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The map label for this gene is prmA

Identifier: 229916344

GI number: 229916344

Start: 565580

End: 566518

Strand: Reverse

Name: prmA

Synonym: EAT1b_0614

Alternate gene names: 229916344

Gene position: 566518-565580 (Counterclockwise)

Preceding gene: 229916345

Following gene: 229916343

Centisome position: 18.88

GC content: 50.05

Gene sequence:

>939_bases
ATGAAATGGTCTGAAATTTGTGTCCACACGACACAACTTGCGGTAGAAGCGGTATCCAATTTACTACACGAAGTGGGGGC
ACAAGGTGTCGTCATCGAGGACGTGGAAGATTTCGATAGAATGATGGCGGAGGACCATTTCGGGGAGATTTGGGACGTTT
CGGATCGTGAGACGTATCCAACTTCTGGCGTACACGTCAAAGCGTATGTCCCGGCCTCGGGAGATTTTCAAGATTTACTT
TCAAATCTGAAAAAAGAAATCGAACGACTACGCACGATGCTCGATATCGGGTCAGGAGACGTCACGGTCGCTGAAATCGA
TGAAGAGGACTGGGCTCACTCTTGGAAGCAGTATTATAAGCCGGTGAAAATTTCGCAACAGCTTACCATTGTTCCTTTAT
GGGAAGAGTACACACCGCAGCCGGAAGAGAATGTGATTTTGCTTGACCCAGGTATGGCGTTCGGCACAGGAACGCATCCG
ACGACAATGCTATGCATTCAAGCGATTGAGAACTACATCCGGGAAGGTGACCATGTCATTGATGTCGGTACAGGATCGGG
CGTATTGTCGATTGCTGCTGCGAAACTCGGAGCAGCAAGCGTGAAGGCGCTAGATTTGGATTCAGTCGCCGTTGAATCGG
CTCGTCAAAACGTTGAGACGAACGGAGTGGGCGAACTCGTTCAAGTGGACACAGGTGATCTTCTGAAAGGTGTGGAAGGG
GAGTATGATTTAGTCGTGGCGAACATTCTCGCTGACGTCATTCTCCTGTTCATCGAAGACGCCTATGCACGTACGAAGTC
AGGTGGTCGCTTCATCACCTCTGGAATTATCGGAGAGAAGCGGGCTGAAGTGACGAATGCTTTGGTCGCTGCTGGATTTG
AGATCGAAGAGACGCGCGTGATGGAAGATTGGGTCGCGATTATCGCCAAGAAGGGGTAA

Upstream 100 bases:

>100_bases
ATTTGAAGAAATTAGCGGAGAGTCCGGTGTCGAAGAGGAACATGGCATGTTCCAAAAAATGAAAAAGTTCTTTAGTCACT
AAAAGGAGTGTGTACGAACG

Downstream 100 bases:

>100_bases
GTTATGCAACGTTATTTTTTGACAAAAGAAGCCTTTAAAGGCGAAACGGTGACCCTTCCTTCCGACGTGGTCCATCACAT
CGGTACAGTCTTACGACAAG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKWSEICVHTTQLAVEAVSNLLHEVGAQGVVIEDVEDFDRMMAEDHFGEIWDVSDRETYPTSGVHVKAYVPASGDFQDLL
SNLKKEIERLRTMLDIGSGDVTVAEIDEEDWAHSWKQYYKPVKISQQLTIVPLWEEYTPQPEENVILLDPGMAFGTGTHP
TTMLCIQAIENYIREGDHVIDVGTGSGVLSIAAAKLGAASVKALDLDSVAVESARQNVETNGVGELVQVDTGDLLKGVEG
EYDLVVANILADVILLFIEDAYARTKSGGRFITSGIIGEKRAEVTNALVAAGFEIEETRVMEDWVAIIAKKG

Sequences:

>Translated_312_residues
MKWSEICVHTTQLAVEAVSNLLHEVGAQGVVIEDVEDFDRMMAEDHFGEIWDVSDRETYPTSGVHVKAYVPASGDFQDLL
SNLKKEIERLRTMLDIGSGDVTVAEIDEEDWAHSWKQYYKPVKISQQLTIVPLWEEYTPQPEENVILLDPGMAFGTGTHP
TTMLCIQAIENYIREGDHVIDVGTGSGVLSIAAAKLGAASVKALDLDSVAVESARQNVETNGVGELVQVDTGDLLKGVEG
EYDLVVANILADVILLFIEDAYARTKSGGRFITSGIIGEKRAEVTNALVAAGFEIEETRVMEDWVAIIAKKG
>Mature_312_residues
MKWSEICVHTTQLAVEAVSNLLHEVGAQGVVIEDVEDFDRMMAEDHFGEIWDVSDRETYPTSGVHVKAYVPASGDFQDLL
SNLKKEIERLRTMLDIGSGDVTVAEIDEEDWAHSWKQYYKPVKISQQLTIVPLWEEYTPQPEENVILLDPGMAFGTGTHP
TTMLCIQAIENYIREGDHVIDVGTGSGVLSIAAAKLGAASVKALDLDSVAVESARQNVETNGVGELVQVDTGDLLKGVEG
EYDLVVANILADVILLFIEDAYARTKSGGRFITSGIIGEKRAEVTNALVAAGFEIEETRVMEDWVAIIAKKG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=260, Percent_Identity=33.4615384615385, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_EXISA (C4L423)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002884990.1
- ProteinModelPortal:   C4L423
- GeneID:   7871353
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0614
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34123; Mature: 34123

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEICVHTTQLAVEAVSNLLHEVGAQGVVIEDVEDFDRMMAEDHFGEIWDVSDRETYP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCCC
TSGVHVKAYVPASGDFQDLLSNLKKEIERLRTMLDIGSGDVTVAEIDEEDWAHSWKQYYK
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCC
PVKISQQLTIVPLWEEYTPQPEENVILLDPGMAFGTGTHPTTMLCIQAIENYIREGDHVI
CEECCCCEEEEECHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DVGTGSGVLSIAAAKLGAASVKALDLDSVAVESARQNVETNGVGELVQVDTGDLLKGVEG
EECCCCCHHHHHHHHHCHHHEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHCCCC
EYDLVVANILADVILLFIEDAYARTKSGGRFITSGIIGEKRAEVTNALVAAGFEIEETRV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
MEDWVAIIAKKG
HHHHHHHHHCCC
>Mature Secondary Structure
MKWSEICVHTTQLAVEAVSNLLHEVGAQGVVIEDVEDFDRMMAEDHFGEIWDVSDRETYP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCCC
TSGVHVKAYVPASGDFQDLLSNLKKEIERLRTMLDIGSGDVTVAEIDEEDWAHSWKQYYK
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCC
PVKISQQLTIVPLWEEYTPQPEENVILLDPGMAFGTGTHPTTMLCIQAIENYIREGDHVI
CEECCCCEEEEECHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DVGTGSGVLSIAAAKLGAASVKALDLDSVAVESARQNVETNGVGELVQVDTGDLLKGVEG
EECCCCCHHHHHHHHHCHHHEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHCCCC
EYDLVVANILADVILLFIEDAYARTKSGGRFITSGIIGEKRAEVTNALVAAGFEIEETRV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
MEDWVAIIAKKG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA