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The map label for this gene is yhcK [H]

Identifier: 229916749

GI number: 229916749

Start: 969625

End: 970761

Strand: Direct

Name: yhcK [H]

Synonym: EAT1b_1022

Alternate gene names: 229916749

Gene position: 969625-970761 (Clockwise)

Preceding gene: 229916738

Following gene: 229916757

Centisome position: 32.32

GC content: 44.68

Gene sequence:

>1137_bases
TTGCTGTCACTTACAACCTTAATTAATAACCTAATTGCCAATGCGAGCCTTTTGCTCGTGGGCCTGTATCTAATTTCACG
TTTCACGAAGCTTGGTTTCACGAATAAATTGCCAATTCGTCGGCGCATCACCATCTCCATCCTCTTGGCCGGACTCTCCA
TGCTCATCACCCTTCATGGTGTGCTATGGAACGCCCAAGCGGACTTCCAGTATGGATTCATTCCGCTCATCATCTCTGCC
TTATACTTTGGGATTTCTGGGTTACGCATTACGTATGTGACGAGTATCATTCTCCTTCCGTTCATCGTACCTGGAGAGAC
GCTTCTGATCATCACGCTCCTCGACTACTCTGTCGCGGCAGGTATCGCATTCTTATTTTTACGAAGACGTGAACGAATCA
AACCGACTCAAGATATCCGAACTGTCAACATGATTAGCCTTACATGTATCGCACTTTTCTCTGCATTCAACATGGCCAAT
TACGAAGAACCAAGCGCATATGTTATCACACTCATTTGGTTTTTATTTATCGGATACGCAACAGGTTTGTTCTTACACAT
CGTATATGGCGGAATTCGCAAAATCGAACGGTCTCGACGTTTGATCACAAAGTATAAAGAGGCTGCGTATACGGATACGT
TGACTGGTCTAGGGAATCGGAGACAATTTGACGAAGAAATGAAACGAGTCGATGAAGAAGTGTTTACGTCACCGCATGAG
ATTGCGTTGTTGTTAATCGATATCGATCACTTTAAATCAGTCAATGATACATACGGACACGATGCAGGTGATGCGATTTT
AGTAGAACTCGGTCAGCGTCTCTCTGGAATCGCACGAGCAGATGACATGGTATGCCGAAACGGCGGGGAGGAGTTCTCTG
TTTTACTTGCCGATTGTAACCTTCCACAAGCCATATCAATTGCGAATCGATATTTGACCGAAGTCTCGAAACAACCTTTT
CAATTGCCTGATGAAGCGATGCTGGATGTCACCATTTCAATCGGAGTATCGAGCACTTCTGAACGAAAAGTCATCACGTC
CGCTCAACTGATTAAAAAGGCAGACATTGGGCTTTATGTCGCCAAACGGAATGGGCGAAATCGAATCGGAAAATGGAATC
AACGGAAAGCCAACTAA

Upstream 100 bases:

>100_bases
GTTATTTTAGTAAAGTAGAGCACTAAACATCTTTCCTCTACAAAAAGGATTGCTTTCCGAGAGTTCAATCTGTATATAGA
AGTTAAGGAGGAAAAAATAG

Downstream 100 bases:

>100_bases
CCTCTCACACGTGTGTGAGAGGTTCTTTCATAACTTATTCCATCTCTCAAGCGATTCCAAATACCACCGATAGCTCATCT
TGATTTCTTCATCTGTTAAG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLSLTTLINNLIANASLLLVGLYLISRFTKLGFTNKLPIRRRITISILLAGLSMLITLHGVLWNAQADFQYGFIPLIISA
LYFGISGLRITYVTSIILLPFIVPGETLLIITLLDYSVAAGIAFLFLRRRERIKPTQDIRTVNMISLTCIALFSAFNMAN
YEEPSAYVITLIWFLFIGYATGLFLHIVYGGIRKIERSRRLITKYKEAAYTDTLTGLGNRRQFDEEMKRVDEEVFTSPHE
IALLLIDIDHFKSVNDTYGHDAGDAILVELGQRLSGIARADDMVCRNGGEEFSVLLADCNLPQAISIANRYLTEVSKQPF
QLPDEAMLDVTISIGVSSTSERKVITSAQLIKKADIGLYVAKRNGRNRIGKWNQRKAN

