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The map label for this gene is acuC [H]

Identifier: 229916428

GI number: 229916428

Start: 654106

End: 655275

Strand: Direct

Name: acuC [H]

Synonym: EAT1b_0698

Alternate gene names: 229916428

Gene position: 654106-655275 (Clockwise)

Preceding gene: 229916427

Following gene: 229916433

Centisome position: 21.8

GC content: 52.91

Gene sequence:

>1170_bases
ATGAGACCGATTTACATATTTGGCGAAGACGAGACGTCTTATCGCTTCCATGAGGATCATCCGTTCAATCCCTTACGACT
GGAATTGACGACATCGCTATTGATCGCAGCCGGAAAACTGTCCAAATCGGAATGTGTGTCTCCTCCACTCGCTTCGGTTG
AAGCGTTAGCGCTCGTTCACGATCTCGATTACATCGAAGCCGTCCAAGCTGCGGCGGCAGGAGAACTTTCTACGCTGAAA
GCGAATAAGTTTGGTCTCGGTACGGAAGATACACCTATCTTTCCGACGATACATGAGGGGGCCGCTCGGCTTGTCGGCGG
GACGATTCACGCGCTCGACCTCGTCGCAAGCGGGAAAGCAGAACGCGCCTTCCATGTCGGGGGCGGCTTACACCATGGTA
TGCGGCGCAAAGCATCAGGGTTTTGCGTCTATAACGATGCAGCTGTCGCCATCGCACATGTGCGAAAACAATACGGGTCA
CGCGTTCTCTATGTCGATACGGATGCGCATCATGGGGACGGCGTCCAATGGCTCTTCTATGACGATGATGACGTGATGAC
ACTGTCGATTCATGAGACGGGACGTTATCTCTTCCCGGGTACCGGAATGGTGACAGAACGAGGCAATGGGAAAGGATACG
GCTACAGTTGGAACGTACCGGTCGATGCGTTCACCCAAGATGACTCTTTTTTGACGTGCTATGAGACCGTCTTACGTGAA
GCGTGCGAATGGTTCAAACCTGATATCATCCTGACCCAGAACGGTGCAGATGCCCATGTCTTTGATCCACTCACCCATCT
GGCATCAACGATACGGACGTTCGAACAAATCCCGCAGATTGCCTCACGCCTGGCCGATGAATATACAGACGGCCGTCTCG
TCGCCCTTGGTGGCGGCGGGTATGACTGGTATCGTGCCGTGCCACGCGCATGGGCTCAAGTGTGGGCTGGATTGACGAGA
GAAGCACCCTATTCTGGAGATATTCCGCGCGAGTGGATTGAGCAATGGTCTGGTGTCGCTGGTCAACCGTTACCCACTCG
CTGGGACGACTCGCTTTATGCGTTTGATCATATCCCGCGCCGTCAACAAATCGAAGAAAAGAATTGGGAAGTCACGAAAC
GAGCCTTTTGGCCGTTCATATCAAATGACCGAAAGTCAATTTACCTATAA

Upstream 100 bases:

>100_bases
AACGTATCATCTCCTTCCGCGTCCAGACGATGAACCCGCTCCGAATCATCGAACGGTTGAAACGTGAAGGCTATGATGTC
CTCGGTCCGGAGATGTCGCG

Downstream 100 bases:

>100_bases
AAATAAGCCTCCCCTTTCCCTCACATGATGTGGCGGATGGGGAGGCTTTTGATTAATCTTGGCGAAGCGAGTCACGACGC
TCGATTCGGTGAGGAAGTAC

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRPIYIFGEDETSYRFHEDHPFNPLRLELTTSLLIAAGKLSKSECVSPPLASVEALALVHDLDYIEAVQAAAAGELSTLK
ANKFGLGTEDTPIFPTIHEGAARLVGGTIHALDLVASGKAERAFHVGGGLHHGMRRKASGFCVYNDAAVAIAHVRKQYGS
RVLYVDTDAHHGDGVQWLFYDDDDVMTLSIHETGRYLFPGTGMVTERGNGKGYGYSWNVPVDAFTQDDSFLTCYETVLRE
ACEWFKPDIILTQNGADAHVFDPLTHLASTIRTFEQIPQIASRLADEYTDGRLVALGGGGYDWYRAVPRAWAQVWAGLTR
EAPYSGDIPREWIEQWSGVAGQPLPTRWDDSLYAFDHIPRRQQIEEKNWEVTKRAFWPFISNDRKSIYL

Sequences:

>Translated_389_residues
MRPIYIFGEDETSYRFHEDHPFNPLRLELTTSLLIAAGKLSKSECVSPPLASVEALALVHDLDYIEAVQAAAAGELSTLK
ANKFGLGTEDTPIFPTIHEGAARLVGGTIHALDLVASGKAERAFHVGGGLHHGMRRKASGFCVYNDAAVAIAHVRKQYGS
RVLYVDTDAHHGDGVQWLFYDDDDVMTLSIHETGRYLFPGTGMVTERGNGKGYGYSWNVPVDAFTQDDSFLTCYETVLRE
ACEWFKPDIILTQNGADAHVFDPLTHLASTIRTFEQIPQIASRLADEYTDGRLVALGGGGYDWYRAVPRAWAQVWAGLTR
EAPYSGDIPREWIEQWSGVAGQPLPTRWDDSLYAFDHIPRRQQIEEKNWEVTKRAFWPFISNDRKSIYL
>Mature_389_residues
MRPIYIFGEDETSYRFHEDHPFNPLRLELTTSLLIAAGKLSKSECVSPPLASVEALALVHDLDYIEAVQAAAAGELSTLK
ANKFGLGTEDTPIFPTIHEGAARLVGGTIHALDLVASGKAERAFHVGGGLHHGMRRKASGFCVYNDAAVAIAHVRKQYGS
RVLYVDTDAHHGDGVQWLFYDDDDVMTLSIHETGRYLFPGTGMVTERGNGKGYGYSWNVPVDAFTQDDSFLTCYETVLRE
ACEWFKPDIILTQNGADAHVFDPLTHLASTIRTFEQIPQIASRLADEYTDGRLVALGGGGYDWYRAVPRAWAQVWAGLTR
EAPYSGDIPREWIEQWSGVAGQPLPTRWDDSLYAFDHIPRRQQIEEKNWEVTKRAFWPFISNDRKSIYL

