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The map label for this gene is murQ

Identifier: 229917119

GI number: 229917119

Start: 1364540

End: 1365424

Strand: Reverse

Name: murQ

Synonym: EAT1b_1393

Alternate gene names: 229917119

Gene position: 1365424-1364540 (Counterclockwise)

Preceding gene: 229917120

Following gene: 229917118

Centisome position: 45.52

GC content: 50.51

Gene sequence:

>885_bases
ATGCTAGATAAATTGGCTACAGAAAGACGGAATGAACAAACGATGCACCTGGACGAGATGTCGATTGAGGAACGATTGAC
GATTATGAATGCAGAGGATCATAAAGTTCCTCAAGTGATTCAAGAGCAACTTCCGGTCATCACACAAGTCGTGGAGCGAG
TCATCGCATCCTTTCGTAAAGGCGGTCGCTTGATTTATATCGGTGCAGGTACGAGCGGACGTTTAGGAATTCTAGACGCA
GCGGAGTGTGTGCCAACGTTTGGCGTGTCACCTAATCAAGTCATCGGACTGATTGCCGGCGGCGAACGCGCGCTCATTCA
AGCCGTTGAGGGAGCAGAAGACAGTAAGGAATTGGCAGTCACAGATTTGAAAGCGCTTCATTTGACGGCAGAGGATACGG
TCGTGGGGATTGCAGCGAGCGGTCGAACACCATATGTGGTCGGAGGTCTCGATTATGCACGGGAACTCGGTGCCACAACA
GCTTCGATTTCATGTAATCGCGATGCGGTCATCAGTCGACATGCGGATTACCCGATTGAAGTGGAAACGGGACCGGAAGT
ACTGACCGGTTCAACGAGATTGAAGGCGGGAACAGCACAGAAACTTGTCCTCAACATGATTTCGACGACGTCGATGATTG
GAGTAGGGAAAGTGTATCAAAACTTGATGGTTGATGTGCAACCGACGAATGAAAAGCTAGAAGTGCGTGCCAAGCGGATG
ATTGCAGAAGCGACAGGGGTCGACATGGAAATGGCCGCGCGTTATTTTGCTTCATCCAAGGGGCACGTCAAAACGGCGAT
CGTCATGATTTTAGCGGACGTCTCTTATGAGGAGGCTGTCAAACGATTAGAGCGCGCGAACGGATTCGTACGCGAGGCGC
TATAA

Upstream 100 bases:

>100_bases
GAATCCTCTTTGAAATTAAATTTCATAAAAATTAAATTATAAATTGACTTTTAATTTCAATATAGTACGATGAAATCATA
GAGAAGAAAGGATGGTGGCG

Downstream 100 bases:

>100_bases
GGGGGAAATCGAGATGAAGAAAGAAGAGGTTTTAGCACGGGATATCCTCGCACATGTCGGGGGGAAAGAGAACATCCGTC
AACTCGCGCATTGTATGACA

Product: glucokinase regulatory-like protein

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLDKLATERRNEQTMHLDEMSIEERLTIMNAEDHKVPQVIQEQLPVITQVVERVIASFRKGGRLIYIGAGTSGRLGILDA
AECVPTFGVSPNQVIGLIAGGERALIQAVEGAEDSKELAVTDLKALHLTAEDTVVGIAASGRTPYVVGGLDYARELGATT
ASISCNRDAVISRHADYPIEVETGPEVLTGSTRLKAGTAQKLVLNMISTTSMIGVGKVYQNLMVDVQPTNEKLEVRAKRM
IAEATGVDMEMAARYFASSKGHVKTAIVMILADVSYEEAVKRLERANGFVREAL

Sequences:

>Translated_294_residues
MLDKLATERRNEQTMHLDEMSIEERLTIMNAEDHKVPQVIQEQLPVITQVVERVIASFRKGGRLIYIGAGTSGRLGILDA
AECVPTFGVSPNQVIGLIAGGERALIQAVEGAEDSKELAVTDLKALHLTAEDTVVGIAASGRTPYVVGGLDYARELGATT
ASISCNRDAVISRHADYPIEVETGPEVLTGSTRLKAGTAQKLVLNMISTTSMIGVGKVYQNLMVDVQPTNEKLEVRAKRM
IAEATGVDMEMAARYFASSKGHVKTAIVMILADVSYEEAVKRLERANGFVREAL
>Mature_294_residues
MLDKLATERRNEQTMHLDEMSIEERLTIMNAEDHKVPQVIQEQLPVITQVVERVIASFRKGGRLIYIGAGTSGRLGILDA
AECVPTFGVSPNQVIGLIAGGERALIQAVEGAEDSKELAVTDLKALHLTAEDTVVGIAASGRTPYVVGGLDYARELGATT
ASISCNRDAVISRHADYPIEVETGPEVLTGSTRLKAGTAQKLVLNMISTTSMIGVGKVYQNLMVDVQPTNEKLEVRAKRM
IAEATGVDMEMAARYFASSKGHVKTAIVMILADVSYEEAVKRLERANGFVREAL

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=293, Percent_Identity=53.5836177474403, Blast_Score=303, Evalue=7e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_EXISA (C4KZ07)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885765.1
- ProteinModelPortal:   C4KZ07
- GeneID:   7869387
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1393
- OMA:   SMIGVGK
- ProtClustDB:   CLSK2489333
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31753; Mature: 31753

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 82-82 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKLATERRNEQTMHLDEMSIEERLTIMNAEDHKVPQVIQEQLPVITQVVERVIASFRK
CCCCHHHHHCCCCEEEHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGRLIYIGAGTSGRLGILDAAECVPTFGVSPNQVIGLIAGGERALIQAVEGAEDSKELAV
CCEEEEEECCCCCCEECEEHHHHCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHH
TDLKALHLTAEDTVVGIAASGRTPYVVGGLDYARELGATTASISCNRDAVISRHADYPIE
HHHEEEEEECCCEEEEEEECCCCCEEECCHHHHHHHCCCEEEEECCCCHHHHCCCCCCEE
VETGPEVLTGSTRLKAGTAQKLVLNMISTTSMIGVGKVYQNLMVDVQPTNEKLEVRAKRM
ECCCCCEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
IAEATGVDMEMAARYFASSKGHVKTAIVMILADVSYEEAVKRLERANGFVREAL
HHHHCCCCHHHHHHHHHCCCCCHHHEEEHHHHCCCHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MLDKLATERRNEQTMHLDEMSIEERLTIMNAEDHKVPQVIQEQLPVITQVVERVIASFRK
CCCCHHHHHCCCCEEEHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGRLIYIGAGTSGRLGILDAAECVPTFGVSPNQVIGLIAGGERALIQAVEGAEDSKELAV
CCEEEEEECCCCCCEECEEHHHHCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCHHHH
TDLKALHLTAEDTVVGIAASGRTPYVVGGLDYARELGATTASISCNRDAVISRHADYPIE
HHHEEEEEECCCEEEEEEECCCCCEEECCHHHHHHHCCCEEEEECCCCHHHHCCCCCCEE
VETGPEVLTGSTRLKAGTAQKLVLNMISTTSMIGVGKVYQNLMVDVQPTNEKLEVRAKRM
ECCCCCEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
IAEATGVDMEMAARYFASSKGHVKTAIVMILADVSYEEAVKRLERANGFVREAL
HHHHCCCCHHHHHHHHHCCCCCHHHEEEHHHHCCCHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA