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The map label for this gene is fadR [H]

Identifier: 229918327

GI number: 229918327

Start: 2579658

End: 2580236

Strand: Direct

Name: fadR [H]

Synonym: EAT1b_2612

Alternate gene names: 229918327

Gene position: 2579658-2580236 (Clockwise)

Preceding gene: 229918326

Following gene: 229918328

Centisome position: 85.99

GC content: 45.42

Gene sequence:

>579_bases
ATGACAAATCATATTTCGAAAAGTGACCGAATCATTGATGCGGCGGTCAAAGTAATTGCTAATCATGGCTATCACGGTGC
AAAGGTGACAGCCATCGCTAAAGAGGCGGGTGTCGCGGACGGCACAATCTATTTGTACTTCAAAAACAAGGAGCATCTCT
TAATCGAATTGTTCCAAGCGAAAATGGGGCTGTTCATCGACTACTCGAAACAACAAATCGGGAACGAGACGACGGCCGGA
GATCAATTGTATCAGTTGATTGAATCGCATTTAAAGCAACTGTCGGCCGATTACGACCTCGCTGTCGTGACACAAATCGA
ATTGCGACAGTCGAATTTGGTGCTTCGCCAAAAAATCGGAGAAGTGCTCAAACCATATTTGAACTTAATCGATTCTGTCG
TCAAGCATGGAATCGAGACAGGAGAGTTCGACAAGGATTTAGACTATCGACTCGCCCGTCAAATGATTTTTGGCACAATC
GATGAGGTTGTGACGAGTTGGATGGCGAGCGGCTTCAAGTACGATCTGTTGTCGACGCTTCCAAATGTGCACCATATGTT
AAAGAAGGGGCTTACGTAA

Upstream 100 bases:

>100_bases
CAAGTGAAACAAAGCAGTTGACACCAAGCGTACGCATGATAGAATAATAAATGAATGAACCATCATTCATTTTTCTGCAG
CGGTAAGGAGCTTGGGGTTA

Downstream 100 bases:

>100_bases
CAGTGAGCCCTATCACTAGCTCAAAAAATGAATGCTGATTCATGAATGATGGGAAAGAATTGACTAAAGGGGGATCAACC
ATGAATATTTTTGTTTTGCT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTNHISKSDRIIDAAVKVIANHGYHGAKVTAIAKEAGVADGTIYLYFKNKEHLLIELFQAKMGLFIDYSKQQIGNETTAG
DQLYQLIESHLKQLSADYDLAVVTQIELRQSNLVLRQKIGEVLKPYLNLIDSVVKHGIETGEFDKDLDYRLARQMIFGTI
DEVVTSWMASGFKYDLLSTLPNVHHMLKKGLT

Sequences:

>Translated_192_residues
MTNHISKSDRIIDAAVKVIANHGYHGAKVTAIAKEAGVADGTIYLYFKNKEHLLIELFQAKMGLFIDYSKQQIGNETTAG
DQLYQLIESHLKQLSADYDLAVVTQIELRQSNLVLRQKIGEVLKPYLNLIDSVVKHGIETGEFDKDLDYRLARQMIFGTI
DEVVTSWMASGFKYDLLSTLPNVHHMLKKGLT
>Mature_191_residues
TNHISKSDRIIDAAVKVIANHGYHGAKVTAIAKEAGVADGTIYLYFKNKEHLLIELFQAKMGLFIDYSKQQIGNETTAGD
QLYQLIESHLKQLSADYDLAVVTQIELRQSNLVLRQKIGEVLKPYLNLIDSVVKHGIETGEFDKDLDYRLARQMIFGTID
EVVTSWMASGFKYDLLSTLPNVHHMLKKGLT

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21624; Mature: 21493

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHISKSDRIIDAAVKVIANHGYHGAKVTAIAKEAGVADGTIYLYFKNKEHLLIELFQA
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHH
KMGLFIDYSKQQIGNETTAGDQLYQLIESHLKQLSADYDLAVVTQIELRQSNLVLRQKIG
HHHHHEECHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHH
EVLKPYLNLIDSVVKHGIETGEFDKDLDYRLARQMIFGTIDEVVTSWMASGFKYDLLSTL
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
PNVHHMLKKGLT
HHHHHHHHHCCC
>Mature Secondary Structure 
TNHISKSDRIIDAAVKVIANHGYHGAKVTAIAKEAGVADGTIYLYFKNKEHLLIELFQA
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHH
KMGLFIDYSKQQIGNETTAGDQLYQLIESHLKQLSADYDLAVVTQIELRQSNLVLRQKIG
HHHHHEECHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHH
EVLKPYLNLIDSVVKHGIETGEFDKDLDYRLARQMIFGTIDEVVTSWMASGFKYDLLSTL
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
PNVHHMLKKGLT
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]