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The map label for this gene is bglH [H]

Identifier: 229917604

GI number: 229917604

Start: 1846345

End: 1847790

Strand: Direct

Name: bglH [H]

Synonym: EAT1b_1879

Alternate gene names: 229917604

Gene position: 1846345-1847790 (Clockwise)

Preceding gene: 229917603

Following gene: 229917608

Centisome position: 61.55

GC content: 45.57

Gene sequence:

>1446_bases
ATGAAACAAGTATCAAGTGATTTTCTATGGGGCGGGGCCACTGCGGCCAATCAACTAGAGGGCGGTTATCAGGAAGGCGG
TAAAGGACTTTCGATTGCAGACGTGATGCCAGGTGGGAAACAGCGAATGAAAATCATTCATGACCCAGCGTTTGATTTTG
AGTTACATGATGAATATTCATATCCGAACCATGAAGGAATTGACTTCTATCATCGTTACAAAGAAGATATCGCCCTTTTT
AAGGAAATGGGATTCAAGACGTTCCGTATGTCGATTGCCTGGTCACGAATTTTCCCGAACGGCGATGAAGTGGAACCGAA
TGAGGAGGGACTCCAATTCTATGATCGTGTCATCAATGAGTTGGTCGCCCAAGGCATTGAACCACTCGTGACGATTTCTC
ATTATGAGATGCCCTTACATCTTGCGAAGCATTATGGAGGGTGGCGAGACCGTCGCTTAGTCACCTATTTCGAACGATAC
AGCCGCGTCTTGTTCGAACGTTATAAAGGGAAGGTCAAATATTGGTTGACGTTCAATGAGATCAACGGAGCGCAGTTCAT
GCCGATGCTCAGTCTCGGAATCGCAGTTCGAGAAGAAGAGAACACATTACAACTTACGTATCAAGGACTTCATCACCAAC
TGGTCGCAAGTGCACTCGCGACGAAAGCGGCCCGCGAGATTGACCCATCGATGCAAATCGGATGTATGCTGATTGCAGCT
CCGGTTTATCCATACAGCTCAAACCCGGACGATGTTTGGTATGCCCACGATGCTGAGCGGATGATGAACTTCTTCTGTGG
AGATGTTCACGTACGCGGGAAATACCCAAGCTTTGCAAAACGCTTTTTCCAAGAGAACGGCATTGAACTTGAAATGGAAG
ATGGCGACCTTGAAATCCTAAAAGAAAATACAGTTGATTTCTTTTCGCTCAGTTATTATATGTCGCGCACTGAAAAGGCT
GAAAAAGACCAGAATGAAGCGGAAGGTAATATCATGAGTGGGGTCAAAAATCCATACTTACAAGCGAGCGACTGGGGATG
GGAGATTGACCCGACCGGACTTCGTGTCATCTTAAACAAATTATATGAGCGTTATGAGCTTCCATTATTCATCGTTGAGA
ATGGATTAGGTGCATATGATCAAGTCGAGTCGGACGGAACGATTCATGATCACTATCGGATTGATTACTTACGTGATCAT
TTGAAAGGGATGATAGACGCAATCGAAGATGGTGTCGAAGTGATGGGGTACACGAGTTGGGGCTGTATCGATTTAGTGAG
TGCTTCGACAGGCGAGTACAGCAAACGGTATGGTTTCATTTATGTGGATCGACATGACGACGGTACCGGTACGTTAGAAC
GAAAACGGAAAGAATCATTCTTCTGGTATCAAGAGGTGATTCGTTCGCAAGGCGCGAGCTTATATGAAGAGGAATCAGTC
AAATGA

Upstream 100 bases:

>100_bases
AATACCGATCATTATTTAGACGTATTGCCAACTTACACAGGAACGGTAGAAGCGAATCATGGCGTATTGCGAGTCATTGT
ATAACAAAGGAGGAGACAAC

Downstream 100 bases:

>100_bases
AAAAGGCGGCCGCGGCCGCTTTTTTTCATGCTTTCGTAATCTTTCGCAATAAGATGATTGCGAGGCTAACGCCCCCGGCA
ATCAACATATACAAGACAAT

Product: glycoside hydrolase family 1

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MKQVSSDFLWGGATAANQLEGGYQEGGKGLSIADVMPGGKQRMKIIHDPAFDFELHDEYSYPNHEGIDFYHRYKEDIALF
KEMGFKTFRMSIAWSRIFPNGDEVEPNEEGLQFYDRVINELVAQGIEPLVTISHYEMPLHLAKHYGGWRDRRLVTYFERY
SRVLFERYKGKVKYWLTFNEINGAQFMPMLSLGIAVREEENTLQLTYQGLHHQLVASALATKAAREIDPSMQIGCMLIAA
PVYPYSSNPDDVWYAHDAERMMNFFCGDVHVRGKYPSFAKRFFQENGIELEMEDGDLEILKENTVDFFSLSYYMSRTEKA
EKDQNEAEGNIMSGVKNPYLQASDWGWEIDPTGLRVILNKLYERYELPLFIVENGLGAYDQVESDGTIHDHYRIDYLRDH
LKGMIDAIEDGVEVMGYTSWGCIDLVSASTGEYSKRYGFIYVDRHDDGTGTLERKRKESFFWYQEVIRSQGASLYEEESV
K

Sequences:

