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The map label for this gene is arsA [H]

Identifier: 229916754

GI number: 229916754

Start: 974685

End: 976442

Strand: Reverse

Name: arsA [H]

Synonym: EAT1b_1027

Alternate gene names: 229916754

Gene position: 976442-974685 (Counterclockwise)

Preceding gene: 229916755

Following gene: 229916753

Centisome position: 32.55

GC content: 52.96

Gene sequence:

>1758_bases
ATGAATCGCTTTGATTTCATGACCATTCGCCCGACCCGTTATGTGTTCTTGACCGGGAAAGGTGGCGTCGGGAAGACATC
GACAGCGTCAAGCCTCGCCCTGACGCTCGCCGACCGTGGCAAGCGTGTCTTACTCGTTTCGACCGACCCGGCTAGTAATT
TACAAGACGTGTTTGAGATGGAACTCGATGAGACGCCGCGCCTCGTTCCGGAAACAAAGCTTGCCATCGCCAACTTCGAT
CCGGAAGAAGCGGCAAAACAATATATGGAACGCATGGTCGGACCTTATCGAGGTGTATTGCCGGACGTGGCCATTCAATC
GATGGAAGAGCAATTATCCGGTGCCTGTACAATTGAGATTGCGGCATTTGACCAATTTACGGACTTGTTGACGTCCGTGT
CAGCCCGTGAGACGTACGATCACGTCATCTTTGACACGGCACCGACCGGTCATACGTTGCGCCTACTCACCTTGCCGAGT
GCATGGGATGAATTTTTGGAGACGAACACGACAGGTGCGTCTTGCCTTGGTCCGCTTGCCGGTTTAGCTGACAAACAAAT
GCAGTACAAAAAGGCCGTTGAGACGCTCACTGATGGTAAAGAGACGACGCTGCTTCTCGTTGCCCGTCCCGAAACATCCA
CGCTCATCGAAGCGGAGCGTGCCGCGACCGAACTTCGCGCCATCGGCATCGAGCAAATGCAGCTCATCGTCAACGGTCTT
GTCCAACAGGATGAACGGGCAGACCGATACACGAAGCGGCTCATCGAGCGTCAGCAACAAGCACTCCGTGAACTTCCTGA
AGGCATAACTGACCTCGAGGCATTCAAACTTCCATATGCTTACGAAAATCTGATTGGTGTCTCTGCACTTCGGCGCTTTG
TGAACGGAGAGACGGTCGCTGTCGCAAATGCATGCTATGACTCGAGTCGTTACGGATCACTTGATCGACTCGTTGACGAG
ATTGAGGCGGACGGTCCAAGTGTCATCATGACGATGGGGAAAGGTGGCGTCGGGAAGACGACACTCGCTTCGCTGATTGC
GGTCGCGCTTCATGAAAGAGGGCACTCTGTTCATTTGACGACGACGGATCCGGCCGCTCATGTCGCTTTCACGATTGGGA
CAAACATTGCAGATACGTTCACGGTCGATGCCATTGACCCGAAAGTTGAAATTGAGAGGTATCGACAGGATGTGTTCAAG
GAAGCAGGGGACCTGAATGAAGAGCAACGTATGATGCTCGAAGAGGACCTGCGTTCGCCGTGCACCGAAGAAATCGCCGT
TTTCCGTGCCTTTGCGAATCAGGTGGCGAAAGCGAAAGATTGTTTCGTCGTCATCGATACGGCACCGACCGGACACACGC
TTCTTCTGTTAGATGCGACCGAGAGTTATCATCGCGAACTCGAACGCTCGACTGGCGTTGTCCCGGAAGCAGTCCGAGAT
TTGTTGCCGAAATTACGTGACCCGAAACAAACGCACGTCATCATCACGACCTTGCCTGAAGCGACACCGGTATATGAAGC
TGAACGACTCGTAGCAGATTTGAATCGGGCTAAGATTCTACCGTTCGCTTGGGTCGTTAATCAATCGTTCACGCCACTCG
ATGTCACGAGCAAACTATTGACCGCGAAAGTCGCGAATGAAGTTCCATGGCTCGAACGTGTGAACAGCTATCGGCGTCCG
ACGATGCTCGCCTGGCAAGAACATTTGCCGGTCGGATATTCCGCGTTATCCCAACTATTGAAGGAGGAAGTGAAATGA

Upstream 100 bases:

>100_bases
TTGCTAGTTTGTTCGACCTTCCGATTGAGGCGTTCGCTGTGCAAGATGGTGAGAAGCCAAAAGTCCGTATTACATTAAAA
AAATAAGGAGGCGTATCACG

Downstream 100 bases:

>100_bases
AGATTACGAATGAAGCCATCGATTACTTAAAAACAGCGCTAGAGGAAGAGCAGACAAAATCAGTCCGCATCATCACGGAG
GCTGGTTGCTGTGGACCGAC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNRFDFMTIRPTRYVFLTGKGGVGKTSTASSLALTLADRGKRVLLVSTDPASNLQDVFEMELDETPRLVPETKLAIANFD
PEEAAKQYMERMVGPYRGVLPDVAIQSMEEQLSGACTIEIAAFDQFTDLLTSVSARETYDHVIFDTAPTGHTLRLLTLPS
AWDEFLETNTTGASCLGPLAGLADKQMQYKKAVETLTDGKETTLLLVARPETSTLIEAERAATELRAIGIEQMQLIVNGL
VQQDERADRYTKRLIERQQQALRELPEGITDLEAFKLPYAYENLIGVSALRRFVNGETVAVANACYDSSRYGSLDRLVDE
IEADGPSVIMTMGKGGVGKTTLASLIAVALHERGHSVHLTTTDPAAHVAFTIGTNIADTFTVDAIDPKVEIERYRQDVFK
EAGDLNEEQRMMLEEDLRSPCTEEIAVFRAFANQVAKAKDCFVVIDTAPTGHTLLLLDATESYHRELERSTGVVPEAVRD
LLPKLRDPKQTHVIITTLPEATPVYEAERLVADLNRAKILPFAWVVNQSFTPLDVTSKLLTAKVANEVPWLERVNSYRRP
TMLAWQEHLPVGYSALSQLLKEEVK

Sequences:

>Translated_585_residues
MNRFDFMTIRPTRYVFLTGKGGVGKTSTASSLALTLADRGKRVLLVSTDPASNLQDVFEMELDETPRLVPETKLAIANFD
PEEAAKQYMERMVGPYRGVLPDVAIQSMEEQLSGACTIEIAAFDQFTDLLTSVSARETYDHVIFDTAPTGHTLRLLTLPS
AWDEFLETNTTGASCLGPLAGLADKQMQYKKAVETLTDGKETTLLLVARPETSTLIEAERAATELRAIGIEQMQLIVNGL
VQQDERADRYTKRLIERQQQALRELPEGITDLEAFKLPYAYENLIGVSALRRFVNGETVAVANACYDSSRYGSLDRLVDE
IEADGPSVIMTMGKGGVGKTTLASLIAVALHERGHSVHLTTTDPAAHVAFTIGTNIADTFTVDAIDPKVEIERYRQDVFK
EAGDLNEEQRMMLEEDLRSPCTEEIAVFRAFANQVAKAKDCFVVIDTAPTGHTLLLLDATESYHRELERSTGVVPEAVRD
LLPKLRDPKQTHVIITTLPEATPVYEAERLVADLNRAKILPFAWVVNQSFTPLDVTSKLLTAKVANEVPWLERVNSYRRP
TMLAWQEHLPVGYSALSQLLKEEVK
>Mature_585_residues
MNRFDFMTIRPTRYVFLTGKGGVGKTSTASSLALTLADRGKRVLLVSTDPASNLQDVFEMELDETPRLVPETKLAIANFD
PEEAAKQYMERMVGPYRGVLPDVAIQSMEEQLSGACTIEIAAFDQFTDLLTSVSARETYDHVIFDTAPTGHTLRLLTLPS
AWDEFLETNTTGASCLGPLAGLADKQMQYKKAVETLTDGKETTLLLVARPETSTLIEAERAATELRAIGIEQMQLIVNGL
VQQDERADRYTKRLIERQQQALRELPEGITDLEAFKLPYAYENLIGVSALRRFVNGETVAVANACYDSSRYGSLDRLVDE
IEADGPSVIMTMGKGGVGKTTLASLIAVALHERGHSVHLTTTDPAAHVAFTIGTNIADTFTVDAIDPKVEIERYRQDVFK
EAGDLNEEQRMMLEEDLRSPCTEEIAVFRAFANQVAKAKDCFVVIDTAPTGHTLLLLDATESYHRELERSTGVVPEAVRD
LLPKLRDPKQTHVIITTLPEATPVYEAERLVADLNRAKILPFAWVVNQSFTPLDVTSKLLTAKVANEVPWLERVNSYRRP
TMLAWQEHLPVGYSALSQLLKEEVK

