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The map label for this gene is yfeW [C]

Identifier: 229917206

GI number: 229917206

Start: 1453027

End: 1454043

Strand: Direct

Name: yfeW [C]

Synonym: EAT1b_1481

Alternate gene names: 229917206

Gene position: 1453027-1454043 (Clockwise)

Preceding gene: 229917204

Following gene: 229917207

Centisome position: 48.44

GC content: 47.2

Gene sequence:

>1017_bases
ATGACACATTTCACACATCCACCGATCGACGAGACATGTTCGGGTGTCTATTTGGTCACGAATCGAAACGGATCGATCCA
CCAGTCATACGGCTATGCGAATCGCTCAGAACAGATTCAACATGACGTGACGACACGGTTCGGAATCGCGTCCGGTTGCA
AGCTGTTTACAGCAATCGCGATTTCTCAGTTAGTCGAGCAAGGGAAACTATCCTTCTCCACCTCGCTTGACTCGTTTCAA
ACATTCGACTTACCTCATCTGTCACCAAACGTCACCGTGCATCAACTGTTGACGCACACGTCGGGAATCCCTGACTATTT
TGATGAATCCGTCTCTGATGACTTTGAAGCGCTATGGCATGATATTCCGATGTATCGACTTCAACAGTTACGTGATTTTT
TACCGCTGTTTCAACAAAAATCCATGAAAGACGAGCCGGGGTCTCGATTCTCCTACAACAATGCGGGGTATATTCTGTTA
GGGTTGATTGTGGAAGAAGTGACCGGTCAATCTTTCACCGATTACGTCGAACAATCGATTTTTCAGCCTGCCGGTATGAC
CGATTCCGGATACTTTTCACTCGATGCCTTGCCTTCTAAAACAGCACTCGGTTATATCGACCACCCGGACGGCACATGGC
GTACAAACCAATATGCGATTCCAATCAAGGGAGGAGCAGATGGCGGAGCTTATGTGACCGTTCAAGATATGACCCGTTTT
TGGAAAGCATTGTTTTCACATCAGCTACTGGACGCCGCATCCACCTCCCTCCTTCTCACACCACATGTGATGATCAATGA
CCGCGGCGGAAGTTATGGATACGGACTTTGGATTCAACATCACGCGTCGGGAGACGTCTATAAATATCATGTGATGGGAT
ATGACCCCGGTGTCAGTTTCCATTCGGGTTACTATCCAGAAATCGATACCATCTCGGTTATTTGTTCAAATCAATCAGAT
GGGGCGTTCGACATGATGAAACAGATTGAAATACAGATTGGAGAGCGGCTCGAATGA

Upstream 100 bases:

>100_bases
TTTGGTAAATGTTTTTTTGAAAATTGAGTAAATTTCAGAGAGATTGTGACGGACATGATATAGTCGACTTATTGAATCAC
TCAATACACGGAGGTTTCTC

Downstream 100 bases:

>100_bases
ACATTCGGAATTATATGGAATCAGACTTTGACTCGATTCAACAACTCAATCACGACGAAGGTTGGAACCAATTGGTAGAA
CGTGACGCATTGACCCGTGA

Product: beta-lactamase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTHFTHPPIDETCSGVYLVTNRNGSIHQSYGYANRSEQIQHDVTTRFGIASGCKLFTAIAISQLVEQGKLSFSTSLDSFQ
TFDLPHLSPNVTVHQLLTHTSGIPDYFDESVSDDFEALWHDIPMYRLQQLRDFLPLFQQKSMKDEPGSRFSYNNAGYILL
GLIVEEVTGQSFTDYVEQSIFQPAGMTDSGYFSLDALPSKTALGYIDHPDGTWRTNQYAIPIKGGADGGAYVTVQDMTRF
WKALFSHQLLDAASTSLLLTPHVMINDRGGSYGYGLWIQHHASGDVYKYHVMGYDPGVSFHSGYYPEIDTISVICSNQSD
GAFDMMKQIEIQIGERLE

Sequences:

>Translated_338_residues
MTHFTHPPIDETCSGVYLVTNRNGSIHQSYGYANRSEQIQHDVTTRFGIASGCKLFTAIAISQLVEQGKLSFSTSLDSFQ
TFDLPHLSPNVTVHQLLTHTSGIPDYFDESVSDDFEALWHDIPMYRLQQLRDFLPLFQQKSMKDEPGSRFSYNNAGYILL
GLIVEEVTGQSFTDYVEQSIFQPAGMTDSGYFSLDALPSKTALGYIDHPDGTWRTNQYAIPIKGGADGGAYVTVQDMTRF
WKALFSHQLLDAASTSLLLTPHVMINDRGGSYGYGLWIQHHASGDVYKYHVMGYDPGVSFHSGYYPEIDTISVICSNQSD
GAFDMMKQIEIQIGERLE
>Mature_337_residues
THFTHPPIDETCSGVYLVTNRNGSIHQSYGYANRSEQIQHDVTTRFGIASGCKLFTAIAISQLVEQGKLSFSTSLDSFQT
FDLPHLSPNVTVHQLLTHTSGIPDYFDESVSDDFEALWHDIPMYRLQQLRDFLPLFQQKSMKDEPGSRFSYNNAGYILLG
LIVEEVTGQSFTDYVEQSIFQPAGMTDSGYFSLDALPSKTALGYIDHPDGTWRTNQYAIPIKGGADGGAYVTVQDMTRFW
KALFSHQLLDAASTSLLLTPHVMINDRGGSYGYGLWIQHHASGDVYKYHVMGYDPGVSFHSGYYPEIDTISVICSNQSDG
AFDMMKQIEIQIGERLE

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=178, Percent_Identity=28.6516853932584, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=168, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 37824; Mature: 37692

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFTHPPIDETCSGVYLVTNRNGSIHQSYGYANRSEQIQHDVTTRFGIASGCKLFTAIA
CCCCCCCCCCHHCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
ISQLVEQGKLSFSTSLDSFQTFDLPHLSPNVTVHQLLTHTSGIPDYFDESVSDDFEALWH
HHHHHHHCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DIPMYRLQQLRDFLPLFQQKSMKDEPGSRFSYNNAGYILLGLIVEEVTGQSFTDYVEQSI
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHH
FQPAGMTDSGYFSLDALPSKTALGYIDHPDGTWRTNQYAIPIKGGADGGAYVTVQDMTRF
CCCCCCCCCCCEEECCCCCCCEEEEEECCCCCEECCEEEEEECCCCCCCCEEEHHHHHHH
WKALFSHQLLDAASTSLLLTPHVMINDRGGSYGYGLWIQHHASGDVYKYHVMGYDPGVSF
HHHHHHHHHHHHCCCEEEEECEEEEECCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCC
HSGYYPEIDTISVICSNQSDGAFDMMKQIEIQIGERLE
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THFTHPPIDETCSGVYLVTNRNGSIHQSYGYANRSEQIQHDVTTRFGIASGCKLFTAIA
CCCCCCCCCHHCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
ISQLVEQGKLSFSTSLDSFQTFDLPHLSPNVTVHQLLTHTSGIPDYFDESVSDDFEALWH
HHHHHHHCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DIPMYRLQQLRDFLPLFQQKSMKDEPGSRFSYNNAGYILLGLIVEEVTGQSFTDYVEQSI
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHH
FQPAGMTDSGYFSLDALPSKTALGYIDHPDGTWRTNQYAIPIKGGADGGAYVTVQDMTRF
CCCCCCCCCCCEEECCCCCCCEEEEEECCCCCEECCEEEEEECCCCCCCCEEEHHHHHHH
WKALFSHQLLDAASTSLLLTPHVMINDRGGSYGYGLWIQHHASGDVYKYHVMGYDPGVSF
HHHHHHHHHHHHCCCEEEEECEEEEECCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCC
HSGYYPEIDTISVICSNQSDGAFDMMKQIEIQIGERLE
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]