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The map label for this gene is pyc [H]

Identifier: 229918518

GI number: 229918518

Start: 2770310

End: 2773744

Strand: Direct

Name: pyc [H]

Synonym: EAT1b_2805

Alternate gene names: 229918518

Gene position: 2770310-2773744 (Clockwise)

Preceding gene: 229918517

Following gene: 229918519

Centisome position: 92.35

GC content: 50.33

Gene sequence:

>3435_bases
TTGAAACCAATTAAAAAGTTACTTGTTGCAAACCGTGGGGAAATTGCCATTCGCGTATTTCGCGCGGCGACAGAGTTAGA
CATTCGAACGGTAGCCGTCTATTCACAAGAAGATAGCGGCTCATTACATCGCTTTAAAGCCGATGAGGCCTACTTGATCG
GTGTAGACAAAAAACCGATCGATGCGTACCTCGATATTGAAGACGTCATTCGCATCGCTAAGGAGTCAGGCAGTGATGCG
ATTCACCCGGGATATGGTTTCCTTTCGGAGAACATTGAACTCGCACGACGTTGCCGTGAAGAGGGCATTATCTTTGTCGG
ACCGCATGAGTCACATTTACATGCGTTCGGGGATAAGGTACGAGCACGTCAGAGTGCGATTGCTGCGGGTCTTCCTGTCA
TTCCGGGTTCGGATGGGCCGCTCACATCATATGAAGACGCGGAAGCATTTGCGAACGAGCACGGATTCCCGCTCATGGTC
AAAGCGTCGATGGGTGGCGGAGGCCGCGGAATGCGTGTCATTCGAACAGAAGCGGAAATGAAAGATTTGATTGAACGTGC
AAAATCAGAAGCGAAGCAGGCGTTCGGTTCTGACGAAGTGTACATAGAAAAACTCGTCGAACGTCCGAAACACATCGAGG
TGCAGATTCTTGGAGATGAGCACGGTCACATCATCCACTTGTTCGAACGTGACTGTTCGGTTCAACGCCGTCACCAAAAA
GTCGTCGAAGTGGCGCCGTGTGTGACCTTGTCTGATGCATCACGCCAAGCGATTTGTGATGCGGCGGTCCAACTCATGCG
TCACGTCGGCTACGTCAACGCCGGTACGGTCGAGTTCTTGGTGACCGAGGACGAGTCGTTCTACTTCATCGAGGTCAACC
CACGTATTCAAGTGGAACATACGATCACAGAGATGGTCACAGGCTTTGATATCGTTCAAACACAATTGATGATTGCGCAA
GGTGAGTCGCTCCACGGCGATATGATTCAAATGCCGAAGCAAGAAGACATTAAACTTCTCGGTTATGCGATTCAATCACG
TGTTACGTCTGAAGACCCAGGCAACAACTTCATGCCGGATACTGGGAAAATCATGGCTTACCGTTCTCCAGGCGGCTTTG
GTGTCCGACTTGACGGTGGAAATGCGTATGTCGGTGCAGAGATTTCACCGTACTACGATTCACTTCTCGTGAAATTGTCC
ACACATGGCATGACATTCGAACAAGCGGCCTCGAAGATGGTTCGAAACTTGAACGAGTTCCGGATTCGCGGAATCAAGAC
GAACATTCCGTTCTTGATTAACGTCATGAAGCACCCGAACTTTATCAATGGAGATTACAACACGTCATTCATCGATGAGA
CGCCAGAACTGTTCGTCTTCCCGAAACGAAAAGACCGTGGGACGAAACTGTTGAACTATATCGGGGACGTGACAGTGAAT
GGATTCCCGGGTGTCGGTCTGAAAGACAAGCCGATCAGCCGTTCGGTGCGAATCCCACATGACCTCCCAGCAGAAGCGAA
GCCAGGGACGAAACAAATTCTTACAGAGCTTGGACCGGACGGCCTCGCCGATTGGATCAAACGTCAACCGGAATTGTTGT
TGACGGATACGACGATGCGAGATGCCCATCAATCGTTGCTCGCGACGCGCATGCGGACACAGGACATTTTGAACATTGCC
GAACCGACAAGCAAACTCATGCCAGAATTGTTCTCGGTCGAGGCGTGGGGCGGAGCGACGTTCGACGTCGCCTACCGCTT
CTTATCCGAAGACCCATGGGTACGTCTCATGAAGCTTCGTGAGAAGATGCCGAACGTCTTGATTCAAATGTTGCTACGCG
GTGCGAATGCGGTCGGATACAAAAACTATGCAGACAACGTCATTGAGAAATTCGTACACGAAGCGGCATATGCCGGAGTC
GACGTGTTCCGAATCTTTGACAGTCTCAACAACTTAGAATCGATTCAGTTGGCAATCGATGCGACACTTCCGACTGGGAA
AGTGGCGGAGGCGGCCATCTGTTATACGGGAGACTTGTACGATGGCAACCGTCCGAAGTACCACCTTCCGTATTATATCG
ACCTTGCGAAGAAACTTGAGGCGAGTGGTGCGCATATCTTGGCAATCAAAGATATGGCCGGTCTATTGAAGCCGGAATCG
GCCTATGCACTCGTATCGGCATTGAAAGACGCCGTGGACTTACCAATTCACTTGCATACACACGATGCTTCCGGTAACGG
GATCTTCACCTATGCTCGTGCGACAGATGCCGGTGTCGATATCGTTGACGTTGCGGCGAGCTCGATGTCAGGGATGACGT
CACAGCCTTCAGGTGGAAGTTTGGTCTACGCGCTCAACCACCACGAACGTCAGCCGAAGGTCGACCCGAAACAATATGAG
ATCATCAGTGACTACTGGCAAGACGTGCGTCATAACTATGAACCGTTTGAAAGTGATATGCGTGCCCCGCATCCATCCGT
GTATGAGCACGAGATGCCGGGTGGACAATATTCAAACCTCCAACAGCAGGCGAAAGCGGTCGGGCTTGGAGACCGTTGGG
GCGAAGTCAAGGCGATGTATGCCCGAGTGAACATGTTGTTTGGGGACATTGTCAAGGTGACGCCGTCATCTAAAGTTGTC
GGTGATATGGCGCTCTTCATGGTCCAGCATAACTTGACGGAAGAAGATGTGATGACGCGCGGACACCAGTTGGACTTCCC
GGACTCGGTCGTCGAAATGATGCGTGGTGAATTGGGGACGCCTCCAGGTGGATTCCCGAAAGATGTACAACAAGTCATCT
TGAAAGGGGAAGAGCCATTAAACGTTCGTCCTGGTAAATTGATCAAGCCATATGACTTTGAATCGGCACGCCAAGAACTA
TTCGAGAAATTCGAGCGACCGGTGACGGACTTTGAACTTCTTGCCCATGCGCTTTATCCGAAAGTGTACGAAGACTATAT
CAAACATACAACGACCTACGGGGATGTATCGGTGCTCGACACGTTGACGTTCTTCTACGGATTAAACGTGGGGGAGACAA
TCCAAGTTGAAATCGAGACAGGAAAAACATTAATCATCAAGCTCGTACAAGTGAGTGCGGCGAATGAAGATGGCATCCGT
CTCGTCTCGTATGAGATGAACGGGGTACCACGTGAAATCGAGATTAAAGATGTCAATGTCAAATCGGCAACGACAAGCCG
TCCGAAAGTCGATCGTTCGAACGCCAAACAAGTCGGTGCATCGATGCCGGGGTCTGTCTTGAAAGTATTGGTCGAACCAG
GAAGTCGTGTTCACCGTGGGGAGCAGTTGCTCGTCACAGAAGCGATGAAGATGGAAACGACAATTCAAGCGGCACAAGAT
GGTGAGATTAAGGCCATCCATATTAAAGAAGGCGACACAATACAAAGTGACGACTTGTTGATTGAATTTGTATAA

Upstream 100 bases:

