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The map label for this gene is moaB [H]

Identifier: 229917635

GI number: 229917635

Start: 1874495

End: 1874998

Strand: Direct

Name: moaB [H]

Synonym: EAT1b_1911

Alternate gene names: 229917635

Gene position: 1874495-1874998 (Clockwise)

Preceding gene: 229917634

Following gene: 229917636

Centisome position: 62.49

GC content: 53.17

Gene sequence:

>504_bases
ATGCAAGCACACAACCATGTACATCAAAACACACAGCGTGTCCGGGCAGCGATTTTGACGATCTCGGATACGCGAACACT
CGATACGGACGTGTCTGGCGAACATATTTGTACGCTATTAAAAGAAGAAGCACATACGGTCACATACCGCGAAATCACGA
AAGATGACTCATTTGAAATCGAAGCGGCCGTCAGACGAATGGTCGACGAAAAAATGGACGTCATCTTGACGACCGGGGGA
ACGGGCATCACGAAACGGGACGTCACCATTGAGACGATTCGACCGCTGCTTGACCGAGAAATGGTCGGCTTCGGCGAGTT
GTTCCGTTATGTCAGCTTCACGGAAGATATCGGACCGGCGGCGATGTTGTCGCGAGCTTTAGCAGGACGCATCGGGGATA
CGATCATCTTTTCGATGCCAGGGTCGCGAGGCGCCGTCGACTTGGCGATGACTCGCTTGATTCTTCCCGAGCTCTCCCAT
ATCGTCTGGGAAGCGACGCGATGA

Upstream 100 bases:

>100_bases
TATGGGAAGTACGGGAAGACCGCTATTCGGAAGAACGGTCGCGAACTGGGAGTCGGACGCGAAACCGAATTGAAATGAGT
TATATCGGAGGATGAAGACG

Downstream 100 bases:

>100_bases
TCGGCATCGTCTTGGCAGGCGGAAAATCGCGCCGGTTCGGATCCCCTAAATGGCAAGCCTGTTATGAGGACATCTCGTTT
GAAGAGCGGGCGCGACAGAC

Product: molybdenum cofactor synthesis domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MQAHNHVHQNTQRVRAAILTISDTRTLDTDVSGEHICTLLKEEAHTVTYREITKDDSFEIEAAVRRMVDEKMDVILTTGG
TGITKRDVTIETIRPLLDREMVGFGELFRYVSFTEDIGPAAMLSRALAGRIGDTIIFSMPGSRGAVDLAMTRLILPELSH
IVWEATR

Sequences:

>Translated_167_residues
MQAHNHVHQNTQRVRAAILTISDTRTLDTDVSGEHICTLLKEEAHTVTYREITKDDSFEIEAAVRRMVDEKMDVILTTGG
TGITKRDVTIETIRPLLDREMVGFGELFRYVSFTEDIGPAAMLSRALAGRIGDTIIFSMPGSRGAVDLAMTRLILPELSH
IVWEATR
>Mature_167_residues
MQAHNHVHQNTQRVRAAILTISDTRTLDTDVSGEHICTLLKEEAHTVTYREITKDDSFEIEAAVRRMVDEKMDVILTTGG
TGITKRDVTIETIRPLLDREMVGFGELFRYVSFTEDIGPAAMLSRALAGRIGDTIIFSMPGSRGAVDLAMTRLILPELSH
IVWEATR

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=164, Percent_Identity=34.7560975609756, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI10880983, Length=164, Percent_Identity=34.7560975609756, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=42.0689655172414, Blast_Score=110, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17136978, Length=159, Percent_Identity=36.4779874213836, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638841, Length=159, Percent_Identity=36.4779874213836, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18668; Mature: 18668

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAHNHVHQNTQRVRAAILTISDTRTLDTDVSGEHICTLLKEEAHTVTYREITKDDSFEI
CCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHEEHHHHHCCCCCCHH
EAAVRRMVDEKMDVILTTGGTGITKRDVTIETIRPLLDREMVGFGELFRYVSFTEDIGPA
HHHHHHHHHHHHCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AMLSRALAGRIGDTIIFSMPGSRGAVDLAMTRLILPELSHIVWEATR
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQAHNHVHQNTQRVRAAILTISDTRTLDTDVSGEHICTLLKEEAHTVTYREITKDDSFEI
CCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHEEHHHHHCCCCCCHH
EAAVRRMVDEKMDVILTTGGTGITKRDVTIETIRPLLDREMVGFGELFRYVSFTEDIGPA
HHHHHHHHHHHHCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AMLSRALAGRIGDTIIFSMPGSRGAVDLAMTRLILPELSHIVWEATR
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]