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The map label for this gene is yvrH [H]

Identifier: 229916895

GI number: 229916895

Start: 1136137

End: 1136826

Strand: Direct

Name: yvrH [H]

Synonym: EAT1b_1168

Alternate gene names: 229916895

Gene position: 1136137-1136826 (Clockwise)

Preceding gene: 229916891

Following gene: 229916896

Centisome position: 37.87

GC content: 52.46

Gene sequence:

>690_bases
ATGGAACAGCCACGGATTCTCATCGTGGATGATGAACAAGATTTATGTACGTTGATTCAACGCGCGCTTGAAAAGGAAGG
ATTTCATGAGATTCGGACCGCTCATACGTTGAAGGACGGATTTGATGTCTTCGAAACGTTCCGCCCACACTTGGCAATCT
TAGACGTCATGTTGCCGGACGGGGAAGGCTATCAGCTCTGCCAACAGATGCGGGCGCAGTCCAATATCCCGATCCTCTTC
CTATCTGCCAAATCGGAAGAAGTCGACAAACTGCTCGGCCTTGCCATCGGTGGAGATGACTACATCACGAAGCCGTTCAG
CCCAAAAGAAGTGGCATTCCGCGTAAAGGCACAGCTTCGACGAGTGTCGATGATGGAAGCTCCGGTGGCCGAGACGACGA
CCGTCGGCCCCTTTCAAATGAATGAAGACGAGACGGAAGTGTATGTGAACGGGGAACGATTGGAGTTGACGGCTAAAGAA
GTCGGTCTCCTCGCCTGCTTTTTACGCAACCCGAACCGGATTCTCAGCAAAGAGACGCTCTTCACGCAAGTGTGGGGCGA
GTCGTTCTTCGGGTCGGACAACACCGTCATGGTCCACATCCGACGTCTCCGTGAAAAAGTCGAACCGAATCCATCCGAGC
CGACTTATATCAAGACGGTCAAGGGACTTGGCTATCGGTTGACGGTATAA

Upstream 100 bases:

>100_bases
CACCTCTTTCTGTCCCTTACATTACGCCCCCTGTCTTAACTCCAACTCACGCGTACCTTACAAAATCCTTACATGATATG
CTTAGAACGAGGTGATGACG

Downstream 100 bases:

>100_bases
AGGAGCGATCATGATGAAATGGAAACTGACCGGTCGCTATTTGTTGTCAATCCTCCTCATTGTGGCGCTCGTTGTCTTCT
TAAACATTACGATTTTGTTC

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MEQPRILIVDDEQDLCTLIQRALEKEGFHEIRTAHTLKDGFDVFETFRPHLAILDVMLPDGEGYQLCQQMRAQSNIPILF
LSAKSEEVDKLLGLAIGGDDYITKPFSPKEVAFRVKAQLRRVSMMEAPVAETTTVGPFQMNEDETEVYVNGERLELTAKE
VGLLACFLRNPNRILSKETLFTQVWGESFFGSDNTVMVHIRRLREKVEPNPSEPTYIKTVKGLGYRLTV

Sequences:

>Translated_229_residues
MEQPRILIVDDEQDLCTLIQRALEKEGFHEIRTAHTLKDGFDVFETFRPHLAILDVMLPDGEGYQLCQQMRAQSNIPILF
LSAKSEEVDKLLGLAIGGDDYITKPFSPKEVAFRVKAQLRRVSMMEAPVAETTTVGPFQMNEDETEVYVNGERLELTAKE
VGLLACFLRNPNRILSKETLFTQVWGESFFGSDNTVMVHIRRLREKVEPNPSEPTYIKTVKGLGYRLTV
>Mature_229_residues
MEQPRILIVDDEQDLCTLIQRALEKEGFHEIRTAHTLKDGFDVFETFRPHLAILDVMLPDGEGYQLCQQMRAQSNIPILF
LSAKSEEVDKLLGLAIGGDDYITKPFSPKEVAFRVKAQLRRVSMMEAPVAETTTVGPFQMNEDETEVYVNGERLELTAKE
VGLLACFLRNPNRILSKETLFTQVWGESFFGSDNTVMVHIRRLREKVEPNPSEPTYIKTVKGLGYRLTV

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=38.695652173913, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=38.5281385281385, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=37.6106194690265, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=34.8214285714286, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.4763948497854, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=34.8017621145374, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.7354260089686, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=31.6742081447964, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=30.2631578947368, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=30.7017543859649, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=26.4957264957265, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=28.9256198347107, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26064; Mature: 26064

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPRILIVDDEQDLCTLIQRALEKEGFHEIRTAHTLKDGFDVFETFRPHLAILDVMLPD
CCCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GEGYQLCQQMRAQSNIPILFLSAKSEEVDKLLGLAIGGDDYITKPFSPKEVAFRVKAQLR
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHH
RVSMMEAPVAETTTVGPFQMNEDETEVYVNGERLELTAKEVGLLACFLRNPNRILSKETL
HHHHHHCCCCCCCCCCCEEECCCCCEEEECCCEEEEEHHHHHHHHHHHCCCHHHHHHHHH
FTQVWGESFFGSDNTVMVHIRRLREKVEPNPSEPTYIKTVKGLGYRLTV
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure
MEQPRILIVDDEQDLCTLIQRALEKEGFHEIRTAHTLKDGFDVFETFRPHLAILDVMLPD
CCCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GEGYQLCQQMRAQSNIPILFLSAKSEEVDKLLGLAIGGDDYITKPFSPKEVAFRVKAQLR
CCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHH
RVSMMEAPVAETTTVGPFQMNEDETEVYVNGERLELTAKEVGLLACFLRNPNRILSKETL
HHHHHHCCCCCCCCCCCEEECCCCCEEEECCCEEEEEHHHHHHHHHHHCCCHHHHHHHHH
FTQVWGESFFGSDNTVMVHIRRLREKVEPNPSEPTYIKTVKGLGYRLTV
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]