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The map label for this gene is gntK [H]

Identifier: 229916949

GI number: 229916949

Start: 1201500

End: 1202999

Strand: Direct

Name: gntK [H]

Synonym: EAT1b_1223

Alternate gene names: 229916949

Gene position: 1201500-1202999 (Clockwise)

Preceding gene: 229916948

Following gene: 229916950

Centisome position: 40.05

GC content: 55.73

Gene sequence:

>1500_bases
GTGTATACGATTGGGGTCGATATCGGGACGACGAGTACGAAAGCTGTCCTGTTCAACGGTCATCAACAACTGGCGGTACA
TAACGTGTTGTATCCGCTTCTCACGCCCGATACGGAGACGGCCGAGCAAGACCCGGTCGTCATCTACGGGGCCGTGCTTG
AAGCCGTCTCGGCGGTCCGTGCCAAAGCGGACGGTCCGATTCGCTTCGCATCGTTCAGCTCGGCGATGCATAGTTTGATT
GCGCTCGATGCGGCAGGACGTCCGCTCACGAACAGCATCACGTGGGCCGACAGTCGGGCGAATCCGTATACGCAAGAAAT
CAAACGCAACTTTGATGCGAGCGCCCTTCATATGCGTACCGGCACCCCGGTTCATCCGATGGCACCGTTGTCGAAGCTGC
GCTGGTTGAAAGCGGAGCACCCTGAAGTCTTTACCCGGACGGACAAGTTCGTCTCTATCAAAGAATATGTCTTCTATCGG
TTGACGGGACGCTTCGTCGTCGACCATTCCATCGCTTCGGCGACAGGACTGTTCAATCTGAAACAACGAGATTGGGACAC
GGAAGCACTTGAAGTCGCCGGTGTGACTTCAGATCGCTTGTCTGAACTCGTCCCGACAACCGAAACCTTGCAGGTGACGC
CTGACGTGACCGAGACGCTCGGCTGGGACTTCCCGCTCGTCATCGGGGCGAGCGACGGCGTGCTCTCGAACCTCGGGGTC
GGTGCCTTCGAACAAGGTGTCGTCGCCGTGACGATTGGGACGAGCGGCGCTATCCGGACAGTCGTCTCGGAACCGGTCGA
AGATCCAAAAGGTCGTATCTTTTGTTACGCGCTGACGGACAAGCATTGGGTAATCGGTGGACCAGTCAATAACGGCGGCA
TCATTCTCCGCTGGCTCCGTGACGAGTTCGCAGCAAGTGAGGTCGAGACGGCGAAACGACTCGGGATCGACGCGTACGAT
GTGTTGACGCGAATCGCCGAGACGGTCAAACCAGGTGCGGACGGACTCTTGTTCCATCCGTATTTGATGGGTGAACGGGC
TCCACTTTGGGATTCGAACGCTCGCGGTTCATTTTTCGGGCTCAGCATTCACCATAAGCGCGAACATTTCATCCGCGCCG
TATTGGAAGGGGTCATCTTTAACCTTTATACGGTCATGCTCGCACTCGATGAATTGACGGGCGCCCCGAACCGCATCCAT
GCGACCGGTGGTTTTGCCCAGTCGAGCCTTTGGCGTCAGATGATGGCAGACATCTTTGATACACCGGTCGTCGTGCCGGA
GAGTCATGAGAGTTCATGTCTCGGGGCAGTCATGCTCGGGGAATACGCTTTCGGGGATATCGAGGAGTTCCAAGAAGTTC
CACAAGTGACTCATGAGCATACACCGAACATGGAAGCGACGAATGTGTATCGCGAACTTTTGCCGATTTACATTCGCTTA
TCGCGCCATTTGTCTGAGGAATATGAAGCCATTTCAACGTTTCAGCGGAAGCATGTATAA

Upstream 100 bases:

>100_bases
CTCAAGTCATGGACGATTATGGAAACGATTATCGGACTCACCGGCTTCGCCGTTGTGTTCTTGATTAGCCTATTCATCAT
CTAAGTTAGGAAGTGATTGT

Downstream 100 bases:

>100_bases
TGACAAACCGAGTCCTTGAAGGGCTCGGTTTTTTGAATCGTGACAGGAGATTTCGTAATATATACGGAAAGTAAGTGCGA
GGTTAAACTGTCAATATTCT

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MYTIGVDIGTTSTKAVLFNGHQQLAVHNVLYPLLTPDTETAEQDPVVIYGAVLEAVSAVRAKADGPIRFASFSSAMHSLI
ALDAAGRPLTNSITWADSRANPYTQEIKRNFDASALHMRTGTPVHPMAPLSKLRWLKAEHPEVFTRTDKFVSIKEYVFYR
LTGRFVVDHSIASATGLFNLKQRDWDTEALEVAGVTSDRLSELVPTTETLQVTPDVTETLGWDFPLVIGASDGVLSNLGV
GAFEQGVVAVTIGTSGAIRTVVSEPVEDPKGRIFCYALTDKHWVIGGPVNNGGIILRWLRDEFAASEVETAKRLGIDAYD
VLTRIAETVKPGADGLLFHPYLMGERAPLWDSNARGSFFGLSIHHKREHFIRAVLEGVIFNLYTVMLALDELTGAPNRIH
ATGGFAQSSLWRQMMADIFDTPVVVPESHESSCLGAVMLGEYAFGDIEEFQEVPQVTHEHTPNMEATNVYRELLPIYIRL
SRHLSEEYEAISTFQRKHV

Sequences:

>Translated_499_residues
MYTIGVDIGTTSTKAVLFNGHQQLAVHNVLYPLLTPDTETAEQDPVVIYGAVLEAVSAVRAKADGPIRFASFSSAMHSLI
ALDAAGRPLTNSITWADSRANPYTQEIKRNFDASALHMRTGTPVHPMAPLSKLRWLKAEHPEVFTRTDKFVSIKEYVFYR
LTGRFVVDHSIASATGLFNLKQRDWDTEALEVAGVTSDRLSELVPTTETLQVTPDVTETLGWDFPLVIGASDGVLSNLGV
GAFEQGVVAVTIGTSGAIRTVVSEPVEDPKGRIFCYALTDKHWVIGGPVNNGGIILRWLRDEFAASEVETAKRLGIDAYD
VLTRIAETVKPGADGLLFHPYLMGERAPLWDSNARGSFFGLSIHHKREHFIRAVLEGVIFNLYTVMLALDELTGAPNRIH
ATGGFAQSSLWRQMMADIFDTPVVVPESHESSCLGAVMLGEYAFGDIEEFQEVPQVTHEHTPNMEATNVYRELLPIYIRL
SRHLSEEYEAISTFQRKHV
>Mature_499_residues
MYTIGVDIGTTSTKAVLFNGHQQLAVHNVLYPLLTPDTETAEQDPVVIYGAVLEAVSAVRAKADGPIRFASFSSAMHSLI
ALDAAGRPLTNSITWADSRANPYTQEIKRNFDASALHMRTGTPVHPMAPLSKLRWLKAEHPEVFTRTDKFVSIKEYVFYR
LTGRFVVDHSIASATGLFNLKQRDWDTEALEVAGVTSDRLSELVPTTETLQVTPDVTETLGWDFPLVIGASDGVLSNLGV
GAFEQGVVAVTIGTSGAIRTVVSEPVEDPKGRIFCYALTDKHWVIGGPVNNGGIILRWLRDEFAASEVETAKRLGIDAYD
VLTRIAETVKPGADGLLFHPYLMGERAPLWDSNARGSFFGLSIHHKREHFIRAVLEGVIFNLYTVMLALDELTGAPNRIH
ATGGFAQSSLWRQMMADIFDTPVVVPESHESSCLGAVMLGEYAFGDIEEFQEVPQVTHEHTPNMEATNVYRELLPIYIRL
SRHLSEEYEAISTFQRKHV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=457, Percent_Identity=25.164113785558, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI41393575, Length=456, Percent_Identity=25.219298245614, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI4504007, Length=454, Percent_Identity=25.1101321585903, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI189409120, Length=454, Percent_Identity=25.1101321585903, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI88196792, Length=493, Percent_Identity=25.5578093306288, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI164663828, Length=545, Percent_Identity=25.3211009174312, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI18860918, Length=414, Percent_Identity=22.2222222222222, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=28.3400809716599, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790361, Length=492, Percent_Identity=27.2357723577236, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=28.2306163021869, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790005, Length=501, Percent_Identity=24.3512974051896, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789168, Length=387, Percent_Identity=24.5478036175711, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1789138, Length=464, Percent_Identity=23.2758620689655, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535599, Length=452, Percent_Identity=26.7699115044248, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71986140, Length=516, Percent_Identity=20.7364341085271, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321755, Length=431, Percent_Identity=25.754060324826, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655555, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24655560, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24655570, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24655574, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24655565, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17864214, Length=469, Percent_Identity=25.5863539445629, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24654573, Length=381, Percent_Identity=26.7716535433071, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24656367, Length=507, Percent_Identity=20.5128205128205, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357867, Length=522, Percent_Identity=20.3065134099617, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 55094; Mature: 55094

