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The map label for this gene is yfhA [H]

Identifier: 229917830

GI number: 229917830

Start: 2060666

End: 2061712

Strand: Direct

Name: yfhA [H]

Synonym: EAT1b_2108

Alternate gene names: 229917830

Gene position: 2060666-2061712 (Clockwise)

Preceding gene: 229917829

Following gene: 229917831

Centisome position: 68.69

GC content: 52.91

Gene sequence:

>1047_bases
ATGAAAACCTATCGCTTTCGAAAAGGTCCTGTCTCGTTCACGCTCCGAAAGCGTGAAATCGAGTTGGCGCTTCTACTTGT
CGTCGGATTGCTCGTGTCGATTTATTTCGGGCTCGCCATCGGTGACACATTCCTCCGTCCCGCCTCACTCGCTGCCTTGT
TCATTGGAGCAGGGGATGCATTCGAGCAACTCGTCGTCTTCGAGTTTCGGATGCCACGTGTGTTGATGGCAATCACCGCC
GGCGCGAGTCTCGCTGTCAGTGGTCACTTGTTACAACTGACAATCAAAAACGAATTGGCATCCCCGGAGATTTTTGGGAT
TGTCGGTGGCGCAGGGGTTGCGACGGCCACGTTCTTCACCGTTTTCTCCGATGAGCGAACGAATCAGCTGTCAGTGCCGC
TCGCCTATATCCCCATCGCTTCGTTCCTTGGGGCGATTGTTGTCGGGATGTTCCTCTTCTATTTGTTGAAACGTGGAGTC
CCACCTGTCCGGCTTGCACTTGTCGGGATTGGGATCAGCATTTTCTCGCAAGGAATCGTTCAGTTCATGATGCTCGCCTC
GAACGTCTACCGGAAGAACGATATCCAACAATGGCTCACCGGTACCGTCTACGCCGCGACGTGGAATCAATTGAAGATCA
TGATTCCGTTCGTCCTTCTCTTTTTACTGGCAGCCTTCTTGATTGAACGTCATGTTCGTCCGCTCCATATCAGTGAAGCG
ACAGCGACGAGCATCGGCGTACCGGTACGAGGGATTCAGCGTGGGACGTTGTTGCTTTCCTGTTTACTCGCCGGAATCGG
TGTCGCCTTTGTCGGTGCAATCGGGTTTGTCGGGTTGATGGCACCTCATATCGCCCGACAAGGATTGAAGCTCCCTTACA
TCTGGGCGACGCTACTTGTAGGGGCGACGATTGTCGTGTTGGCGGACGTACTCGCTCGGACGATTTTTTATCCGTATGAA
CTACGAACCGGCGTGATGACGGCTGTCATCGGAGCTCCGTATTTCTTCTATTTACTTCGACGGATGATGAAAGGAAGCAT
GAGATGA

Upstream 100 bases:

>100_bases
TCCTGTTCCCACGCGAAGTGACCGTTGGGGTCGTACTCGCCGTCATCGGTGGGGCATTCTTCATCTATCTCGTCAGTGTC
AGACAAGGAGTCTTCAAATC

Downstream 100 bases:

>100_bases
ACACATTTGATTTGAACCACGTAACCATCGGATATGAACAGAAGACGGTGCTCGAACAATTATCGTTCTCCATCCCACAT
GGGAAAATCACCGTCCTTCT

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKTYRFRKGPVSFTLRKREIELALLLVVGLLVSIYFGLAIGDTFLRPASLAALFIGAGDAFEQLVVFEFRMPRVLMAITA
GASLAVSGHLLQLTIKNELASPEIFGIVGGAGVATATFFTVFSDERTNQLSVPLAYIPIASFLGAIVVGMFLFYLLKRGV
PPVRLALVGIGISIFSQGIVQFMMLASNVYRKNDIQQWLTGTVYAATWNQLKIMIPFVLLFLLAAFLIERHVRPLHISEA
TATSIGVPVRGIQRGTLLLSCLLAGIGVAFVGAIGFVGLMAPHIARQGLKLPYIWATLLVGATIVVLADVLARTIFYPYE
LRTGVMTAVIGAPYFFYLLRRMMKGSMR

