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The map label for this gene is mecA

Identifier: 229918458

GI number: 229918458

Start: 2716255

End: 2716911

Strand: Direct

Name: mecA

Synonym: EAT1b_2745

Alternate gene names: 229918458

Gene position: 2716255-2716911 (Clockwise)

Preceding gene: 229918457

Following gene: 229918459

Centisome position: 90.55

GC content: 43.84

Gene sequence:

>657_bases
GTGAAAATTGAGCGCATCAATGATAATACCGTCAAATTTTTCATCACATACGTGGATATCGAAAAACGTGGTTTTGCTCG
TGATGAAATTTGGTACAACCGAGAACGTGGCGAGCAGCTGTTCTGGCAAATGATGGACGAGGCTCACGAACGTGAAGACA
TCTCGTTTGATGGTCCACTATGGATTCAAGTACAAGCTTTTGAAAAAGGTCTAGAAGTGACTGTGACAATCGCGAAAAAT
GTAATGGACACGGAAGACGATTCTGAACTCGGTTCGCTTCTTCGATCAGCAATCGATGAGGCACGGGATCAACAATCGGT
ACTCGACCAATTGAGTGAGTTGGATGAACTTGAAGCCGAGGCAGATGCTTGGGCACCACTCGCGATGGAAACAAATGATT
TCGAGGCAATCATTTCGCTGAGTAAACGTACAGGAGACATGTTCAGCGATCTTGATTTGAAACTATATCACTATCAAGAC
CGTTACTACTTGTGGATTGATTTCCCGGATGAAATGGAACCGGAAGACGAAGAGAATGCACTCAGTCTTTTAGCAGAGTA
TTTAACATTCAGTACACAGACGCAACCGATGCTTGAAGAGTATGGGAAACTCATTCTCGATGGCGACGTCTTTGCGAAAG
TGCGTCACTATTTTTAA

Upstream 100 bases:

>100_bases
CTAGATTGAACGATGTTAAAAAGGGTACAAAGATAACAAGACAATTTCCCCTCTCCTCCTTATGTGAATTGGGAGCGAGG
TGAGAAGGGAGTGGACAATC

Downstream 100 bases:

>100_bases
TGGTACATCGCCTGTTCAGTTGGACAGGCGATTTTTTCAAATCGACGGTAAAGAGGTGTTGGTATGGTGAGACGAATTCG
ATTACTACTTGATGACAGCG

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKIERINDNTVKFFITYVDIEKRGFARDEIWYNRERGEQLFWQMMDEAHEREDISFDGPLWIQVQAFEKGLEVTVTIAKN
VMDTEDDSELGSLLRSAIDEARDQQSVLDQLSELDELEAEADAWAPLAMETNDFEAIISLSKRTGDMFSDLDLKLYHYQD
RYYLWIDFPDEMEPEDEENALSLLAEYLTFSTQTQPMLEEYGKLILDGDVFAKVRHYF

Sequences:

>Translated_218_residues
MKIERINDNTVKFFITYVDIEKRGFARDEIWYNRERGEQLFWQMMDEAHEREDISFDGPLWIQVQAFEKGLEVTVTIAKN
VMDTEDDSELGSLLRSAIDEARDQQSVLDQLSELDELEAEADAWAPLAMETNDFEAIISLSKRTGDMFSDLDLKLYHYQD
RYYLWIDFPDEMEPEDEENALSLLAEYLTFSTQTQPMLEEYGKLILDGDVFAKVRHYF
>Mature_218_residues
MKIERINDNTVKFFITYVDIEKRGFARDEIWYNRERGEQLFWQMMDEAHEREDISFDGPLWIQVQAFEKGLEVTVTIAKN
VMDTEDDSELGSLLRSAIDEARDQQSVLDQLSELDELEAEADAWAPLAMETNDFEAIISLSKRTGDMFSDLDLKLYHYQD
RYYLWIDFPDEMEPEDEENALSLLAEYLTFSTQTQPMLEEYGKLILDGDVFAKVRHYF

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA_EXISA (C4L574)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887104.1
- GeneID:   7868950
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2745
- OMA:   VNENTIR
- ProtClustDB:   PRK02315
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 25674; Mature: 25674

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIERINDNTVKFFITYVDIEKRGFARDEIWYNRERGEQLFWQMMDEAHEREDISFDGPL
CCCCCCCCCEEEEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIQVQAFEKGLEVTVTIAKNVMDTEDDSELGSLLRSAIDEARDQQSVLDQLSELDELEAE
EEEEEEHHCCCEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAWAPLAMETNDFEAIISLSKRTGDMFSDLDLKLYHYQDRYYLWIDFPDEMEPEDEENA
CCCCCCEEECCCCHHHHHHHHHHCCCHHHCCCEEEEEECCEEEEEEECCCCCCCCCHHHH
LSLLAEYLTFSTQTQPMLEEYGKLILDGDVFAKVRHYF
HHHHHHHHHHCCCCCHHHHHCCCEEECCHHHHHHHHCC
>Mature Secondary Structure
MKIERINDNTVKFFITYVDIEKRGFARDEIWYNRERGEQLFWQMMDEAHEREDISFDGPL
CCCCCCCCCEEEEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIQVQAFEKGLEVTVTIAKNVMDTEDDSELGSLLRSAIDEARDQQSVLDQLSELDELEAE
EEEEEEHHCCCEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAWAPLAMETNDFEAIISLSKRTGDMFSDLDLKLYHYQDRYYLWIDFPDEMEPEDEENA
CCCCCCEEECCCCHHHHHHHHHHCCCHHHCCCEEEEEECCEEEEEEECCCCCCCCCHHHH
LSLLAEYLTFSTQTQPMLEEYGKLILDGDVFAKVRHYF
HHHHHHHHHHCCCCCHHHHHCCCEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA