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The map label for this gene is ykoH [H]

Identifier: 229917047

GI number: 229917047

Start: 1294884

End: 1296119

Strand: Reverse

Name: ykoH [H]

Synonym: EAT1b_1321

Alternate gene names: 229917047

Gene position: 1296119-1294884 (Counterclockwise)

Preceding gene: 229917048

Following gene: 229917046

Centisome position: 43.21

GC content: 49.43

Gene sequence:

>1236_bases
ATGCTGCGAACAAAAATTGCATGGGCGATGACGGGGTTCATGTTATTGCTTCTTCTCGTCTCCTTTGGCGTGACCTGGTT
CGTCGCCAGGCAGGAAATTGTCGATTCGCGTTTTGACGTGTTACTGCAGGCGTTAAATCTATTAGAAGAAGATGTCCGGA
ATAGCGATGCGGTATTGTCGCTTCATGAGGACAGTGTCGTGTTAGAACGTCAAGAAAACGGCGAATGGGGAATAATCGGG
GGAGAAGTGCCGGACGGAACGACGTTTCCCATCAATTACGGGGAACCGGCCCTCATCGATGATTGGTTTGTGGTCGCGAC
GACGGATGGACTAGCGTTCGGCTTTCAGGATCGAGATGTGAGCAATACGATTCAAGCGCTCGCAACCATTTTTCTCGTCA
TGTTCTTTCTTGCCGTTCTCTTGACGTTCCTCGGGACGTGGTGGATATTACGTCAAGGTTTGTCACCGTTACGCCGATTG
ACAGAGACGATGGAGCGGATCACGGAGTCCGGTAAGTTAGAGACGATCGAAGTGGCTGACCGAAAGGATGAAGTGACGAC
CCTTTCGAACGGATTTAATCATATGATCGAGCGAGTCGAAGGGACGATGGAGCAACAACGTCGTTTCGTCGCCGATGTTT
CACATGAACTCAAGACACCGTTGACCGTCATCGAGGGCTATGCGAAGTTATTACAACGGTGGGGACAAGAAGATGAGAGT
GTACGTGCCGAAGCGATCGACCATATTTTAACGGAGTCGCGTCAAATGCGACATGATTTGATTGAACCGATGCTCGAATT
GAATCGGTTCACTGCACTCGAACAGGTAGAGCGAGAAGAAATCGATTTAGCTGAACTTGGGGAATCCATAGGAGAACGTT
TTGTACGGTCGCACGGCGTCCAGTTACCTATTGAAGCTACAGGAAGCTGGTTCGGTCATCGTGAGTCGTTACAGCGGATT
CTTGTCATCCTATTAGACAATAGTTTGAAGTATGCGGAAGAGACGAGCCTTCATTTAAAGAGTGATCGGATTGAGGTACG
CGATCGAGGACCCGTTCTAACGGATGATGTGAGGAATCGGCTGTTCGACCGATTCTATCGATTGGATGAAGCGCGCGATC
GAAGTGGGAGCGGTCTTGGTCTCGCGATTGCGAAAGAAGTGGCGGACTTGAATGAGTGGACGATCGGAAGTAAATCGAAT
CATCCGGATGGTAGTATATTTTTCCTGACTCGATGA

Upstream 100 bases:

>100_bases
CGTGGACGTGTATGTCCGATACGTCAGGAAAAAACTGACCGGCTCTTGGATTCAAACGGTTCGCGGTGTCGGCTATATGT
TGAAGCGTGGTGAGTGACCG

Downstream 100 bases:

>100_bases
TGAATATTTCGCATTTTCTCATCAACTTCTAATGAAGCCTTAAATATGCTCTCACGGAAGAGGCTTATGATGAAAATAAG
AAGAACACATCATGAGGAGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLRTKIAWAMTGFMLLLLLVSFGVTWFVARQEIVDSRFDVLLQALNLLEEDVRNSDAVLSLHEDSVVLERQENGEWGIIG
GEVPDGTTFPINYGEPALIDDWFVVATTDGLAFGFQDRDVSNTIQALATIFLVMFFLAVLLTFLGTWWILRQGLSPLRRL
TETMERITESGKLETIEVADRKDEVTTLSNGFNHMIERVEGTMEQQRRFVADVSHELKTPLTVIEGYAKLLQRWGQEDES
VRAEAIDHILTESRQMRHDLIEPMLELNRFTALEQVEREEIDLAELGESIGERFVRSHGVQLPIEATGSWFGHRESLQRI
LVILLDNSLKYAEETSLHLKSDRIEVRDRGPVLTDDVRNRLFDRFYRLDEARDRSGSGLGLAIAKEVADLNEWTIGSKSN
HPDGSIFFLTR

Sequences:

>Translated_411_residues
MLRTKIAWAMTGFMLLLLLVSFGVTWFVARQEIVDSRFDVLLQALNLLEEDVRNSDAVLSLHEDSVVLERQENGEWGIIG
GEVPDGTTFPINYGEPALIDDWFVVATTDGLAFGFQDRDVSNTIQALATIFLVMFFLAVLLTFLGTWWILRQGLSPLRRL
TETMERITESGKLETIEVADRKDEVTTLSNGFNHMIERVEGTMEQQRRFVADVSHELKTPLTVIEGYAKLLQRWGQEDES
VRAEAIDHILTESRQMRHDLIEPMLELNRFTALEQVEREEIDLAELGESIGERFVRSHGVQLPIEATGSWFGHRESLQRI
LVILLDNSLKYAEETSLHLKSDRIEVRDRGPVLTDDVRNRLFDRFYRLDEARDRSGSGLGLAIAKEVADLNEWTIGSKSN
HPDGSIFFLTR
>Mature_411_residues
MLRTKIAWAMTGFMLLLLLVSFGVTWFVARQEIVDSRFDVLLQALNLLEEDVRNSDAVLSLHEDSVVLERQENGEWGIIG
GEVPDGTTFPINYGEPALIDDWFVVATTDGLAFGFQDRDVSNTIQALATIFLVMFFLAVLLTFLGTWWILRQGLSPLRRL
TETMERITESGKLETIEVADRKDEVTTLSNGFNHMIERVEGTMEQQRRFVADVSHELKTPLTVIEGYAKLLQRWGQEDES
VRAEAIDHILTESRQMRHDLIEPMLELNRFTALEQVEREEIDLAELGESIGERFVRSHGVQLPIEATGSWFGHRESLQRI
LVILLDNSLKYAEETSLHLKSDRIEVRDRGPVLTDDVRNRLFDRFYRLDEARDRSGSGLGLAIAKEVADLNEWTIGSKSN
HPDGSIFFLTR

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=28.8537549407115, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786783, Length=338, Percent_Identity=26.3313609467456, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=271, Percent_Identity=29.1512915129151, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789403, Length=271, Percent_Identity=26.1992619926199, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.8755186721992, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789808, Length=270, Percent_Identity=27.4074074074074, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788279, Length=290, Percent_Identity=23.1034482758621, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=296, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=25.8181818181818, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787374, Length=270, Percent_Identity=24.8148148148148, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46907; Mature: 46907

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTKIAWAMTGFMLLLLLVSFGVTWFVARQEIVDSRFDVLLQALNLLEEDVRNSDAVLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LHEDSVVLERQENGEWGIIGGEVPDGTTFPINYGEPALIDDWFVVATTDGLAFGFQDRDV
ECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEECCEEEEEECCCCEECCCCCCH
SNTIQALATIFLVMFFLAVLLTFLGTWWILRQGLSPLRRLTETMERITESGKLETIEVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
RKDEVTTLSNGFNHMIERVEGTMEQQRRFVADVSHELKTPLTVIEGYAKLLQRWGQEDES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHH
VRAEAIDHILTESRQMRHDLIEPMLELNRFTALEQVEREEIDLAELGESIGERFVRSHGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
QLPIEATGSWFGHRESLQRILVILLDNSLKYAEETSLHLKSDRIEVRDRGPVLTDDVRNR
EEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCCEEECCCCCCCHHHHHHH
LFDRFYRLDEARDRSGSGLGLAIAKEVADLNEWTIGSKSNHPDGSIFFLTR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MLRTKIAWAMTGFMLLLLLVSFGVTWFVARQEIVDSRFDVLLQALNLLEEDVRNSDAVLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LHEDSVVLERQENGEWGIIGGEVPDGTTFPINYGEPALIDDWFVVATTDGLAFGFQDRDV
ECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEECCEEEEEECCCCEECCCCCCH
SNTIQALATIFLVMFFLAVLLTFLGTWWILRQGLSPLRRLTETMERITESGKLETIEVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
RKDEVTTLSNGFNHMIERVEGTMEQQRRFVADVSHELKTPLTVIEGYAKLLQRWGQEDES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHH
VRAEAIDHILTESRQMRHDLIEPMLELNRFTALEQVEREEIDLAELGESIGERFVRSHGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
QLPIEATGSWFGHRESLQRILVILLDNSLKYAEETSLHLKSDRIEVRDRGPVLTDDVRNR
EEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCCEEECCCCCCCHHHHHHH
LFDRFYRLDEARDRSGSGLGLAIAKEVADLNEWTIGSKSNHPDGSIFFLTR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]