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The map label for this gene is recS [H]

Identifier: 229918688

GI number: 229918688

Start: 2939307

End: 2940725

Strand: Direct

Name: recS [H]

Synonym: EAT1b_2975

Alternate gene names: 229918688

Gene position: 2939307-2940725 (Clockwise)

Preceding gene: 229918687

Following gene: 229918689

Centisome position: 97.98

GC content: 49.82

Gene sequence:

>1419_bases
TTGTATGAAGCGACATTAAAACGAGTGTTCGGGTATGAATCGTTTCGCCCTGGGCAACGCGACATCATACATGCCGTGAT
CGAAGGGCAGGATGTATTGGCCGTCATGCCGACGGGGGCGGGAAAATCGCTGACGTTCCAACTTCCTTCTTATATTAAAA
ATCAAGGGCTCACGGTGATTGTCTCGCCATTACTCTCACTCATTGAGGACCAGATGCTGCATATACGAGAACGGGGAGAG
CGTGGTGTCGCTCGTTTGACGTCGATGGAATCGGCTGAAGAGAAGCAGGACATCATCAACCATTTGAAACGTTACCGTTT
TTTATATCTTTCACCTGAACAATTGGCCGTTCCTTATGTGACGCGTGCTCTGGCGAATGTGAAAATTCAAATGCTCGTCA
TTGACGAGGCGCACTGTATCTCACAATGGGGGCATGAGTTCCGTCCTGAGTATGCGCGTTTAGGTGAGTTGCGAAAACAG
ATTGGGAGTCCCCAGTGTATGGCGGTCACGGCGACGGCGCCAGAAGGCGTGAAACAGGACATCATTGAAAAGCTGGCACT
GTTCTCACCTGAACAATTCGTCCACTCTGCCAATCGTCCGGAAATCCGATTGTTGGTTGAACGGTTGGAAAAGGAGAAGA
AACTTGAGCGATTGAAAGAGTTGATTCGAGAGATTCCAAAACCTGCAGTCGTTTACACGGCGACCCGTCGCGAGGCAGAG
GCGTTAGCCTTTGAGCTAGAGGATGCATTGTTTTACCATGGAGGCATGTCTACGGAAGACAGGCGACTCGTGCAGTCCCA
GTTTTTACGGGACGAAGTGTCGGTCATGGTATGCACGAGTGCGTTCGGGATGGGTGTGAACAAAGACAACGTCCGTTCTG
TCGTTCATTTTCAGTTGCCAGCAACAGTCGAGGCATACATGCAGGAAATCGGACGAGCGGGACGTGACGGGCAACCCGCA
TTCGCGGTCCTTCTATATGCCGATGGCGACGAACGCATCCAGCAATTTTTAATCGACGGGCAGTACCCGAAAGACGAGGA
CATGCGACTAGCCTACTTTGAACGTGAGAACGGGACGTCAATCGCGCAACTACCAAGGTTGTTACGCATGAATGAAGAAG
ACCCGAAGTTTCTCCTGCTGAAGCAATTGTTGACAGAACGTTCGCTTCAAGAAGCACTCGATTGGGTAAAGGAAAGAAAG
CGTGATCGGTATCGTCAACTCGGACAGATGATGGATTATGCCCTCATCCGGACATGCCGCCGCGATTACTTGCTTCGTTA
TTTTTCCGAACAAACGGTCGACCAAGAAGAATGCTGTGATGTTTGTGGGCCGATTCCGTTCCCTGATACACCGCAAATCG
TCCGAAAAAATGTGACAGAATGGAAAATTCGGTTGACGCAAATCTTTTCCTTTGAATAA

Upstream 100 bases:

>100_bases
CCGGATAGCTGGGCGTTGAAACCAGTATTTGAGAAAATGGGGCGTGTCAGTTATTTTCAAATTCGACTCGTCTTCGCCAG
ACTGAAACGAGGTGAGAGTT

Downstream 100 bases:

>100_bases
TATCATAGTAAAATGATAAAAAAGGTAAAGGAGGGCATACGTTGCGACATCGGAATCAGGCGGATTCTTTACGCGAGCAA
TTGGCGGACACGTTGCCGTC

Product: ATP-dependent DNA helicase, RecQ family

Products: NA

Alternate protein names: Recombination protein S [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MYEATLKRVFGYESFRPGQRDIIHAVIEGQDVLAVMPTGAGKSLTFQLPSYIKNQGLTVIVSPLLSLIEDQMLHIRERGE
RGVARLTSMESAEEKQDIINHLKRYRFLYLSPEQLAVPYVTRALANVKIQMLVIDEAHCISQWGHEFRPEYARLGELRKQ
IGSPQCMAVTATAPEGVKQDIIEKLALFSPEQFVHSANRPEIRLLVERLEKEKKLERLKELIREIPKPAVVYTATRREAE
ALAFELEDALFYHGGMSTEDRRLVQSQFLRDEVSVMVCTSAFGMGVNKDNVRSVVHFQLPATVEAYMQEIGRAGRDGQPA
FAVLLYADGDERIQQFLIDGQYPKDEDMRLAYFERENGTSIAQLPRLLRMNEEDPKFLLLKQLLTERSLQEALDWVKERK
RDRYRQLGQMMDYALIRTCRRDYLLRYFSEQTVDQEECCDVCGPIPFPDTPQIVRKNVTEWKIRLTQIFSFE

Sequences:

>Translated_472_residues
MYEATLKRVFGYESFRPGQRDIIHAVIEGQDVLAVMPTGAGKSLTFQLPSYIKNQGLTVIVSPLLSLIEDQMLHIRERGE
RGVARLTSMESAEEKQDIINHLKRYRFLYLSPEQLAVPYVTRALANVKIQMLVIDEAHCISQWGHEFRPEYARLGELRKQ
IGSPQCMAVTATAPEGVKQDIIEKLALFSPEQFVHSANRPEIRLLVERLEKEKKLERLKELIREIPKPAVVYTATRREAE
ALAFELEDALFYHGGMSTEDRRLVQSQFLRDEVSVMVCTSAFGMGVNKDNVRSVVHFQLPATVEAYMQEIGRAGRDGQPA
FAVLLYADGDERIQQFLIDGQYPKDEDMRLAYFERENGTSIAQLPRLLRMNEEDPKFLLLKQLLTERSLQEALDWVKERK
RDRYRQLGQMMDYALIRTCRRDYLLRYFSEQTVDQEECCDVCGPIPFPDTPQIVRKNVTEWKIRLTQIFSFE
>Mature_472_residues
MYEATLKRVFGYESFRPGQRDIIHAVIEGQDVLAVMPTGAGKSLTFQLPSYIKNQGLTVIVSPLLSLIEDQMLHIRERGE
RGVARLTSMESAEEKQDIINHLKRYRFLYLSPEQLAVPYVTRALANVKIQMLVIDEAHCISQWGHEFRPEYARLGELRKQ
IGSPQCMAVTATAPEGVKQDIIEKLALFSPEQFVHSANRPEIRLLVERLEKEKKLERLKELIREIPKPAVVYTATRREAE
ALAFELEDALFYHGGMSTEDRRLVQSQFLRDEVSVMVCTSAFGMGVNKDNVRSVVHFQLPATVEAYMQEIGRAGRDGQPA
FAVLLYADGDERIQQFLIDGQYPKDEDMRLAYFERENGTSIAQLPRLLRMNEEDPKFLLLKQLLTERSLQEALDWVKERK
RDRYRQLGQMMDYALIRTCRRDYLLRYFSEQTVDQEECCDVCGPIPFPDTPQIVRKNVTEWKIRLTQIFSFE

