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The map label for this gene is kat [H]

Identifier: 229918244

GI number: 229918244

Start: 2486243

End: 2487712

Strand: Direct

Name: kat [H]

Synonym: EAT1b_2525

Alternate gene names: 229918244

Gene position: 2486243-2487712 (Clockwise)

Preceding gene: 229918243

Following gene: 229918246

Centisome position: 82.88

GC content: 50.54

Gene sequence:

>1470_bases
ATGGATCAACACCGTCAACTAACTACTAACCAAGGCGTACCAATCGGGGATAACGCCAACTCCATCACTGCGGGTCGTCG
GGGCCCGACGCTTCTCGAAGACTACCAACTAATTGAGAAATTAGCGCATTTCGATCGTGAACGTGTACCAGAACGAGTCG
TTCATGCAAGAGGCGCAGGGGCACATGGTGTCTTCACTGTAAAAAATAGTATGAAACGATATACAAAAGCCGCATTCTTG
CAAGAAGAGGGGCAAGAGACGCCTGTATTTGCACGTTTCTCGACCGTCATCCACGGATTGGGTTCACCGGAGACACTTCG
TGACCCACGCGGTTTTGCCGTCAAGTTTTATACGGAAGAAGGGAACTATGACTTCGTCGGAAACAACTTACCGGTCTTCT
TCATCCGTGACGCGATTAAATTCCCAGATGTGATTCACTCGCTCAAGCCGGACCCACAAACGAACCTTCAAGACCCGGAC
CGCTTCTTCGACTTCATGTCGCTTACGCCTGAATCAACGAACATGCTTCTTCATTTATTCAGTGACGAAGGCATCCCGGC
ATCGTATCGCCATATGCGCGGCTCATCTGTCCATTCCTTCAAGTGGGTGAATGAATTCGGCAACACGGTGTACATAAAGA
TGCGCTGGGTACCGAAGCAAGGCATTCAAAACTTGTCGATGGAAGAAGCGGCGAAAATCCAAGCGGAAGACTTCAACCAT
GCGACACGTGACTTGTTCAACGCGATTGAAAATGGAGACTATCCGGAATGGGATCTATATGTACAGATTTTAGACCCGGC
GGACATGGACAACTTTGATTTCGACCCGCTCGATGCCACAAAGGATTGGTTCGAAGATGTCATCCCGTATCAATTGGTCG
GAACGATGACCCTCAATAAAAACGTCGACAACTTCTTCGCCGAGACAGAATCTGTCGGCTTCAACCCGGGTGTTCTCGTT
CCAGGGATCCAGCCGTCAGAAGACAAGATGCTCCAAGGACGACTCTTCTCGTATTCGGATACGCAGCGTCACCGTATCGG
ACCGAACTATCTCCAACTTCCGATCAACTGCCCGTTCGCTCAAGTCGCGAACAACCAGCGTGACGGGGCGATGCCGTTTA
AGCAACAGACGAGCCCGGTCAACTACGAGCCGAACCGTTACGAAGACGCGCCGAAGCCGAATGCGGACTATATTGAGACA
CCGCAACCGATCACAGGCGTGACGGGTCGTCAGAAGATTGAGAAGACGAACGATTTCGGTCAAGCGGGAGAAGTGTATCG
CCGCTATTCTCAAGAAGAGAAGGATGCGCTCATCCGTAACCTCGTCGCTCACATCAAAGAAGTTCGTCATGAGAAGACCG
TTCTCCTCTTGATTTGCAACTTCTATCGTGCAGACCGTGAACTCGGGGAGCGTCTCTCGAATGAGTTGAACGTCGATCTC
GCACCATTCTTGAATCAAATGTCGAACTAA

Upstream 100 bases:

>100_bases
TGAAAAAAAGTTCGTGATTCACGAGCTTTTTATTTGTAATCATTCTAATCTTTGATTAATATCAAGATTGTAATGATTAT
AAATAATGGGAGGCAATCAT

Downstream 100 bases:

>100_bases
ACATGTAACCGCGGTCTTGTACCGCGGTTTTTTGTATGCGAAAAGACGTTCCTCTCATTGAGAAACGTCTCGTCAATCGT
GGTTATTCACCGACCATCCC

Product: Catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MDQHRQLTTNQGVPIGDNANSITAGRRGPTLLEDYQLIEKLAHFDRERVPERVVHARGAGAHGVFTVKNSMKRYTKAAFL
QEEGQETPVFARFSTVIHGLGSPETLRDPRGFAVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPQTNLQDPD
RFFDFMSLTPESTNMLLHLFSDEGIPASYRHMRGSSVHSFKWVNEFGNTVYIKMRWVPKQGIQNLSMEEAAKIQAEDFNH
ATRDLFNAIENGDYPEWDLYVQILDPADMDNFDFDPLDATKDWFEDVIPYQLVGTMTLNKNVDNFFAETESVGFNPGVLV
PGIQPSEDKMLQGRLFSYSDTQRHRIGPNYLQLPINCPFAQVANNQRDGAMPFKQQTSPVNYEPNRYEDAPKPNADYIET
PQPITGVTGRQKIEKTNDFGQAGEVYRRYSQEEKDALIRNLVAHIKEVRHEKTVLLLICNFYRADRELGERLSNELNVDL
APFLNQMSN

Sequences:

>Translated_489_residues
MDQHRQLTTNQGVPIGDNANSITAGRRGPTLLEDYQLIEKLAHFDRERVPERVVHARGAGAHGVFTVKNSMKRYTKAAFL
QEEGQETPVFARFSTVIHGLGSPETLRDPRGFAVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPQTNLQDPD
RFFDFMSLTPESTNMLLHLFSDEGIPASYRHMRGSSVHSFKWVNEFGNTVYIKMRWVPKQGIQNLSMEEAAKIQAEDFNH
ATRDLFNAIENGDYPEWDLYVQILDPADMDNFDFDPLDATKDWFEDVIPYQLVGTMTLNKNVDNFFAETESVGFNPGVLV
PGIQPSEDKMLQGRLFSYSDTQRHRIGPNYLQLPINCPFAQVANNQRDGAMPFKQQTSPVNYEPNRYEDAPKPNADYIET
PQPITGVTGRQKIEKTNDFGQAGEVYRRYSQEEKDALIRNLVAHIKEVRHEKTVLLLICNFYRADRELGERLSNELNVDL
APFLNQMSN
>Mature_489_residues
MDQHRQLTTNQGVPIGDNANSITAGRRGPTLLEDYQLIEKLAHFDRERVPERVVHARGAGAHGVFTVKNSMKRYTKAAFL
QEEGQETPVFARFSTVIHGLGSPETLRDPRGFAVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPQTNLQDPD
RFFDFMSLTPESTNMLLHLFSDEGIPASYRHMRGSSVHSFKWVNEFGNTVYIKMRWVPKQGIQNLSMEEAAKIQAEDFNH
ATRDLFNAIENGDYPEWDLYVQILDPADMDNFDFDPLDATKDWFEDVIPYQLVGTMTLNKNVDNFFAETESVGFNPGVLV
PGIQPSEDKMLQGRLFSYSDTQRHRIGPNYLQLPINCPFAQVANNQRDGAMPFKQQTSPVNYEPNRYEDAPKPNADYIET
PQPITGVTGRQKIEKTNDFGQAGEVYRRYSQEEKDALIRNLVAHIKEVRHEKTVLLLICNFYRADRELGERLSNELNVDL
APFLNQMSN

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=446, Percent_Identity=48.4304932735426, Blast_Score=429, Evalue=1e-120,
Organism=Escherichia coli, GI48994891, Length=426, Percent_Identity=48.1220657276995, Blast_Score=388, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71998444, Length=468, Percent_Identity=44.8717948717949, Blast_Score=430, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=44.9152542372881, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=44.9152542372881, Blast_Score=429, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6320462, Length=372, Percent_Identity=46.505376344086, Blast_Score=341, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6321525, Length=510, Percent_Identity=37.4509803921569, Blast_Score=323, Evalue=5e-89,
Organism=Drosophila melanogaster, GI17981717, Length=481, Percent_Identity=44.4906444906445, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI19920968, Length=485, Percent_Identity=40.4123711340206, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55941; Mature: 55941

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQHRQLTTNQGVPIGDNANSITAGRRGPTLLEDYQLIEKLAHFDRERVPERVVHARGAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGVFTVKNSMKRYTKAAFLQEEGQETPVFARFSTVIHGLGSPETLRDPRGFAVKFYTEE
CCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEEC
GNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPQTNLQDPDRFFDFMSLTPESTNMLLHLF
CCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
SDEGIPASYRHMRGSSVHSFKWVNEFGNTVYIKMRWVPKQGIQNLSMEEAAKIQAEDFNH
CCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEEEEECCHHHHCCCCHHHHHHHHHHHCCH
ATRDLFNAIENGDYPEWDLYVQILDPADMDNFDFDPLDATKDWFEDVIPYQLVGTMTLNK
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCHHEEEEEEECC
NVDNFFAETESVGFNPGVLVPGIQPSEDKMLQGRLFSYSDTQRHRIGPNYLQLPINCPFA
CHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHCEEECCCCCHHHCCCCCEEEEECCCCHH
QVANNQRDGAMPFKQQTSPVNYEPNRYEDAPKPNADYIETPQPITGVTGRQKIEKTNDFG
HHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
QAGEVYRRYSQEEKDALIRNLVAHIKEVRHEKTVLLLICNFYRADRELGERLSNELNVDL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHCCCCH
APFLNQMSN
HHHHHHHCC
>Mature Secondary Structure
MDQHRQLTTNQGVPIGDNANSITAGRRGPTLLEDYQLIEKLAHFDRERVPERVVHARGAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGVFTVKNSMKRYTKAAFLQEEGQETPVFARFSTVIHGLGSPETLRDPRGFAVKFYTEE
CCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEEC
GNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPQTNLQDPDRFFDFMSLTPESTNMLLHLF
CCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
SDEGIPASYRHMRGSSVHSFKWVNEFGNTVYIKMRWVPKQGIQNLSMEEAAKIQAEDFNH
CCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEEEEECCHHHHCCCCHHHHHHHHHHHCCH
ATRDLFNAIENGDYPEWDLYVQILDPADMDNFDFDPLDATKDWFEDVIPYQLVGTMTLNK
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCHHEEEEEEECC
NVDNFFAETESVGFNPGVLVPGIQPSEDKMLQGRLFSYSDTQRHRIGPNYLQLPINCPFA
CHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHCEEECCCCCHHHCCCCCEEEEECCCCHH
QVANNQRDGAMPFKQQTSPVNYEPNRYEDAPKPNADYIETPQPITGVTGRQKIEKTNDFG
HHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
QAGEVYRRYSQEEKDALIRNLVAHIKEVRHEKTVLLLICNFYRADRELGERLSNELNVDL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHCCCCH
APFLNQMSN
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]