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The map label for this gene is ywqF [H]

Identifier: 229916901

GI number: 229916901

Start: 1145774

End: 1147015

Strand: Reverse

Name: ywqF [H]

Synonym: EAT1b_1174

Alternate gene names: 229916901

Gene position: 1147015-1145774 (Counterclockwise)

Preceding gene: 229916903

Following gene: 229916900

Centisome position: 38.24

GC content: 52.9

Gene sequence:

>1242_bases
GTGAAATTTGGAATTATTGGTTTAGGATACGTTGGATTGGCTACACTTTGTGGTTTGGCAAAAGCCGGTCATCACGTCAT
CGGAGTGGAAGCGGACGAAGAGAAGTTGCGTCTTCTCATGAGTGGACATCCGCCATTCCATGAACCAGGCATGGCAGAGG
TGTTGCAAGAGCACGCCGATCAAATCACCCTGACAAGCCGAATCGCCGATACGGAGCAGGTCGACTATTTGATTCTTGCC
GTCGGGACACCGAGCAAGTCGGATGGAAGCTGTGACTTATCTTATATCGAAGCAGTCTTGTCGGAACTAAACACGAAGCA
TAAAATCGTCATTCGTAGCTCGGTCCCACCCGGCACGACAGATTTACTGAACATCATGTATCCCTCTCATACGTTTGCGA
TCGTACCGGAATTTTTACAAGAAGGACGCGCGCTCGCAGATGTCATGAAACCACACCGGGTCGTCATCGGGTGTGAAAAC
CTCGAAGTCGCAGAAGAGTTGGCAGGCATCTATGGACGCCTTGGCGTTCCGCTCATCTGTACGACACCGATCAACGCAGA
ACTCATCAAATACGCCTCGAACGCCTTTTTGGCCACGAAAATCAGCTTCATGAACGACTTGTCGCGTCTAGCCGATCAAG
CTGGCGCTGACATTTCGACGATTGCGGACGGGATGGGACTCGACCCACGAATCGGACGTTCGTTCTTGAACGCGGGCATC
GGATACGGAGGTTCGTGTTTCCCGAAAGATATGAACGCACTTCTTCACGTCGCAAGTGAGAACGAAATCGACCTACGTGT
CATCCGCGCGGCAGCGAAAGTGAATGAGACGCAAATCGAGTACGTGCTCTCGAAATTGAACGTTGAACCGAACATGCGCG
TGGCTATCCTTGGTTTGGCATTCAAACCGGGAACGGACGATATGCGGGATGCCCCGTCGATTCTCCTCGCTCACCATATG
GTGGCCCGTAACGTGGACGTCATTGGGTATGACCCGATTGCGACGTGGGACTACCCACAAGCGACGACCGTCGAAGAGGC
GCTGAAGGGAGCCGATTATGCCATTCTCGTCACAGAATGGGACGAGATCGTGAATTTGGCACCGGATGCTTTCAGCGGCA
TGCGCCAGCGTCGATTGATCGATGCACGGAACGCATGGAAGTTCGTACGCGATCCAGGCGCTGTGTCGTACGAAGGAATC
GGACGGATGCAACGTCCGTCGAACACACCGACTTCAAACTAA

Upstream 100 bases:

>100_bases
TTGACTCATTATAGCAAAGAACATCCAGAGAGTGTTAGAAGCTTCACTTCTTGGGCGTGTTTCGGTACGCTTATAAAAGA
TGATTGAAGGAGGAACTGAT

Downstream 100 bases:

>100_bases
ACCTGTTCAGGACCGCTCATGTAGGCGGTCCTGTTTTTGTGTGGGATGAATCTTTTGCGTGACTCATGACGTATAGAAAG
AAGAGGAGGTGAGGCACATG

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKFGIIGLGYVGLATLCGLAKAGHHVIGVEADEEKLRLLMSGHPPFHEPGMAEVLQEHADQITLTSRIADTEQVDYLILA
VGTPSKSDGSCDLSYIEAVLSELNTKHKIVIRSSVPPGTTDLLNIMYPSHTFAIVPEFLQEGRALADVMKPHRVVIGCEN
LEVAEELAGIYGRLGVPLICTTPINAELIKYASNAFLATKISFMNDLSRLADQAGADISTIADGMGLDPRIGRSFLNAGI
GYGGSCFPKDMNALLHVASENEIDLRVIRAAAKVNETQIEYVLSKLNVEPNMRVAILGLAFKPGTDDMRDAPSILLAHHM
VARNVDVIGYDPIATWDYPQATTVEEALKGADYAILVTEWDEIVNLAPDAFSGMRQRRLIDARNAWKFVRDPGAVSYEGI
GRMQRPSNTPTSN

Sequences:

>Translated_413_residues
MKFGIIGLGYVGLATLCGLAKAGHHVIGVEADEEKLRLLMSGHPPFHEPGMAEVLQEHADQITLTSRIADTEQVDYLILA
VGTPSKSDGSCDLSYIEAVLSELNTKHKIVIRSSVPPGTTDLLNIMYPSHTFAIVPEFLQEGRALADVMKPHRVVIGCEN
LEVAEELAGIYGRLGVPLICTTPINAELIKYASNAFLATKISFMNDLSRLADQAGADISTIADGMGLDPRIGRSFLNAGI
GYGGSCFPKDMNALLHVASENEIDLRVIRAAAKVNETQIEYVLSKLNVEPNMRVAILGLAFKPGTDDMRDAPSILLAHHM
VARNVDVIGYDPIATWDYPQATTVEEALKGADYAILVTEWDEIVNLAPDAFSGMRQRRLIDARNAWKFVRDPGAVSYEGI
GRMQRPSNTPTSN
>Mature_413_residues
MKFGIIGLGYVGLATLCGLAKAGHHVIGVEADEEKLRLLMSGHPPFHEPGMAEVLQEHADQITLTSRIADTEQVDYLILA
VGTPSKSDGSCDLSYIEAVLSELNTKHKIVIRSSVPPGTTDLLNIMYPSHTFAIVPEFLQEGRALADVMKPHRVVIGCEN
LEVAEELAGIYGRLGVPLICTTPINAELIKYASNAFLATKISFMNDLSRLADQAGADISTIADGMGLDPRIGRSFLNAGI
GYGGSCFPKDMNALLHVASENEIDLRVIRAAAKVNETQIEYVLSKLNVEPNMRVAILGLAFKPGTDDMRDAPSILLAHHM
VARNVDVIGYDPIATWDYPQATTVEEALKGADYAILVTEWDEIVNLAPDAFSGMRQRRLIDARNAWKFVRDPGAVSYEGI
GRMQRPSNTPTSN

Specific function: Catalyzes the conversion of UDP-glucose into UDP- glucuronate, one of the precursors of teichuronic acid [H]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=414, Percent_Identity=29.7101449275362, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI296040438, Length=317, Percent_Identity=30.2839116719243, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI296040443, Length=397, Percent_Identity=27.7078085642317, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1788340, Length=350, Percent_Identity=31.1428571428571, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI48994968, Length=427, Percent_Identity=25.0585480093677, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17560350, Length=421, Percent_Identity=30.6413301662708, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17136908, Length=423, Percent_Identity=32.387706855792, Blast_Score=169, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 44866; Mature: 44866

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGIIGLGYVGLATLCGLAKAGHHVIGVEADEEKLRLLMSGHPPFHEPGMAEVLQEHAD
CCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHC
QITLTSRIADTEQVDYLILAVGTPSKSDGSCDLSYIEAVLSELNTKHKIVIRSSVPPGTT
CEEEHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
DLLNIMYPSHTFAIVPEFLQEGRALADVMKPHRVVIGCENLEVAEELAGIYGRLGVPLIC
HHHHEECCCCHHHHHHHHHHCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
TTPINAELIKYASNAFLATKISFMNDLSRLADQAGADISTIADGMGLDPRIGRSFLNAGI
ECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCC
GYGGSCFPKDMNALLHVASENEIDLRVIRAAAKVNETQIEYVLSKLNVEPNMRVAILGLA
CCCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEE
FKPGTDDMRDAPSILLAHHMVARNVDVIGYDPIATWDYPQATTVEEALKGADYAILVTEW
ECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCEEEEEECH
DEIVNLAPDAFSGMRQRRLIDARNAWKFVRDPGAVSYEGIGRMQRPSNTPTSN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFGIIGLGYVGLATLCGLAKAGHHVIGVEADEEKLRLLMSGHPPFHEPGMAEVLQEHAD
CCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHC
QITLTSRIADTEQVDYLILAVGTPSKSDGSCDLSYIEAVLSELNTKHKIVIRSSVPPGTT
CEEEHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
DLLNIMYPSHTFAIVPEFLQEGRALADVMKPHRVVIGCENLEVAEELAGIYGRLGVPLIC
HHHHEECCCCHHHHHHHHHHCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
TTPINAELIKYASNAFLATKISFMNDLSRLADQAGADISTIADGMGLDPRIGRSFLNAGI
ECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCC
GYGGSCFPKDMNALLHVASENEIDLRVIRAAAKVNETQIEYVLSKLNVEPNMRVAILGLA
CCCCCCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEE
FKPGTDDMRDAPSILLAHHMVARNVDVIGYDPIATWDYPQATTVEEALKGADYAILVTEW
ECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCEEEEEECH
DEIVNLAPDAFSGMRQRRLIDARNAWKFVRDPGAVSYEGIGRMQRPSNTPTSN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]