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The map label for this gene is obg [H]

Identifier: 229918397

GI number: 229918397

Start: 2648465

End: 2649754

Strand: Direct

Name: obg [H]

Synonym: EAT1b_2682

Alternate gene names: 229918397

Gene position: 2648465-2649754 (Clockwise)

Preceding gene: 229918396

Following gene: 229918398

Centisome position: 88.29

GC content: 52.64

Gene sequence:

>1290_bases
ATGTTTGTCGATCAGGTTAATATTTTTGTAAAAGCTGGAGACGGCGGAAAAGGGATGGTCGCTTTCCGTCGCGAGAAATA
CGTTCCAGACGGTGGTCCTGCAGGTGGTGACGGTGGTCATGGTGGAGACGTCATCTTTGAAGTAGAAGAAGGATTGCGGA
CGCTCGTTGATTTCCGCTATTCGAAGAAGTTTATCGCCCATGATGGCGAAAAAGGGATGTCAAAAGGGATGCACGGACGT
AAAGCGAAACCGCTCATCGTCAAAGTCCCACCTGGCACAATCGTGTTCGACGCCGAGACGGATACCGTCATCGCGGACTT
GACCGAGCACGGTCAACAAGCGACGATCGCAAAAGGTGGTCGTGGTGGTCGCGGGAACTGTCGTTTTGCGACGCCTGCCA
ACCCGGCTCCAGAAATCGCGGAGAACGGGGAACCAGGTCAAGAACGTGAACTCCGTCTCGAGTTGAAACTTCTCGCAGAC
GTCGGTCTCGTCGGATTCCCGTCTGTCGGGAAGTCAACGCTTCTCTCGGTCGTCTCGTCGGCACGTCCGAAAATCGGTGC
GTACCACTTCACGACAATCACACCGAACCTCGGTGTCGTCAAGACAGCGGACGACCGTAGTTTCGTCATGGCTGACCTTC
CAGGCCTCATCGAAGGAGCGAGCCAAGGCGTTGGTCTCGGTCACCAGTTCCTTCGCCATATCGAACGGACGAAAGTCATC
GTTCACATGATCGATATGAGTGGTATGGAAGGACGCGATCCGTTTGAAGACTACACGACGATCAACCGTGAGCTCGAGTC
GTACAACTTACGTCTCCTTGAGCGTCCACAAGTCGTCGTGGCGAACAAAATGGATATGCCGGACGCAGCGGAACATCTTG
AAGAGTTCAAGAAGAAGGTAGGGGACGATGTCAAAGTCTTCCCGATCTCAGCACTCGCTCAAGACGGTCTTCGCAACTTG
TTGATCGAAGTGGCGAACTTTGTCGATACGACACCAGAATTCCCACTCGATGAGCTCGAAGAGAAGACAGCGACGCCTCG
TGTCGTGTATCGTTATGAGAAGGAAGAGAAAGGCTATCAAATCCACATCGATGAATACGATCGCTTCGTGATCACGGGCC
CTCGTATCGAGAAGCTCTTCAAGATGACGAACTTTGACCATGATGAGTCGATCAAACGATTTGCTCGTCAAATGCGTCAA
ATGGGCGTCGATGACGATCTTCGTAAGTTGGGTGCCGAGGACGGTAGTGTCGTCGCGATCCTCGACTTCGAATTCGAGTT
TGTGGAATAA

Upstream 100 bases:

>100_bases
TCGCGTCACGGGTACTGTCCCGGACGATGTGAAGGCATCAGCCGATGTGTACGAACAGAACGTAGATACCACTACGTTTC
ACATAAAGGAGGGGAAATAA

Downstream 100 bases:

>100_bases
AAAATTTTTTGTTAAGAAGAAACGGAGTGTGAAGCTAACGTGGACCCTGTGCCCTCGTCAAGTTTAATTCTATATGTAGT
TCTCGTCATGTTGTCAGCGT

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFVDQVNIFVKAGDGGKGMVAFRREKYVPDGGPAGGDGGHGGDVIFEVEEGLRTLVDFRYSKKFIAHDGEKGMSKGMHGR
KAKPLIVKVPPGTIVFDAETDTVIADLTEHGQQATIAKGGRGGRGNCRFATPANPAPEIAENGEPGQERELRLELKLLAD
VGLVGFPSVGKSTLLSVVSSARPKIGAYHFTTITPNLGVVKTADDRSFVMADLPGLIEGASQGVGLGHQFLRHIERTKVI
VHMIDMSGMEGRDPFEDYTTINRELESYNLRLLERPQVVVANKMDMPDAAEHLEEFKKKVGDDVKVFPISALAQDGLRNL
LIEVANFVDTTPEFPLDELEEKTATPRVVYRYEKEEKGYQIHIDEYDRFVITGPRIEKLFKMTNFDHDESIKRFARQMRQ
MGVDDDLRKLGAEDGSVVAILDFEFEFVE

Sequences:

>Translated_429_residues
MFVDQVNIFVKAGDGGKGMVAFRREKYVPDGGPAGGDGGHGGDVIFEVEEGLRTLVDFRYSKKFIAHDGEKGMSKGMHGR
KAKPLIVKVPPGTIVFDAETDTVIADLTEHGQQATIAKGGRGGRGNCRFATPANPAPEIAENGEPGQERELRLELKLLAD
VGLVGFPSVGKSTLLSVVSSARPKIGAYHFTTITPNLGVVKTADDRSFVMADLPGLIEGASQGVGLGHQFLRHIERTKVI
VHMIDMSGMEGRDPFEDYTTINRELESYNLRLLERPQVVVANKMDMPDAAEHLEEFKKKVGDDVKVFPISALAQDGLRNL
LIEVANFVDTTPEFPLDELEEKTATPRVVYRYEKEEKGYQIHIDEYDRFVITGPRIEKLFKMTNFDHDESIKRFARQMRQ
MGVDDDLRKLGAEDGSVVAILDFEFEFVE
>Mature_429_residues
MFVDQVNIFVKAGDGGKGMVAFRREKYVPDGGPAGGDGGHGGDVIFEVEEGLRTLVDFRYSKKFIAHDGEKGMSKGMHGR
KAKPLIVKVPPGTIVFDAETDTVIADLTEHGQQATIAKGGRGGRGNCRFATPANPAPEIAENGEPGQERELRLELKLLAD
VGLVGFPSVGKSTLLSVVSSARPKIGAYHFTTITPNLGVVKTADDRSFVMADLPGLIEGASQGVGLGHQFLRHIERTKVI
VHMIDMSGMEGRDPFEDYTTINRELESYNLRLLERPQVVVANKMDMPDAAEHLEEFKKKVGDDVKVFPISALAQDGLRNL
LIEVANFVDTTPEFPLDELEEKTATPRVVYRYEKEEKGYQIHIDEYDRFVITGPRIEKLFKMTNFDHDESIKRFARQMRQ
MGVDDDLRKLGAEDGSVVAILDFEFEFVE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=337, Percent_Identity=40.0593471810089, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI111955139, Length=307, Percent_Identity=35.5048859934853, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI111955063, Length=206, Percent_Identity=37.378640776699, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4557537, Length=114, Percent_Identity=40.3508771929825, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789574, Length=355, Percent_Identity=46.1971830985916, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=325, Percent_Identity=39.0769230769231, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=351, Percent_Identity=30.7692307692308, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71981008, Length=220, Percent_Identity=30.4545454545455, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=32.3741007194245, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=37.2881355932203, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=36.4102564102564, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=34.9206349206349, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=39.1585760517799, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20129375, Length=335, Percent_Identity=37.910447761194, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=37.007874015748, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=38.4615384615385, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640873, Length=148, Percent_Identity=34.4594594594595, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640877, Length=148, Percent_Identity=34.4594594594595, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640875, Length=148, Percent_Identity=34.4594594594595, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47513; Mature: 47513

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVNIFVKAGDGGKGMVAFRREKYVPDGGPAGGDGGHGGDVIFEVEEGLRTLVDFRY
CCEEEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
SKKFIAHDGEKGMSKGMHGRKAKPLIVKVPPGTIVFDAETDTVIADLTEHGQQATIAKGG
HHHHHHCCCHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCEEEHHHHHCCCEEEEECCC
RGGRGNCRFATPANPAPEIAENGEPGQERELRLELKLLADVGLVGFPSVGKSTLLSVVSS
CCCCCCEEECCCCCCCCHHHCCCCCCCCHHHEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIGAYHFTTITPNLGVVKTADDRSFVMADLPGLIEGASQGVGLGHQFLRHIERTKVI
CCCCCCEEEEEEECCCCCEEEECCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGMEGRDPFEDYTTINRELESYNLRLLERPQVVVANKMDMPDAAEHLEEFKKKV
EEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHC
GDDVKVFPISALAQDGLRNLLIEVANFVDTTPEFPLDELEEKTATPRVVYRYEKEEKGYQ
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEE
IHIDEYDRFVITGPRIEKLFKMTNFDHDESIKRFARQMRQMGVDDDLRKLGAEDGSVVAI
EEEECCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEE
LDFEFEFVE
EEEEEEECC
>Mature Secondary Structure
MFVDQVNIFVKAGDGGKGMVAFRREKYVPDGGPAGGDGGHGGDVIFEVEEGLRTLVDFRY
CCEEEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
SKKFIAHDGEKGMSKGMHGRKAKPLIVKVPPGTIVFDAETDTVIADLTEHGQQATIAKGG
HHHHHHCCCHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCEEEHHHHHCCCEEEEECCC
RGGRGNCRFATPANPAPEIAENGEPGQERELRLELKLLADVGLVGFPSVGKSTLLSVVSS
CCCCCCEEECCCCCCCCHHHCCCCCCCCHHHEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIGAYHFTTITPNLGVVKTADDRSFVMADLPGLIEGASQGVGLGHQFLRHIERTKVI
CCCCCCEEEEEEECCCCCEEEECCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGMEGRDPFEDYTTINRELESYNLRLLERPQVVVANKMDMPDAAEHLEEFKKKV
EEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHC
GDDVKVFPISALAQDGLRNLLIEVANFVDTTPEFPLDELEEKTATPRVVYRYEKEEKGYQ
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEE
IHIDEYDRFVITGPRIEKLFKMTNFDHDESIKRFARQMRQMGVDDDLRKLGAEDGSVVAI
EEEECCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEE
LDFEFEFVE
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA