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The map label for this gene is treR [H]

Identifier: 229916668

GI number: 229916668

Start: 889248

End: 889955

Strand: Reverse

Name: treR [H]

Synonym: EAT1b_0940

Alternate gene names: 229916668

Gene position: 889955-889248 (Counterclockwise)

Preceding gene: 229916669

Following gene: 229916667

Centisome position: 29.67

GC content: 50.28

Gene sequence:

>708_bases
ATGGCGAAATATCGCCAAATCTTTGAGCGTCTGGCAGAAGAGATGCGAAATGGAACAAGACCCGCTGACTCAAAGCTTCC
GTCTGAGACCGAGTTGATGCATCAGTTCGAGGCTAGCCGGGGAACCGTCCGAAAAGCGCTCGATCTTTTACAGGAAAACG
GGTATGTCCGGAAGCATCACGGAAAAGGCGTGTTCGTATTGAAACGGGACCAGATCGAGTTTCAATTCAACGGCATCGTC
AGTTTCTCAGAAGTGTACGCGAGCATGCTCGGTCGTTCTATTCAGACCCATGTCGCTTCGTTTGAAGAGATGGAGGCCCC
GACTTGGCTTGCCGAACGGATGAATTTGGCGACAGGGACGCACGTGTTTCGCATCGAACGGGTTCGGAACTTTGACGGGG
AGAACGTCATCTTAGATATCAACTATTTCGTCAAAGACCTCGTCCCTGGATTAACAGAAGAGATTGCGGCTCGTTCGATT
TATGGATATATCGAAGGAGAGCTCGGCCTACAGATCAGCTATGCCAAACGAAAGATTGCAGCGGAAGACGTGACCGAGCT
CGACCGGAAGCGGCTCGACTTGCATGATTACGAATATGTCATCGTCATCACGAACGATACGTTCTTATATGAAGGACAAC
AATTTGAATACACGGAGTCACGTCACCGCTTGGACAAGTTCCAGTTCAGTGATGTCGCCCGGCGCTAA

Upstream 100 bases:

>100_bases
GCATCTCGGACCTGGTGCAATCGGCATCACGTGGTATCGTCGCGAATGGTAAGAGAGACGACCGTCTAAGGTCGTCTTTT
TCAATGGAGGAGGGAATGTG

Downstream 100 bases:

>100_bases
AACCTCTTTCGTACAGGAAGAGGTTTTTTGTTTGATTGAAGGTGAGATAGGGAATTTTTTACAATGTAGAAGACACATAA
CCTTCACGTTTAACTTGTAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MAKYRQIFERLAEEMRNGTRPADSKLPSETELMHQFEASRGTVRKALDLLQENGYVRKHHGKGVFVLKRDQIEFQFNGIV
SFSEVYASMLGRSIQTHVASFEEMEAPTWLAERMNLATGTHVFRIERVRNFDGENVILDINYFVKDLVPGLTEEIAARSI
YGYIEGELGLQISYAKRKIAAEDVTELDRKRLDLHDYEYVIVITNDTFLYEGQQFEYTESRHRLDKFQFSDVARR

Sequences:

>Translated_235_residues
MAKYRQIFERLAEEMRNGTRPADSKLPSETELMHQFEASRGTVRKALDLLQENGYVRKHHGKGVFVLKRDQIEFQFNGIV
SFSEVYASMLGRSIQTHVASFEEMEAPTWLAERMNLATGTHVFRIERVRNFDGENVILDINYFVKDLVPGLTEEIAARSI
YGYIEGELGLQISYAKRKIAAEDVTELDRKRLDLHDYEYVIVITNDTFLYEGQQFEYTESRHRLDKFQFSDVARR
>Mature_234_residues
AKYRQIFERLAEEMRNGTRPADSKLPSETELMHQFEASRGTVRKALDLLQENGYVRKHHGKGVFVLKRDQIEFQFNGIVS
FSEVYASMLGRSIQTHVASFEEMEAPTWLAERMNLATGTHVFRIERVRNFDGENVILDINYFVKDLVPGLTEEIAARSIY
GYIEGELGLQISYAKRKIAAEDVTELDRKRLDLHDYEYVIVITNDTFLYEGQQFEYTESRHRLDKFQFSDVARR

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=27.6595744680851, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790118, Length=215, Percent_Identity=26.5116279069767, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790540, Length=229, Percent_Identity=24.0174672489083, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082252, Length=169, Percent_Identity=26.6272189349112, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27431; Mature: 27300

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYRQIFERLAEEMRNGTRPADSKLPSETELMHQFEASRGTVRKALDLLQENGYVRKHH
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEC
GKGVFVLKRDQIEFQFNGIVSFSEVYASMLGRSIQTHVASFEEMEAPTWLAERMNLATGT
CCEEEEEEECCEEEEECCEECHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
HVFRIERVRNFDGENVILDINYFVKDLVPGLTEEIAARSIYGYIEGELGLQISYAKRKIA
HHEEEHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHEEECCCCEEEHHHHHHHH
AEDVTELDRKRLDLHDYEYVIVITNDTFLYEGQQFEYTESRHRLDKFQFSDVARR
HHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKYRQIFERLAEEMRNGTRPADSKLPSETELMHQFEASRGTVRKALDLLQENGYVRKHH
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEC
GKGVFVLKRDQIEFQFNGIVSFSEVYASMLGRSIQTHVASFEEMEAPTWLAERMNLATGT
CCEEEEEEECCEEEEECCEECHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
HVFRIERVRNFDGENVILDINYFVKDLVPGLTEEIAARSIYGYIEGELGLQISYAKRKIA
HHEEEHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHEEECCCCEEEHHHHHHHH
AEDVTELDRKRLDLHDYEYVIVITNDTFLYEGQQFEYTESRHRLDKFQFSDVARR
HHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]