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The map label for this gene is nadA [H]

Identifier: 229918405

GI number: 229918405

Start: 2656653

End: 2657732

Strand: Direct

Name: nadA [H]

Synonym: EAT1b_2690

Alternate gene names: 229918405

Gene position: 2656653-2657732 (Clockwise)

Preceding gene: 229918404

Following gene: 229918406

Centisome position: 88.56

GC content: 55.19

Gene sequence:

>1080_bases
ATGCAACTACTCGGAACACTCCCGCCGACGTACGCTAACCTGTCGGTGGAGGAGATGGAGACTCGGATTCAGGCGGTCAA
AGACCGACTCGGGACGCGTCTCTTTTTACCGGCCCATCATTATCAAAAAGACGAGGTCGTTCAATTCGCGGACGCGACAG
GAGATTCGCTCCAGCTCGCACGGCTCGCAGAACAGATGAGCGAAGCCGAATTCATCGTCTTTTGTGGTGTCCACTTCATG
GCAGAGACAGCAGACATGTTGACACGGGACGACCAGATTGTCGTCTTACCTGATATGCGTGCCGGCTGTTCGATGGCAGA
CATGGCCGATATCGATCAGACGGAGATTGCTTGGGAAGAACTGACGGAACGATTTGGAGAGGACATCATCCCGATTACAT
ACGTCAATTCTACAGCGGCCATCAAAGCGTTCGTTGGTCGTCACGGCGGGGCGACCGTCACATCGTCGAACGCCCATGAA
ATCGTCCGGTGGGCGCTTGAGGCAGGTGAACGCATCTTGTTCCTTCCCGATCAACATCTCGGGCGGAACACGGCGTATGA
TCTCGGCATCCCACTCGAGGCGATGGCTGTTTGGGATCCGCTCCGTGAAGAATTGGTCGCGGAGGGAGATGATGAGCAAG
TGAAAGTCATCTTATGGAAGGGACACTGTTCTGTCCATGAGAAGTTCACGGTATCGCAAATTCAGGCGTTCCGTGAGCGT
GAGCCGGATCGTCGCATCATCGTCCATCCGGAATGTACGTTTGATGTCGTCCAGGCTGCGGACGAGGCGGGATCGACATC
GTATATCATCGACAAGATTGACGCGAGCGCACCGGGGACGAAGTGGGCGGTCGGAACGGAGATGAACCTCGTCAACCGTC
TGGCGGCGACTTACCCACACCTCGATATCGTTTCATTGAACCCGTTCATGTGTCCGTGCCTCACGATGAATCGAATCGAC
TTGCCACATCTACTGTGGGCGCTCGAGTCGCTCGAGACGGACCCTGTGAACATCATTCGCGTCGATCATGAGACGACAGA
GTTCTCGAAACGTGCACTTGAACGTATGCTCGCGCGATAA

Upstream 100 bases:

>100_bases
GATTATCGAGGCATTCGCATCGATGTCATCTCGCTCGGGCAATTGACTCATTCGGTACGCGCGTTCGATTGCAGTTTGAA
TTTACAAGGAGGAATGAAAG

Downstream 100 bases:

>100_bases
TTGCTAGAGGACAGGTAAACGCCTGTCCTTTTTTCGTGTCGCCCATTATGGTACAATAAATGCAGTTTTTCCGACCGAAA
AGGAGAGTACACCGTGATTG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQLLGTLPPTYANLSVEEMETRIQAVKDRLGTRLFLPAHHYQKDEVVQFADATGDSLQLARLAEQMSEAEFIVFCGVHFM
AETADMLTRDDQIVVLPDMRAGCSMADMADIDQTEIAWEELTERFGEDIIPITYVNSTAAIKAFVGRHGGATVTSSNAHE
IVRWALEAGERILFLPDQHLGRNTAYDLGIPLEAMAVWDPLREELVAEGDDEQVKVILWKGHCSVHEKFTVSQIQAFRER
EPDRRIIVHPECTFDVVQAADEAGSTSYIIDKIDASAPGTKWAVGTEMNLVNRLAATYPHLDIVSLNPFMCPCLTMNRID
LPHLLWALESLETDPVNIIRVDHETTEFSKRALERMLAR