>100_bases
AGAAGAAATTCGGGTGAAGTCAGAAGAAAACGTTCAACGTTCATCGCTTCACGTCGTCAGGTAAGGAAACAAACAAACTT
CATTAACGGGGGGATTTCAT

Downstream 100 bases:

>100_bases
TCAAAAGAAGCATAGCGCGCTATGCTTCTTTTTTGTAGATGGGAGTGGAGATCATGAGACGAATATGTTGGTTCCGTTCA
GATTTTAGACTGACCGATAA

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1144; Mature: 1144

Protein sequence:

>1144_residues
MKPIKKLLVANRGEIAIRVFRAATELDIRTVAVYSQEDSGSLHRFKADEAYLIGVDKKPIDAYLDIEDVIRIAKESGSDA
IHPGYGFLSENIELARRCREEGIIFVGPHESHLHAFGDKVRARQSAIAAGLPVIPGSDGPLTSYEDAEAFANEHGFPLMV
KASMGGGGRGMRVIRTEAEMKDLIERAKSEAKQAFGSDEVYIEKLVERPKHIEVQILGDEHGHIIHLFERDCSVQRRHQK
VVEVAPCVTLSDASRQAICDAAVQLMRHVGYVNAGTVEFLVTEDESFYFIEVNPRIQVEHTITEMVTGFDIVQTQLMIAQ
GESLHGDMIQMPKQEDIKLLGYAIQSRVTSEDPGNNFMPDTGKIMAYRSPGGFGVRLDGGNAYVGAEISPYYDSLLVKLS
THGMTFEQAASKMVRNLNEFRIRGIKTNIPFLINVMKHPNFINGDYNTSFIDETPELFVFPKRKDRGTKLLNYIGDVTVN
GFPGVGLKDKPISRSVRIPHDLPAEAKPGTKQILTELGPDGLADWIKRQPELLLTDTTMRDAHQSLLATRMRTQDILNIA
EPTSKLMPELFSVEAWGGATFDVAYRFLSEDPWVRLMKLREKMPNVLIQMLLRGANAVGYKNYADNVIEKFVHEAAYAGV
DVFRIFDSLNNLESIQLAIDATLPTGKVAEAAICYTGDLYDGNRPKYHLPYYIDLAKKLEASGAHILAIKDMAGLLKPES
AYALVSALKDAVDLPIHLHTHDASGNGIFTYARATDAGVDIVDVAASSMSGMTSQPSGGSLVYALNHHERQPKVDPKQYE
IISDYWQDVRHNYEPFESDMRAPHPSVYEHEMPGGQYSNLQQQAKAVGLGDRWGEVKAMYARVNMLFGDIVKVTPSSKVV
GDMALFMVQHNLTEEDVMTRGHQLDFPDSVVEMMRGELGTPPGGFPKDVQQVILKGEEPLNVRPGKLIKPYDFESARQEL
FEKFERPVTDFELLAHALYPKVYEDYIKHTTTYGDVSVLDTLTFFYGLNVGETIQVEIETGKTLIIKLVQVSAANEDGIR
LVSYEMNGVPREIEIKDVNVKSATTSRPKVDRSNAKQVGASMPGSVLKVLVEPGSRVHRGEQLLVTEAMKMETTIQAAQD
GEIKAIHIKEGDTIQSDDLLIEFV

Sequences:

>Translated_1144_residues
MKPIKKLLVANRGEIAIRVFRAATELDIRTVAVYSQEDSGSLHRFKADEAYLIGVDKKPIDAYLDIEDVIRIAKESGSDA
IHPGYGFLSENIELARRCREEGIIFVGPHESHLHAFGDKVRARQSAIAAGLPVIPGSDGPLTSYEDAEAFANEHGFPLMV
KASMGGGGRGMRVIRTEAEMKDLIERAKSEAKQAFGSDEVYIEKLVERPKHIEVQILGDEHGHIIHLFERDCSVQRRHQK
VVEVAPCVTLSDASRQAICDAAVQLMRHVGYVNAGTVEFLVTEDESFYFIEVNPRIQVEHTITEMVTGFDIVQTQLMIAQ
GESLHGDMIQMPKQEDIKLLGYAIQSRVTSEDPGNNFMPDTGKIMAYRSPGGFGVRLDGGNAYVGAEISPYYDSLLVKLS
THGMTFEQAASKMVRNLNEFRIRGIKTNIPFLINVMKHPNFINGDYNTSFIDETPELFVFPKRKDRGTKLLNYIGDVTVN
GFPGVGLKDKPISRSVRIPHDLPAEAKPGTKQILTELGPDGLADWIKRQPELLLTDTTMRDAHQSLLATRMRTQDILNIA
EPTSKLMPELFSVEAWGGATFDVAYRFLSEDPWVRLMKLREKMPNVLIQMLLRGANAVGYKNYADNVIEKFVHEAAYAGV
DVFRIFDSLNNLESIQLAIDATLPTGKVAEAAICYTGDLYDGNRPKYHLPYYIDLAKKLEASGAHILAIKDMAGLLKPES
AYALVSALKDAVDLPIHLHTHDASGNGIFTYARATDAGVDIVDVAASSMSGMTSQPSGGSLVYALNHHERQPKVDPKQYE
IISDYWQDVRHNYEPFESDMRAPHPSVYEHEMPGGQYSNLQQQAKAVGLGDRWGEVKAMYARVNMLFGDIVKVTPSSKVV
GDMALFMVQHNLTEEDVMTRGHQLDFPDSVVEMMRGELGTPPGGFPKDVQQVILKGEEPLNVRPGKLIKPYDFESARQEL
FEKFERPVTDFELLAHALYPKVYEDYIKHTTTYGDVSVLDTLTFFYGLNVGETIQVEIETGKTLIIKLVQVSAANEDGIR
LVSYEMNGVPREIEIKDVNVKSATTSRPKVDRSNAKQVGASMPGSVLKVLVEPGSRVHRGEQLLVTEAMKMETTIQAAQD
GEIKAIHIKEGDTIQSDDLLIEFV
>Mature_1144_residues
MKPIKKLLVANRGEIAIRVFRAATELDIRTVAVYSQEDSGSLHRFKADEAYLIGVDKKPIDAYLDIEDVIRIAKESGSDA
IHPGYGFLSENIELARRCREEGIIFVGPHESHLHAFGDKVRARQSAIAAGLPVIPGSDGPLTSYEDAEAFANEHGFPLMV
KASMGGGGRGMRVIRTEAEMKDLIERAKSEAKQAFGSDEVYIEKLVERPKHIEVQILGDEHGHIIHLFERDCSVQRRHQK
VVEVAPCVTLSDASRQAICDAAVQLMRHVGYVNAGTVEFLVTEDESFYFIEVNPRIQVEHTITEMVTGFDIVQTQLMIAQ
GESLHGDMIQMPKQEDIKLLGYAIQSRVTSEDPGNNFMPDTGKIMAYRSPGGFGVRLDGGNAYVGAEISPYYDSLLVKLS
THGMTFEQAASKMVRNLNEFRIRGIKTNIPFLINVMKHPNFINGDYNTSFIDETPELFVFPKRKDRGTKLLNYIGDVTVN
GFPGVGLKDKPISRSVRIPHDLPAEAKPGTKQILTELGPDGLADWIKRQPELLLTDTTMRDAHQSLLATRMRTQDILNIA
EPTSKLMPELFSVEAWGGATFDVAYRFLSEDPWVRLMKLREKMPNVLIQMLLRGANAVGYKNYADNVIEKFVHEAAYAGV
DVFRIFDSLNNLESIQLAIDATLPTGKVAEAAICYTGDLYDGNRPKYHLPYYIDLAKKLEASGAHILAIKDMAGLLKPES
AYALVSALKDAVDLPIHLHTHDASGNGIFTYARATDAGVDIVDVAASSMSGMTSQPSGGSLVYALNHHERQPKVDPKQYE
IISDYWQDVRHNYEPFESDMRAPHPSVYEHEMPGGQYSNLQQQAKAVGLGDRWGEVKAMYARVNMLFGDIVKVTPSSKVV
GDMALFMVQHNLTEEDVMTRGHQLDFPDSVVEMMRGELGTPPGGFPKDVQQVILKGEEPLNVRPGKLIKPYDFESARQEL
FEKFERPVTDFELLAHALYPKVYEDYIKHTTTYGDVSVLDTLTFFYGLNVGETIQVEIETGKTLIIKLVQVSAANEDGIR
LVSYEMNGVPREIEIKDVNVKSATTSRPKVDRSNAKQVGASMPGSVLKVLVEPGSRVHRGEQLLVTEAMKMETTIQAAQD
GEIKAIHIKEGDTIQSDDLLIEFV

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1146, Percent_Identity=49.3891797556719, Blast_Score=1091, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1146, Percent_Identity=49.3891797556719, Blast_Score=1091, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1146, Percent_Identity=49.3891797556719, Blast_Score=1091, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=464, Percent_Identity=43.75, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI189095269, Length=462, Percent_Identity=42.8571428571429, Blast_Score=362, Evalue=1e-99,
Organism=Homo sapiens, GI65506442, Length=460, Percent_Identity=42.8260869565217, Blast_Score=360, Evalue=3e-99,
Organism=Homo sapiens, GI295821183, Length=461, Percent_Identity=42.9501084598698, Blast_Score=360, Evalue=4e-99,
Organism=Homo sapiens, GI134142062, Length=522, Percent_Identity=31.992337164751, Blast_Score=244, Evalue=4e-64,
Organism=Homo sapiens, GI38679960, Length=523, Percent_Identity=31.7399617590822, Blast_Score=243, Evalue=6e-64,
Organism=Homo sapiens, GI38679977, Length=523, Percent_Identity=32.1223709369025, Blast_Score=243, Evalue=7e-64,
Organism=Homo sapiens, GI38679967, Length=523, Percent_Identity=32.1223709369025, Blast_Score=243, Evalue=7e-64,
Organism=Homo sapiens, GI38679971, Length=523, Percent_Identity=32.1223709369025, Blast_Score=243, Evalue=7e-64,
Organism=Homo sapiens, GI38679974, Length=523, Percent_Identity=31.7399617590822, Blast_Score=243, Evalue=8e-64,
Organism=Homo sapiens, GI18105007, Length=342, Percent_Identity=23.3918128654971, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1789654, Length=451, Percent_Identity=45.4545454545455, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786216, Length=271, Percent_Identity=24.3542435424354, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1151, Percent_Identity=48.74022589053, Blast_Score=1093, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=463, Percent_Identity=43.8444924406048, Blast_Score=355, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI17567343, Length=468, Percent_Identity=42.5213675213675, Blast_Score=353, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI71997163, Length=517, Percent_Identity=30.174081237911, Blast_Score=234, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71997168, Length=517, Percent_Identity=30.174081237911, Blast_Score=234, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI133931226, Length=497, Percent_Identity=28.9738430583501, Blast_Score=206, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI193204318, Length=343, Percent_Identity=22.7405247813411, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1066, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1156, Percent_Identity=48.2698961937716, Blast_Score=1050, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=39.1111111111111, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6323863, Length=438, Percent_Identity=34.9315068493151, Blast_Score=231, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6324343, Length=520, Percent_Identity=31.3461538461538, Blast_Score=229, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6322331, Length=179, Percent_Identity=26.8156424581006, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1151, Percent_Identity=50.0434404865335, Blast_Score=1104, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1151, Percent_Identity=50.0434404865335, Blast_Score=1104, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1151, Percent_Identity=50.0434404865335, Blast_Score=1104, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1151, Percent_Identity=50.0434404865335, Blast_Score=1104, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1151, Percent_Identity=50.0434404865335, Blast_Score=1104, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1167, Percent_Identity=49.528706083976, Blast_Score=1100, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1167, Percent_Identity=49.528706083976, Blast_Score=1100, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1167, Percent_Identity=49.528706083976, Blast_Score=1100, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1167, Percent_Identity=49.528706083976, Blast_Score=1100, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1167, Percent_Identity=49.528706083976, Blast_Score=1100, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=470, Percent_Identity=43.1914893617021, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24651759, Length=429, Percent_Identity=41.958041958042, Blast_Score=333, Evalue=4e-91,
Organism=Drosophila melanogaster, GI161076407, Length=516, Percent_Identity=32.3643410852713, Blast_Score=245, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586460, Length=516, Percent_Identity=32.3643410852713, Blast_Score=245, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586458, Length=516, Percent_Identity=32.3643410852713, Blast_Score=245, Evalue=2e-64,
Organism=Drosophila melanogaster, GI161076409, Length=516, Percent_Identity=32.3643410852713, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24642586, Length=190, Percent_Identity=25.2631578947368, Blast_Score=68, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45555749, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127169; Mature: 127169

