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The map label for this gene is tlpB [H]

Identifier: 229916361

GI number: 229916361

Start: 583860

End: 585503

Strand: Reverse

Name: tlpB [H]

Synonym: EAT1b_0631

Alternate gene names: 229916361

Gene position: 585503-583860 (Counterclockwise)

Preceding gene: 229916362

Following gene: 229916360

Centisome position: 19.52

GC content: 49.15

Gene sequence:

>1644_bases
ATGAGTTTACGTAAACGTTTTATCTTCTCAACCGTCTTCACCGTCGTCTTGATCGTACTGATGATGAGTTACGTCTTGTC
GACGTTGAATCGCTTGCAAACGTATAACGAGCAGTATGGAAGTCAAATGATTGAATTGTCTCAACTTGAAACGTCACTCC
TACAAGAACAATCCCTCTGGACGTCACTTGGTGAACAGTCGAACCAATCTACATTGACTCAATTAGAGCGCATCCGTGTG
ACGAACGCGGAAACGTTCGATGATTTAAAACAGTCTTATTTGATTCCGGCATTTTCAAATCATTTAGACCGTGCCACGAT
GAAGTACGAACAGGTGAACGAAGATGTCGAGTCGGCACTTGAAGGTGGTATCGGGGCTCGGATTCAGGCAGCAAAACTGG
AAGGTTTGTTAAATGATATCAATACGTTGATTGCAAAGAACGGTTCATTCTATGAAGCGCTTCAAGTGGAGGCGGCAAAT
GAGACGGAACGTCTCTTGTTGATCTCGGTCCTCTTGACGATTCTCGTCATCCTAGCGCTCGGAATCTACAACTTCTTCTT
TGCCCGTTCGATCACTCGACCACTCGAAAAAAATGTCAAGGTGGCCGAAGCGATTGCAGCCGGACGTCTCGTCACGTTGC
CTGAGTCGACGCGCAATGATGAAATCGGACGTCTTGAACGTGCCATGCGTGACATGACGGCGTCTCTTCAGACGGTGATC
GGGTCAATCCGAGTCACATCAATGAAAGTGAACGGGATGACCGAAACGGCCGCGGCCGAAAATGAAGCGGTCGTGAGTAC
GACATCTAACATCACGAACGCAGTTGATGAGATGGCACACGGAGCACAGTCGATTGCAAATGAGTTGCAAGAAACGCTCA
GCTCAGTGCATACGATGGCGACTTCATTTGAGACGAGCTTGAACCAGACGAAACAAACGACGGAAGAAACGTCAGAAATG
ACACGTGAAGTAGCGGCTGGGATTGAAACATTAACGGACCAGGAGCACATTTTAGATCGCTCAAGCGAACGGAATGAAGT
GCTTGTTTCGCGAATGGACCACTTTGCACGACAAACGGCTGAGATTGAGGCGATGGCGAAGCTTGTCGAAGACGTCGCGG
CTCAAACGAATTTACTTGCCCTCAATGCGGCAATCGAGGCAGCCCGTGCGGGAGAAGCGGGACGAGGATTTGCTGTCGTA
GCAAGTGAAGTGAAGAAGTTGGCGGAAGAGAGCAACAAGGCGACTCGCTCTATTTTCCACGTCGTCGAGACGATCCAGCA
AGAAGTCGTCCGTTTGACGGAAACGGTGAATGAGTCAAAACGCGAGCAAGAGGCGCAATTAGAAGCGTTCGGATTGACGA
AAGAAGCATTCAACCGAATCCATGAACGGACAGACCACGTCGCTTCGTTCGTACGCACGATCGAACAAGAGATGCGCACA
TCGAGTAACGAGGTAAACAACGTCTTGCGTCGGGTTGAAGAAGTATCTGGGGTGACGGAAGAGTTGGCCGCAGGAAACGA
AGAAGTGGCAGCCTCGATGAAAGAACAGCAGGCAAGCTTCGATCAAATCTTTACATTGATGCAAGAGTTAGAAGGACAGG
CAGCGGCACTCGCTGACCAGGTTCAGCATTTCGAAGAAGAATAA

Upstream 100 bases:

>100_bases
GCGGCGTCGGCTTGGCTCCGCTTCGTCGCATTCAATGGGATGAGAAAGAAACATCAGAGTATGAATCGGTAGAACGTCAG
TTGAAGGAGGGGACACTTAA

Downstream 100 bases:

>100_bases
TCGAACAGTGAACAGTAGGAACGGAGGCCACGTGATGGTCTCCGTTTTTTCCGTCATTCTATAACCTGTTCATAGAAATT
GTGTCGATGAATATCGTTAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSLRKRFIFSTVFTVVLIVLMMSYVLSTLNRLQTYNEQYGSQMIELSQLETSLLQEQSLWTSLGEQSNQSTLTQLERIRV
TNAETFDDLKQSYLIPAFSNHLDRATMKYEQVNEDVESALEGGIGARIQAAKLEGLLNDINTLIAKNGSFYEALQVEAAN
ETERLLLISVLLTILVILALGIYNFFFARSITRPLEKNVKVAEAIAAGRLVTLPESTRNDEIGRLERAMRDMTASLQTVI
GSIRVTSMKVNGMTETAAAENEAVVSTTSNITNAVDEMAHGAQSIANELQETLSSVHTMATSFETSLNQTKQTTEETSEM
TREVAAGIETLTDQEHILDRSSERNEVLVSRMDHFARQTAEIEAMAKLVEDVAAQTNLLALNAAIEAARAGEAGRGFAVV
ASEVKKLAEESNKATRSIFHVVETIQQEVVRLTETVNESKREQEAQLEAFGLTKEAFNRIHERTDHVASFVRTIEQEMRT
SSNEVNNVLRRVEEVSGVTEELAAGNEEVAASMKEQQASFDQIFTLMQELEGQAAALADQVQHFEEE

Sequences:

>Translated_547_residues
MSLRKRFIFSTVFTVVLIVLMMSYVLSTLNRLQTYNEQYGSQMIELSQLETSLLQEQSLWTSLGEQSNQSTLTQLERIRV
TNAETFDDLKQSYLIPAFSNHLDRATMKYEQVNEDVESALEGGIGARIQAAKLEGLLNDINTLIAKNGSFYEALQVEAAN
ETERLLLISVLLTILVILALGIYNFFFARSITRPLEKNVKVAEAIAAGRLVTLPESTRNDEIGRLERAMRDMTASLQTVI
GSIRVTSMKVNGMTETAAAENEAVVSTTSNITNAVDEMAHGAQSIANELQETLSSVHTMATSFETSLNQTKQTTEETSEM
TREVAAGIETLTDQEHILDRSSERNEVLVSRMDHFARQTAEIEAMAKLVEDVAAQTNLLALNAAIEAARAGEAGRGFAVV
ASEVKKLAEESNKATRSIFHVVETIQQEVVRLTETVNESKREQEAQLEAFGLTKEAFNRIHERTDHVASFVRTIEQEMRT
SSNEVNNVLRRVEEVSGVTEELAAGNEEVAASMKEQQASFDQIFTLMQELEGQAAALADQVQHFEEE
>Mature_546_residues
SLRKRFIFSTVFTVVLIVLMMSYVLSTLNRLQTYNEQYGSQMIELSQLETSLLQEQSLWTSLGEQSNQSTLTQLERIRVT
NAETFDDLKQSYLIPAFSNHLDRATMKYEQVNEDVESALEGGIGARIQAAKLEGLLNDINTLIAKNGSFYEALQVEAANE
TERLLLISVLLTILVILALGIYNFFFARSITRPLEKNVKVAEAIAAGRLVTLPESTRNDEIGRLERAMRDMTASLQTVIG
SIRVTSMKVNGMTETAAAENEAVVSTTSNITNAVDEMAHGAQSIANELQETLSSVHTMATSFETSLNQTKQTTEETSEMT
REVAAGIETLTDQEHILDRSSERNEVLVSRMDHFARQTAEIEAMAKLVEDVAAQTNLLALNAAIEAARAGEAGRGFAVVA
SEVKKLAEESNKATRSIFHVVETIQQEVVRLTETVNESKREQEAQLEAFGLTKEAFNRIHERTDHVASFVRTIEQEMRTS
SNEVNNVLRRVEEVSGVTEELAAGNEEVAASMKEQQASFDQIFTLMQELEGQAAALADQVQHFEEE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=259, Percent_Identity=28.1853281853282, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787690, Length=370, Percent_Identity=27.8378378378378, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=316, Percent_Identity=27.5316455696203, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788194, Length=413, Percent_Identity=24.9394673123487, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788195, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60733; Mature: 60602

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRKRFIFSTVFTVVLIVLMMSYVLSTLNRLQTYNEQYGSQMIELSQLETSLLQEQSLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLGEQSNQSTLTQLERIRVTNAETFDDLKQSYLIPAFSNHLDRATMKYEQVNEDVESAL
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EGGIGARIQAAKLEGLLNDINTLIAKNGSFYEALQVEAANETERLLLISVLLTILVILAL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GIYNFFFARSITRPLEKNVKVAEAIAAGRLVTLPESTRNDEIGRLERAMRDMTASLQTVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
GSIRVTSMKVNGMTETAAAENEAVVSTTSNITNAVDEMAHGAQSIANELQETLSSVHTMA
HHHHHEEEEECCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFETSLNQTKQTTEETSEMTREVAAGIETLTDQEHILDRSSERNEVLVSRMDHFARQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
EIEAMAKLVEDVAAQTNLLALNAAIEAARAGEAGRGFAVVASEVKKLAEESNKATRSIFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVETIQQEVVRLTETVNESKREQEAQLEAFGLTKEAFNRIHERTDHVASFVRTIEQEMRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSNEVNNVLRRVEEVSGVTEELAAGNEEVAASMKEQQASFDQIFTLMQELEGQAAALADQ
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VQHFEEE
HHHHCCC
>Mature Secondary Structure 
SLRKRFIFSTVFTVVLIVLMMSYVLSTLNRLQTYNEQYGSQMIELSQLETSLLQEQSLW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLGEQSNQSTLTQLERIRVTNAETFDDLKQSYLIPAFSNHLDRATMKYEQVNEDVESAL
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EGGIGARIQAAKLEGLLNDINTLIAKNGSFYEALQVEAANETERLLLISVLLTILVILAL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GIYNFFFARSITRPLEKNVKVAEAIAAGRLVTLPESTRNDEIGRLERAMRDMTASLQTVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
GSIRVTSMKVNGMTETAAAENEAVVSTTSNITNAVDEMAHGAQSIANELQETLSSVHTMA
HHHHHEEEEECCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFETSLNQTKQTTEETSEMTREVAAGIETLTDQEHILDRSSERNEVLVSRMDHFARQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
EIEAMAKLVEDVAAQTNLLALNAAIEAARAGEAGRGFAVVASEVKKLAEESNKATRSIFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVETIQQEVVRLTETVNESKREQEAQLEAFGLTKEAFNRIHERTDHVASFVRTIEQEMRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSNEVNNVLRRVEEVSGVTEELAAGNEEVAASMKEQQASFDQIFTLMQELEGQAAALADQ
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VQHFEEE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]