>Translated_481_residues
MKQVSSDFLWGGATAANQLEGGYQEGGKGLSIADVMPGGKQRMKIIHDPAFDFELHDEYSYPNHEGIDFYHRYKEDIALF
KEMGFKTFRMSIAWSRIFPNGDEVEPNEEGLQFYDRVINELVAQGIEPLVTISHYEMPLHLAKHYGGWRDRRLVTYFERY
SRVLFERYKGKVKYWLTFNEINGAQFMPMLSLGIAVREEENTLQLTYQGLHHQLVASALATKAAREIDPSMQIGCMLIAA
PVYPYSSNPDDVWYAHDAERMMNFFCGDVHVRGKYPSFAKRFFQENGIELEMEDGDLEILKENTVDFFSLSYYMSRTEKA
EKDQNEAEGNIMSGVKNPYLQASDWGWEIDPTGLRVILNKLYERYELPLFIVENGLGAYDQVESDGTIHDHYRIDYLRDH
LKGMIDAIEDGVEVMGYTSWGCIDLVSASTGEYSKRYGFIYVDRHDDGTGTLERKRKESFFWYQEVIRSQGASLYEEESV
K
>Mature_481_residues
MKQVSSDFLWGGATAANQLEGGYQEGGKGLSIADVMPGGKQRMKIIHDPAFDFELHDEYSYPNHEGIDFYHRYKEDIALF
KEMGFKTFRMSIAWSRIFPNGDEVEPNEEGLQFYDRVINELVAQGIEPLVTISHYEMPLHLAKHYGGWRDRRLVTYFERY
SRVLFERYKGKVKYWLTFNEINGAQFMPMLSLGIAVREEENTLQLTYQGLHHQLVASALATKAAREIDPSMQIGCMLIAA
PVYPYSSNPDDVWYAHDAERMMNFFCGDVHVRGKYPSFAKRFFQENGIELEMEDGDLEILKENTVDFFSLSYYMSRTEKA
EKDQNEAEGNIMSGVKNPYLQASDWGWEIDPTGLRVILNKLYERYELPLFIVENGLGAYDQVESDGTIHDHYRIDYLRDH
LKGMIDAIEDGVEVMGYTSWGCIDLVSASTGEYSKRYGFIYVDRHDDGTGTLERKRKESFFWYQEVIRSQGASLYEEESV
K

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=486, Percent_Identity=29.0123456790123, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI110681710, Length=494, Percent_Identity=28.9473684210526, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI13273313, Length=488, Percent_Identity=26.0245901639344, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI28376633, Length=486, Percent_Identity=27.1604938271605, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI24497614, Length=482, Percent_Identity=27.1784232365145, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789070, Length=475, Percent_Identity=55.3684210526316, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI2367174, Length=477, Percent_Identity=55.7651991614256, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=53.9748953974895, Blast_Score=512, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=29.1497975708502, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17539390, Length=501, Percent_Identity=27.5449101796407, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356577, Length=474, Percent_Identity=27.6371308016878, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55631; Mature: 55631

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVSSDFLWGGATAANQLEGGYQEGGKGLSIADVMPGGKQRMKIIHDPAFDFELHDEYS
CCCCCCCCCCCCCCHHHHHCCCHHCCCCCCEEEECCCCCHHHHEEEECCCCCEEECCCCC
YPNHEGIDFYHRYKEDIALFKEMGFKTFRMSIAWSRIFPNGDEVEPNEEGLQFYDRVINE
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LVAQGIEPLVTISHYEMPLHLAKHYGGWRDRRLVTYFERYSRVLFERYKGKVKYWLTFNE
HHHCCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
INGAQFMPMLSLGIAVREEENTLQLTYQGLHHQLVASALATKAAREIDPSMQIGCMLIAA
CCCCHHHHHHHHCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCEEEEEE
PVYPYSSNPDDVWYAHDAERMMNFFCGDVHVRGKYPSFAKRFFQENGIELEMEDGDLEIL
CCCCCCCCCCCEEEECCHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCEEEECCCCEEEE
KENTVDFFSLSYYMSRTEKAEKDQNEAEGNIMSGVKNPYLQASDWGWEIDPTGLRVILNK
ECCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCCCCEEECCCCCEECCHHHHHHHHH
LYERYELPLFIVENGLGAYDQVESDGTIHDHYRIDYLRDHLKGMIDAIEDGVEVMGYTSW
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHEEECCCC
GCIDLVSASTGEYSKRYGFIYVDRHDDGTGTLERKRKESFFWYQEVIRSQGASLYEEESV
CHHEEECCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
K
C
>Mature Secondary Structure
MKQVSSDFLWGGATAANQLEGGYQEGGKGLSIADVMPGGKQRMKIIHDPAFDFELHDEYS
CCCCCCCCCCCCCCHHHHHCCCHHCCCCCCEEEECCCCCHHHHEEEECCCCCEEECCCCC
YPNHEGIDFYHRYKEDIALFKEMGFKTFRMSIAWSRIFPNGDEVEPNEEGLQFYDRVINE
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LVAQGIEPLVTISHYEMPLHLAKHYGGWRDRRLVTYFERYSRVLFERYKGKVKYWLTFNE
HHHCCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
INGAQFMPMLSLGIAVREEENTLQLTYQGLHHQLVASALATKAAREIDPSMQIGCMLIAA
CCCCHHHHHHHHCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCEEEEEE
PVYPYSSNPDDVWYAHDAERMMNFFCGDVHVRGKYPSFAKRFFQENGIELEMEDGDLEIL
CCCCCCCCCCCEEEECCHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCEEEECCCCEEEE
KENTVDFFSLSYYMSRTEKAEKDQNEAEGNIMSGVKNPYLQASDWGWEIDPTGLRVILNK
ECCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCCCCEEECCCCCEECCHHHHHHHHH
LYERYELPLFIVENGLGAYDQVESDGTIHDHYRIDYLRDHLKGMIDAIEDGVEVMGYTSW
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHEEECCCC
GCIDLVSASTGEYSKRYGFIYVDRHDDGTGTLERKRKESFFWYQEVIRSQGASLYEEESV
CHHEEECCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]