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The map label for this gene is gph [H]

Identifier: 229917188

GI number: 229917188

Start: 1429820

End: 1430452

Strand: Reverse

Name: gph [H]

Synonym: EAT1b_1462

Alternate gene names: 229917188

Gene position: 1430452-1429820 (Counterclockwise)

Preceding gene: 229917189

Following gene: 229917186

Centisome position: 47.68

GC content: 51.03

Gene sequence:

>633_bases
ATGGCAGTGATTTTATTTGATATCGATGGCACGTTAGTAGATACGACCGGACCGATGACGAAGGCGATTCATGAGGCACT
CGAGGAGCTTCCTCATCTTCCGAAACCGAGTGAAGAGGCGGTCCGCTCAGGATACGGCTTGGCAGGTAACGCGTTTTGGG
AGCATGTCATCCCAAAGGCGACGCTCGAAGAGATTCGTCTCATTCGCAGACTCCGTCATACGACGCTTGAGCAAACGATG
GAAGGGCAAAATGTCTTGTTTGACGGAATTCGTGAGATGTTGGAGACGCTTCATGAGCAAGGTCATACGCTGACGACAGC
GAGTAATTGTGGTGTTCATTACATGAATTTGATTTTAGATACGCAACAAATTCGTCCATATATGACGGCACCCGAATGCT
TAGAGTCTGTTGGAGGCGAGAAGAAGGCAGACATTCTGACAGCACACCGTGTCCGGCACGGAGAGGCGGACTATATTATG
GTCGGCGATCGTAAGTCGGATGTCGAGGCGGCTCGTGCACATGACTTCCCGGTCGTCTTGACAGGGTTCGGATTCGGCAA
TGAAGAAGAGTGGGCACTTGCGGATCACGTGATCCAGTCTCCGCATGATTTAGTCGAGTGGGTCAACCGATAA

Upstream 100 bases:

>100_bases
CGAATCGGTTCAGTCGTTTTTTTGTCATCACGTTTTCTCTTTTGCATTTTCGGGGATTCTGCTACGGTAAGGAGAGAGTG
AAAGAGAGGGGATCAATCCA

Downstream 100 bases:

>100_bases
GAAAAGGCTTGTCGCATATGTCGACAAGCCTTTTGTATACCTACACTTACAACCCGAGTGAGATGTATTTTACTTCTAAA
AATTCCTCGATGCCGTGATG

Product: HAD-superfamily hydrolase, subfamily IA, variant 1

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MAVILFDIDGTLVDTTGPMTKAIHEALEELPHLPKPSEEAVRSGYGLAGNAFWEHVIPKATLEEIRLIRRLRHTTLEQTM
EGQNVLFDGIREMLETLHEQGHTLTTASNCGVHYMNLILDTQQIRPYMTAPECLESVGGEKKADILTAHRVRHGEADYIM
VGDRKSDVEAARAHDFPVVLTGFGFGNEEEWALADHVIQSPHDLVEWVNR

Sequences:

>Translated_210_residues
MAVILFDIDGTLVDTTGPMTKAIHEALEELPHLPKPSEEAVRSGYGLAGNAFWEHVIPKATLEEIRLIRRLRHTTLEQTM
EGQNVLFDGIREMLETLHEQGHTLTTASNCGVHYMNLILDTQQIRPYMTAPECLESVGGEKKADILTAHRVRHGEADYIM
VGDRKSDVEAARAHDFPVVLTGFGFGNEEEWALADHVIQSPHDLVEWVNR
>Mature_209_residues
AVILFDIDGTLVDTTGPMTKAIHEALEELPHLPKPSEEAVRSGYGLAGNAFWEHVIPKATLEEIRLIRRLRHTTLEQTME
GQNVLFDGIREMLETLHEQGHTLTTASNCGVHYMNLILDTQQIRPYMTAPECLESVGGEKKADILTAHRVRHGEADYIMV
GDRKSDVEAARAHDFPVVLTGFGFGNEEEWALADHVIQSPHDLVEWVNR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23558; Mature: 23427

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVILFDIDGTLVDTTGPMTKAIHEALEELPHLPKPSEEAVRSGYGLAGNAFWEHVIPKA
CEEEEEECCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHCCHH
TLEEIRLIRRLRHTTLEQTMEGQNVLFDGIREMLETLHEQGHTLTTASNCGVHYMNLILD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
TQQIRPYMTAPECLESVGGEKKADILTAHRVRHGEADYIMVGDRKSDVEAARAHDFPVVL
HHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCEEE
TGFGFGNEEEWALADHVIQSPHDLVEWVNR
EECCCCCCCCHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
AVILFDIDGTLVDTTGPMTKAIHEALEELPHLPKPSEEAVRSGYGLAGNAFWEHVIPKA
EEEEEECCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHCCHH
TLEEIRLIRRLRHTTLEQTMEGQNVLFDGIREMLETLHEQGHTLTTASNCGVHYMNLILD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
TQQIRPYMTAPECLESVGGEKKADILTAHRVRHGEADYIMVGDRKSDVEAARAHDFPVVL
HHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCEEE
TGFGFGNEEEWALADHVIQSPHDLVEWVNR
EECCCCCCCCHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11114933 [H]