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The map label for this gene is resD [H]

Identifier: 229918206

GI number: 229918206

Start: 2447323

End: 2447685

Strand: Direct

Name: resD [H]

Synonym: EAT1b_2486

Alternate gene names: 229918206

Gene position: 2447323-2447685 (Clockwise)

Preceding gene: 229918205

Following gene: 229918207

Centisome position: 81.58

GC content: 43.8

Gene sequence:

>363_bases
ATGGTTAAAATCTTACTTGCGGAAGACGAAGAAGTGCTACGCATGCTTGTTATGGATACATTAGAAGATGAAGGATATGA
CATCGACGAGGCACAAGATGGAATTGAGGCCTATCGATTGATTGAAGAAAATGAATATGATTTGGTCATTGTGGATCATA
TGATGCCCGGCATGACAGGGCTTGAAGTGATTGAAAAAGTACGGAAGTTACCAGGGCGGCAAGAGACGAAAGTGATGATG
TTGACGGCGAAAAGCCAACAATCTGACCGTGATTGCGCGAACGAGATTGGTGTCGACTACTTCATTTCTAAACCGTTCAG
CCCACTTGAACTCGTCAAAATCATAGGAGGCATCGTGAAGTGA

Upstream 100 bases:

>100_bases
CAAAAGACGTACGAGATGAGTTTCGTACGTCTTTTTATTTTGTGTAACAATTACAAATCCGTTAAAATAAAAAAATGGGA
TAAAAAATGGAGGAACAATT

Downstream 100 bases:

>100_bases
AAAGGTGGTTTAAACAAAAACTCGGACGCGACATCATGGTCGTCCTTTATTCCTTCCTCGTCATTGCGTTGGTCGGATCG
GCATTGACATATGTCTACAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MVKILLAEDEEVLRMLVMDTLEDEGYDIDEAQDGIEAYRLIEENEYDLVIVDHMMPGMTGLEVIEKVRKLPGRQETKVMM
LTAKSQQSDRDCANEIGVDYFISKPFSPLELVKIIGGIVK

Sequences:

>Translated_120_residues
MVKILLAEDEEVLRMLVMDTLEDEGYDIDEAQDGIEAYRLIEENEYDLVIVDHMMPGMTGLEVIEKVRKLPGRQETKVMM
LTAKSQQSDRDCANEIGVDYFISKPFSPLELVKIIGGIVK
>Mature_120_residues
MVKILLAEDEEVLRMLVMDTLEDEGYDIDEAQDGIEAYRLIEENEYDLVIVDHMMPGMTGLEVIEKVRKLPGRQETKVMM
LTAKSQQSDRDCANEIGVDYFISKPFSPLELVKIIGGIVK

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=36.4406779661017, Blast_Score=80, Evalue=5e-17,
Organism=Escherichia coli, GI1790863, Length=109, Percent_Identity=38.5321100917431, Blast_Score=76, Evalue=7e-16,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=31.3559322033898, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI87082012, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=111, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=112, Percent_Identity=33.9285714285714, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=111, Percent_Identity=29.7297297297297, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=35, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13651; Mature: 13651

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILLAEDEEVLRMLVMDTLEDEGYDIDEAQDGIEAYRLIEENEYDLVIVDHMMPGMTG
CEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHH
LEVIEKVRKLPGRQETKVMMLTAKSQQSDRDCANEIGVDYFISKPFSPLELVKIIGGIVK
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVKILLAEDEEVLRMLVMDTLEDEGYDIDEAQDGIEAYRLIEENEYDLVIVDHMMPGMTG
CEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHH
LEVIEKVRKLPGRQETKVMMLTAKSQQSDRDCANEIGVDYFISKPFSPLELVKIIGGIVK
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]