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=316, Percent_Identity=28.7974683544304, Blast_Score=78, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17557003, Length=318, Percent_Identity=29.874213836478, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320103, Length=297, Percent_Identity=29.96632996633, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24586297, Length=303, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003593
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 64877; Mature: 64877

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFDFMTIRPTRYVFLTGKGGVGKTSTASSLALTLADRGKRVLLVSTDPASNLQDVFEM
CCCCEEEEECCCEEEEEECCCCCCCCCCHHHHEEEEECCCCEEEEEECCCCCHHHHHHHH
ELDETPRLVPETKLAIANFDPEEAAKQYMERMVGPYRGVLPDVAIQSMEEQLSGACTIEI
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
AAFDQFTDLLTSVSARETYDHVIFDTAPTGHTLRLLTLPSAWDEFLETNTTGASCLGPLA
EHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHH
GLADKQMQYKKAVETLTDGKETTLLLVARPETSTLIEAERAATELRAIGIEQMQLIVNGL
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQDERADRYTKRLIERQQQALRELPEGITDLEAFKLPYAYENLIGVSALRRFVNGETVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEE
VANACYDSSRYGSLDRLVDEIEADGPSVIMTMGKGGVGKTTLASLIAVALHERGHSVHLT
EEHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEE
TTDPAAHVAFTIGTNIADTFTVDAIDPKVEIERYRQDVFKEAGDLNEEQRMMLEEDLRSP
ECCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
CTEEIAVFRAFANQVAKAKDCFVVIDTAPTGHTLLLLDATESYHRELERSTGVVPEAVRD
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHH
LLPKLRDPKQTHVIITTLPEATPVYEAERLVADLNRAKILPFAWVVNQSFTPLDVTSKLL
HHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHH
TAKVANEVPWLERVNSYRRPTMLAWQEHLPVGYSALSQLLKEEVK
HHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNRFDFMTIRPTRYVFLTGKGGVGKTSTASSLALTLADRGKRVLLVSTDPASNLQDVFEM
CCCCEEEEECCCEEEEEECCCCCCCCCCHHHHEEEEECCCCEEEEEECCCCCHHHHHHHH
ELDETPRLVPETKLAIANFDPEEAAKQYMERMVGPYRGVLPDVAIQSMEEQLSGACTIEI
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
AAFDQFTDLLTSVSARETYDHVIFDTAPTGHTLRLLTLPSAWDEFLETNTTGASCLGPLA
EHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHH
GLADKQMQYKKAVETLTDGKETTLLLVARPETSTLIEAERAATELRAIGIEQMQLIVNGL
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQDERADRYTKRLIERQQQALRELPEGITDLEAFKLPYAYENLIGVSALRRFVNGETVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEE
VANACYDSSRYGSLDRLVDEIEADGPSVIMTMGKGGVGKTTLASLIAVALHERGHSVHLT
EEHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEE
TTDPAAHVAFTIGTNIADTFTVDAIDPKVEIERYRQDVFKEAGDLNEEQRMMLEEDLRSP
ECCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
CTEEIAVFRAFANQVAKAKDCFVVIDTAPTGHTLLLLDATESYHRELERSTGVVPEAVRD
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHH
LLPKLRDPKQTHVIITTLPEATPVYEAERLVADLNRAKILPFAWVVNQSFTPLDVTSKLL
HHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHH
TAKVANEVPWLERVNSYRRPTMLAWQEHLPVGYSALSQLLKEEVK
HHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9464374 [H]