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The map label for this gene is glpD [H]

Identifier: 229917078

GI number: 229917078

Start: 1320548

End: 1322206

Strand: Reverse

Name: glpD [H]

Synonym: EAT1b_1352

Alternate gene names: 229917078

Gene position: 1322206-1320548 (Counterclockwise)

Preceding gene: 229917080

Following gene: 229917077

Centisome position: 44.08

GC content: 49.13

Gene sequence:

>1659_bases
ATGGAAATCAGAAATTTCTCAGCGAAAGAACGAGCGAAACGATATGAACAACTGACGAGTGAACGTCATGACGTTCTTGT
TGTCGGTGGCGGGATTACAGGAGCGGGGATTGCGCTCGATGCATCGTCGCGTGGGATGAAGACAGCTGTCCTCGAGATGC
AAGACTTTGCGGCCGGGACATCAAGTCGTTCGACGAAACTTGTTCACGGGGGACTCCGCTATTTGAAACAATTTGAAGTG
GCGCTCGTCGCAGAAGTCGGGAAAGAGCGTGCCATCGTGTATGAGAATGGTCCACACGTCACGACACCGGAACAGATGTT
GTTGCCAATGCATAAAGGAGGCACGTTTGGCCCCTTCTCAACTTCAATCGGACTGATGGTGTATGACTTCCTCGCAGGCG
TCAAACGGGCAGAACGTCGCATGATGCTCAAACCGAATGAAGTCATCAAGAAAGCACCGCTCGTGAAAAAAGATGATTTA
GTCGGAGGCGGTTATTACGTCGAGTACCGGACGGATGATGCGCGATTGACAATCGAAGTGGCGAAAGAAGCGGCAAACCA
TGGTGCGCTTCTCATGAACTATGCGAAAGTGACGGGGTTGATTTACGAAAACGGCAAAGTAGCCGGTGTACACGTTGAAG
ACCAAATCGATGGGGCGACATATGACGTCTATGCGAAGAAAATCATCAATGCGACCGGTCCATGGGTCGATGAGTTACGG
GAAGAAGACAACTCGAAAAAAGGCAAACAACTTCGTTTGACGAAAGGAATTCACCTCGTCATCGATCAATCGAAATTCCC
ACTCAAACAGGCAATTTATTTCGATACACCAGACGGGCGCATGGTCTTTGCCATTCCACGCGGAAACAAAGCGTACGTCG
GAACGACGGACACGTTCTTTGATAAAAACAAAGCCCATCCACGCATGACGACAGAAGACCGCGATTATATTTTGGATGCG
ATTCACTATATGTTCCCGGACGTCCATGTCACGGCAGACGATGTAGAATCGAGCTGGGCGGGTATTCGTCCGTTGATTTA
TGAAGAAGGAAAAGACCCTTCTGAAATTTCACGTAAGGACGAAATTTGGCAGTCAGACAGCGGTTTGATCACGATTGCCG
GCGGTAAATTGACAGGATATCGGAAGATGTCAGAAACAGTCGTCGACCTTGTCGCGAAATTATTAAAAGAAGAAGAAGGC
GTCGTTTACTTGGCGAGCCGGACGAAGCATATGCCGATGTCAGGTGGTCACGTCGGCGGTTCGAAAGGCTTCAAAGACTT
CCTTGAGAAGAAAACGAAAGAACTTCAAAATCACGGTCTAGACGCAAACCACGCGGAAGAACTCGTCCGTCTATACGGTT
CGAATATTGACCGCGTCATCGAGCGGATGGACTCGAACGCGTATGACTTGCCAGAGGTCGTCTATGCGCAGTTGATTTAT
GGCATTGAAGAAGAGTCGGTCGTTCGTGCCATCGACTTCTTGATTCGTCGGACCGGAGCGATGTTCTTTGATATCGATTT
CGTCCGTCAATACAAAGACGGTGTCCTTCGTTGCATGGCCGACGTCTTCAAATGGTCGGATGAGCGTTTGAAAGAAGAGC
GTGAAGAGGTCGAGAAAGAGATTGAAATCGCAGTTGTGCCTGTGACTGTCGAATCGTAA

Upstream 100 bases:

>100_bases
TCGAGACAATAGAGAGACCACAACAGAAGGGGGAAGCCTTGTTTTTGTTGTGGTCTCTTTTTCTATTCATTGAACCATAC
TTACTATAGGAGGGAATAAG

Downstream 100 bases:

