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The map label for this gene is infC [H]

Identifier: 229916378

GI number: 229916378

Start: 599748

End: 600278

Strand: Reverse

Name: infC [H]

Synonym: EAT1b_0648

Alternate gene names: 229916378

Gene position: 600278-599748 (Counterclockwise)

Preceding gene: 229916380

Following gene: 229916377

Centisome position: 20.01

GC content: 45.95

Gene sequence:

>531_bases
ATGGAGGTGCTAACCATTAGCAAAGAGCTCTTTATCAACGAAAACATTCGTGCCCGTGAAGTACGTCTCATTGGCGCAGA
CGGTGCACAACTCGGTGTGACATCACGTAACGATGCGTTACGTTTAGCTGAAGAAGCGGAACTAGACCTCGTCTTAGTCG
CGGATAAAGCAAATCCACCGGTCGCTAAAATTATGGATTATGGGAAGTACCGATTCGAACTCCAGAAGAAGGAGAAAGAA
GCGCGTAAAAACCAAAAAGTCATCCAAATGAAAGAAGTGCGTCTCAGTCCAACAATCGAGGACAACGATTTCCAAACAAA
ATTGCGTAATGCACGCAAGTTCCTTGAAAAAGGAAACAAAGTGAAGGCTTCGATTCGTTTCCGCGGACGTGCCATCACAC
ACTCGGAAATCGGGAAACGTGTTTTGGACAAAATGGCAGCGGAATGTGCCGATTTGGCAACAGTTGAACAAAAGCCGAAG
ATGGAAGGACGCAGCATGTTCTTAGTGCTGGCTCCGAACAAAGAAGATTAA

Upstream 100 bases:

>100_bases
CTGCCGTTTTATGACCTCAACTGATGTGTGGGTGGGAAACTGCCGACGCTTTTTTTATTGCCATGTTGTCTTGTCAATCT
AAATCTCGTGCAATCGCACG

Downstream 100 bases:

>100_bases
TTATCGATTCTCAGTGGGGAGGAAATACTCATGCCGAAAATGAAATCGCACCGCGGTGCTTCAAAACGTTTCAAACGTAC
AGCATCAGGTAAACTCAAGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MEVLTISKELFINENIRAREVRLIGADGAQLGVTSRNDALRLAEEAELDLVLVADKANPPVAKIMDYGKYRFELQKKEKE
ARKNQKVIQMKEVRLSPTIEDNDFQTKLRNARKFLEKGNKVKASIRFRGRAITHSEIGKRVLDKMAAECADLATVEQKPK
MEGRSMFLVLAPNKED

Sequences:

>Translated_176_residues
MEVLTISKELFINENIRAREVRLIGADGAQLGVTSRNDALRLAEEAELDLVLVADKANPPVAKIMDYGKYRFELQKKEKE
ARKNQKVIQMKEVRLSPTIEDNDFQTKLRNARKFLEKGNKVKASIRFRGRAITHSEIGKRVLDKMAAECADLATVEQKPK
MEGRSMFLVLAPNKED
>Mature_176_residues
MEVLTISKELFINENIRAREVRLIGADGAQLGVTSRNDALRLAEEAELDLVLVADKANPPVAKIMDYGKYRFELQKKEKE
ARKNQKVIQMKEVRLSPTIEDNDFQTKLRNARKFLEKGNKVKASIRFRGRAITHSEIGKRVLDKMAAECADLATVEQKPK
MEGRSMFLVLAPNKED

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=50.609756097561, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20028; Mature: 20028

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLTISKELFINENIRAREVRLIGADGAQLGVTSRNDALRLAEEAELDLVLVADKANPP
CCEEEECHHHEECCCCCEEEEEEEECCCCEECCCCCCCHHEECCCCCEEEEEEECCCCCC
VAKIMDYGKYRFELQKKEKEARKNQKVIQMKEVRLSPTIEDNDFQTKLRNARKFLEKGNK
HHHHHHCCHHEEEEHHHHHHHHHHHHHEEHEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
VKASIRFRGRAITHSEIGKRVLDKMAAECADLATVEQKPKMEGRSMFLVLAPNKED
EEEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MEVLTISKELFINENIRAREVRLIGADGAQLGVTSRNDALRLAEEAELDLVLVADKANPP
CCEEEECHHHEECCCCCEEEEEEEECCCCEECCCCCCCHHEECCCCCEEEEEEECCCCCC
VAKIMDYGKYRFELQKKEKEARKNQKVIQMKEVRLSPTIEDNDFQTKLRNARKFLEKGNK
HHHHHHCCHHEEEEHHHHHHHHHHHHHEEHEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
VKASIRFRGRAITHSEIGKRVLDKMAAECADLATVEQKPKMEGRSMFLVLAPNKED
EEEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]