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The map label for this gene is alr [H]

Identifier: 229917795

GI number: 229917795

Start: 2024441

End: 2025517

Strand: Direct

Name: alr [H]

Synonym: EAT1b_2073

Alternate gene names: 229917795

Gene position: 2024441-2025517 (Clockwise)

Preceding gene: 229917794

Following gene: 229917796

Centisome position: 67.48

GC content: 52.83

Gene sequence:

>1077_bases
ATGTTTCGTCCTAGTCGAATCGAGATTGATCGGGCGGCCATCGCCCATAATATAAAAGAATTAACGAGACGGATTCCGCA
GGACCTCATGGCGGTCGTCAAAGCAAATGCCTACGGACACGGGGCCGTCGAAGTAGCGAAGATCGCCCTGGAGAACGGAG
CGACGATGCTCGGGGTCGCGTTACTCGAGGAAGCGCTCGAACTCCGCGATGCGGGAATCGAAGCACCGATTCTCGTCATG
GAAGCGCAATTCCCTGAATATGCCGGAGTGGCGGCAGAACAGGGGATCACGTTGTCCGTATTTTCTGCCGAATGGTTACG
AGAGGCAGCTCCATATATAGAAGAAAAGCCGTTGGCGGTTCATATCAAAGTCGATACCGGGATGGGACGCCTCGGACTTC
GTACCCGTGAACAGTTGAATGCCTTACTTGAAGAAGCGACCGATTCTTTTGTGGTGGAAGGAATCTATACCCACTTCGCA
ACGGCGGATGAGCTCGATAGCAATCTGTATTATACACAGCAAGAGCGGTTCGAGCGTTTGATGGATGGTCTCCACGAGCG
GTTCCGCTATATCCATACGTCGAACTCGGCCGGTGCGATCCGGATGGCCGGACAAGACGTTCCTTATAATCTGGTTCGTG
TCGGCATCGCGCTTTATGGGTTATATCCATCACATGAGATGGAGACGTTCTATTCATTCCTGCGTCCGGCATTCACGTTA
AAAAGTCAGCTCATGCAGGTGAAGCGGCTAGAGGCAGGTCAGACCATCAGTTACGGTGCGACGTATACAACGTCAGCCGA
TGAATGGATTGGTACCGTTCCGGTCGGATATGCGGACGGGTGGTTACGAAAGGCGAGCGGATTTGAAGTGGAGGTCAATG
GGATTCGTTGTCCGATCGTGGGACGCGTCTGTATGGACCGTTTCATGATCCGGCTTCCAAAAGAGTTTCCGGTCGGGACG
GACGTGACCCTTGTCGGTGGAAACGTCGCCATTGATGAACTCGCCTCATATCTTGGGACGATCAACTATGAGATCGTTTG
CCAATTCACGAGCCGATTGCCACGTCTTTATGTGTGA

Upstream 100 bases:

>100_bases
CCTGTCATGACCGCGCCGTTTGTGGGGAAGATCCATGTCAGCATCAGCCATAGTCAAACATACGCCATCGCACAAGTCAT
CTTAGAAGAGGAGGGACATC

Downstream 100 bases:

>100_bases
ATCATAAATCGTGTGAAATTATCTGAATTCTTTCTCGATTTCTCTATATTTTCCCATTCCCGCGTGTTATATTGATAAAG
AACGCGGGAGAATTTCCGCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFRPSRIEIDRAAIAHNIKELTRRIPQDLMAVVKANAYGHGAVEVAKIALENGATMLGVALLEEALELRDAGIEAPILVM
EAQFPEYAGVAAEQGITLSVFSAEWLREAAPYIEEKPLAVHIKVDTGMGRLGLRTREQLNALLEEATDSFVVEGIYTHFA
TADELDSNLYYTQQERFERLMDGLHERFRYIHTSNSAGAIRMAGQDVPYNLVRVGIALYGLYPSHEMETFYSFLRPAFTL
KSQLMQVKRLEAGQTISYGATYTTSADEWIGTVPVGYADGWLRKASGFEVEVNGIRCPIVGRVCMDRFMIRLPKEFPVGT
DVTLVGGNVAIDELASYLGTINYEIVCQFTSRLPRLYV

Sequences:

>Translated_358_residues
MFRPSRIEIDRAAIAHNIKELTRRIPQDLMAVVKANAYGHGAVEVAKIALENGATMLGVALLEEALELRDAGIEAPILVM
EAQFPEYAGVAAEQGITLSVFSAEWLREAAPYIEEKPLAVHIKVDTGMGRLGLRTREQLNALLEEATDSFVVEGIYTHFA
TADELDSNLYYTQQERFERLMDGLHERFRYIHTSNSAGAIRMAGQDVPYNLVRVGIALYGLYPSHEMETFYSFLRPAFTL
KSQLMQVKRLEAGQTISYGATYTTSADEWIGTVPVGYADGWLRKASGFEVEVNGIRCPIVGRVCMDRFMIRLPKEFPVGT
DVTLVGGNVAIDELASYLGTINYEIVCQFTSRLPRLYV
>Mature_358_residues
MFRPSRIEIDRAAIAHNIKELTRRIPQDLMAVVKANAYGHGAVEVAKIALENGATMLGVALLEEALELRDAGIEAPILVM
EAQFPEYAGVAAEQGITLSVFSAEWLREAAPYIEEKPLAVHIKVDTGMGRLGLRTREQLNALLEEATDSFVVEGIYTHFA
TADELDSNLYYTQQERFERLMDGLHERFRYIHTSNSAGAIRMAGQDVPYNLVRVGIALYGLYPSHEMETFYSFLRPAFTL
KSQLMQVKRLEAGQTISYGATYTTSADEWIGTVPVGYADGWLRKASGFEVEVNGIRCPIVGRVCMDRFMIRLPKEFPVGT
DVTLVGGNVAIDELASYLGTINYEIVCQFTSRLPRLYV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=362, Percent_Identity=36.4640883977901, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=33.0601092896175, Blast_Score=158, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39902; Mature: 39902

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPSRIEIDRAAIAHNIKELTRRIPQDLMAVVKANAYGHGAVEVAKIALENGATMLGVA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
LLEEALELRDAGIEAPILVMEAQFPEYAGVAAEQGITLSVFSAEWLREAAPYIEEKPLAV
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCCEEEEECHHHHHHHCCCCCCCCEEE
HIKVDTGMGRLGLRTREQLNALLEEATDSFVVEGIYTHFATADELDSNLYYTQQERFERL
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECHHHHHHHH
MDGLHERFRYIHTSNSAGAIRMAGQDVPYNLVRVGIALYGLYPSHEMETFYSFLRPAFTL
HHHHHHHHHEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KSQLMQVKRLEAGQTISYGATYTTSADEWIGTVPVGYADGWLRKASGFEVEVNGIRCPIV
HHHHHHHHHHCCCCEEECCCEEECCHHHHCCCCCCCCCCCHHCCCCCCEEEECCEECCHH
GRVCMDRFMIRLPKEFPVGTDVTLVGGNVAIDELASYLGTINYEIVCQFTSRLPRLYV
HHHHHHHHHHHCCCCCCCCCCEEEECCCEEHHHHHHHHCCCCCEEEEEEHHCCCCCCC
>Mature Secondary Structure
MFRPSRIEIDRAAIAHNIKELTRRIPQDLMAVVKANAYGHGAVEVAKIALENGATMLGVA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
LLEEALELRDAGIEAPILVMEAQFPEYAGVAAEQGITLSVFSAEWLREAAPYIEEKPLAV
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCCEEEEECHHHHHHHCCCCCCCCEEE
HIKVDTGMGRLGLRTREQLNALLEEATDSFVVEGIYTHFATADELDSNLYYTQQERFERL
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECHHHHHHHH
MDGLHERFRYIHTSNSAGAIRMAGQDVPYNLVRVGIALYGLYPSHEMETFYSFLRPAFTL
HHHHHHHHHEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KSQLMQVKRLEAGQTISYGATYTTSADEWIGTVPVGYADGWLRKASGFEVEVNGIRCPIV
HHHHHHHHHHCCCCEEECCCEEECCHHHHCCCCCCCCCCCHHCCCCCCEEEECCEECCHH
GRVCMDRFMIRLPKEFPVGTDVTLVGGNVAIDELASYLGTINYEIVCQFTSRLPRLYV
HHHHHHHHHHHCCCCCCCCCCEEEECCCEEHHHHHHHHCCCCCEEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10080917 [H]