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The map label for this gene is yacO [H]

Identifier: 229917377

GI number: 229917377

Start: 1594695

End: 1595447

Strand: Reverse

Name: yacO [H]

Synonym: EAT1b_1652

Alternate gene names: 229917377

Gene position: 1595447-1594695 (Counterclockwise)

Preceding gene: 229917378

Following gene: 229917376

Centisome position: 53.18

GC content: 51.93

Gene sequence:

>753_bases
GTGATGGAGGAAGGGATTGACTTCCTTTACGGTCGTAACCCGGTACTCGAGGCACTGCGAAGTGGTCGGGATATGAATAA
AGTATTCATTATGGAAGGTCAGCAAAAGGGCCCACTCGCTCAAATTATCGCGATGGCGAACGAAGCATCGGTCCAAGTGT
CATTCGTCCCAAAAACGAAACTTGAGAAGATGGCTGGCAGTGAACATCACCAAGGAGTCGTTGCGGCAGTTGCGGCTTAT
GAATACAAAACAGTTGAGGACATGTTCGCTCTCGCAGCTTCGAAAGAGGAGACACCGCTCTTCATTTTACTAGATGAGCT
CGAAGACCCGCACAATCTCGGTTCGATTTTACGGACCGCCGATGCCGTTGGCGCACACGGGATCATCATTCCGAAACGCC
GCTCGGTCGGTTTGACTCAAACGGTCGCCAAAGCTTCAACCGGTGCGATTGAGCATATTCCGGTGGCGCGCGTGACGAAC
TTGACGCGGACACTTGAAGAGTTGAAGGAAAAAGGATTGTGGGTCGTCGGGACCGATGCGAAAGAAAGTCAGGACTATCG
TCGATTGGATGGAAATATGCCACTCGTTGTGGTCATTGGAAGTGAAGGCAAAGGGATGAGCCGACTCGTGCGCGAATCGT
GCGACTTCCTTGTTCATTTACCGATGGTCGGTCATGTCACGTCACTCAATGCATCTGTTGCAGCGGCGCTCCTCCTGTAT
GAGGTGCATCGCTCACGTCATCCATTGGCATGA

Upstream 100 bases:

>100_bases
TCGGGGAGCGGAGAAACGAACGTTTGACCGCCCTCGTGGGGAACGACCAGATCGCGCGCGTCGCCAAAAGGCAGAACGCC
CTGACTATAAGGAAGTCGAT

Downstream 100 bases:

>100_bases
GTATCCTGAAGCGTGAGCTCCTTCTTGTCGACGGATATAATATCATCGGCGCGTGGCCTCACTTGAGAAGTCTCCGCGAC
GTAGATTTTGAACAAGCACG

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MMEEGIDFLYGRNPVLEALRSGRDMNKVFIMEGQQKGPLAQIIAMANEASVQVSFVPKTKLEKMAGSEHHQGVVAAVAAY
EYKTVEDMFALAASKEETPLFILLDELEDPHNLGSILRTADAVGAHGIIIPKRRSVGLTQTVAKASTGAIEHIPVARVTN
LTRTLEELKEKGLWVVGTDAKESQDYRRLDGNMPLVVVIGSEGKGMSRLVRESCDFLVHLPMVGHVTSLNASVAAALLLY
EVHRSRHPLA

Sequences:

>Translated_250_residues
MMEEGIDFLYGRNPVLEALRSGRDMNKVFIMEGQQKGPLAQIIAMANEASVQVSFVPKTKLEKMAGSEHHQGVVAAVAAY
EYKTVEDMFALAASKEETPLFILLDELEDPHNLGSILRTADAVGAHGIIIPKRRSVGLTQTVAKASTGAIEHIPVARVTN
LTRTLEELKEKGLWVVGTDAKESQDYRRLDGNMPLVVVIGSEGKGMSRLVRESCDFLVHLPMVGHVTSLNASVAAALLLY
EVHRSRHPLA
>Mature_250_residues
MMEEGIDFLYGRNPVLEALRSGRDMNKVFIMEGQQKGPLAQIIAMANEASVQVSFVPKTKLEKMAGSEHHQGVVAAVAAY
EYKTVEDMFALAASKEETPLFILLDELEDPHNLGSILRTADAVGAHGIIIPKRRSVGLTQTVAKASTGAIEHIPVARVTN
LTRTLEELKEKGLWVVGTDAKESQDYRRLDGNMPLVVVIGSEGKGMSRLVRESCDFLVHLPMVGHVTSLNASVAAALLLY
EVHRSRHPLA

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=259, Percent_Identity=29.3436293436293, Blast_Score=107, Evalue=8e-24,
Organism=Escherichia coli, GI1790623, Length=241, Percent_Identity=37.7593360995851, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1790083, Length=169, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788935, Length=191, Percent_Identity=26.7015706806283, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555908, Length=253, Percent_Identity=28.8537549407115, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324775, Length=286, Percent_Identity=25.5244755244755, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27278; Mature: 27278

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEEGIDFLYGRNPVLEALRSGRDMNKVFIMEGQQKGPLAQIIAMANEASVQVSFVPKTK
CCCCCCHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHH
LEKMAGSEHHQGVVAAVAAYEYKTVEDMFALAASKEETPLFILLDELEDPHNLGSILRTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHH
DAVGAHGIIIPKRRSVGLTQTVAKASTGAIEHIPVARVTNLTRTLEELKEKGLWVVGTDA
HHCCCCCEEEECCCCCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCEEEECCC
KESQDYRRLDGNMPLVVVIGSEGKGMSRLVRESCDFLVHLPMVGHVTSLNASVAAALLLY
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCHHHCHHHHHHHHHHH
EVHRSRHPLA
HHHHHCCCCC
>Mature Secondary Structure
MMEEGIDFLYGRNPVLEALRSGRDMNKVFIMEGQQKGPLAQIIAMANEASVQVSFVPKTK
CCCCCCHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHH
LEKMAGSEHHQGVVAAVAAYEYKTVEDMFALAASKEETPLFILLDELEDPHNLGSILRTA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHH
DAVGAHGIIIPKRRSVGLTQTVAKASTGAIEHIPVARVTNLTRTLEELKEKGLWVVGTDA
HHCCCCCEEEECCCCCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCEEEECCC
KESQDYRRLDGNMPLVVVIGSEGKGMSRLVRESCDFLVHLPMVGHVTSLNASVAAALLLY
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCHHHCHHHHHHHHHHH
EVHRSRHPLA
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]