Specific function: Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with recQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI51242947, Length=371, Percent_Identity=39.3530997304582, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI51242943, Length=371, Percent_Identity=39.3530997304582, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI148612816, Length=371, Percent_Identity=39.3530997304582, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI110735439, Length=349, Percent_Identity=36.1031518624642, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI169218196, Length=347, Percent_Identity=36.3112391930836, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI4557365, Length=463, Percent_Identity=31.9654427645788, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI14591902, Length=343, Percent_Identity=33.5276967930029, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI14591904, Length=343, Percent_Identity=33.5276967930029, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI284005309, Length=363, Percent_Identity=31.404958677686, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI262118318, Length=360, Percent_Identity=25, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI216548263, Length=360, Percent_Identity=25, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI262231852, Length=360, Percent_Identity=25, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI13518015, Length=360, Percent_Identity=25, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI188035877, Length=339, Percent_Identity=23.8938053097345, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI87196351, Length=362, Percent_Identity=23.4806629834254, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI301171475, Length=362, Percent_Identity=23.4806629834254, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI301171467, Length=362, Percent_Identity=23.4806629834254, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21071032, Length=353, Percent_Identity=22.9461756373938, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38569503, Length=355, Percent_Identity=22.2535211267606, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38569505, Length=355, Percent_Identity=22.2535211267606, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI169881239, Length=361, Percent_Identity=22.9916897506925, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI13514809, Length=361, Percent_Identity=22.9916897506925, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI164664518, Length=383, Percent_Identity=22.1932114882507, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI48994977, Length=447, Percent_Identity=39.3736017897092, Blast_Score=279, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI71987993, Length=342, Percent_Identity=38.0116959064327, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71987997, Length=342, Percent_Identity=38.0116959064327, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI32564293, Length=358, Percent_Identity=34.9162011173184, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI25145561, Length=359, Percent_Identity=36.2116991643454, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17552866, Length=367, Percent_Identity=32.9700272479564, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI115533224, Length=325, Percent_Identity=23.3846153846154, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507945, Length=332, Percent_Identity=22.8915662650602, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537549, Length=352, Percent_Identity=20.4545454545455, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=456, Percent_Identity=31.140350877193, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320041, Length=367, Percent_Identity=23.1607629427793, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320224, Length=340, Percent_Identity=23.8235294117647, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321360, Length=339, Percent_Identity=23.598820058997, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324217, Length=335, Percent_Identity=22.3880597014925, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320449, Length=330, Percent_Identity=24.8484848484848, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24664226, Length=472, Percent_Identity=33.2627118644068, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI24664230, Length=468, Percent_Identity=33.1196581196581, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI62472181, Length=468, Percent_Identity=33.1196581196581, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI24646066, Length=367, Percent_Identity=35.9673024523161, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21358123, Length=354, Percent_Identity=32.2033898305085, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24644479, Length=340, Percent_Identity=22.9411764705882, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644487, Length=340, Percent_Identity=22.9411764705882, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551833, Length=340, Percent_Identity=22.9411764705882, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644485, Length=340, Percent_Identity=22.9411764705882, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281361218, Length=340, Percent_Identity=22.9411764705882, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644481, Length=340, Percent_Identity=22.9411764705882, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644483, Length=340, Percent_Identity=22.9411764705882, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574962, Length=335, Percent_Identity=22.6865671641791, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17985987, Length=368, Percent_Identity=22.0108695652174, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584399, Length=333, Percent_Identity=22.5225225225225, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17977678, Length=365, Percent_Identity=22.1917808219178, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583281, Length=385, Percent_Identity=22.0779220779221, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583279, Length=385, Percent_Identity=22.0779220779221, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR002464
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54604; Mature: 54604

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEATLKRVFGYESFRPGQRDIIHAVIEGQDVLAVMPTGAGKSLTFQLPSYIKNQGLTVI
CCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHCCCHHH
VSPLLSLIEDQMLHIRERGERGVARLTSMESAEEKQDIINHLKRYRFLYLSPEQLAVPYV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHH
TRALANVKIQMLVIDEAHCISQWGHEFRPEYARLGELRKQIGSPQCMAVTATAPEGVKQD
HHHHHCCEEEEEEECCHHHHHHHCHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IIEKLALFSPEQFVHSANRPEIRLLVERLEKEKKLERLKELIREIPKPAVVYTATRREAE
HHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
ALAFELEDALFYHGGMSTEDRRLVQSQFLRDEVSVMVCTSAFGMGVNKDNVRSVVHFQLP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHEEEEECC
ATVEAYMQEIGRAGRDGQPAFAVLLYADGDERIQQFLIDGQYPKDEDMRLAYFERENGTS
HHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
IAQLPRLLRMNEEDPKFLLLKQLLTERSLQEALDWVKERKRDRYRQLGQMMDYALIRTCR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYLLRYFSEQTVDQEECCDVCGPIPFPDTPQIVRKNVTEWKIRLTQIFSFE
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MYEATLKRVFGYESFRPGQRDIIHAVIEGQDVLAVMPTGAGKSLTFQLPSYIKNQGLTVI
CCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHCCCHHH
VSPLLSLIEDQMLHIRERGERGVARLTSMESAEEKQDIINHLKRYRFLYLSPEQLAVPYV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHH
TRALANVKIQMLVIDEAHCISQWGHEFRPEYARLGELRKQIGSPQCMAVTATAPEGVKQD
HHHHHCCEEEEEEECCHHHHHHHCHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IIEKLALFSPEQFVHSANRPEIRLLVERLEKEKKLERLKELIREIPKPAVVYTATRREAE
HHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
ALAFELEDALFYHGGMSTEDRRLVQSQFLRDEVSVMVCTSAFGMGVNKDNVRSVVHFQLP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHEEEEECC
ATVEAYMQEIGRAGRDGQPAFAVLLYADGDERIQQFLIDGQYPKDEDMRLAYFERENGTS
HHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
IAQLPRLLRMNEEDPKFLLLKQLLTERSLQEALDWVKERKRDRYRQLGQMMDYALIRTCR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYLLRYFSEQTVDQEECCDVCGPIPFPDTPQIVRKNVTEWKIRLTQIFSFE
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377; 9642195 [H]