Sequences:

>Translated_359_residues
MQLLGTLPPTYANLSVEEMETRIQAVKDRLGTRLFLPAHHYQKDEVVQFADATGDSLQLARLAEQMSEAEFIVFCGVHFM
AETADMLTRDDQIVVLPDMRAGCSMADMADIDQTEIAWEELTERFGEDIIPITYVNSTAAIKAFVGRHGGATVTSSNAHE
IVRWALEAGERILFLPDQHLGRNTAYDLGIPLEAMAVWDPLREELVAEGDDEQVKVILWKGHCSVHEKFTVSQIQAFRER
EPDRRIIVHPECTFDVVQAADEAGSTSYIIDKIDASAPGTKWAVGTEMNLVNRLAATYPHLDIVSLNPFMCPCLTMNRID
LPHLLWALESLETDPVNIIRVDHETTEFSKRALERMLAR
>Mature_359_residues
MQLLGTLPPTYANLSVEEMETRIQAVKDRLGTRLFLPAHHYQKDEVVQFADATGDSLQLARLAEQMSEAEFIVFCGVHFM
AETADMLTRDDQIVVLPDMRAGCSMADMADIDQTEIAWEELTERFGEDIIPITYVNSTAAIKAFVGRHGGATVTSSNAHE
IVRWALEAGERILFLPDQHLGRNTAYDLGIPLEAMAVWDPLREELVAEGDDEQVKVILWKGHCSVHEKFTVSQIQAFRER
EPDRRIIVHPECTFDVVQAADEAGSTSYIIDKIDASAPGTKWAVGTEMNLVNRLAATYPHLDIVSLNPFMCPCLTMNRID
LPHLLWALESLETDPVNIIRVDHETTEFSKRALERMLAR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=367, Percent_Identity=27.5204359673025, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40318; Mature: 40318

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLGTLPPTYANLSVEEMETRIQAVKDRLGTRLFLPAHHYQKDEVVQFADATGDSLQLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCHHHHHHHHCCCCCHHHHH
RLAEQMSEAEFIVFCGVHFMAETADMLTRDDQIVVLPDMRAGCSMADMADIDQTEIAWEE
HHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCCCHHHHHHHH
LTERFGEDIIPITYVNSTAAIKAFVGRHGGATVTSSNAHEIVRWALEAGERILFLPDQHL
HHHHHCCCCEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCEEEECCCHHC
GRNTAYDLGIPLEAMAVWDPLREELVAEGDDEQVKVILWKGHCSVHEKFTVSQIQAFRER
CCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
EPDRRIIVHPECTFDVVQAADEAGSTSYIIDKIDASAPGTKWAVGTEMNLVNRLAATYPH
CCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHCCC
LDIVSLNPFMCPCLTMNRIDLPHLLWALESLETDPVNIIRVDHETTEFSKRALERMLAR
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLLGTLPPTYANLSVEEMETRIQAVKDRLGTRLFLPAHHYQKDEVVQFADATGDSLQLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCHHHHHHHHCCCCCHHHHH
RLAEQMSEAEFIVFCGVHFMAETADMLTRDDQIVVLPDMRAGCSMADMADIDQTEIAWEE
HHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCCCHHHHHHHH
LTERFGEDIIPITYVNSTAAIKAFVGRHGGATVTSSNAHEIVRWALEAGERILFLPDQHL
HHHHHCCCCEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCEEEECCCHHC
GRNTAYDLGIPLEAMAVWDPLREELVAEGDDEQVKVILWKGHCSVHEKFTVSQIQAFRER
CCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
EPDRRIIVHPECTFDVVQAADEAGSTSYIIDKIDASAPGTKWAVGTEMNLVNRLAATYPH
CCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHCCC
LDIVSLNPFMCPCLTMNRIDLPHLLWALESLETDPVNIIRVDHETTEFSKRALERMLAR
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA