSKILGFRLIAVTRNNKYT
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECCCCHH
DSLLHLGSSYVIDTSKVPLKETVMELTNGVGADAAIDSVGGNDGNELAFSVRPNGKFLTL
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEE
GLLSGVQVNWAEIVKMEKVHANMFHLRHWNKNVSADIWQETFARLIRLIDREKLRLMTVH
EECCCCEECHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
SKYELSDIQKAIDAVEFSNKTKGKIFLTTY
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure
MDAKCIRFYEFGRPKDVLRVETKSIEPPMNNEVLVRMLARPMNPSDLIPITGAYSHRISL
CCCCEEEEECCCCCHHHEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEC
PNIPGYEGVGVIVDVGPSVSNDLIGQRVLPLRGEGTWQEYVKTSSEFAVAIPDSIDDFTA
CCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCHHH
AQMYINPITAWVVCTEVLNLKPNDVLLVNACGSSIGHIFAQLSKILGFRLIAVTRNNKYT
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECCCCHH
DSLLHLGSSYVIDTSKVPLKETVMELTNGVGADAAIDSVGGNDGNELAFSVRPNGKFLTL
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCEEEE
GLLSGVQVNWAEIVKMEKVHANMFHLRHWNKNVSADIWQETFARLIRLIDREKLRLMTVH
EECCCCEECHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
SKYELSDIQKAIDAVEFSNKTKGKIFLTTY
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]