>100_bases
TGCACTGTATCGAAGGAAAGGTTCATTCTAAACAGGATGAACCTTTTTTGTGGCATGGTTTCGTCGATTCGGAATAACGG
TATACCTCATAAGTAGTGAT

Product: Glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEIRNFSAKERAKRYEQLTSERHDVLVVGGGITGAGIALDASSRGMKTAVLEMQDFAAGTSSRSTKLVHGGLRYLKQFEV
ALVAEVGKERAIVYENGPHVTTPEQMLLPMHKGGTFGPFSTSIGLMVYDFLAGVKRAERRMMLKPNEVIKKAPLVKKDDL
VGGGYYVEYRTDDARLTIEVAKEAANHGALLMNYAKVTGLIYENGKVAGVHVEDQIDGATYDVYAKKIINATGPWVDELR
EEDNSKKGKQLRLTKGIHLVIDQSKFPLKQAIYFDTPDGRMVFAIPRGNKAYVGTTDTFFDKNKAHPRMTTEDRDYILDA
IHYMFPDVHVTADDVESSWAGIRPLIYEEGKDPSEISRKDEIWQSDSGLITIAGGKLTGYRKMSETVVDLVAKLLKEEEG
VVYLASRTKHMPMSGGHVGGSKGFKDFLEKKTKELQNHGLDANHAEELVRLYGSNIDRVIERMDSNAYDLPEVVYAQLIY
GIEEESVVRAIDFLIRRTGAMFFDIDFVRQYKDGVLRCMADVFKWSDERLKEEREEVEKEIEIAVVPVTVES

Sequences:

>Translated_552_residues
MEIRNFSAKERAKRYEQLTSERHDVLVVGGGITGAGIALDASSRGMKTAVLEMQDFAAGTSSRSTKLVHGGLRYLKQFEV
ALVAEVGKERAIVYENGPHVTTPEQMLLPMHKGGTFGPFSTSIGLMVYDFLAGVKRAERRMMLKPNEVIKKAPLVKKDDL
VGGGYYVEYRTDDARLTIEVAKEAANHGALLMNYAKVTGLIYENGKVAGVHVEDQIDGATYDVYAKKIINATGPWVDELR
EEDNSKKGKQLRLTKGIHLVIDQSKFPLKQAIYFDTPDGRMVFAIPRGNKAYVGTTDTFFDKNKAHPRMTTEDRDYILDA
IHYMFPDVHVTADDVESSWAGIRPLIYEEGKDPSEISRKDEIWQSDSGLITIAGGKLTGYRKMSETVVDLVAKLLKEEEG
VVYLASRTKHMPMSGGHVGGSKGFKDFLEKKTKELQNHGLDANHAEELVRLYGSNIDRVIERMDSNAYDLPEVVYAQLIY
GIEEESVVRAIDFLIRRTGAMFFDIDFVRQYKDGVLRCMADVFKWSDERLKEEREEVEKEIEIAVVPVTVES
>Mature_552_residues
MEIRNFSAKERAKRYEQLTSERHDVLVVGGGITGAGIALDASSRGMKTAVLEMQDFAAGTSSRSTKLVHGGLRYLKQFEV
ALVAEVGKERAIVYENGPHVTTPEQMLLPMHKGGTFGPFSTSIGLMVYDFLAGVKRAERRMMLKPNEVIKKAPLVKKDDL
VGGGYYVEYRTDDARLTIEVAKEAANHGALLMNYAKVTGLIYENGKVAGVHVEDQIDGATYDVYAKKIINATGPWVDELR
EEDNSKKGKQLRLTKGIHLVIDQSKFPLKQAIYFDTPDGRMVFAIPRGNKAYVGTTDTFFDKNKAHPRMTTEDRDYILDA
IHYMFPDVHVTADDVESSWAGIRPLIYEEGKDPSEISRKDEIWQSDSGLITIAGGKLTGYRKMSETVVDLVAKLLKEEEG
VVYLASRTKHMPMSGGHVGGSKGFKDFLEKKTKELQNHGLDANHAEELVRLYGSNIDRVIERMDSNAYDLPEVVYAQLIY
GIEEESVVRAIDFLIRRTGAMFFDIDFVRQYKDGVLRCMADVFKWSDERLKEEREEVEKEIEIAVVPVTVES

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=550, Percent_Identity=34, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI285002231, Length=550, Percent_Identity=34, Blast_Score=280, Evalue=3e-75,
Organism=Escherichia coli, GI2367226, Length=477, Percent_Identity=30.398322851153, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788574, Length=372, Percent_Identity=26.3440860215054, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=543, Percent_Identity=33.7016574585635, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI115534726, Length=530, Percent_Identity=32.8301886792453, Blast_Score=236, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6322036, Length=598, Percent_Identity=30.1003344481605, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI161077125, Length=564, Percent_Identity=33.3333333333333, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24653942, Length=564, Percent_Identity=33.3333333333333, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24653944, Length=564, Percent_Identity=33.3333333333333, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI20130025, Length=564, Percent_Identity=33.3333333333333, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586295, Length=567, Percent_Identity=28.3950617283951, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI19921278, Length=554, Percent_Identity=26.8953068592058, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45550977, Length=405, Percent_Identity=25.4320987654321, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61929; Mature: 61929

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRNFSAKERAKRYEQLTSERHDVLVVGGGITGAGIALDASSRGMKTAVLEMQDFAAGT
CCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCC
SSRSTKLVHGGLRYLKQFEVALVAEVGKERAIVYENGPHVTTPEQMLLPMHKGGTFGPFS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHEEEECCCCCCCCCH
TSIGLMVYDFLAGVKRAERRMMLKPNEVIKKAPLVKKDDLVGGGYYVEYRTDDARLTIEV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEE
AKEAANHGALLMNYAKVTGLIYENGKVAGVHVEDQIDGATYDVYAKKIINATGPWVDELR
HHHHCCCCCEEEEHHHHEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHH
EEDNSKKGKQLRLTKGIHLVIDQSKFPLKQAIYFDTPDGRMVFAIPRGNKAYVGTTDTFF
HHCCCCCCCEEEEECCEEEEEECCCCCHHHEEEEECCCCEEEEEEECCCEEEECCCHHHC
DKNKAHPRMTTEDRDYILDAIHYMFPDVHVTADDVESSWAGIRPLIYEEGKDPSEISRKD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCEECCCCCHHHHHHHH
EIWQSDSGLITIAGGKLTGYRKMSETVVDLVAKLLKEEEGVVYLASRTKHMPMSGGHVGG
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
SKGFKDFLEKKTKELQNHGLDANHAEELVRLYGSNIDRVIERMDSNAYDLPEVVYAQLIY
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHH
GIEEESVVRAIDFLIRRTGAMFFDIDFVRQYKDGVLRCMADVFKWSDERLKEEREEVEKE
CCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
IEIAVVPVTVES
EEEEEEEEEECC
>Mature Secondary Structure
MEIRNFSAKERAKRYEQLTSERHDVLVVGGGITGAGIALDASSRGMKTAVLEMQDFAAGT
CCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCC
SSRSTKLVHGGLRYLKQFEVALVAEVGKERAIVYENGPHVTTPEQMLLPMHKGGTFGPFS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHEEEECCCCCCCCCH
TSIGLMVYDFLAGVKRAERRMMLKPNEVIKKAPLVKKDDLVGGGYYVEYRTDDARLTIEV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEE
AKEAANHGALLMNYAKVTGLIYENGKVAGVHVEDQIDGATYDVYAKKIINATGPWVDELR
HHHHCCCCCEEEEHHHHEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHH
EEDNSKKGKQLRLTKGIHLVIDQSKFPLKQAIYFDTPDGRMVFAIPRGNKAYVGTTDTFF
HHCCCCCCCEEEEECCEEEEEECCCCCHHHEEEEECCCCEEEEEEECCCEEEECCCHHHC
DKNKAHPRMTTEDRDYILDAIHYMFPDVHVTADDVESSWAGIRPLIYEEGKDPSEISRKD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCEECCCCCHHHHHHHH
EIWQSDSGLITIAGGKLTGYRKMSETVVDLVAKLLKEEEGVVYLASRTKHMPMSGGHVGG
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
SKGFKDFLEKKTKELQNHGLDANHAEELVRLYGSNIDRVIERMDSNAYDLPEVVYAQLIY
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHH
GIEEESVVRAIDFLIRRTGAMFFDIDFVRQYKDGVLRCMADVFKWSDERLKEEREEVEKE
CCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
IEIAVVPVTVES
EEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]