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIKKLLVANRGEIAIRVFRAATELDIRTVAVYSQEDSGSLHRFKADEAYLIGVDKKPI
CCHHHHHHHCCCCCEEEEEEEHHHHCCEEEEEEEECCCCCCEEEEECCCEEEEECCCCCC
DAYLDIEDVIRIAKESGSDAIHPGYGFLSENIELARRCREEGIIFVGPHESHLHAFGDKV
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHCCEEEECCCHHHHHHHHHHH
RARQSAIAAGLPVIPGSDGPLTSYEDAEAFANEHGFPLMVKASMGGGGRGMRVIRTEAEM
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCEEEEECHHHH
KDLIERAKSEAKQAFGSDEVYIEKLVERPKHIEVQILGDEHGHIIHLFERDCSVQRRHQK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCVTLSDASRQAICDAAVQLMRHVGYVNAGTVEFLVTEDESFYFIEVNPRIQVEH
HHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEEHH
TITEMVTGFDIVQTQLMIAQGESLHGDMIQMPKQEDIKLLGYAIQSRVTSEDPGNNFMPD
HHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
TGKIMAYRSPGGFGVRLDGGNAYVGAEISPYYDSLLVKLSTHGMTFEQAASKMVRNLNEF
CCCEEEEECCCCEEEEECCCCEEECCCCCHHHHHHEEEECCCCCCHHHHHHHHHHCHHHH
RIRGIKTNIPFLINVMKHPNFINGDYNTSFIDETPELFVFPKRKDRGTKLLNYIGDVTVN
EEEEEECCCCEEEEHHCCCCEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCEEC
GFPGVGLKDKPISRSVRIPHDLPAEAKPGTKQILTELGPDGLADWIKRQPELLLTDTTMR
CCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRMRTQDILNIAEPTSKLMPELFSVEAWGGATFDVAYRFLSEDPWVRLMKLR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCHHHHHHHHHCCCHHHHHHHHH
EKMPNVLIQMLLRGANAVGYKNYADNVIEKFVHEAAYAGVDVFRIFDSLNNLESIQLAID
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEE
ATLPTGKVAEAAICYTGDLYDGNRPKYHLPYYIDLAKKLEASGAHILAIKDMAGLLKPES
ECCCCCCCCCEEEEEECCCCCCCCCCEECCEEEEHHHHHCCCCCEEEEEEHHHHHCCCHH
AYALVSALKDAVDLPIHLHTHDASGNGIFTYARATDAGVDIVDVAASSMSGMTSQPSGGS
HHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
LVYALNHHERQPKVDPKQYEIISDYWQDVRHNYEPFESDMRAPHPSVYEHEMPGGQYSNL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCHHHH
QQQAKAVGLGDRWGEVKAMYARVNMLFGDIVKVTPSSKVVGDMALFMVQHNLTEEDVMTR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHC
GHQLDFPDSVVEMMRGELGTPPGGFPKDVQQVILKGEEPLNVRPGKLIKPYDFESARQEL
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
FEKFERPVTDFELLAHALYPKVYEDYIKHTTTYGDVSVLDTLTFFYGLNVGETIQVEIET
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC
GKTLIIKLVQVSAANEDGIRLVSYEMNGVPREIEIKDVNVKSATTSRPKVDRSNAKQVGA
CCEEEEEEEHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHCC
SMPGSVLKVLVEPGSRVHRGEQLLVTEAMKMETTIQAAQDGEIKAIHIKEGDTIQSDDLL
CCCHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEE
IEFV
EEEC
>Mature Secondary Structure
MKPIKKLLVANRGEIAIRVFRAATELDIRTVAVYSQEDSGSLHRFKADEAYLIGVDKKPI
CCHHHHHHHCCCCCEEEEEEEHHHHCCEEEEEEEECCCCCCEEEEECCCEEEEECCCCCC
DAYLDIEDVIRIAKESGSDAIHPGYGFLSENIELARRCREEGIIFVGPHESHLHAFGDKV
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHCCEEEECCCHHHHHHHHHHH
RARQSAIAAGLPVIPGSDGPLTSYEDAEAFANEHGFPLMVKASMGGGGRGMRVIRTEAEM
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCEEEEECHHHH
KDLIERAKSEAKQAFGSDEVYIEKLVERPKHIEVQILGDEHGHIIHLFERDCSVQRRHQK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCVTLSDASRQAICDAAVQLMRHVGYVNAGTVEFLVTEDESFYFIEVNPRIQVEH
HHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEEHH
TITEMVTGFDIVQTQLMIAQGESLHGDMIQMPKQEDIKLLGYAIQSRVTSEDPGNNFMPD
HHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
TGKIMAYRSPGGFGVRLDGGNAYVGAEISPYYDSLLVKLSTHGMTFEQAASKMVRNLNEF
CCCEEEEECCCCEEEEECCCCEEECCCCCHHHHHHEEEECCCCCCHHHHHHHHHHCHHHH
RIRGIKTNIPFLINVMKHPNFINGDYNTSFIDETPELFVFPKRKDRGTKLLNYIGDVTVN
EEEEEECCCCEEEEHHCCCCEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCEEC
GFPGVGLKDKPISRSVRIPHDLPAEAKPGTKQILTELGPDGLADWIKRQPELLLTDTTMR
CCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRMRTQDILNIAEPTSKLMPELFSVEAWGGATFDVAYRFLSEDPWVRLMKLR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCHHHHHHHHHCCCHHHHHHHHH
EKMPNVLIQMLLRGANAVGYKNYADNVIEKFVHEAAYAGVDVFRIFDSLNNLESIQLAID
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEE
ATLPTGKVAEAAICYTGDLYDGNRPKYHLPYYIDLAKKLEASGAHILAIKDMAGLLKPES
ECCCCCCCCCEEEEEECCCCCCCCCCEECCEEEEHHHHHCCCCCEEEEEEHHHHHCCCHH
AYALVSALKDAVDLPIHLHTHDASGNGIFTYARATDAGVDIVDVAASSMSGMTSQPSGGS
HHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
LVYALNHHERQPKVDPKQYEIISDYWQDVRHNYEPFESDMRAPHPSVYEHEMPGGQYSNL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCHHHH
QQQAKAVGLGDRWGEVKAMYARVNMLFGDIVKVTPSSKVVGDMALFMVQHNLTEEDVMTR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHC
GHQLDFPDSVVEMMRGELGTPPGGFPKDVQQVILKGEEPLNVRPGKLIKPYDFESARQEL
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
FEKFERPVTDFELLAHALYPKVYEDYIKHTTTYGDVSVLDTLTFFYGLNVGETIQVEIET
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEC
GKTLIIKLVQVSAANEDGIRLVSYEMNGVPREIEIKDVNVKSATTSRPKVDRSNAKQVGA
CCEEEEEEEHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHCC
SMPGSVLKVLVEPGSRVHRGEQLLVTEAMKMETTIQAAQDGEIKAIHIKEGDTIQSDDLL
CCCHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEE
IEFV
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]