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIGVDIGTTSTKAVLFNGHQQLAVHNVLYPLLTPDTETAEQDPVVIYGAVLEAVSAVR
CEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHH
AKADGPIRFASFSSAMHSLIALDAAGRPLTNSITWADSRANPYTQEIKRNFDASALHMRT
HCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCEEEECC
GTPVHPMAPLSKLRWLKAEHPEVFTRTDKFVSIKEYVFYRLTGRFVVDHSIASATGLFNL
CCCCCCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHEEEHEECCEEEECCHHHHHCCEEC
KQRDWDTEALEVAGVTSDRLSELVPTTETLQVTPDVTETLGWDFPLVIGASDGVLSNLGV
CCCCCCCHHHEEECCCHHHHHHHCCCCCEEEECCCHHHHCCCCCEEEEECCCCHHHHCCC
GAFEQGVVAVTIGTSGAIRTVVSEPVEDPKGRIFCYALTDKHWVIGGPVNNGGIILRWLR
CCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEEEHH
DEFAASEVETAKRLGIDAYDVLTRIAETVKPGADGLLFHPYLMGERAPLWDSNARGSFFG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECHHHCCCCCCCCCCCCCCCEEE
LSIHHKREHFIRAVLEGVIFNLYTVMLALDELTGAPNRIHATGGFAQSSLWRQMMADIFD
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHC
TPVVVPESHESSCLGAVMLGEYAFGDIEEFQEVPQVTHEHTPNMEATNVYRELLPIYIRL
CCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SRHLSEEYEAISTFQRKHV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYTIGVDIGTTSTKAVLFNGHQQLAVHNVLYPLLTPDTETAEQDPVVIYGAVLEAVSAVR
CEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHH
AKADGPIRFASFSSAMHSLIALDAAGRPLTNSITWADSRANPYTQEIKRNFDASALHMRT
HCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCEEEECC
GTPVHPMAPLSKLRWLKAEHPEVFTRTDKFVSIKEYVFYRLTGRFVVDHSIASATGLFNL
CCCCCCCCHHHHHHHHCCCCCCCEECCCCHHHHHHHEEEHEECCEEEECCHHHHHCCEEC
KQRDWDTEALEVAGVTSDRLSELVPTTETLQVTPDVTETLGWDFPLVIGASDGVLSNLGV
CCCCCCCHHHEEECCCHHHHHHHCCCCCEEEECCCHHHHCCCCCEEEEECCCCHHHHCCC
GAFEQGVVAVTIGTSGAIRTVVSEPVEDPKGRIFCYALTDKHWVIGGPVNNGGIILRWLR
CCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEEEHH
DEFAASEVETAKRLGIDAYDVLTRIAETVKPGADGLLFHPYLMGERAPLWDSNARGSFFG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECHHHCCCCCCCCCCCCCCCEEE
LSIHHKREHFIRAVLEGVIFNLYTVMLALDELTGAPNRIHATGGFAQSSLWRQMMADIFD
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHC
TPVVVPESHESSCLGAVMLGEYAFGDIEEFQEVPQVTHEHTPNMEATNVYRELLPIYIRL
CCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SRHLSEEYEAISTFQRKHV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]