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=328, Percent_Identity=34.1463414634146, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI13128860, Length=325, Percent_Identity=32.9230769230769, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI293336691, Length=273, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI8923769, Length=332, Percent_Identity=32.8313253012048, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI262073092, Length=248, Percent_Identity=34.2741935483871, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI262073088, Length=202, Percent_Identity=37.6237623762376, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI17158039, Length=341, Percent_Identity=31.6715542521994, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI30795204, Length=341, Percent_Identity=31.6715542521994, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI30795202, Length=341, Percent_Identity=31.6715542521994, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI20070354, Length=315, Percent_Identity=30.7936507936508, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI153085395, Length=265, Percent_Identity=30.9433962264151, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI169234807, Length=263, Percent_Identity=31.5589353612167, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI148539870, Length=263, Percent_Identity=31.5589353612167, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI13128864, Length=310, Percent_Identity=30, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226529806, Length=233, Percent_Identity=33.4763948497854, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI62750347, Length=330, Percent_Identity=29.3939393939394, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI62750349, Length=330, Percent_Identity=29.3939393939394, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI209862883, Length=253, Percent_Identity=26.8774703557312, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI217272877, Length=250, Percent_Identity=28.4, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262072965, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508561, Length=331, Percent_Identity=32.9305135951662, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17561978, Length=325, Percent_Identity=33.2307692307692, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17534739, Length=311, Percent_Identity=31.8327974276527, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=337, Percent_Identity=29.9703264094956, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540334, Length=331, Percent_Identity=29.9093655589124, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=317, Percent_Identity=30.2839116719243, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=317, Percent_Identity=30.2839116719243, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17537347, Length=260, Percent_Identity=23.8461538461538, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=285, Percent_Identity=23.859649122807, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323999, Length=338, Percent_Identity=30.7692307692308, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6321244, Length=336, Percent_Identity=30.3571428571429, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324307, Length=287, Percent_Identity=31.3588850174216, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325325, Length=213, Percent_Identity=28.6384976525822, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24657891, Length=331, Percent_Identity=31.4199395770393, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24644244, Length=334, Percent_Identity=30.8383233532934, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI281360799, Length=217, Percent_Identity=33.1797235023041, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24641720, Length=217, Percent_Identity=33.1797235023041, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281360801, Length=217, Percent_Identity=33.1797235023041, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24642146, Length=289, Percent_Identity=26.2975778546713, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360899, Length=289, Percent_Identity=26.2975778546713, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24642144, Length=289, Percent_Identity=26.2975778546713, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24642142, Length=289, Percent_Identity=26.2975778546713, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24649807, Length=258, Percent_Identity=23.6434108527132, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 43497; Mature: 43497

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIYIFGEDETSYRFHEDHPFNPLRLELTTSLLIAAGKLSKSECVSPPLASVEALALVH
CCEEEEECCCCCCEEECCCCCCCCEEEEEHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHH
DLDYIEAVQAAAAGELSTLKANKFGLGTEDTPIFPTIHEGAARLVGGTIHALDLVASGKA
HHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCC
ERAFHVGGGLHHGMRRKASGFCVYNDAAVAIAHVRKQYGSRVLYVDTDAHHGDGVQWLFY
CCEEECCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEE
DDDDVMTLSIHETGRYLFPGTGMVTERGNGKGYGYSWNVPVDAFTQDDSFLTCYETVLRE
CCCCEEEEEEECCCCEEECCCCEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
ACEWFKPDIILTQNGADAHVFDPLTHLASTIRTFEQIPQIASRLADEYTDGRLVALGGGG
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
YDWYRAVPRAWAQVWAGLTREAPYSGDIPREWIEQWSGVAGQPLPTRWDDSLYAFDHIPR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEHHCCCC
RQQIEEKNWEVTKRAFWPFISNDRKSIYL
HHHHHHCCCHHHHHHHCCCCCCCCCEECC
>Mature Secondary Structure
MRPIYIFGEDETSYRFHEDHPFNPLRLELTTSLLIAAGKLSKSECVSPPLASVEALALVH
CCEEEEECCCCCCEEECCCCCCCCEEEEEHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHH
DLDYIEAVQAAAAGELSTLKANKFGLGTEDTPIFPTIHEGAARLVGGTIHALDLVASGKA
HHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCC
ERAFHVGGGLHHGMRRKASGFCVYNDAAVAIAHVRKQYGSRVLYVDTDAHHGDGVQWLFY
CCEEECCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEE
DDDDVMTLSIHETGRYLFPGTGMVTERGNGKGYGYSWNVPVDAFTQDDSFLTCYETVLRE
CCCCEEEEEEECCCCEEECCCCEEEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
ACEWFKPDIILTQNGADAHVFDPLTHLASTIRTFEQIPQIASRLADEYTDGRLVALGGGG
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
YDWYRAVPRAWAQVWAGLTREAPYSGDIPREWIEQWSGVAGQPLPTRWDDSLYAFDHIPR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEHHCCCC
RQQIEEKNWEVTKRAFWPFISNDRKSIYL
HHHHHHCCCHHHHHHHCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]