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The map label for this gene is namA [H]

Identifier: 23097483

GI number: 23097483

Start: 32258

End: 33289

Strand: Direct

Name: namA [H]

Synonym: OB0028

Alternate gene names: 23097483

Gene position: 32258-33289 (Clockwise)

Preceding gene: 23097482

Following gene: 23097484

Centisome position: 0.89

GC content: 39.63

Gene sequence:

>1032_bases
ATGACTCAATTAGATAAGCAATACAAGATAAAAGGATTATCATTAAAGAATAAAATTGTGATGGCTCCGATGTGCCAGTA
TTCTGTAGATGCTAAAGATGGGATACCAAATGATTGGCATTTTGTTCATTATGTATCACGTGCGGTTGGTGGAGCAGGAC
TCATTATTGTGGAGATGACTGATGTTGATCCTGATGGCCGGATTACGGATTATGATCTGGGATTATGGTCAGATGAACAT
GTTCCAGCATATCGTCGTATTGTTGATGAAGTTCATCGTTACGATGCGAAGATTGGAATTCAAATTGCACATGCTGGTCG
TAAAGCAGAAGATGCAGAACCTCCTGTTGCGCCATCTGCAATTCCTGTAACCGCTGAAAGTAAAGTACCTCGTGCGTTGA
CTACAGAAGAAGTGAAGCAAACTGTCAAACAGTTCCAAGATGCTGCAAAGCGTGCAGTAGAAGCTGGATTTGATACGATT
GAAATTCATGGAGCGCATGGATATTTAATACATCAATTTCATTCTCCGTTGATTAACAAACGAGAGGATCGATACGGAGA
AGATTTATCTTTATTTGGTGTAGAGGTAATACAAGCTATAAAAGAAGTAATTCCAGAAGATATGCCACTGCTCATGCGTA
TTTCAGCGATGGAGTATATGGATGAGGGATATGATCTAAATCATTCTGTAGACATTGCTAAAAAATATCAAGAAGCTGGT
GTCGATGTTTTCCATATTTCTAGTGGTGGAGAAGGACCTCCAGGAAAACGAAAACCAGCCAATCATCCAGGATATCAGAT
TCGATTTGCTCGTACGTTTAGACAAGAATTAAATGTACCTATTATTGCGGTTGGCGTATTAGAACATCCAAAAGTTGCAG
AAGCGGCACTTGGTAATGAAGATGCAGATTTAATTGCGATTGGACGTGGCATGTTGAAAGATCCATATTGGGCAATCCAT
GCGATTGAAGAAATTACAGGAATAGCGGTTCCACCTAAACAATATGAACGGGCATTTCCACGTAAAAAATAA

Upstream 100 bases:

>100_bases
GTTCTTTTTGAGTTTTATTAGATTAAGCAGATAAATTGCAATACGTACCACCGGCTCGTAAGATGTAATATAATTACATT
CCTTTAAAAGAGGTGGTTAC

Downstream 100 bases:

>100_bases
CTTTAAAAAGGTATAATGAATGGGATAGGCTATATTAGTTAATAGTATGCTAATATAGCCTTTTCAATGTTTTGAGGGAC
TCTATGTTGCTAAATAGATG

Product: NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTQLDKQYKIKGLSLKNKIVMAPMCQYSVDAKDGIPNDWHFVHYVSRAVGGAGLIIVEMTDVDPDGRITDYDLGLWSDEH
VPAYRRIVDEVHRYDAKIGIQIAHAGRKAEDAEPPVAPSAIPVTAESKVPRALTTEEVKQTVKQFQDAAKRAVEAGFDTI
EIHGAHGYLIHQFHSPLINKREDRYGEDLSLFGVEVIQAIKEVIPEDMPLLMRISAMEYMDEGYDLNHSVDIAKKYQEAG
VDVFHISSGGEGPPGKRKPANHPGYQIRFARTFRQELNVPIIAVGVLEHPKVAEAALGNEDADLIAIGRGMLKDPYWAIH
AIEEITGIAVPPKQYERAFPRKK

Sequences:

>Translated_343_residues
MTQLDKQYKIKGLSLKNKIVMAPMCQYSVDAKDGIPNDWHFVHYVSRAVGGAGLIIVEMTDVDPDGRITDYDLGLWSDEH
VPAYRRIVDEVHRYDAKIGIQIAHAGRKAEDAEPPVAPSAIPVTAESKVPRALTTEEVKQTVKQFQDAAKRAVEAGFDTI
EIHGAHGYLIHQFHSPLINKREDRYGEDLSLFGVEVIQAIKEVIPEDMPLLMRISAMEYMDEGYDLNHSVDIAKKYQEAG
VDVFHISSGGEGPPGKRKPANHPGYQIRFARTFRQELNVPIIAVGVLEHPKVAEAALGNEDADLIAIGRGMLKDPYWAIH
AIEEITGIAVPPKQYERAFPRKK
>Mature_342_residues
TQLDKQYKIKGLSLKNKIVMAPMCQYSVDAKDGIPNDWHFVHYVSRAVGGAGLIIVEMTDVDPDGRITDYDLGLWSDEHV
PAYRRIVDEVHRYDAKIGIQIAHAGRKAEDAEPPVAPSAIPVTAESKVPRALTTEEVKQTVKQFQDAAKRAVEAGFDTIE
IHGAHGYLIHQFHSPLINKREDRYGEDLSLFGVEVIQAIKEVIPEDMPLLMRISAMEYMDEGYDLNHSVDIAKKYQEAGV
DVFHISSGGEGPPGKRKPANHPGYQIRFARTFRQELNVPIIAVGVLEHPKVAEAALGNEDADLIAIGRGMLKDPYWAIHA
IEEITGIAVPPKQYERAFPRKK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=306, Percent_Identity=28.7581699346405, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787939, Length=343, Percent_Identity=29.4460641399417, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI72001454, Length=311, Percent_Identity=28.9389067524116, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=235, Percent_Identity=31.063829787234, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=310, Percent_Identity=27.741935483871, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=306, Percent_Identity=26.1437908496732, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=263, Percent_Identity=28.8973384030418, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=257, Percent_Identity=26.8482490272374, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=257, Percent_Identity=26.4591439688716, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=231, Percent_Identity=31.6017316017316, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=31.6239316239316, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38233; Mature: 38102

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLDKQYKIKGLSLKNKIVMAPMCQYSVDAKDGIPNDWHFVHYVSRAVGGAGLIIVEMT
CCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
DVDPDGRITDYDLGLWSDEHVPAYRRIVDEVHRYDAKIGIQIAHAGRKAEDAEPPVAPSA
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCHHEEEEEECCCCCCCCCCCCCCCCC
IPVTAESKVPRALTTEEVKQTVKQFQDAAKRAVEAGFDTIEIHGAHGYLIHQFHSPLINK
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCC
REDRYGEDLSLFGVEVIQAIKEVIPEDMPLLMRISAMEYMDEGYDLNHSVDIAKKYQEAG
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
VDVFHISSGGEGPPGKRKPANHPGYQIRFARTFRQELNVPIIAVGVLEHPKVAEAALGNE
CEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCC
DADLIAIGRGMLKDPYWAIHAIEEITGIAVPPKQYERAFPRKK
CCCEEEECCCHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TQLDKQYKIKGLSLKNKIVMAPMCQYSVDAKDGIPNDWHFVHYVSRAVGGAGLIIVEMT
CCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
DVDPDGRITDYDLGLWSDEHVPAYRRIVDEVHRYDAKIGIQIAHAGRKAEDAEPPVAPSA
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCHHEEEEEECCCCCCCCCCCCCCCCC
IPVTAESKVPRALTTEEVKQTVKQFQDAAKRAVEAGFDTIEIHGAHGYLIHQFHSPLINK
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCC
REDRYGEDLSLFGVEVIQAIKEVIPEDMPLLMRISAMEYMDEGYDLNHSVDIAKKYQEAG
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
VDVFHISSGGEGPPGKRKPANHPGYQIRFARTFRQELNVPIIAVGVLEHPKVAEAALGNE
CEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCC
DADLIAIGRGMLKDPYWAIHAIEEITGIAVPPKQYERAFPRKK
CCCEEEECCCHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]