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The map label for this gene is lacA [H]

Identifier: 229916775

GI number: 229916775

Start: 996150

End: 996569

Strand: Reverse

Name: lacA [H]

Synonym: EAT1b_1048

Alternate gene names: 229916775

Gene position: 996569-996150 (Counterclockwise)

Preceding gene: 229916776

Following gene: 229916774

Centisome position: 33.22

GC content: 48.81

Gene sequence:

>420_bases
GTGAAAGTAGCACTTTCGGCAGACAAAGCGAGTGAAGGGCGTAAGCAACTGATCGTGAACCATATGGAGGAACTCGGACA
TGAAGTCGTAGATTATTCGGGTGATGACGTCGTGGCAGCGATTGTTCGAGTGACGGATGCGGTTCGCGATGGAGAGGCAG
CTCGAGGCATCTTACTCGATTCCTTTGGATCATTGTCCTACATGGTCGCGGCGAAACAATCTGGAATTGTTTGTGCACAA
GTATCAGATGAACATTCTGCGAAAATGACACGAGATCATAACAACTCTACGATCATCGCGATGGGGACGGAAGTCATCGG
TGATACGTTGGCACGTGAAATTGTAAGCGCATTCCTTGGAGCGGAGTACTCGGGTGGGCGTCATCAAATTCGCGTAGACA
TGTTGAACAAATTGGCTTAA

Upstream 100 bases:

>100_bases
AACAAATAATGTTCGAAAATGATTGAAAATAATCGAACTTGTGCTATTATAAAAGTGTAAATAACGAACAAAAAAGAACA
AAAAGAAAGAAGGGATTGTT

Downstream 100 bases:

>100_bases
GGAGGACGAACAGGATGAAGATTGCAATCGGTTGCGACCATATTGTGACAGATATTAAAGATGAGATGGTGCAGTACCTT
GAAGCGCAAGGCCATGAAGT

Product: sugar-phosphate isomerase, RpiB/LacA/LacB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKVALSADKASEGRKQLIVNHMEELGHEVVDYSGDDVVAAIVRVTDAVRDGEAARGILLDSFGSLSYMVAAKQSGIVCAQ
VSDEHSAKMTRDHNNSTIIAMGTEVIGDTLAREIVSAFLGAEYSGGRHQIRVDMLNKLA

Sequences:

>Translated_139_residues
MKVALSADKASEGRKQLIVNHMEELGHEVVDYSGDDVVAAIVRVTDAVRDGEAARGILLDSFGSLSYMVAAKQSGIVCAQ
VSDEHSAKMTRDHNNSTIIAMGTEVIGDTLAREIVSAFLGAEYSGGRHQIRVDMLNKLA
>Mature_139_residues
MKVALSADKASEGRKQLIVNHMEELGHEVVDYSGDDVVAAIVRVTDAVRDGEAARGILLDSFGSLSYMVAAKQSGIVCAQ
VSDEHSAKMTRDHNNSTIIAMGTEVIGDTLAREIVSAFLGAEYSGGRHQIRVDMLNKLA

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=142, Percent_Identity=37.3239436619718, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004783
- InterPro:   IPR003500 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: =5.3.1.26 [H]

Molecular weight: Translated: 14874; Mature: 14874

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVALSADKASEGRKQLIVNHMEELGHEVVDYSGDDVVAAIVRVTDAVRDGEAARGILLD
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
SFGSLSYMVAAKQSGIVCAQVSDEHSAKMTRDHNNSTIIAMGTEVIGDTLAREIVSAFLG
CCCCCEEEEEECCCCEEEEEECCCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHC
AEYSGGRHQIRVDMLNKLA
CCCCCCCEEEEHHHHHHCC
>Mature Secondary Structure
MKVALSADKASEGRKQLIVNHMEELGHEVVDYSGDDVVAAIVRVTDAVRDGEAARGILLD
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
SFGSLSYMVAAKQSGIVCAQVSDEHSAKMTRDHNNSTIIAMGTEVIGDTLAREIVSAFLG
CCCCCEEEEEECCCCEEEEEECCCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHC
AEYSGGRHQIRVDMLNKLA
CCCCCCCEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]