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The map label for this gene is htpG [H]

Identifier: 229917537

GI number: 229917537

Start: 1777515

End: 1779383

Strand: Reverse

Name: htpG [H]

Synonym: EAT1b_1812

Alternate gene names: 229917537

Gene position: 1779383-1777515 (Counterclockwise)

Preceding gene: 229917538

Following gene: 229917536

Centisome position: 59.31

GC content: 48.31

Gene sequence:

>1869_bases
ATGACAAAGAAACAGTTTCAAACGGAATCGAAACGAATTTTAGAGTTGATGGTCCACTCAATTTATACACATAAGGACAT
CTTCCTGCGTGAGCTCATCTCGAACGCGAGTGATGCCATCGACAAGATGTATTATCGTGCCCTCTCAGACGAAAGCATCG
AGTTCAACAAAGACGATTACTTCATCAAAATTGAACTCGACAAAGAAGCACGGACGATTACGATTCGCGATACAGGGATT
GGGATGACAGAAGAAGAACTCGAAACAAACCTCGGAATCATCGCCAAGAGCGGTTCACTCGCCATGAAACAGGCAACGAA
GATGGAAGAAGACCATAGCCTCATCGGACAATTCGGGGTCGGATTCTATTCCGCGTTCATGGTCGCTGACCGTGTGACCG
TGCGGACTCGTTCGATTGACAGTGAACAAGGATACGTATGGGAGTCAGAAGGCACAGACGGCTATTCGATCGAGCCGACA
GACAAGGCGGGCATCGGTACAGAAATCACGCTCCACTTGAAAGCAGACACAGAAGATGATATGTACTCGTCATTCCTTGA
AGAATACGAGATTCGCTCGCTCATCAAGAAACATTCGGATTTCATCCGTTACCCGATCAAACTCGATGTGACGAAGCATC
GTCAAAAAGAGGACTCGGAAGAATACGAGGATTATCAAGAAGAAGAGACCGTCAACAGCATGGTGCCGATTTGGCGGAAG
CGGAAGAGCGAACTGACCGACGAAGATTACAAAGCGTTCTATCACGAGAAACGCTACGGCTTTGATGAGCCGCTCAAGCA
CCTTCATTTGAACGTCGACGGGACAATTCGTTATCAATCGATTCTCTATATCCCATCAACGGTTCCATTCGATTACTACA
CAAAAGAATTTGAGAAAGGGCTCGAGCTCTACTCGAATGGCGTGTTGATCATGGAGAAGTCACCTGACCTCTTGCCAGAC
TACTTCGGCTTCGTCAAAGGGATGGTCGACTCAGAAGACCTCTCCCTTAACATTTCCCGTGAAATGTTACAGCAGGACCG
CCAACTTCGCGTGATCGCCAAAAACGTGAAGTCCAAAATCAAAGGGATGCTCGAGAAGATGCTCCAAAACGAGCGTGAGG
ATTACGAGAAGTTCTATGAGTCGTTCGGTCGTCAATTGAAGTTCGGCGTGTATGATCAGTTCGGCGCAGCCAAAGACGAA
TTGAAAGACTTGATTCTGTTCCATTCTTCTCACGAGAAGAAACTCGTCTCGCTCAAAGAGTACGTCGAGCGGATGAAAGA
AGATCAGAAGTATATCTACTATGCGACAGGCGAATCGATTCATCGCATCGACCTCTTGCCACAAGCAGAACGCTTGAAAG
AAGAGGGATACGAGATCCTCTACTTCACAGAAGAGATTGACGAGTTCGCCATCAAGATGCTTCAGTCGTATGACGACAAA
GAGTTCAAATCGATTGCGAGCGGCGACCTCGGTCTCGATGACGCGGAAGCGAAATCGCTCAACGACGATAACCAAGACTT
ATTCGCCTTCATGAAAGAAGAGCTCGGAGACCGCGTCAAAGAAGTGCGTGCCTCGACACGCCTTAAGTCACATCCGGTCT
GCTTGACGGTCGCGGGTGACGTCTCAATCGAGATGGAGAAGATTTTGAACGCGATGCCAAACGGCGGCGGCATGAAAGCG
GAGAAAGTACTCGAGGTGAACGCCGACCACGCCATCTTCCAAACGCTCCAACGTGTGTATAAAGAAGATGAAGCGAAAGC
GAAACAGTATACAGACCTCTTGTATCAACAAGCCCTCCTCATTGAAGGGTTGCCGATTGAAGATCCGGTAGCGTATTCGA
ATGCGGTTTGTGCGTTGATGGCGGAGTGA

Upstream 100 bases:

>100_bases
TAAAATCCGGTTGACATCTTCCTAATTTTTAGGATAATCAATAGTGTTAGCACTCTTTATAAGAGAGTGCCAAAATATAG
ACATTAAAGGGAGAACGATC

Downstream 100 bases:

>100_bases
CGGTGAAGGCAGAGGGCAACCTCTGTCTTTTTTTATTTAAATAAAAACATGATACACTTTTAGTAAATGCAAATCTTGGA
AACGAGGTGCTCTTATGCTG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MTKKQFQTESKRILELMVHSIYTHKDIFLRELISNASDAIDKMYYRALSDESIEFNKDDYFIKIELDKEARTITIRDTGI
GMTEEELETNLGIIAKSGSLAMKQATKMEEDHSLIGQFGVGFYSAFMVADRVTVRTRSIDSEQGYVWESEGTDGYSIEPT
DKAGIGTEITLHLKADTEDDMYSSFLEEYEIRSLIKKHSDFIRYPIKLDVTKHRQKEDSEEYEDYQEEETVNSMVPIWRK
RKSELTDEDYKAFYHEKRYGFDEPLKHLHLNVDGTIRYQSILYIPSTVPFDYYTKEFEKGLELYSNGVLIMEKSPDLLPD
YFGFVKGMVDSEDLSLNISREMLQQDRQLRVIAKNVKSKIKGMLEKMLQNEREDYEKFYESFGRQLKFGVYDQFGAAKDE
LKDLILFHSSHEKKLVSLKEYVERMKEDQKYIYYATGESIHRIDLLPQAERLKEEGYEILYFTEEIDEFAIKMLQSYDDK
EFKSIASGDLGLDDAEAKSLNDDNQDLFAFMKEELGDRVKEVRASTRLKSHPVCLTVAGDVSIEMEKILNAMPNGGGMKA
EKVLEVNADHAIFQTLQRVYKEDEAKAKQYTDLLYQQALLIEGLPIEDPVAYSNAVCALMAE

Sequences:

>Translated_622_residues
MTKKQFQTESKRILELMVHSIYTHKDIFLRELISNASDAIDKMYYRALSDESIEFNKDDYFIKIELDKEARTITIRDTGI
GMTEEELETNLGIIAKSGSLAMKQATKMEEDHSLIGQFGVGFYSAFMVADRVTVRTRSIDSEQGYVWESEGTDGYSIEPT
DKAGIGTEITLHLKADTEDDMYSSFLEEYEIRSLIKKHSDFIRYPIKLDVTKHRQKEDSEEYEDYQEEETVNSMVPIWRK
RKSELTDEDYKAFYHEKRYGFDEPLKHLHLNVDGTIRYQSILYIPSTVPFDYYTKEFEKGLELYSNGVLIMEKSPDLLPD
YFGFVKGMVDSEDLSLNISREMLQQDRQLRVIAKNVKSKIKGMLEKMLQNEREDYEKFYESFGRQLKFGVYDQFGAAKDE
LKDLILFHSSHEKKLVSLKEYVERMKEDQKYIYYATGESIHRIDLLPQAERLKEEGYEILYFTEEIDEFAIKMLQSYDDK
EFKSIASGDLGLDDAEAKSLNDDNQDLFAFMKEELGDRVKEVRASTRLKSHPVCLTVAGDVSIEMEKILNAMPNGGGMKA
EKVLEVNADHAIFQTLQRVYKEDEAKAKQYTDLLYQQALLIEGLPIEDPVAYSNAVCALMAE
>Mature_621_residues
TKKQFQTESKRILELMVHSIYTHKDIFLRELISNASDAIDKMYYRALSDESIEFNKDDYFIKIELDKEARTITIRDTGIG
MTEEELETNLGIIAKSGSLAMKQATKMEEDHSLIGQFGVGFYSAFMVADRVTVRTRSIDSEQGYVWESEGTDGYSIEPTD
KAGIGTEITLHLKADTEDDMYSSFLEEYEIRSLIKKHSDFIRYPIKLDVTKHRQKEDSEEYEDYQEEETVNSMVPIWRKR
KSELTDEDYKAFYHEKRYGFDEPLKHLHLNVDGTIRYQSILYIPSTVPFDYYTKEFEKGLELYSNGVLIMEKSPDLLPDY
FGFVKGMVDSEDLSLNISREMLQQDRQLRVIAKNVKSKIKGMLEKMLQNEREDYEKFYESFGRQLKFGVYDQFGAAKDEL
KDLILFHSSHEKKLVSLKEYVERMKEDQKYIYYATGESIHRIDLLPQAERLKEEGYEILYFTEEIDEFAIKMLQSYDDKE
FKSIASGDLGLDDAEAKSLNDDNQDLFAFMKEELGDRVKEVRASTRLKSHPVCLTVAGDVSIEMEKILNAMPNGGGMKAE
KVLEVNADHAIFQTLQRVYKEDEAKAKQYTDLLYQQALLIEGLPIEDPVAYSNAVCALMAE

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=672, Percent_Identity=36.7559523809524, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI154146191, Length=675, Percent_Identity=35.4074074074074, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI153792590, Length=676, Percent_Identity=35.6508875739645, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI4507677, Length=673, Percent_Identity=35.3640416047548, Blast_Score=354, Evalue=2e-97,
Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=32.2274881516588, Blast_Score=327, Evalue=2e-89,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=38.9589905362776, Blast_Score=422, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17559162, Length=657, Percent_Identity=37.4429223744292, Blast_Score=413, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17542208, Length=670, Percent_Identity=34.9253731343284, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI115535205, Length=635, Percent_Identity=32.5984251968504, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI115535167, Length=434, Percent_Identity=35.7142857142857, Blast_Score=244, Evalue=7e-65,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=36.1764705882353, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=35.9467455621302, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI17647529, Length=674, Percent_Identity=37.6854599406528, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=35.3982300884956, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586016, Length=639, Percent_Identity=32.2378716744914, Blast_Score=307, Evalue=2e-83,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72140; Mature: 72009

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKQFQTESKRILELMVHSIYTHKDIFLRELISNASDAIDKMYYRALSDESIEFNKDDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCE
FIKIELDKEARTITIRDTGIGMTEEELETNLGIIAKSGSLAMKQATKMEEDHSLIGQFGV
EEEEEECCCCCEEEEEECCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GFYSAFMVADRVTVRTRSIDSEQGYVWESEGTDGYSIEPTDKAGIGTEITLHLKADTEDD
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
MYSSFLEEYEIRSLIKKHSDFIRYPIKLDVTKHRQKEDSEEYEDYQEEETVNSMVPIWRK
HHHHHHHHHHHHHHHHHHHHHEECCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RKSELTDEDYKAFYHEKRYGFDEPLKHLHLNVDGTIRYQSILYIPSTVPFDYYTKEFEKG
HHHCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCEEEEEEEEEECCCCCCHHHHHHHHHH
LELYSNGVLIMEKSPDLLPDYFGFVKGMVDSEDLSLNISREMLQQDRQLRVIAKNVKSKI
HHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHH
KGMLEKMLQNEREDYEKFYESFGRQLKFGVYDQFGAAKDELKDLILFHSSHEKKLVSLKE
HHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
YVERMKEDQKYIYYATGESIHRIDLLPQAERLKEEGYEILYFTEEIDEFAIKMLQSYDDK
HHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCH
EFKSIASGDLGLDDAEAKSLNDDNQDLFAFMKEELGDRVKEVRASTRLKSHPVCLTVAGD
HHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
VSIEMEKILNAMPNGGGMKAEKVLEVNADHAIFQTLQRVYKEDEAKAKQYTDLLYQQALL
CCEEHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLPIEDPVAYSNAVCALMAE
HCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
TKKQFQTESKRILELMVHSIYTHKDIFLRELISNASDAIDKMYYRALSDESIEFNKDDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCE
FIKIELDKEARTITIRDTGIGMTEEELETNLGIIAKSGSLAMKQATKMEEDHSLIGQFGV
EEEEEECCCCCEEEEEECCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GFYSAFMVADRVTVRTRSIDSEQGYVWESEGTDGYSIEPTDKAGIGTEITLHLKADTEDD
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
MYSSFLEEYEIRSLIKKHSDFIRYPIKLDVTKHRQKEDSEEYEDYQEEETVNSMVPIWRK
HHHHHHHHHHHHHHHHHHHHHEECCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RKSELTDEDYKAFYHEKRYGFDEPLKHLHLNVDGTIRYQSILYIPSTVPFDYYTKEFEKG
HHHCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCEEEEEEEEEECCCCCCHHHHHHHHHH
LELYSNGVLIMEKSPDLLPDYFGFVKGMVDSEDLSLNISREMLQQDRQLRVIAKNVKSKI
HHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHH
KGMLEKMLQNEREDYEKFYESFGRQLKFGVYDQFGAAKDELKDLILFHSSHEKKLVSLKE
HHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
YVERMKEDQKYIYYATGESIHRIDLLPQAERLKEEGYEILYFTEEIDEFAIKMLQSYDDK
HHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCH
EFKSIASGDLGLDDAEAKSLNDDNQDLFAFMKEELGDRVKEVRASTRLKSHPVCLTVAGD
HHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
VSIEMEKILNAMPNGGGMKAEKVLEVNADHAIFQTLQRVYKEDEAKAKQYTDLLYQQALL
CCEEHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLPIEDPVAYSNAVCALMAE
HCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]