Sequences:

>Translated_348_residues
MKTYRFRKGPVSFTLRKREIELALLLVVGLLVSIYFGLAIGDTFLRPASLAALFIGAGDAFEQLVVFEFRMPRVLMAITA
GASLAVSGHLLQLTIKNELASPEIFGIVGGAGVATATFFTVFSDERTNQLSVPLAYIPIASFLGAIVVGMFLFYLLKRGV
PPVRLALVGIGISIFSQGIVQFMMLASNVYRKNDIQQWLTGTVYAATWNQLKIMIPFVLLFLLAAFLIERHVRPLHISEA
TATSIGVPVRGIQRGTLLLSCLLAGIGVAFVGAIGFVGLMAPHIARQGLKLPYIWATLLVGATIVVLADVLARTIFYPYE
LRTGVMTAVIGAPYFFYLLRRMMKGSMR
>Mature_348_residues
MKTYRFRKGPVSFTLRKREIELALLLVVGLLVSIYFGLAIGDTFLRPASLAALFIGAGDAFEQLVVFEFRMPRVLMAITA
GASLAVSGHLLQLTIKNELASPEIFGIVGGAGVATATFFTVFSDERTNQLSVPLAYIPIASFLGAIVVGMFLFYLLKRGV
PPVRLALVGIGISIFSQGIVQFMMLASNVYRKNDIQQWLTGTVYAATWNQLKIMIPFVLLFLLAAFLIERHVRPLHISEA
TATSIGVPVRGIQRGTLLLSCLLAGIGVAFVGAIGFVGLMAPHIARQGLKLPYIWATLLVGATIVVLADVLARTIFYPYE
LRTGVMTAVIGAPYFFYLLRRMMKGSMR

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=284, Percent_Identity=36.2676056338028, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786804, Length=329, Percent_Identity=31.0030395136778, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790741, Length=306, Percent_Identity=32.6797385620915, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786347, Length=291, Percent_Identity=30.2405498281787, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786805, Length=300, Percent_Identity=31, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788004, Length=299, Percent_Identity=30.1003344481605, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37968; Mature: 37968

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYRFRKGPVSFTLRKREIELALLLVVGLLVSIYFGLAIGDTFLRPASLAALFIGAGDA
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCHH
FEQLVVFEFRMPRVLMAITAGASLAVSGHLLQLTIKNELASPEIFGIVGGAGVATATFFT
HHHHHHHHHHCHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCEEEEECCCHHHHHHHHH
VFSDERTNQLSVPLAYIPIASFLGAIVVGMFLFYLLKRGVPPVRLALVGIGISIFSQGIV
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QFMMLASNVYRKNDIQQWLTGTVYAATWNQLKIMIPFVLLFLLAAFLIERHVRPLHISEA
HHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHH
TATSIGVPVRGIQRGTLLLSCLLAGIGVAFVGAIGFVGLMAPHIARQGLKLPYIWATLLV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GATIVVLADVLARTIFYPYELRTGVMTAVIGAPYFFYLLRRMMKGSMR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTYRFRKGPVSFTLRKREIELALLLVVGLLVSIYFGLAIGDTFLRPASLAALFIGAGDA
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCHH
FEQLVVFEFRMPRVLMAITAGASLAVSGHLLQLTIKNELASPEIFGIVGGAGVATATFFT
HHHHHHHHHHCHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCEEEEECCCHHHHHHHHH
VFSDERTNQLSVPLAYIPIASFLGAIVVGMFLFYLLKRGVPPVRLALVGIGISIFSQGIV
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QFMMLASNVYRKNDIQQWLTGTVYAATWNQLKIMIPFVLLFLLAAFLIERHVRPLHISEA
HHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHH
TATSIGVPVRGIQRGTLLLSCLLAGIGVAFVGAIGFVGLMAPHIARQGLKLPYIWATLLV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GATIVVLADVLARTIFYPYELRTGVMTAVIGAPYFFYLLRRMMKGSMR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]