Sequences:

>Translated_378_residues
MLSLTTLINNLIANASLLLVGLYLISRFTKLGFTNKLPIRRRITISILLAGLSMLITLHGVLWNAQADFQYGFIPLIISA
LYFGISGLRITYVTSIILLPFIVPGETLLIITLLDYSVAAGIAFLFLRRRERIKPTQDIRTVNMISLTCIALFSAFNMAN
YEEPSAYVITLIWFLFIGYATGLFLHIVYGGIRKIERSRRLITKYKEAAYTDTLTGLGNRRQFDEEMKRVDEEVFTSPHE
IALLLIDIDHFKSVNDTYGHDAGDAILVELGQRLSGIARADDMVCRNGGEEFSVLLADCNLPQAISIANRYLTEVSKQPF
QLPDEAMLDVTISIGVSSTSERKVITSAQLIKKADIGLYVAKRNGRNRIGKWNQRKAN
>Mature_378_residues
MLSLTTLINNLIANASLLLVGLYLISRFTKLGFTNKLPIRRRITISILLAGLSMLITLHGVLWNAQADFQYGFIPLIISA
LYFGISGLRITYVTSIILLPFIVPGETLLIITLLDYSVAAGIAFLFLRRRERIKPTQDIRTVNMISLTCIALFSAFNMAN
YEEPSAYVITLIWFLFIGYATGLFLHIVYGGIRKIERSRRLITKYKEAAYTDTLTGLGNRRQFDEEMKRVDEEVFTSPHE
IALLLIDIDHFKSVNDTYGHDAGDAILVELGQRLSGIARADDMVCRNGGEEFSVLLADCNLPQAISIANRYLTEVSKQPF
QLPDEAMLDVTISIGVSSTSERKVITSAQLIKKADIGLYVAKRNGRNRIGKWNQRKAN

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=186, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082007, Length=202, Percent_Identity=33.6633663366337, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081881, Length=191, Percent_Identity=37.696335078534, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786584, Length=225, Percent_Identity=29.7777777777778, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=34.1614906832298, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=33.125, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=35.4430379746835, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787541, Length=180, Percent_Identity=29.4444444444444, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787056, Length=176, Percent_Identity=32.9545454545455, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788085, Length=206, Percent_Identity=30.5825242718447, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081974, Length=169, Percent_Identity=28.9940828402367, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 42377; Mature: 42377

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTTLINNLIANASLLLVGLYLISRFTKLGFTNKLPIRRRITISILLAGLSMLITLHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLWNAQADFQYGFIPLIISALYFGISGLRITYVTSIILLPFIVPGETLLIITLLDYSVAA
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
GIAFLFLRRRERIKPTQDIRTVNMISLTCIALFSAFNMANYEEPSAYVITLIWFLFIGYA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TGLFLHIVYGGIRKIERSRRLITKYKEAAYTDTLTGLGNRRQFDEEMKRVDEEVFTSPHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
IALLLIDIDHFKSVNDTYGHDAGDAILVELGQRLSGIARADDMVCRNGGEEFSVLLADCN
EEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
LPQAISIANRYLTEVSKQPFQLPDEAMLDVTISIGVSSTSERKVITSAQLIKKADIGLYV
CCHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
AKRNGRNRIGKWNQRKAN
EECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSLTTLINNLIANASLLLVGLYLISRFTKLGFTNKLPIRRRITISILLAGLSMLITLHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLWNAQADFQYGFIPLIISALYFGISGLRITYVTSIILLPFIVPGETLLIITLLDYSVAA
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
GIAFLFLRRRERIKPTQDIRTVNMISLTCIALFSAFNMANYEEPSAYVITLIWFLFIGYA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TGLFLHIVYGGIRKIERSRRLITKYKEAAYTDTLTGLGNRRQFDEEMKRVDEEVFTSPHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
IALLLIDIDHFKSVNDTYGHDAGDAILVELGQRLSGIARADDMVCRNGGEEFSVLLADCN
EEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
LPQAISIANRYLTEVSKQPFQLPDEAMLDVTISIGVSSTSERKVITSAQLIKKADIGLYV
CCHHHHHHHHHHHHHCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
AKRNGRNRIGKWNQRKAN
EECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]