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The map label for this gene is yhcK [H]

Identifier: 229917194

GI number: 229917194

Start: 1434121

End: 1435197

Strand: Direct

Name: yhcK [H]

Synonym: EAT1b_1468

Alternate gene names: 229917194

Gene position: 1434121-1435197 (Clockwise)

Preceding gene: 229917187

Following gene: 229917203

Centisome position: 47.81

GC content: 48.28

Gene sequence:

>1077_bases
ATGCTCACAATCATAAATGCGTTCTTTATCAACCTGTGTATCTTGTTCACGCTCTTCACGATTTCCTTTTTACCGTTTCG
CAATCGACCTCGTTTAACCCCACAGTCTCCTTTGAAAGGAAGGGTTTTACTCGGGGTGCAGACCGGATTGATTGCCATCC
TCCTTTTAGCGAATGCCTTACCTCTTGAAGGTGTACTCATTGATTTACGCGCCATCCCAATCATGCTGGCTGTCTTATTT
GGTGGTTGGGTCAGTGGGACGGTTGCAGGTATCATCTATTTGATTGGTCGCGCGTTTGTCGTTTGGTACACAAACGGCGC
TATGATTGGTCTCTATTTAGCGTTTGCGACAATGTTCGTTCTCGTGGGATCAATCAGCATCCTTCGAAAACGCATGGATA
ATACCCGCCCAACTTTACTTATATTCACTACGATCAGCATCGCCATTTTTGGAGCAGCGATTTATGCCGCGCTTCCACTA
AATTTGTTCTATCCCGTCTTAATCGTCTACACGTTAATGTCTTACGGCGGAGCTTGCGCCGCCTATCGATTGTTGCTCGA
ATTGCGCCGCCATTTCGAGAACGTCCAGCATCAACAGCAACTGGCGCGTACGGATGCGCTCACCGGGATTGCCAATCGGC
GTCTCTTGAACGAAGCGATGGCCAACTTGACGGTCGAGGCAGAAGAATACGCATTGATTTTGGTCGATATCGATCATTTC
AAACGGGTAAATGACACATACGGTCACGACGTCGGAGATGATGTCTTGCGCGAGCTCGGCATGCTCCTCGTCAACGAGAG
CGACGAGCGCCATTTGGTCGGCCGCTTCGGTGGCGAAGAATTTTTAATCGTCATGCCACATGCGACACGTAACGAAGTAT
CACGGCTTGCTGAATCTATTCGAGAAAAGGTTTCAACGTTCCCATTCGAGACGAGTGCCGGTACGCTCCACATCACTGTT
TCGCTTGGAGCTTGCCATTCGAATGATATTGAAATCGACAGTGTGTTAAAACATGCAGATGAAGCGTTATATCACGCAAA
AGAGTCCGGTCGAAATCGTTTCATCCTCGCCTCTTAA

Upstream 100 bases:

>100_bases
AAGAGAGCTTCTTTCCGCAAGCAGGTTATTCCTGTTTGTTTCCAACTATATGCTATATACTGTAACTAAATATTTCCATA
CGGGATAAGGGGGAGCTCCG

Downstream 100 bases:

>100_bases
TGTGTCAAACTCTTCACACTTGAGCGCGTTTTCTCGCTTTACTTTCTCGAAATGAATCGTTAAACTAGGCTAGACTTTGA
TTCAGATCGATACATCATGA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLTIINAFFINLCILFTLFTISFLPFRNRPRLTPQSPLKGRVLLGVQTGLIAILLLANALPLEGVLIDLRAIPIMLAVLF
GGWVSGTVAGIIYLIGRAFVVWYTNGAMIGLYLAFATMFVLVGSISILRKRMDNTRPTLLIFTTISIAIFGAAIYAALPL
NLFYPVLIVYTLMSYGGACAAYRLLLELRRHFENVQHQQQLARTDALTGIANRRLLNEAMANLTVEAEEYALILVDIDHF
KRVNDTYGHDVGDDVLRELGMLLVNESDERHLVGRFGGEEFLIVMPHATRNEVSRLAESIREKVSTFPFETSAGTLHITV
SLGACHSNDIEIDSVLKHADEALYHAKESGRNRFILAS

Sequences:

>Translated_358_residues
MLTIINAFFINLCILFTLFTISFLPFRNRPRLTPQSPLKGRVLLGVQTGLIAILLLANALPLEGVLIDLRAIPIMLAVLF
GGWVSGTVAGIIYLIGRAFVVWYTNGAMIGLYLAFATMFVLVGSISILRKRMDNTRPTLLIFTTISIAIFGAAIYAALPL
NLFYPVLIVYTLMSYGGACAAYRLLLELRRHFENVQHQQQLARTDALTGIANRRLLNEAMANLTVEAEEYALILVDIDHF
KRVNDTYGHDVGDDVLRELGMLLVNESDERHLVGRFGGEEFLIVMPHATRNEVSRLAESIREKVSTFPFETSAGTLHITV
SLGACHSNDIEIDSVLKHADEALYHAKESGRNRFILAS
>Mature_358_residues
MLTIINAFFINLCILFTLFTISFLPFRNRPRLTPQSPLKGRVLLGVQTGLIAILLLANALPLEGVLIDLRAIPIMLAVLF
GGWVSGTVAGIIYLIGRAFVVWYTNGAMIGLYLAFATMFVLVGSISILRKRMDNTRPTLLIFTTISIAIFGAAIYAALPL
NLFYPVLIVYTLMSYGGACAAYRLLLELRRHFENVQHQQQLARTDALTGIANRRLLNEAMANLTVEAEEYALILVDIDHF
KRVNDTYGHDVGDDVLRELGMLLVNESDERHLVGRFGGEEFLIVMPHATRNEVSRLAESIREKVSTFPFETSAGTLHITV
SLGACHSNDIEIDSVLKHADEALYHAKESGRNRFILAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=216, Percent_Identity=36.1111111111111, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787816, Length=189, Percent_Identity=36.5079365079365, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=208, Percent_Identity=31.7307692307692, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=34.8837209302326, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787802, Length=159, Percent_Identity=33.9622641509434, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=35.5828220858896, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787541, Length=160, Percent_Identity=30.625, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788381, Length=158, Percent_Identity=32.2784810126582, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=29.2397660818713, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787056, Length=150, Percent_Identity=35.3333333333333, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081977, Length=151, Percent_Identity=31.1258278145695, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788956, Length=166, Percent_Identity=31.9277108433735, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=301, Percent_Identity=23.5880398671096, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 39765; Mature: 39765

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIINAFFINLCILFTLFTISFLPFRNRPRLTPQSPLKGRVLLGVQTGLIAILLLANAL
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCC
PLEGVLIDLRAIPIMLAVLFGGWVSGTVAGIIYLIGRAFVVWYTNGAMIGLYLAFATMFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
LVGSISILRKRMDNTRPTLLIFTTISIAIFGAAIYAALPLNLFYPVLIVYTLMSYGGACA
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYRLLLELRRHFENVQHQQQLARTDALTGIANRRLLNEAMANLTVEAEEYALILVDIDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEEHHHH
KRVNDTYGHDVGDDVLRELGMLLVNESDERHLVGRFGGEEFLIVMPHATRNEVSRLAESI
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
REKVSTFPFETSAGTLHITVSLGACHSNDIEIDSVLKHADEALYHAKESGRNRFILAS
HHHHHCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MLTIINAFFINLCILFTLFTISFLPFRNRPRLTPQSPLKGRVLLGVQTGLIAILLLANAL
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCC
PLEGVLIDLRAIPIMLAVLFGGWVSGTVAGIIYLIGRAFVVWYTNGAMIGLYLAFATMFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
LVGSISILRKRMDNTRPTLLIFTTISIAIFGAAIYAALPLNLFYPVLIVYTLMSYGGACA
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYRLLLELRRHFENVQHQQQLARTDALTGIANRRLLNEAMANLTVEAEEYALILVDIDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEEHHHH
KRVNDTYGHDVGDDVLRELGMLLVNESDERHLVGRFGGEEFLIVMPHATRNEVSRLAESI
HHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
REKVSTFPFETSAGTLHITVSLGACHSNDIEIDSVLKHADEALYHAKESGRNRFILAS
HHHHHCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]