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The map label for this gene is speA [H]

Identifier: 229918504

GI number: 229918504

Start: 2758217

End: 2759698

Strand: Reverse

Name: speA [H]

Synonym: EAT1b_2791

Alternate gene names: 229918504

Gene position: 2759698-2758217 (Counterclockwise)

Preceding gene: 229918508

Following gene: 229918502

Centisome position: 91.99

GC content: 50.13

Gene sequence:

>1482_bases
TTGAAATTAAAAGGTGCTACTCAGCTCGAAACGCCACTATTTGACACGTTGCTTGAACATGTCGACTCAAACCCGATTGC
GTTCCATATTCCTGGTCATAAAAGCGGAAAAGGGATGGACCCGGAGTTTCGTGACTTTATTGGTGAAAACGCCCTAAAAA
TTGATTTGATTAACATTGCCCCACTCGATGACCTCCATCATCCAAAAGCGGCAATCGCTGAAGCGGAGCGCTTGGCGGCA
GAGGCGTTCCGTGCTGACGAGACCTTTTTCTCCGTTCAAGGGACATCGAGTGCCATCATGGCGATGATCATGGGTGTCGT
TGGCCCGAACGAAAAAATCATCGTGCCACGGAACGTCCATAAATCCGTCATGTCCGCGCTCGTCTTAACGGGTGCCCACC
CGGTCTTCATCCACCCGGAATTTGATGAAACATATGGCATCGCCCACGGAATCACGGCTAGCGCCGTAGAACGCGCGCTT
GAACTTCATCCGGACACGAAAGCCGTACTCGTCATCAACCCGACTTATTTCGGGGTCGCAGGTGATTTAGAACGTATCGT
GTCCGTCGCGCATGCACAAGACGTTCCAGTACTTGTCGATGAGGCACACGGCGTTCATCTTCCGTTTCACGATGAACTTC
CGCTCTCGGCGATGCAAGCGGGAGCAGATGTGGCGGCGACGAGTGTGCACAAGCTTGGTGGTTCAATGACAGGCAGTTCG
ATTTTGAACGTACGCCGCGGACTCGTCTCGCCAGAACGAATTCACGCAATGCTCTCTATGATTACAACGACGTCAACATC
CTATTTGCTCCTCGCTTCTCTCGACGCGGCACGTCGACAGTTAGCGACAAAGGGTCACATGATGAATGAGCGTGCACTCG
AGCTTGCTAGAACGGCCCGTACGGCAATCAATCACATGCCGAACTTATCGGTATACGGTCATGCCGAGTTGCATTCTGAA
TCGACTTACGCGCTCGATGAAACGAAAGTACTCGTATCCGTGCGTGAACTTGGGGTAACTGGATTTGAAGTCGAGAAATA
TCTTCGCGACAAACACCGCATCGAAGTCGAGATGTCCGATTTATTGAATGTGCTCTTCATCGTCACATCAGCGGACGACG
AATCAACGATTCAAGCGTTGATTGAAGCGATGCGAGATGTCGTTTCTGTTTACCAAAAGTCTGGGAACGACTCATTATCC
ATCATGCTCCCAGAGATTCCACCACTTGCGCTCAGTCCTCGTGATGCGTTTTATGAAGAGACGGAGACGATCCCTCTCGA
AAACGCAGTCGGGCGTATTTCAGCGGAATTCATCATGGTGTATCCACCTGGAATTCCAATCATCATTCCAGGTGAATTGA
TTACGACATCGACACTCGAATACATCATGGCCAACATTGAAGCGGGTCTTCCCGTACAAGGTCTTGAAGATGAGTCGCTG
CAAATGATTAAAGTCATCCAACAAACAAAAGCGATTCGCTAA

Upstream 100 bases:

>100_bases
AAATCTCTATAGTTTTTTTGTTGCTTCTTTTTTAAAAACAACATATATCATAACGATACTATTCATCTTATAAATAAACT
GATTCAAGGGGGATTTACGA

Downstream 100 bases:

>100_bases
ATAAAAAATGAGCCGGTCATCATGACCGGCTCATTTTTTATGTCATCTCAGAAAAGGTGGCTGTAGATGATCGAATTGCT
TCCCCTAGTGCCTATTATAA

Product: Orn/Lys/Arg decarboxylase major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MKLKGATQLETPLFDTLLEHVDSNPIAFHIPGHKSGKGMDPEFRDFIGENALKIDLINIAPLDDLHHPKAAIAEAERLAA
EAFRADETFFSVQGTSSAIMAMIMGVVGPNEKIIVPRNVHKSVMSALVLTGAHPVFIHPEFDETYGIAHGITASAVERAL
ELHPDTKAVLVINPTYFGVAGDLERIVSVAHAQDVPVLVDEAHGVHLPFHDELPLSAMQAGADVAATSVHKLGGSMTGSS
ILNVRRGLVSPERIHAMLSMITTTSTSYLLLASLDAARRQLATKGHMMNERALELARTARTAINHMPNLSVYGHAELHSE
STYALDETKVLVSVRELGVTGFEVEKYLRDKHRIEVEMSDLLNVLFIVTSADDESTIQALIEAMRDVVSVYQKSGNDSLS
IMLPEIPPLALSPRDAFYEETETIPLENAVGRISAEFIMVYPPGIPIIIPGELITTSTLEYIMANIEAGLPVQGLEDESL
QMIKVIQQTKAIR

Sequences:

>Translated_493_residues
MKLKGATQLETPLFDTLLEHVDSNPIAFHIPGHKSGKGMDPEFRDFIGENALKIDLINIAPLDDLHHPKAAIAEAERLAA
EAFRADETFFSVQGTSSAIMAMIMGVVGPNEKIIVPRNVHKSVMSALVLTGAHPVFIHPEFDETYGIAHGITASAVERAL
ELHPDTKAVLVINPTYFGVAGDLERIVSVAHAQDVPVLVDEAHGVHLPFHDELPLSAMQAGADVAATSVHKLGGSMTGSS
ILNVRRGLVSPERIHAMLSMITTTSTSYLLLASLDAARRQLATKGHMMNERALELARTARTAINHMPNLSVYGHAELHSE
STYALDETKVLVSVRELGVTGFEVEKYLRDKHRIEVEMSDLLNVLFIVTSADDESTIQALIEAMRDVVSVYQKSGNDSLS
IMLPEIPPLALSPRDAFYEETETIPLENAVGRISAEFIMVYPPGIPIIIPGELITTSTLEYIMANIEAGLPVQGLEDESL
QMIKVIQQTKAIR
>Mature_493_residues
MKLKGATQLETPLFDTLLEHVDSNPIAFHIPGHKSGKGMDPEFRDFIGENALKIDLINIAPLDDLHHPKAAIAEAERLAA
EAFRADETFFSVQGTSSAIMAMIMGVVGPNEKIIVPRNVHKSVMSALVLTGAHPVFIHPEFDETYGIAHGITASAVERAL
ELHPDTKAVLVINPTYFGVAGDLERIVSVAHAQDVPVLVDEAHGVHLPFHDELPLSAMQAGADVAATSVHKLGGSMTGSS
ILNVRRGLVSPERIHAMLSMITTTSTSYLLLASLDAARRQLATKGHMMNERALELARTARTAINHMPNLSVYGHAELHSE
STYALDETKVLVSVRELGVTGFEVEKYLRDKHRIEVEMSDLLNVLFIVTSADDESTIQALIEAMRDVVSVYQKSGNDSLS
IMLPEIPPLALSPRDAFYEETETIPLENAVGRISAEFIMVYPPGIPIIIPGELITTSTLEYIMANIEAGLPVQGLEDESL
QMIKVIQQTKAIR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=573, Percent_Identity=24.2582897033159, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786384, Length=571, Percent_Identity=23.4676007005254, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786909, Length=589, Percent_Identity=24.7877758913413, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082193, Length=585, Percent_Identity=23.4188034188034, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI221142684, Length=299, Percent_Identity=29.0969899665552, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53684; Mature: 53684

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKGATQLETPLFDTLLEHVDSNPIAFHIPGHKSGKGMDPEFRDFIGENALKIDLINIA
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEEC
PLDDLHHPKAAIAEAERLAAEAFRADETFFSVQGTSSAIMAMIMGVVGPNEKIIVPRNVH
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCHHH
KSVMSALVLTGAHPVFIHPEFDETYGIAHGITASAVERALELHPDTKAVLVINPTYFGVA
HHHHHHHHHCCCCEEEEECCCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCEECCH
GDLERIVSVAHAQDVPVLVDEAHGVHLPFHDELPLSAMQAGADVAATSVHKLGGSMTGSS
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHH
ILNVRRGLVSPERIHAMLSMITTTSTSYLLLASLDAARRQLATKGHMMNERALELARTAR
HHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TAINHMPNLSVYGHAELHSESTYALDETKVLVSVRELGVTGFEVEKYLRDKHRIEVEMSD
HHHHCCCCCEEEECCEECCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEHHH
LLNVLFIVTSADDESTIQALIEAMRDVVSVYQKSGNDSLSIMLPEIPPLALSPRDAFYEE
HHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHC
TETIPLENAVGRISAEFIMVYPPGIPIIIPGELITTSTLEYIMANIEAGLPVQGLEDESL
CCCCCHHHHHCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
QMIKVIQQTKAIR
HHHHHHHHHHCCC
>Mature Secondary Structure
MKLKGATQLETPLFDTLLEHVDSNPIAFHIPGHKSGKGMDPEFRDFIGENALKIDLINIA
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEEC
PLDDLHHPKAAIAEAERLAAEAFRADETFFSVQGTSSAIMAMIMGVVGPNEKIIVPRNVH
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCHHH
KSVMSALVLTGAHPVFIHPEFDETYGIAHGITASAVERALELHPDTKAVLVINPTYFGVA
HHHHHHHHHCCCCEEEEECCCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCEECCH
GDLERIVSVAHAQDVPVLVDEAHGVHLPFHDELPLSAMQAGADVAATSVHKLGGSMTGSS
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHH
ILNVRRGLVSPERIHAMLSMITTTSTSYLLLASLDAARRQLATKGHMMNERALELARTAR
HHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TAINHMPNLSVYGHAELHSESTYALDETKVLVSVRELGVTGFEVEKYLRDKHRIEVEMSD
HHHHCCCCCEEEECCEECCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEHHH
LLNVLFIVTSADDESTIQALIEAMRDVVSVYQKSGNDSLSIMLPEIPPLALSPRDAFYEE
HHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHC
TETIPLENAVGRISAEFIMVYPPGIPIIIPGELITTSTLEYIMANIEAGLPVQGLEDESL
CCCCCHHHHHCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
QMIKVIQQTKAIR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]