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The map label for this gene is pyrK [H]

Identifier: 229918569

GI number: 229918569

Start: 2821793

End: 2822512

Strand: Direct

Name: pyrK [H]

Synonym: EAT1b_2856

Alternate gene names: 229918569

Gene position: 2821793-2822512 (Clockwise)

Preceding gene: 229918568

Following gene: 229918570

Centisome position: 94.06

GC content: 53.06

Gene sequence:

>720_bases
ATGAGACATGACGTGACGATTGTCAGCAATCGACAAATCGCCAAAGCGACGATGGAAATGAAAGTCCGTTGCCCTGGGGT
GGAAATCGCCCCTGGGACGTTCTTTCATATCAAGACGTCCGGTCTGTTACGTCGACCGTTATCGGTGGCGAACGTCGAGG
GGGACGAAATTACATTCTTATATAAAGTGATTGGGGAAGGGACAACTGAGCTATCGGGGAAACGCGTCGGGGACACACTA
GACGTCCTTGGTCCGCTCGGGAACGGTTTCCCCCTAGCGCAACATGGAAAGCGGGTCGTCCTGGTCGGAGGAGGAATTGG
GGTCCCACCTCTTTACTACGTCAGACGCCGACTCCATGAGATGGGGATTGAAACGATTGCAATTCTCGGGTTTGATTCAA
AAGAAAGCGTCTTTTATGAAGATGCTTTTCGTGAACTGGGGGAGACGATCATCACGACAGTAGACGGTAGTCACGGGGAG
TCTGGCTTTGTCACTGGCCCCCTCGCACGCATCGAGGCGGATGTCTTGCTCAGCTGTGGTCCGGAAGCGATGTTAAAGGC
AGTCGCCACTTCGCCCATTCCTGAACGATATCTCTCAATCGAGAATCGGATGGGTTGTGGCATCGGTGCTTGTTTTGCCT
GTGTCTGTCAAGCACCGGGGGGCTATGTGAAAGTCTGTAGTGACGGTCCGGTATTCAATGCGGAAGAGGTGCTGTTATGA

Upstream 100 bases:

>100_bases
TTACCTCGCTCGATACAGTCGAAGCGTTGTTACAAGTCATTGAAAGCCTGTCGTTCCAAACGGTCAGCATCCCGGCATTC
ACAACGTTCGGGGTGATGGT

Downstream 100 bases:

>100_bases
GATTGAATGTCGAGTTACCAGGTCTTCGTTTAAAAAACCCAATTATTCCGGCTTCCGGATGTTTCGGATTTGGAGAAGAA
TTCGCGAAACTGTATGACCT

Product: oxidoreductase FAD/NAD(P)-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRHDVTIVSNRQIAKATMEMKVRCPGVEIAPGTFFHIKTSGLLRRPLSVANVEGDEITFLYKVIGEGTTELSGKRVGDTL
DVLGPLGNGFPLAQHGKRVVLVGGGIGVPPLYYVRRRLHEMGIETIAILGFDSKESVFYEDAFRELGETIITTVDGSHGE
SGFVTGPLARIEADVLLSCGPEAMLKAVATSPIPERYLSIENRMGCGIGACFACVCQAPGGYVKVCSDGPVFNAEEVLL

Sequences:

>Translated_239_residues
MRHDVTIVSNRQIAKATMEMKVRCPGVEIAPGTFFHIKTSGLLRRPLSVANVEGDEITFLYKVIGEGTTELSGKRVGDTL
DVLGPLGNGFPLAQHGKRVVLVGGGIGVPPLYYVRRRLHEMGIETIAILGFDSKESVFYEDAFRELGETIITTVDGSHGE
SGFVTGPLARIEADVLLSCGPEAMLKAVATSPIPERYLSIENRMGCGIGACFACVCQAPGGYVKVCSDGPVFNAEEVLL
>Mature_239_residues
MRHDVTIVSNRQIAKATMEMKVRCPGVEIAPGTFFHIKTSGLLRRPLSVANVEGDEITFLYKVIGEGTTELSGKRVGDTL
DVLGPLGNGFPLAQHGKRVVLVGGGIGVPPLYYVRRRLHEMGIETIAILGFDSKESVFYEDAFRELGETIITTVDGSHGE
SGFVTGPLARIEADVLLSCGPEAMLKAVATSPIPERYLSIENRMGCGIGACFACVCQAPGGYVKVCSDGPVFNAEEVLL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 25586; Mature: 25586

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDVTIVSNRQIAKATMEMKVRCPGVEIAPGTFFHIKTSGLLRRPLSVANVEGDEITFL
CCCCEEEECCCHHHHHEEEEEEECCCEEECCCEEEEEECCCHHHCCCHHCCCCCCCEEEE
YKVIGEGTTELSGKRVGDTLDVLGPLGNGFPLAQHGKRVVLVGGGIGVPPLYYVRRRLHE
EEECCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHH
MGIETIAILGFDSKESVFYEDAFRELGETIITTVDGSHGESGFVTGPLARIEADVLLSCG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCEECCHHHHCEEEEEECC
PEAMLKAVATSPIPERYLSIENRMGCGIGACFACVCQAPGGYVKVCSDGPVFNAEEVLL
HHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCC
>Mature Secondary Structure
MRHDVTIVSNRQIAKATMEMKVRCPGVEIAPGTFFHIKTSGLLRRPLSVANVEGDEITFL
CCCCEEEECCCHHHHHEEEEEEECCCEEECCCEEEEEECCCHHHCCCHHCCCCCCCEEEE
YKVIGEGTTELSGKRVGDTLDVLGPLGNGFPLAQHGKRVVLVGGGIGVPPLYYVRRRLHE
EEECCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHH
MGIETIAILGFDSKESVFYEDAFRELGETIITTVDGSHGESGFVTGPLARIEADVLLSCG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCEECCHHHHCEEEEEECC
PEAMLKAVATSPIPERYLSIENRMGCGIGACFACVCQAPGGYVKVCSDGPVFNAEEVLL
HHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1709162; 9384377; 8759868; 10545205 [H]